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The map label for this gene is ipk

Identifier: 51596328

GI number: 51596328

Start: 2357985

End: 2358884

Strand: Reverse

Name: ipk

Synonym: YPTB2002

Alternate gene names: 51596328

Gene position: 2358884-2357985 (Counterclockwise)

Preceding gene: 51596329

Following gene: 51596327

Centisome position: 49.72

GC content: 49.33

Gene sequence:

>900_bases
ATGACTACCGCGAATCAACCTATATGTCCGTCACCAGCAAAATGGCCGTCACCGGCAAAATTGAATTTGTTTCTTTATAT
CACCGGGCAACGCGCCGACGGCTATCATCAGTTACAAACGCTGTTTCAATTTCTTGATTATGGTGATCAACTGACGATTG
AACCGCGCGATGACAACCAAATTCGCTTATTAACCCCCATAGCAGGGGTGGAAAATGAGCAAAACCTGATCGTCCGCGCG
GCAAAAATGCTGCAAAAACACCCTGGCAATACCCCCGTGCCACGCGGTGCTGATATCAGCATTGATAAATGTTTACCGAT
GGGCGGTGGATTGGGGGGCGGTTCGTCTAATGCAGCCACAGTCTTGGTGGCACTCAACCTACTGTGGCAATGTGGTTTAA
CTGATGAACAATTAGCCGATCTCGGACTAACATTAGGGGCTGATGTCCCGGTATTTGTTCGGGGCCATGCCGCCTTCGCA
GAGGGTATTGGTGAAAAATTACAGCCAGCAGAGCCTGTAGAGAAGTGGTATTTGGTCATACACCCCGGTGTAAACATCCC
AACACCGATTATTTTTTCTGATCCTGAATTAAAAAGAAATACGCCAATCCGCCCACTGGCGGCGCTTTTAAGCACTCCAT
ACGCAAATGATTGCGAACCGATCGCAAGAAAACGTTTTCGCGAGGTTGAACAGGCTCTTTCATGGCTGTTAGAATACGCC
CCGTCACGCCTTACCGGTACCGGCGCTTGTGTGTTTGCAGAATTCGACACGGAGTCATCGGCCCGGCAGGTGTTAAGTAT
TGCCCCTGAGTGGTTACATGGTTTTGTCGCCCGTGGTGTAAATGTTTCACCACTGCATCGTGTACGCTCAGGGAAAATTG
AAAGCAGTGAGCGCAGATAA

Upstream 100 bases:

>100_bases
TACAACACGCAGGTCACGCCCCCCTTACCCAGCCGCCTGGAGCTGAATCAAGATGGGCAACGGATTAAACTGAAAATGGA
TAGCTGGACGATCAAATAAC

Downstream 100 bases:

>100_bases
CGATTTACAGCGTTATGTAAGGTCGAAGTAATGGCCTCACTGACCTTGGGTTCTGAAAATACCTGTCTCACTTGATTGAA
AGCCGGTTCATAATGCTGTT

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQIRLLTPIAGVENEQNLIVRA
AKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAATVLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFA
EGIGEKLQPAEPVEKWYLVIHPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYA
PSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR

Sequences:

>Translated_299_residues
MTTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQIRLLTPIAGVENEQNLIVRA
AKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAATVLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFA
EGIGEKLQPAEPVEKWYLVIHPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYA
PSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR
>Mature_298_residues
TTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQIRLLTPIAGVENEQNLIVRAA
KMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAATVLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFAE
GIGEKLQPAEPVEKWYLVIHPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYAP
SRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=277, Percent_Identity=76.1732851985559, Blast_Score=418, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 32676; Mature: 32545

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQ
CCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCC
IRLLTPIAGVENEQNLIVRAAKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAAT
EEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHH
VLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFAEGIGEKLQPAEPVEKWYLVI
HHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCEEEEEE
HPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYA
ECCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
PSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR
CCCCCCCCEEEEEECCCCHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQ
CCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCC
IRLLTPIAGVENEQNLIVRAAKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAAT
EEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHH
VLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFAEGIGEKLQPAEPVEKWYLVI
HHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCEEEEEE
HPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYA
ECCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
PSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR
CCCCCCCCEEEEEECCCCHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA