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The map label for this gene is yfeA

Identifier: 51596671

GI number: 51596671

Start: 2768745

End: 2769713

Strand: Direct

Name: yfeA

Synonym: YPTB2347

Alternate gene names: 51596671

Gene position: 2768745-2769713 (Clockwise)

Preceding gene: 51596669

Following gene: 51596672

Centisome position: 58.35

GC content: 43.96

Gene sequence:

>969_bases
ATGTTAATTAAGAAAAAAAGTCCTTATCTCAAAATGATAGAACGACTAAACTCCCCTTTTCTACGGGCTGCAGCCTTGTT
TACAATTGTCGCATTCTCATCGCTGATCAGTACCGCTGCTTTAGCAGAAAATAATCCCAGCGATACAGCCAAAAAATTCA
AAGTTGTGACTACATTCACAATCATTCAGGATATTGCACAAAATATCGCCGGTGATGTTGCCGTGGTGGAGTCAATAACC
AAGCCAGGCGCAGAGATTCATGACTATCAACCTACCCCACGAGATATTGTAAAAGCACAGTCAGCAGACCTTATCTTATG
GAATGGCATGAATCTGGAGCGTTGGTTTGAGAAGTTCTTCGAAAGTATTAAAGATGTCCCGTCTGCCGTCGTGACCGCAG
GTATTACACCCCTGCCTATCCGTGAAGGCCCCTATAGCGGCATTGCCAACCCACATGCCTGGATGTCGCCATCAAATGCG
CTAATATATATTGAGAATATCCGCAAAGCGTTAGTTGAACACGATCCCGCTCATGCAGAAACCTATAACCGTAACGCGCA
AGCCTATGCTGAAAAAATTAAGGCGCTAGATGCTCCACTGCGTGAGCGTTTATCTCGTATTCCTGCGGAACAGCGTTGGT
TAGTAACCAGTGAAGGGGCATTTAGTTATCTTGCCAAAGACTATGGTTTTAAAGAGGTTTACTTATGGCCAATCAATGCA
GAGCAACAAGGTATTCCGCAACAAGTTAGACACGTGATTGATATTATTCGCGAAAATAAAATTCCGGTGGTGTTTAGTGA
GAGTACTATTTCCGACAAACCCGCCAAACAAGTGAGTAAAGAAACCGGTGCACAATATGGCGGCGTGCTATATGTTGATT
CTCTGTCGGGCGAAAAAGGCCCGGTCCCCACTTACATCAGTTTAATTAACATGACTGTAGATACTATCGCTAAAGGATTC
GGTCAATGA

Upstream 100 bases:

>100_bases
AAGTAACTATTGGTAAGTTTTAGTTTATTGTATAAGGAGGCTTGACTTCATCGCTAATGGTATTGATAATCATTTTCATT
TGGAAAAAGAGAACATCGTG

Downstream 100 bases:

>100_bases
GCCACCCTGTTTTTGTCCGCCCTGAGCTGGTAGTGGATAACGTCACTGTCACTTATAACAATGGTCATACTGCCATTTAT
GACGCCAGTTTTTCACTAAC

Product: ABC transporter, periplasmic iron siderophore-binding protein YfeA

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MLIKKKSPYLKMIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAGDVAVVESIT
KPGAEIHDYQPTPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSNA
LIYIENIRKALVEHDPAHAETYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINA
EQQGIPQQVRHVIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINMTVDTIAKGF
GQ

Sequences:

>Translated_322_residues
MLIKKKSPYLKMIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAGDVAVVESIT
KPGAEIHDYQPTPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSNA
LIYIENIRKALVEHDPAHAETYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINA
EQQGIPQQVRHVIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINMTVDTIAKGF
GQ
>Mature_322_residues
MLIKKKSPYLKMIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFTIIQDIAQNIAGDVAVVESIT
KPGAEIHDYQPTPRDIVKAQSADLILWNGMNLERWFEKFFESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSNA
LIYIENIRKALVEHDPAHAETYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINA
EQQGIPQQVRHVIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKGPVPTYISLINMTVDTIAKGF
GQ

Specific function: Part of an ATP-driven transport system yfeABCD for chelated iron [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=251, Percent_Identity=22.7091633466135, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 35720; Mature: 35720

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKKKSPYLKMIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFT
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IIQDIAQNIAGDVAVVESITKPGAEIHDYQPTPRDIVKAQSADLILWNGMNLERWFEKFF
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHH
ESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSNALIYIENIRKALVEHDPAHAE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHH
TYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINA
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCEEEEEECCC
EQQGIPQQVRHVIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKG
CCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCC
PVPTYISLINMTVDTIAKGFGQ
CCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIKKKSPYLKMIERLNSPFLRAAALFTIVAFSSLISTAALAENNPSDTAKKFKVVTTFT
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IIQDIAQNIAGDVAVVESITKPGAEIHDYQPTPRDIVKAQSADLILWNGMNLERWFEKFF
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHH
ESIKDVPSAVVTAGITPLPIREGPYSGIANPHAWMSPSNALIYIENIRKALVEHDPAHAE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHH
TYNRNAQAYAEKIKALDAPLRERLSRIPAEQRWLVTSEGAFSYLAKDYGFKEVYLWPINA
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCEEEEEECCC
EQQGIPQQVRHVIDIIRENKIPVVFSESTISDKPAKQVSKETGAQYGGVLYVDSLSGEKG
CCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCC
PVPTYISLINMTVDTIAKGFGQ
CCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9495751; 11586360; 12142430 [H]