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The map label for this gene is yfiU [H]

Identifier: 51596264

GI number: 51596264

Start: 2278137

End: 2279777

Strand: Direct

Name: yfiU [H]

Synonym: YPTB1938

Alternate gene names: 51596264

Gene position: 2278137-2279777 (Clockwise)

Preceding gene: 51596263

Following gene: 51596265

Centisome position: 48.01

GC content: 52.1

Gene sequence:

>1641_bases
ATGGCAAATCAATCAGTTTCTCGTACAGGTACGGAAGTTAAGGAGTCCTGGGTGCCGATGATTACCATCGCGCTGGCCCA
GATCCTGATGTCATTCAACGTGGCCTCCCTACCTGTTGCGTTGGGCGGGATGGTAAAGAGCTTTAATGTGCCACCAACCA
CTATTGCCACGGCGATAGTCATGTACTCATTGTCGGTTGCAGGCTTTGTGATGTTGGGTGCCAAACTCAACCAACGCTTT
GGGCCATTGATAGTATTCCGCTGTACAGTTCTGTTATTCGGCCTGGCTCAGACCATGATGACATTCAGCCCGAATGTCAC
TGTAATGATCGGTGCGCAGGCACTGAGTGGTCTGGCAGGTGCGGCATTGGTACCGGCACTGGTGGCGTTAATTGCTGAAA
ACTACCGTGGGCCTCAACAGGCCACCGCACTGGGGGCATTAGGTTCTGCTCGCGCAGGGGCGGGTGTTGCTGCGTTCCTG
ATCGGCGGTATTTTGGGAACCCATATCGGCTGGCGTCCAGCGTTCGGTATTTTGATTGTGTTGTCTGTTATCGTTTTTGT
ACTGAGTTTCCGTCTGAAAGCAGATAAAGGCCGCCCAGAAGTGGGTATTGATGTTATCGGTGTCGTTTTAGCTGCATCTG
CGATTATTTTGTTGTCGTTCGGCTTTAATAACCTGAACCGTTGGGGCTTTGGTCTGGTTCGTGACGGCGCGCCGTTTGAC
CTGCTCGGTTTCTCACCAGCGCCGTTTATGATCGTGTTGGGTATCGTCTTGGGTCAGGCATTTGTGGTCTGGACCCGCCG
CCGTCAGGAGCAAGGTAAAACGCCATTACTGGCGCTAGACGTGATTACATCACCCAGTGAGCGGGCGGCGGTATTTGCCA
TGTTTGCGGTGGTTGCGCTGGAAGCCATGCTGAACTTTTCTGTTCCGCTGTATATACAAATCGTGCAGGGCAGTTCGCCG
ATGGCAACAGCTATCGCTATGATGCCGTTTAACCTATCGGTATTCTTCTCTGCGATGCTGATTGTACGTTTCTACAAGAA
ACTGACTCCGCGTAAAATTGGTCGTTACGGTTTCATCACTTGTACTTTGGCGCTGTTGTGGCTGGCATTCGTGGTACGTA
ATAACTGGAGTGAGTGGTCGGTCTTGATTGGTTTGGTGGTGTTCGGTATCGGACAAGGCTCACTCGTCACCTTGCTGTTC
AACGTACTGGTCAGTGCATCACCAAAAGAATTGGCAGGCGATGTGGGTTCTTTACGTGGTACGACCAACAATCTGGCAAG
CGCCATCGGTACAGCGGTTGCAGGTGCCTTGCTGGTGGGCTTGTTAAGTGCCAACGTGATGCGCGGTGTCGCTGAAACGC
CGATTCTGACGGATGAGATCCAAGCTCAGGTCAATATGGATAGCATCAACTTCGTCAGTAATGATCGCCTGAACAGTGTA
TTGGCTCAAACCTCCGCGACCCCAGAACAGGTTGCCGAAGCGGTGCGGGTGAATGAAGAAGCACGGTTACGTGCGCTGAA
ATTCGGTTTGCTGGTTATGGCGCTGCTATCGCTGTTGGCTATCTTCCCTGCTGGCCGCTTACCTGACTATCTGCCGGGTG
AACTGCCTGCTGATAATCTGGATAAAAAAGCCAGCAAGTAA

Upstream 100 bases:

>100_bases
ATCGATGTTGTTCTGAAAGCCAGGCGGTCTTGGCAATCAGGTTATATCGAAAATTAAGTTGTTCTAAAAACAAAAAATAG
ATCAAAAGGATAGAAAATTT

Downstream 100 bases:

>100_bases
GTTGCTGGAGGTTATTGACAAAGTGCCCGCGACGGAGAGAACAGGCAGATCGTAAAGACGCCGTAAATACATCCATGTAG
GCTCGAGCCGCGCCATCCTT

Product: MFS superfamily multidrug efflux transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MANQSVSRTGTEVKESWVPMITIALAQILMSFNVASLPVALGGMVKSFNVPPTTIATAIVMYSLSVAGFVMLGAKLNQRF
GPLIVFRCTVLLFGLAQTMMTFSPNVTVMIGAQALSGLAGAALVPALVALIAENYRGPQQATALGALGSARAGAGVAAFL
IGGILGTHIGWRPAFGILIVLSVIVFVLSFRLKADKGRPEVGIDVIGVVLAASAIILLSFGFNNLNRWGFGLVRDGAPFD
LLGFSPAPFMIVLGIVLGQAFVVWTRRRQEQGKTPLLALDVITSPSERAAVFAMFAVVALEAMLNFSVPLYIQIVQGSSP
MATAIAMMPFNLSVFFSAMLIVRFYKKLTPRKIGRYGFITCTLALLWLAFVVRNNWSEWSVLIGLVVFGIGQGSLVTLLF
NVLVSASPKELAGDVGSLRGTTNNLASAIGTAVAGALLVGLLSANVMRGVAETPILTDEIQAQVNMDSINFVSNDRLNSV
LAQTSATPEQVAEAVRVNEEARLRALKFGLLVMALLSLLAIFPAGRLPDYLPGELPADNLDKKASK

Sequences:

>Translated_546_residues
MANQSVSRTGTEVKESWVPMITIALAQILMSFNVASLPVALGGMVKSFNVPPTTIATAIVMYSLSVAGFVMLGAKLNQRF
GPLIVFRCTVLLFGLAQTMMTFSPNVTVMIGAQALSGLAGAALVPALVALIAENYRGPQQATALGALGSARAGAGVAAFL
IGGILGTHIGWRPAFGILIVLSVIVFVLSFRLKADKGRPEVGIDVIGVVLAASAIILLSFGFNNLNRWGFGLVRDGAPFD
LLGFSPAPFMIVLGIVLGQAFVVWTRRRQEQGKTPLLALDVITSPSERAAVFAMFAVVALEAMLNFSVPLYIQIVQGSSP
MATAIAMMPFNLSVFFSAMLIVRFYKKLTPRKIGRYGFITCTLALLWLAFVVRNNWSEWSVLIGLVVFGIGQGSLVTLLF
NVLVSASPKELAGDVGSLRGTTNNLASAIGTAVAGALLVGLLSANVMRGVAETPILTDEIQAQVNMDSINFVSNDRLNSV
LAQTSATPEQVAEAVRVNEEARLRALKFGLLVMALLSLLAIFPAGRLPDYLPGELPADNLDKKASK
>Mature_545_residues
ANQSVSRTGTEVKESWVPMITIALAQILMSFNVASLPVALGGMVKSFNVPPTTIATAIVMYSLSVAGFVMLGAKLNQRFG
PLIVFRCTVLLFGLAQTMMTFSPNVTVMIGAQALSGLAGAALVPALVALIAENYRGPQQATALGALGSARAGAGVAAFLI
GGILGTHIGWRPAFGILIVLSVIVFVLSFRLKADKGRPEVGIDVIGVVLAASAIILLSFGFNNLNRWGFGLVRDGAPFDL
LGFSPAPFMIVLGIVLGQAFVVWTRRRQEQGKTPLLALDVITSPSERAAVFAMFAVVALEAMLNFSVPLYIQIVQGSSPM
ATAIAMMPFNLSVFFSAMLIVRFYKKLTPRKIGRYGFITCTLALLWLAFVVRNNWSEWSVLIGLVVFGIGQGSLVTLLFN
VLVSASPKELAGDVGSLRGTTNNLASAIGTAVAGALLVGLLSANVMRGVAETPILTDEIQAQVNMDSINFVSNDRLNSVL
AQTSATPEQVAEAVRVNEEARLRALKFGLLVMALLSLLAIFPAGRLPDYLPGELPADNLDKKASK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 57815; Mature: 57684

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANQSVSRTGTEVKESWVPMITIALAQILMSFNVASLPVALGGMVKSFNVPPTTIATAIV
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
MYSLSVAGFVMLGAKLNQRFGPLIVFRCTVLLFGLAQTMMTFSPNVTVMIGAQALSGLAG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHCCHHH
AALVPALVALIAENYRGPQQATALGALGSARAGAGVAAFLIGGILGTHIGWRPAFGILIV
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
LSVIVFVLSFRLKADKGRPEVGIDVIGVVLAASAIILLSFGFNNLNRWGFGLVRDGAPFD
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCC
LLGFSPAPFMIVLGIVLGQAFVVWTRRRQEQGKTPLLALDVITSPSERAAVFAMFAVVAL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
EAMLNFSVPLYIQIVQGSSPMATAIAMMPFNLSVFFSAMLIVRFYKKLTPRKIGRYGFIT
HHHHHCCCCEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHCCHHHHH
CTLALLWLAFVVRNNWSEWSVLIGLVVFGIGQGSLVTLLFNVLVSASPKELAGDVGSLRG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCHHHCCC
TTNNLASAIGTAVAGALLVGLLSANVMRGVAETPILTDEIQAQVNMDSINFVSNDRLNSV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHH
LAQTSATPEQVAEAVRVNEEARLRALKFGLLVMALLSLLAIFPAGRLPDYLPGELPADNL
HHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DKKASK
CCCCCC
>Mature Secondary Structure 
ANQSVSRTGTEVKESWVPMITIALAQILMSFNVASLPVALGGMVKSFNVPPTTIATAIV
CCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
MYSLSVAGFVMLGAKLNQRFGPLIVFRCTVLLFGLAQTMMTFSPNVTVMIGAQALSGLAG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHCCHHH
AALVPALVALIAENYRGPQQATALGALGSARAGAGVAAFLIGGILGTHIGWRPAFGILIV
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
LSVIVFVLSFRLKADKGRPEVGIDVIGVVLAASAIILLSFGFNNLNRWGFGLVRDGAPFD
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCC
LLGFSPAPFMIVLGIVLGQAFVVWTRRRQEQGKTPLLALDVITSPSERAAVFAMFAVVAL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
EAMLNFSVPLYIQIVQGSSPMATAIAMMPFNLSVFFSAMLIVRFYKKLTPRKIGRYGFIT
HHHHHCCCCEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHCCHHHHH
CTLALLWLAFVVRNNWSEWSVLIGLVVFGIGQGSLVTLLFNVLVSASPKELAGDVGSLRG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCHHHCCC
TTNNLASAIGTAVAGALLVGLLSANVMRGVAETPILTDEIQAQVNMDSINFVSNDRLNSV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHH
LAQTSATPEQVAEAVRVNEEARLRALKFGLLVMALLSLLAIFPAGRLPDYLPGELPADNL
HHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DKKASK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]