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The map label for this gene is bvgS [H]

Identifier: 51596248

GI number: 51596248

Start: 2256327

End: 2260355

Strand: Reverse

Name: bvgS [H]

Synonym: YPTB1922

Alternate gene names: 51596248

Gene position: 2260355-2256327 (Counterclockwise)

Preceding gene: 51596249

Following gene: 51596247

Centisome position: 47.64

GC content: 46.76

Gene sequence:

>4029_bases
ATGCACACACCCATAATTTGGTGTAATTCACTGCGTACTACATTTCTTTTACGTGCCCGATTTCTTTTACGTGCCCGGTT
TTCTTTACGTAGCTGGTTTTTTTTGCGTACCGTACTCTGCTGCCTGCTACTGATTAGCGGGCAGCTTCATGCTTCTCTAA
TGACGGGTCGTCAAGGATGTGATACCGGGCAGCCCTTGACGATCCACAGTATCGCCAACAGCTACAATGACGATTTGTTG
CTCACCCCTGCCACCGATACCCGCCAATCAAGCCGACGCACAGTTAAAGTCGGCGTGGTCATGGATGCGAATACCCCTTT
TGTGGTTAACCGCGATGATAATGCCATTGAAGGAATTGTTGCGGATTATCTGAAGATAATCAGCGATGCCAGCCAACTCT
CTTTTCAGATGATTGGTTACTGCGATTACGGGCTGGTATTAAATGCGTTGGAGAATGGCCAAATTGATTTAATGGCAGGC
ACTCCCATGTTGGCCCAGCCGGGGCTAATCGCTTCTCATGCTTTCTTCACAAACCGGCATGTTGAAGTTCGTAGCAAAAA
TTGGGATCCTACCAAACGTACACATCCAGAAACCGTGGCTATTGTGAATAATGAGCCACTGTCTCCCGAGTTTCTCTTTA
ATTATCACGCAGACCGAATTGTTGCTTACCCCAACCAATTGCAAGGATTGCTCGCTGTTGCCTATGGTAATGCTGATGTC
TTTGTGGCTAATGCAACATCAGCAAATTATTTAATTGACCAACTACAATTGCTGACGCTGCAAATTCGAAATTTTGCACC
TTATCACCCTGCCCCTTATTCATTCCTGGCCAGGGAAAGTAATCAGAAGCTGATCGATTACCTCAATCAAATTCTGGAAT
TATTACCCACCCGCGCTACTGGCGATATTCAACAGCGCTGGTTTGGTAGCAAGCATCACTACAATATCGATGCTAAATTG
CTGCTGACAGAACAAGAAATCAGTTGGATCCAACATCATCCGGTGGTGACCTATATTGCCCCACTCGATCTAGCACCGTT
GATTTTCCGTGACCGCCGGACCGGAGAAATGGCCGGTTTTTCTGTCGATCTTATCGATATCATTGCCCGTCGTACCGGGA
TTAAGTTTGATCCGGTCTATACCAAAGATACCGGAGAAGGTGTTCGCAGTTTTAAAGCTGGCAAGGTCGATTTATTACCG
ATTGTTGCTGTGCGCAATGGTCAGTATGGCAACAATCTCTACTCCTCCTCAATAGCCCAATCGCTATGGGGGATTATGAC
CCGTGAAGACCGCATGGATATCAATAACGTCGGTGATCTGGCAGGAAAGCGGGTTGGGATCCAGGCGGGCAGTGCCTCCA
GCAGCATTATTGGTAACCCACTGCTAGCACAGAGAATTACTTTTGTTGAAGCCCCAGACACCATGACGTTAGTACGCTGG
CTACAGCAAGGGAAAGTTGACGCCGTCGTTAAAAACATGATGACCGCCAACTACTTGTCAGCACAAAATTTCAGCCCAAA
TATCAAAACCGTGGCGGTAGCCGGTGAAGAGCCATTAATGATGGCATTTGCCATACGCCCTGACCTGCCAGAATTAAAAA
CTATTATTGATAAAGTCATTGAATCTATCCCACCGGAAGAGTTCGATAACCTAACCAGTGAGTGGAGTACTTTTAAACCA
AAACCTATCAGTTTTGATGAAAGCTCACTGGATAACGAACTTCTGATGATCGCGCTGAAAATAAGCTCGGGGCTGCTCTT
GGTCTTCGGCTTGTATCTCTGCTATTTGGTCTTCAATAAACGCCGTCAGGCCAAATTGTTGCATGCCCGTTTATTGCAGC
AAGAGTCCATTATCAATGCATTACCGTTTGCTGTATTCATTCGCACCGCGAGTGGTGAGTTAGCCGTTTATAACAGCCAC
TTTGCTGATGTGCACAGCGATAAGCTTTACGACATGCTCAATCAAACTCATGAGCCAGCACATTGGCCAATGACCAGCCC
GCTTGATCGTGAAATTGATAAATATTGTCGCAGTGTATTACTCAATAGAAAACCACAACTTGTTGACTTATCTGTAGAAA
TAAAGGGTGAGATACGGGATATTTTTCTGTGGATTATTCCTCTTAATAATGCGGAACAGGGGTTGTTGGGCGGCTGGCTA
GACATCAGTCAGCGCAAAACTGTCGAACGGCAATTGGAAGCGGCCCGTGTTGAAGCCGAAAGTGCTAACCGGACCAAGAG
TACTTTCCTCGCAACCATCAGCCATGAGTTGCGTACCCCGATGTACGCGATTATGGGGTTATTGGAACTGGAAATTCGCA
GTAACCGGCCTGTCGAAAAAGATACGCTAGTGACCGTGTCTAAATCTGCTCAATCACTGATGCTCCTGCTTGATGACATC
ATCGATTCGGCTAAAATTGAAGCTGGTCAACTGAGTATTCATCCAACTGCGGTCGACTTCCATCAGGAAATGGAGCGGAT
GTTTACGCTCTATCAACCTATTGCCAATGAGCGCGGGTTACGTTTCTCCGGTTGGTTGGATGACCATATCCCACCGTTAT
TGATGGCCGATATGCTGCGAGTACGTCAGGTGATGGGCAATTTGCTCGGTAATGCGTTGAAGTTCACTGAGCAAGGCAGT
GTTTCTGTTGATATTACTTGGGAACCAAGCGACGAACAGCATGGTGTGATGAATATTGATATCACCGATACCGGTATTGG
TATCTCCCCTGCCGCACAGGCGACCTTATTTCAGCCATTCAGCCAAGCCAATGAGGGTAAATCGCCACGCTTCGGTGGGT
CCGGTTTAGGTTTATGGATTTGCCACCAATTGATTCATAAAATGGGGGGTAAAATAGCGCTGGAAAGCCAATTAGGCAAA
GGAACCAGCCTGCTTATCACACTACCACTGAATATTGCGACTGCGGATGATTTAGCCCAAGATGCGGCGATAACACATGT
TGATGATGAACGGCTGAATCAACTGAGAAACCTGCGAATTCTGGTCGTTGATGATTTACCCGCAAACCGCCAGTTACTTC
AACAACAGTTGGCCTTTATTGGTATCGAGCAGGTAGTCACCGCCGAAAATGGGGCGAAAGCCTGCCAAATATTGCAGCAC
AATAACTTTGATGTGGTAATAACCGATTGCAGTATGCCGGTGATGGATGGATATGAACTCGCAGCACATATTCGCCAGGA
TCCAGCCTTAAAAGACCTCATCGTGATTGGGTGTACTGCTGACGCCCGCGAAGAAAGTGCAGCACGCTGCATTGATGCGG
GAATGAATGCCTGCATGATCAAACCCGTGGCCATCGATACTTTACAGGCGACCTTACTGCGCAAAGATATCGTGAGCCAG
ATTGCGAATACCAATCATAGCCACAGCACAGAAGATAATGACCGCGGTGGCAATCAACACAATTTGAGTGAAAAAGATAC
AGCCCAGCAAGAAAATGCTCCAGCTATCCACAGCACAACCATCACCTCTTCGGTTAATAGGCTAGCTGCGGCACAGAATA
AGCTGCGGACATTATCGGGGGGGAACCCTGCGGTAGAATTGCAATTATTGCAATCATTGCTGGAAAGCAATTTGCAGGAT
GCTGTCACATTGACGCAACTTTATCGCCAACTCTGTGTAGAAGACGAAGACGTTGTGGAAACTGTAGATACTGCGGAAAC
TGTAGATACTGCGGAAACTGCGGATACTGTGGAAGATGGGGAGACCAGAGGACCGGGTAGCACGGTAGGTCGTCATAGCA
CGACAGGCAGTGACCACATCCCTCACGCAGATATTTATAAACAGATGGCAAGCCTGGTACACCGCATTAAAGGCAGCGTA
CAACTGATTGATGCTCAAGAACTGGTCGCAAGTTGCGTGAAATTTGAATCTCAATTACATGCACAGAATAAACAAGCAGC
GATGACACATGGCGCTGATTGTCTGGCATTGTTTATTGAATCTAATCAGTTATTAGTCACATTAATTTCTCAATATCCTA
AAGCCGCTACTGAAGACTCGCCACAATAA

Upstream 100 bases:

>100_bases
ATTGCCGATGAAATGTTTATCAGCAATAAAACTGTGAGTACCTATAAAACCCGAATTTTGACCAAATTGGGACTCAGTTC
TGTCATTGAATTAGCCGATT

Downstream 100 bases:

>100_bases
AGGTTATAGCGTAATTCCCCTATTAAAAGCGCCAGTCTTCTTGGCGTTTTTTTTTGATTCAGCGATGAGGATAACCGCCT
ATATAAAAAGCTAATTCATC

Product: two-component sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1342; Mature: 1342

Protein sequence:

>1342_residues
MHTPIIWCNSLRTTFLLRARFLLRARFSLRSWFFLRTVLCCLLLISGQLHASLMTGRQGCDTGQPLTIHSIANSYNDDLL
LTPATDTRQSSRRTVKVGVVMDANTPFVVNRDDNAIEGIVADYLKIISDASQLSFQMIGYCDYGLVLNALENGQIDLMAG
TPMLAQPGLIASHAFFTNRHVEVRSKNWDPTKRTHPETVAIVNNEPLSPEFLFNYHADRIVAYPNQLQGLLAVAYGNADV
FVANATSANYLIDQLQLLTLQIRNFAPYHPAPYSFLARESNQKLIDYLNQILELLPTRATGDIQQRWFGSKHHYNIDAKL
LLTEQEISWIQHHPVVTYIAPLDLAPLIFRDRRTGEMAGFSVDLIDIIARRTGIKFDPVYTKDTGEGVRSFKAGKVDLLP
IVAVRNGQYGNNLYSSSIAQSLWGIMTREDRMDINNVGDLAGKRVGIQAGSASSSIIGNPLLAQRITFVEAPDTMTLVRW
LQQGKVDAVVKNMMTANYLSAQNFSPNIKTVAVAGEEPLMMAFAIRPDLPELKTIIDKVIESIPPEEFDNLTSEWSTFKP
KPISFDESSLDNELLMIALKISSGLLLVFGLYLCYLVFNKRRQAKLLHARLLQQESIINALPFAVFIRTASGELAVYNSH
FADVHSDKLYDMLNQTHEPAHWPMTSPLDREIDKYCRSVLLNRKPQLVDLSVEIKGEIRDIFLWIIPLNNAEQGLLGGWL
DISQRKTVERQLEAARVEAESANRTKSTFLATISHELRTPMYAIMGLLELEIRSNRPVEKDTLVTVSKSAQSLMLLLDDI
IDSAKIEAGQLSIHPTAVDFHQEMERMFTLYQPIANERGLRFSGWLDDHIPPLLMADMLRVRQVMGNLLGNALKFTEQGS
VSVDITWEPSDEQHGVMNIDITDTGIGISPAAQATLFQPFSQANEGKSPRFGGSGLGLWICHQLIHKMGGKIALESQLGK
GTSLLITLPLNIATADDLAQDAAITHVDDERLNQLRNLRILVVDDLPANRQLLQQQLAFIGIEQVVTAENGAKACQILQH
NNFDVVITDCSMPVMDGYELAAHIRQDPALKDLIVIGCTADAREESAARCIDAGMNACMIKPVAIDTLQATLLRKDIVSQ
IANTNHSHSTEDNDRGGNQHNLSEKDTAQQENAPAIHSTTITSSVNRLAAAQNKLRTLSGGNPAVELQLLQSLLESNLQD
AVTLTQLYRQLCVEDEDVVETVDTAETVDTAETADTVEDGETRGPGSTVGRHSTTGSDHIPHADIYKQMASLVHRIKGSV
QLIDAQELVASCVKFESQLHAQNKQAAMTHGADCLALFIESNQLLVTLISQYPKAATEDSPQ

Sequences:

>Translated_1342_residues
MHTPIIWCNSLRTTFLLRARFLLRARFSLRSWFFLRTVLCCLLLISGQLHASLMTGRQGCDTGQPLTIHSIANSYNDDLL
LTPATDTRQSSRRTVKVGVVMDANTPFVVNRDDNAIEGIVADYLKIISDASQLSFQMIGYCDYGLVLNALENGQIDLMAG
TPMLAQPGLIASHAFFTNRHVEVRSKNWDPTKRTHPETVAIVNNEPLSPEFLFNYHADRIVAYPNQLQGLLAVAYGNADV
FVANATSANYLIDQLQLLTLQIRNFAPYHPAPYSFLARESNQKLIDYLNQILELLPTRATGDIQQRWFGSKHHYNIDAKL
LLTEQEISWIQHHPVVTYIAPLDLAPLIFRDRRTGEMAGFSVDLIDIIARRTGIKFDPVYTKDTGEGVRSFKAGKVDLLP
IVAVRNGQYGNNLYSSSIAQSLWGIMTREDRMDINNVGDLAGKRVGIQAGSASSSIIGNPLLAQRITFVEAPDTMTLVRW
LQQGKVDAVVKNMMTANYLSAQNFSPNIKTVAVAGEEPLMMAFAIRPDLPELKTIIDKVIESIPPEEFDNLTSEWSTFKP
KPISFDESSLDNELLMIALKISSGLLLVFGLYLCYLVFNKRRQAKLLHARLLQQESIINALPFAVFIRTASGELAVYNSH
FADVHSDKLYDMLNQTHEPAHWPMTSPLDREIDKYCRSVLLNRKPQLVDLSVEIKGEIRDIFLWIIPLNNAEQGLLGGWL
DISQRKTVERQLEAARVEAESANRTKSTFLATISHELRTPMYAIMGLLELEIRSNRPVEKDTLVTVSKSAQSLMLLLDDI
IDSAKIEAGQLSIHPTAVDFHQEMERMFTLYQPIANERGLRFSGWLDDHIPPLLMADMLRVRQVMGNLLGNALKFTEQGS
VSVDITWEPSDEQHGVMNIDITDTGIGISPAAQATLFQPFSQANEGKSPRFGGSGLGLWICHQLIHKMGGKIALESQLGK
GTSLLITLPLNIATADDLAQDAAITHVDDERLNQLRNLRILVVDDLPANRQLLQQQLAFIGIEQVVTAENGAKACQILQH
NNFDVVITDCSMPVMDGYELAAHIRQDPALKDLIVIGCTADAREESAARCIDAGMNACMIKPVAIDTLQATLLRKDIVSQ
IANTNHSHSTEDNDRGGNQHNLSEKDTAQQENAPAIHSTTITSSVNRLAAAQNKLRTLSGGNPAVELQLLQSLLESNLQD
AVTLTQLYRQLCVEDEDVVETVDTAETVDTAETADTVEDGETRGPGSTVGRHSTTGSDHIPHADIYKQMASLVHRIKGSV
QLIDAQELVASCVKFESQLHAQNKQAAMTHGADCLALFIESNQLLVTLISQYPKAATEDSPQ
>Mature_1342_residues
MHTPIIWCNSLRTTFLLRARFLLRARFSLRSWFFLRTVLCCLLLISGQLHASLMTGRQGCDTGQPLTIHSIANSYNDDLL
LTPATDTRQSSRRTVKVGVVMDANTPFVVNRDDNAIEGIVADYLKIISDASQLSFQMIGYCDYGLVLNALENGQIDLMAG
TPMLAQPGLIASHAFFTNRHVEVRSKNWDPTKRTHPETVAIVNNEPLSPEFLFNYHADRIVAYPNQLQGLLAVAYGNADV
FVANATSANYLIDQLQLLTLQIRNFAPYHPAPYSFLARESNQKLIDYLNQILELLPTRATGDIQQRWFGSKHHYNIDAKL
LLTEQEISWIQHHPVVTYIAPLDLAPLIFRDRRTGEMAGFSVDLIDIIARRTGIKFDPVYTKDTGEGVRSFKAGKVDLLP
IVAVRNGQYGNNLYSSSIAQSLWGIMTREDRMDINNVGDLAGKRVGIQAGSASSSIIGNPLLAQRITFVEAPDTMTLVRW
LQQGKVDAVVKNMMTANYLSAQNFSPNIKTVAVAGEEPLMMAFAIRPDLPELKTIIDKVIESIPPEEFDNLTSEWSTFKP
KPISFDESSLDNELLMIALKISSGLLLVFGLYLCYLVFNKRRQAKLLHARLLQQESIINALPFAVFIRTASGELAVYNSH
FADVHSDKLYDMLNQTHEPAHWPMTSPLDREIDKYCRSVLLNRKPQLVDLSVEIKGEIRDIFLWIIPLNNAEQGLLGGWL
DISQRKTVERQLEAARVEAESANRTKSTFLATISHELRTPMYAIMGLLELEIRSNRPVEKDTLVTVSKSAQSLMLLLDDI
IDSAKIEAGQLSIHPTAVDFHQEMERMFTLYQPIANERGLRFSGWLDDHIPPLLMADMLRVRQVMGNLLGNALKFTEQGS
VSVDITWEPSDEQHGVMNIDITDTGIGISPAAQATLFQPFSQANEGKSPRFGGSGLGLWICHQLIHKMGGKIALESQLGK
GTSLLITLPLNIATADDLAQDAAITHVDDERLNQLRNLRILVVDDLPANRQLLQQQLAFIGIEQVVTAENGAKACQILQH
NNFDVVITDCSMPVMDGYELAAHIRQDPALKDLIVIGCTADAREESAARCIDAGMNACMIKPVAIDTLQATLLRKDIVSQ
IANTNHSHSTEDNDRGGNQHNLSEKDTAQQENAPAIHSTTITSSVNRLAAAQNKLRTLSGGNPAVELQLLQSLLESNLQD
AVTLTQLYRQLCVEDEDVVETVDTAETVDTAETADTVEDGETRGPGSTVGRHSTTGSDHIPHADIYKQMASLVHRIKGSV
QLIDAQELVASCVKFESQLHAQNKQAAMTHGADCLALFIESNQLLVTLISQYPKAATEDSPQ

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=1074, Percent_Identity=26.0707635009311, Blast_Score=332, Evalue=9e-92,
Organism=Escherichia coli, GI87081816, Length=380, Percent_Identity=32.6315789473684, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=37.3015873015873, Blast_Score=166, Evalue=1e-41,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=34.1176470588235, Blast_Score=166, Evalue=1e-41,
Organism=Escherichia coli, GI48994928, Length=426, Percent_Identity=29.3427230046948, Blast_Score=164, Evalue=4e-41,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=29.3103448275862, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=326, Percent_Identity=25.7668711656442, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=27.5109170305677, Blast_Score=80, Evalue=8e-16,
Organism=Escherichia coli, GI1786600, Length=392, Percent_Identity=25.5102040816327, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=29.8245614035088, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1786912, Length=257, Percent_Identity=25.2918287937743, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI1788191, Length=117, Percent_Identity=36.7521367521368, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=284, Percent_Identity=23.5915492957746, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=238, Percent_Identity=26.890756302521, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=26.8, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=76, Percent_Identity=47.3684210526316, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 148757; Mature: 148757

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTPIIWCNSLRTTFLLRARFLLRARFSLRSWFFLRTVLCCLLLISGQLHASLMTGRQGC
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
DTGQPLTIHSIANSYNDDLLLTPATDTRQSSRRTVKVGVVMDANTPFVVNRDDNAIEGIV
CCCCCEEEEEHHCCCCCCEEEECCCCCCCCCCCEEEEEEEEECCCCEEEECCCCHHHHHH
ADYLKIISDASQLSFQMIGYCDYGLVLNALENGQIDLMAGTPMLAQPGLIASHAFFTNRH
HHHHHHHHCHHHHCEEEEEEECHHHHHHHHCCCCEEEEECCCCCCCCCCEEHHHEEECCE
VEVRSKNWDPTKRTHPETVAIVNNEPLSPEFLFNYHADRIVAYPNQLQGLLAVAYGNADV
EEEECCCCCCCCCCCCCEEEEECCCCCCCHHHEEECCCEEEECCHHHCEEEEEEECCCEE
FVANATSANYLIDQLQLLTLQIRNFAPYHPAPYSFLARESNQKLIDYLNQILELLPTRAT
EEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCC
GDIQQRWFGSKHHYNIDAKLLLTEQEISWIQHHPVVTYIAPLDLAPLIFRDRRTGEMAGF
CCHHHHHCCCCCEECCCEEEEEEHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCCCCC
SVDLIDIIARRTGIKFDPVYTKDTGEGVRSFKAGKVDLLPIVAVRNGQYGNNLYSSSIAQ
CHHHHHHHHHHCCCEECCEEECCCCHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHHHHH
SLWGIMTREDRMDINNVGDLAGKRVGIQAGSASSSIIGNPLLAQRITFVEAPDTMTLVRW
HHHHHHCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCHHHHHEEEEECCCHHHHHHH
LQQGKVDAVVKNMMTANYLSAQNFSPNIKTVAVAGEEPLMMAFAIRPDLPELKTIIDKVI
HHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHH
ESIPPEEFDNLTSEWSTFKPKPISFDESSLDNELLMIALKISSGLLLVFGLYLCYLVFNK
HHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCC
RRQAKLLHARLLQQESIINALPFAVFIRTASGELAVYNSHFADVHSDKLYDMLNQTHEPA
CHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCC
HWPMTSPLDREIDKYCRSVLLNRKPQLVDLSVEIKGEIRDIFLWIIPLNNAEQGLLGGWL
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEEEEECCCCCCCCCCCHH
DISQRKTVERQLEAARVEAESANRTKSTFLATISHELRTPMYAIMGLLELEIRSNRPVEK
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCC
DTLVTVSKSAQSLMLLLDDIIDSAKIEAGQLSIHPTAVDFHQEMERMFTLYQPIANERGL
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCC
RFSGWLDDHIPPLLMADMLRVRQVMGNLLGNALKFTEQGSVSVDITWEPSDEQHGVMNID
EEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCCCCCEEEEE
ITDTGIGISPAAQATLFQPFSQANEGKSPRFGGSGLGLWICHQLIHKMGGKIALESQLGK
EECCCCCCCCCCHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCC
GTSLLITLPLNIATADDLAQDAAITHVDDERLNQLRNLRILVVDDLPANRQLLQQQLAFI
CCEEEEEEECCCCCHHHHHHCCCEEECCHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHH
GIEQVVTAENGAKACQILQHNNFDVVITDCSMPVMDGYELAAHIRQDPALKDLIVIGCTA
HHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEEECCC
DAREESAARCIDAGMNACMIKPVAIDTLQATLLRKDIVSQIANTNHSHSTEDNDRGGNQH
CCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NLSEKDTAQQENAPAIHSTTITSSVNRLAAAQNKLRTLSGGNPAVELQLLQSLLESNLQD
CCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCHHH
AVTLTQLYRQLCVEDEDVVETVDTAETVDTAETADTVEDGETRGPGSTVGRHSTTGSDHI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
PHADIYKQMASLVHRIKGSVQLIDAQELVASCVKFESQLHAQNKQAAMTHGADCLALFIE
CCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEE
SNQLLVTLISQYPKAATEDSPQ
CCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MHTPIIWCNSLRTTFLLRARFLLRARFSLRSWFFLRTVLCCLLLISGQLHASLMTGRQGC
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
DTGQPLTIHSIANSYNDDLLLTPATDTRQSSRRTVKVGVVMDANTPFVVNRDDNAIEGIV
CCCCCEEEEEHHCCCCCCEEEECCCCCCCCCCCEEEEEEEEECCCCEEEECCCCHHHHHH
ADYLKIISDASQLSFQMIGYCDYGLVLNALENGQIDLMAGTPMLAQPGLIASHAFFTNRH
HHHHHHHHCHHHHCEEEEEEECHHHHHHHHCCCCEEEEECCCCCCCCCCEEHHHEEECCE
VEVRSKNWDPTKRTHPETVAIVNNEPLSPEFLFNYHADRIVAYPNQLQGLLAVAYGNADV
EEEECCCCCCCCCCCCCEEEEECCCCCCCHHHEEECCCEEEECCHHHCEEEEEEECCCEE
FVANATSANYLIDQLQLLTLQIRNFAPYHPAPYSFLARESNQKLIDYLNQILELLPTRAT
EEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCC
GDIQQRWFGSKHHYNIDAKLLLTEQEISWIQHHPVVTYIAPLDLAPLIFRDRRTGEMAGF
CCHHHHHCCCCCEECCCEEEEEEHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCCCCC
SVDLIDIIARRTGIKFDPVYTKDTGEGVRSFKAGKVDLLPIVAVRNGQYGNNLYSSSIAQ
CHHHHHHHHHHCCCEECCEEECCCCHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHHHHH
SLWGIMTREDRMDINNVGDLAGKRVGIQAGSASSSIIGNPLLAQRITFVEAPDTMTLVRW
HHHHHHCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCHHHHHEEEEECCCHHHHHHH
LQQGKVDAVVKNMMTANYLSAQNFSPNIKTVAVAGEEPLMMAFAIRPDLPELKTIIDKVI
HHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHH
ESIPPEEFDNLTSEWSTFKPKPISFDESSLDNELLMIALKISSGLLLVFGLYLCYLVFNK
HHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCC
RRQAKLLHARLLQQESIINALPFAVFIRTASGELAVYNSHFADVHSDKLYDMLNQTHEPA
CHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCC
HWPMTSPLDREIDKYCRSVLLNRKPQLVDLSVEIKGEIRDIFLWIIPLNNAEQGLLGGWL
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEEEEECCCCCCCCCCCHH
DISQRKTVERQLEAARVEAESANRTKSTFLATISHELRTPMYAIMGLLELEIRSNRPVEK
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCC
DTLVTVSKSAQSLMLLLDDIIDSAKIEAGQLSIHPTAVDFHQEMERMFTLYQPIANERGL
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCC
RFSGWLDDHIPPLLMADMLRVRQVMGNLLGNALKFTEQGSVSVDITWEPSDEQHGVMNID
EEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCCCCCEEEEE
ITDTGIGISPAAQATLFQPFSQANEGKSPRFGGSGLGLWICHQLIHKMGGKIALESQLGK
EECCCCCCCCCCHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCC
GTSLLITLPLNIATADDLAQDAAITHVDDERLNQLRNLRILVVDDLPANRQLLQQQLAFI
CCEEEEEEECCCCCHHHHHHCCCEEECCHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHH
GIEQVVTAENGAKACQILQHNNFDVVITDCSMPVMDGYELAAHIRQDPALKDLIVIGCTA
HHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEEECCC
DAREESAARCIDAGMNACMIKPVAIDTLQATLLRKDIVSQIANTNHSHSTEDNDRGGNQH
CCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NLSEKDTAQQENAPAIHSTTITSSVNRLAAAQNKLRTLSGGNPAVELQLLQSLLESNLQD
CCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCHHH
AVTLTQLYRQLCVEDEDVVETVDTAETVDTAETADTVEDGETRGPGSTVGRHSTTGSDHI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
PHADIYKQMASLVHRIKGSVQLIDAQELVASCVKFESQLHAQNKQAAMTHGADCLALFIE
CCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEE
SNQLLVTLISQYPKAATEDSPQ
CCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]