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The map label for this gene is tonB

Identifier: 51596443

GI number: 51596443

Start: 2495000

End: 2495746

Strand: Direct

Name: tonB

Synonym: YPTB2117

Alternate gene names: 51596443

Gene position: 2495000-2495746 (Clockwise)

Preceding gene: 51596440

Following gene: 51596446

Centisome position: 52.59

GC content: 49.0

Gene sequence:

>747_bases
ATGCAGCTAATAAAATTTTTCTCAGATCGACGGTTAACATGGTCACTCATTTTTTCAATAGGGTTGCACGGGAGTGTTGT
TGCGGCACTGCTGTACGTTTCCGTAGAGCAAATGAAAATTCAACCTGAAATTGAGGATACGCCTCTTGCTGTAACGATGG
TCAATATAGCGGAATTTGCTGCACCACAACCGGCTGCCGCCGCGCCAGAGCCAGTTCAAGAAACACCAGCCGTGCCCGAA
GAGACACCGCCTGTGCTTGAAGAGACACCACCGGAACCTGAAGAGCTGCCTGAGCCTGTTCCTGAACCCGTGAAACCCAA
GCCGAAGCCTGTTAAGAAAGAAGTTAAGAAGCCGGAAGTGAAGAAGACGCAAGCACCGCCGGATGACAAACCGTTTAAAT
CTGATGAGGCCGCGCTGGTTGCGAACAATGCACCGGTAAAATCGGCACCAGTTGCCTCAACACCTGGCTTATCAACATCC
GCTGGGCCAAAGGCACTGAGTAAGGCTAAACCCTCTTATCCGGCTCGAGCATTGGCTTTAGGGATTGAAGGGCAGGTTAA
AGTACAGTACGACATTGATGAGAGTGGGCGAGTGACGAATGTCAGAGTGTTAGAAGCAACACCACGTAATACTTTTGAGC
GTGAAGTGAAGCAGGTCATGCGTAAATGGCGTTTTGAAGCGGTCGCTGCTAAAAACTATGTGACTACCATTGTGTTCAAG
CTCGATGGCAAAATGGAAATGAATTAA

Upstream 100 bases:

>100_bases
CGTCATTTAGCGCTAATTAACGAGAATGTTTGTCGTTCCTTATTGAACATGATTGCTATTTGCATTTAAACTTGGCTGCA
TCAGAGGACATTGAATCATT

Downstream 100 bases:

>100_bases
ATAAGACTGTCACCAACCTCAGGGCCGCTTTTGCGGCCCTTCTTGTTTAATCAATACTCTCACATTCATTATTGAGTCGC
ACCTACTTCGAAATTACCTT

Product: transport protein TonB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MQLIKFFSDRRLTWSLIFSIGLHGSVVAALLYVSVEQMKIQPEIEDTPLAVTMVNIAEFAAPQPAAAAPEPVQETPAVPE
ETPPVLEETPPEPEELPEPVPEPVKPKPKPVKKEVKKPEVKKTQAPPDDKPFKSDEAALVANNAPVKSAPVASTPGLSTS
AGPKALSKAKPSYPARALALGIEGQVKVQYDIDESGRVTNVRVLEATPRNTFEREVKQVMRKWRFEAVAAKNYVTTIVFK
LDGKMEMN

Sequences:

>Translated_248_residues
MQLIKFFSDRRLTWSLIFSIGLHGSVVAALLYVSVEQMKIQPEIEDTPLAVTMVNIAEFAAPQPAAAAPEPVQETPAVPE
ETPPVLEETPPEPEELPEPVPEPVKPKPKPVKKEVKKPEVKKTQAPPDDKPFKSDEAALVANNAPVKSAPVASTPGLSTS
AGPKALSKAKPSYPARALALGIEGQVKVQYDIDESGRVTNVRVLEATPRNTFEREVKQVMRKWRFEAVAAKNYVTTIVFK
LDGKMEMN
>Mature_248_residues
MQLIKFFSDRRLTWSLIFSIGLHGSVVAALLYVSVEQMKIQPEIEDTPLAVTMVNIAEFAAPQPAAAAPEPVQETPAVPE
ETPPVLEETPPEPEELPEPVPEPVKPKPKPVKKEVKKPEVKKTQAPPDDKPFKSDEAALVANNAPVKSAPVASTPGLSTS
AGPKALSKAKPSYPARALALGIEGQVKVQYDIDESGRVTNVRVLEATPRNTFEREVKQVMRKWRFEAVAAKNYVTTIVFK
LDGKMEMN

Specific function: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requirin

COG id: COG0810

COG function: function code M; Periplasmic protein TonB, links inner and outer membranes

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB family [H]

Homologues:

Organism=Escherichia coli, GI1787505, Length=126, Percent_Identity=46.031746031746, Blast_Score=107, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003538
- InterPro:   IPR006260 [H]

Pfam domain/function: PF03544 TonB [H]

EC number: NA

Molecular weight: Translated: 27110; Mature: 27110

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLIKFFSDRRLTWSLIFSIGLHGSVVAALLYVSVEQMKIQPEIEDTPLAVTMVNIAEFA
CCHHHHHCCCCHHEEHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCEEEEEEHHHHHC
APQPAAAAPEPVQETPAVPEETPPVLEETPPEPEELPEPVPEPVKPKPKPVKKEVKKPEV
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHCCCCC
KKTQAPPDDKPFKSDEAALVANNAPVKSAPVASTPGLSTSAGPKALSKAKPSYPARALAL
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEE
GIEGQVKVQYDIDESGRVTNVRVLEATPRNTFEREVKQVMRKWRFEAVAAKNYVTTIVFK
CCCCEEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEE
LDGKMEMN
ECCCEECC
>Mature Secondary Structure
MQLIKFFSDRRLTWSLIFSIGLHGSVVAALLYVSVEQMKIQPEIEDTPLAVTMVNIAEFA
CCHHHHHCCCCHHEEHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCEEEEEEHHHHHC
APQPAAAAPEPVQETPAVPEETPPVLEETPPEPEELPEPVPEPVKPKPKPVKKEVKKPEV
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHCCCCC
KKTQAPPDDKPFKSDEAALVANNAPVKSAPVASTPGLSTSAGPKALSKAKPSYPARALAL
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEE
GIEGQVKVQYDIDESGRVTNVRVLEATPRNTFEREVKQVMRKWRFEAVAAKNYVTTIVFK
CCCCEEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEE
LDGKMEMN
ECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8384290 [H]