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The map label for this gene is motA

Identifier: 51596730

GI number: 51596730

Start: 2843306

End: 2844193

Strand: Reverse

Name: motA

Synonym: YPTB2407

Alternate gene names: 51596730

Gene position: 2844193-2843306 (Counterclockwise)

Preceding gene: 51596731

Following gene: 51596729

Centisome position: 59.94

GC content: 48.87

Gene sequence:

>888_bases
GTGTTAGTTATTTTGGGTTATCTCGTGGTCTTAGGTGCGGTTTTCGGTGGCTATATGCTCGTCGGTGGCCATTTGGGTGC
ACTCTATCAGCCAGCGGAATTTTTGATTATCGCTGGCGCGGGTATTGGCGCATTTATTGTGGGAAATAACGGTAAAGCAA
TAAAAGCCACAATGCGTGCGATGCCGAAGCTGATGCGCCGTTCTAAATATAACAAAGCCCTTTATATGGATTTAATGGCG
TTACTTTACCGCTTATTGGCGAAATCACGCCAACAGGGAATGCTGTCGTTGGAAAGGGACATAGAAAATCCGTTGGAAAG
TGAAATTTTCTCTAATTATCCACGGATTATGGCCGATAAGACATTAGTCGAATTTATTACCGATTATTTACGGCTCATTG
TGAGTGGAAATATGAACGCTTTTGAAATTGAAGCGTTGATGGATGAAGAGATTGAAACGCACGAGCAAGAGTCTGAGGTG
CCTGCCGGTAGTCTGGCGATGGTGGGGGATTCGTTACCGGCATTTGGTATCGTTGCTGCCGTCATGGGCGTGGTACATGC
CTTGGCTTCCGCTGACCGGCCAGCCGCGGAGCTTGGTGCCCTGATCGCTCATGCCATGGTGGGTACGTTCCTCGGTATTT
TGTTGGCGTATGGATTTATTTCCCCCTTGGCAACCTTATTACGCCAGCAAAGCGCAGAAACGACCAAAATGATGCAATGC
ATCAAAGTGACTCTGCTGTCCAGCTTGAACGGCTATGCACCGCAGATCGCGGTAGAGTTTGGTCGTAAAACGCTCTATAC
CACGGAGCGTCCATCCTTTATTGAGCTGGAAGAGCATGTGCGCCGAGTGAAAGCACCGGCATCGCAAGCGACGGAAGAGG
ACGCATGA

Upstream 100 bases:

>100_bases
GGTATGGAGACCGTTTCTGTTGACCGTCAATGACATTTTATGGCCCTCAAAGAGTGTTAACGCCTCACCTTCCACCCACA
CACTTTGCTAAGGATGTCGC

Downstream 100 bases:

>100_bases
AGCATCAGAACCACCCCGTTATTCTGGTCAAAAAGCGCAAAACTAAGCATGGTGCTGCGCATTACGGTGGGTCATGGAAA
ATCGCTTACGCTGACTTTAT

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLVILGYLVVLGAVFGGYMLVGGHLGALYQPAEFLIIAGAGIGAFIVGNNGKAIKATMRAMPKLMRRSKYNKALYMDLMA
LLYRLLAKSRQQGMLSLERDIENPLESEIFSNYPRIMADKTLVEFITDYLRLIVSGNMNAFEIEALMDEEIETHEQESEV
PAGSLAMVGDSLPAFGIVAAVMGVVHALASADRPAAELGALIAHAMVGTFLGILLAYGFISPLATLLRQQSAETTKMMQC
IKVTLLSSLNGYAPQIAVEFGRKTLYTTERPSFIELEEHVRRVKAPASQATEEDA

Sequences:

>Translated_295_residues
MLVILGYLVVLGAVFGGYMLVGGHLGALYQPAEFLIIAGAGIGAFIVGNNGKAIKATMRAMPKLMRRSKYNKALYMDLMA
LLYRLLAKSRQQGMLSLERDIENPLESEIFSNYPRIMADKTLVEFITDYLRLIVSGNMNAFEIEALMDEEIETHEQESEV
PAGSLAMVGDSLPAFGIVAAVMGVVHALASADRPAAELGALIAHAMVGTFLGILLAYGFISPLATLLRQQSAETTKMMQC
IKVTLLSSLNGYAPQIAVEFGRKTLYTTERPSFIELEEHVRRVKAPASQATEEDA
>Mature_295_residues
MLVILGYLVVLGAVFGGYMLVGGHLGALYQPAEFLIIAGAGIGAFIVGNNGKAIKATMRAMPKLMRRSKYNKALYMDLMA
LLYRLLAKSRQQGMLSLERDIENPLESEIFSNYPRIMADKTLVEFITDYLRLIVSGNMNAFEIEALMDEEIETHEQESEV
PAGSLAMVGDSLPAFGIVAAVMGVVHALASADRPAAELGALIAHAMVGTFLGILLAYGFISPLATLLRQQSAETTKMMQC
IKVTLLSSLNGYAPQIAVEFGRKTLYTTERPSFIELEEHVRRVKAPASQATEEDA

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=295, Percent_Identity=81.3559322033898, Blast_Score=503, Evalue=1e-144,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 32095; Mature: 32095

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVILGYLVVLGAVFGGYMLVGGHLGALYQPAEFLIIAGAGIGAFIVGNNGKAIKATMRA
CHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEEECCCCEEEEECCCCCHHHHHHHH
MPKLMRRSKYNKALYMDLMALLYRLLAKSRQQGMLSLERDIENPLESEIFSNYPRIMADK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
TLVEFITDYLRLIVSGNMNAFEIEALMDEEIETHEQESEVPAGSLAMVGDSLPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHH
VMGVVHALASADRPAAELGALIAHAMVGTFLGILLAYGFISPLATLLRQQSAETTKMMQC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
IKVTLLSSLNGYAPQIAVEFGRKTLYTTERPSFIELEEHVRRVKAPASQATEEDA
HHHHHHHHCCCCCCHHHHHHCCHHEEECCCCCEEHHHHHHHHHHCCHHCCCCCCC
>Mature Secondary Structure
MLVILGYLVVLGAVFGGYMLVGGHLGALYQPAEFLIIAGAGIGAFIVGNNGKAIKATMRA
CHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEEECCCCEEEEECCCCCHHHHHHHH
MPKLMRRSKYNKALYMDLMALLYRLLAKSRQQGMLSLERDIENPLESEIFSNYPRIMADK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
TLVEFITDYLRLIVSGNMNAFEIEALMDEEIETHEQESEVPAGSLAMVGDSLPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHH
VMGVVHALASADRPAAELGALIAHAMVGTFLGILLAYGFISPLATLLRQQSAETTKMMQC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
IKVTLLSSLNGYAPQIAVEFGRKTLYTTERPSFIELEEHVRRVKAPASQATEEDA
HHHHHHHHCCCCCCHHHHHHCCHHEEECCCCCEEHHHHHHHHHHCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]