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The map label for this gene is gst

Identifier: 51596605

GI number: 51596605

Start: 2692485

End: 2693090

Strand: Direct

Name: gst

Synonym: YPTB2281

Alternate gene names: 51596605

Gene position: 2692485-2693090 (Clockwise)

Preceding gene: 51596604

Following gene: 51596611

Centisome position: 56.75

GC content: 45.38

Gene sequence:

>606_bases
ATGAAACTGTTCTATAAACCGGGTGCTTGTTCTCTGTCCCCCCATATTGTGTTGCGGGAAGCAGGACTAGATTTCAGCAT
TGAACGTGTTGATTTAGTGACAAAAAAGACTGAAACGGGTGCAGACTATTTAAGCATCAACCCCAAAGGACAAGTACCGG
CCTTAGTGCTGGATGACGGTAGCCTACTGACTGAAGGGGTAGCTATTGTGCAATATTTGGCAGATAAAGTCCCAGACCGC
CACTTGATTGCCCCATCAGGGACGCTCTCGCGCTATCATGCCATTGAGTGGCTGAATTTTATCGCGACTGAACTACATAA
AGGTTTTAGCCCACTATTTAATCCAAATACACCAGATGAGTATAAGACGATTGTCCGCGAGCGGCTGGATAAGCAATTCA
GCTACGTTGATAGCGTATTAGCAGAGCATGATTATCTACTAGGTAAAAAATTCAGTGTGGCAGATGCCTACTTATTTACC
GTTAGCCGTTGGGCTAATGCGTTAAATCTTCAAATCAAAGAACGCAGCCATTTGGATCAATATATGGCGCGGGTCGCTGA
ACGCCCTGCGGTAAAAGCAGCTTTAGCCGCCGAAGATATCAAGTAA

Upstream 100 bases:

>100_bases
TGCCCCCTCATAATTATATAACTTCACTGGCTGTATTTTTCGCTATCCTGCATTAGGATTAAAATGGTTTTTCCTTTCAG
TACTCTTTTAGGAGGTTGTG

Downstream 100 bases:

>100_bases
TAAATAATGAGAATCAATCAATTGCCCCCATCACTAGGGGGCAATTGAAAATGGTTAGATTACAGCCTAACCGCTGTAAA
CTGGCAGATAGGCGTCACAA

Product: glutathionine S-transferase

Products: NA

Alternate protein names: GST B1-1 [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKLFYKPGACSLSPHIVLREAGLDFSIERVDLVTKKTETGADYLSINPKGQVPALVLDDGSLLTEGVAIVQYLADKVPDR
HLIAPSGTLSRYHAIEWLNFIATELHKGFSPLFNPNTPDEYKTIVRERLDKQFSYVDSVLAEHDYLLGKKFSVADAYLFT
VSRWANALNLQIKERSHLDQYMARVAERPAVKAALAAEDIK

Sequences:

>Translated_201_residues
MKLFYKPGACSLSPHIVLREAGLDFSIERVDLVTKKTETGADYLSINPKGQVPALVLDDGSLLTEGVAIVQYLADKVPDR
HLIAPSGTLSRYHAIEWLNFIATELHKGFSPLFNPNTPDEYKTIVRERLDKQFSYVDSVLAEHDYLLGKKFSVADAYLFT
VSRWANALNLQIKERSHLDQYMARVAERPAVKAALAAEDIK
>Mature_201_residues
MKLFYKPGACSLSPHIVLREAGLDFSIERVDLVTKKTETGADYLSINPKGQVPALVLDDGSLLTEGVAIVQYLADKVPDR
HLIAPSGTLSRYHAIEWLNFIATELHKGFSPLFNPNTPDEYKTIVRERLDKQFSYVDSVLAEHDYLLGKKFSVADAYLFT
VSRWANALNLQIKERSHLDQYMARVAERPAVKAALAAEDIK

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=201, Percent_Identity=60.6965174129353, Blast_Score=251, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 22534; Mature: 22534

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFYKPGACSLSPHIVLREAGLDFSIERVDLVTKKTETGADYLSINPKGQVPALVLDDG
CCEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCEEEECCC
SLLTEGVAIVQYLADKVPDRHLIAPSGTLSRYHAIEWLNFIATELHKGFSPLFNPNTPDE
CHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
YKTIVRERLDKQFSYVDSVLAEHDYLLGKKFSVADAYLFTVSRWANALNLQIKERSHLDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEHHHHHHHH
YMARVAERPAVKAALAAEDIK
HHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MKLFYKPGACSLSPHIVLREAGLDFSIERVDLVTKKTETGADYLSINPKGQVPALVLDDG
CCEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCEEEECCC
SLLTEGVAIVQYLADKVPDRHLIAPSGTLSRYHAIEWLNFIATELHKGFSPLFNPNTPDE
CHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
YKTIVRERLDKQFSYVDSVLAEHDYLLGKKFSVADAYLFTVSRWANALNLQIKERSHLDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEHHHHHHHH
YMARVAERPAVKAALAAEDIK
HHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8761466; 8436105; 2661269; 8645008; 9655824 [H]