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The map label for this gene is lysA

Identifier: 51596221

GI number: 51596221

Start: 2230727

End: 2231893

Strand: Direct

Name: lysA

Synonym: YPTB1889

Alternate gene names: 51596221

Gene position: 2230727-2231893 (Clockwise)

Preceding gene: 51596220

Following gene: 51596222

Centisome position: 47.02

GC content: 40.1

Gene sequence:

>1167_bases
ATGACACTGTCGACGATAGATTTATTTAATCTCAGTGAAAACGAAGATTATGTTTATATTCTAGATCTTGACGCGATGAC
TCAGTTCGTTCGCGAATTTAGAGGGATATGGGATAAACAATTCCCTCACGTAATTTTTGCCTATTCGTTTAAAAGTAATA
ATATTGCTTCCGTCACACAACTGATGTTTAGAGAGGGTTTTTCTGCTGAAGTTGTCTCTCTGCATGAATTAAAGCTTGCG
ATTAATGATGGATTTTTTGGAACCAATATTTTTTTTGATGGCCCGGTTAAATTGGATAACGAGATTGAGTTTGCGCTATC
AAATAACGTTAATATTCAGTGTGATAATATAACTGAAATAGAAAGAGTATTAGCGCTTGCTGCTAACACTAATGCTGAAC
CTCACATTTCATTACGCCTAAGTTCCGACTATCGTGGCCAAGGACTATCGCGCTTCGGTATGGATAAAGACGAGTGGAAT
GAGGCCATCGCTTTACTCACTACTCATGGCATTTTGTGCAACGGGATTCATGTCCATTCTGGATCTAATCTTAGTTCATG
CCAGGGTATTGTTGACACGCTTGAGTCTTTTCAAGATGAAATAGGTGCTCTCAAAAACCATCTTCGTTTCATTGATATCG
GTGGAGGCTACCCTGCATCAACTTGTGGTTCTGATACAGCATCAATCCTTGAACAATATTCGGTCAAGATAGCTTTACAG
CTACGGAGGTTAGGAATTGATTTTCACAAGACCCCCCTTATACTGGAGCCTGGCCGTGCATTAACAGAAGATTTTGGCTA
TCTAGTGACTAGAATCGTTTTTGCAAAATGTCGTTATTCCACTAATGTGATCACCACCGCGGTGCCCGGAACAAACATAA
GGTCTGCTCAGTATCACAACCATCGTAAGGTATTGATTATTCCAGAACGCCCTGTTAATTGTGAACACAGCGTTGCAGAT
GTTTACGGTTCAAACTGCTATGAAAACGATATCATTGCAAAAAATGTACCGGTCCCGTTTGACCTTTCACTCGATGATAA
AATAGCTATTTTTTCCTGTGGTGCTTATGACATCATGAATTCTAGTGACTGGATTCGGAAACGACCGCCAATAATCGTAA
TTTCGAACGGTAAGACTTACTATGAACATTACCGATTTGCCGGGTGA

Upstream 100 bases:

>100_bases
AGCAGCAACTTGCTTTTGACCGTTACTATAATACCCGGCTGTTGTTGAACGAGCATGCAAAATATCAGTCCGTTGCTTTG
TGGGTGATGAGAGTTAAAAA

Downstream 100 bases:

>100_bases
GTATCTTAATGGGAAGAAAATTCACCTCTTGGTTCCTGACCTTAGTAGAAGTCAGGAAATGCATCAATTGATTGTGAATT
TTTCAAACTTACACCGCGAG

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTLSTIDLFNLSENEDYVYILDLDAMTQFVREFRGIWDKQFPHVIFAYSFKSNNIASVTQLMFREGFSAEVVSLHELKLA
INDGFFGTNIFFDGPVKLDNEIEFALSNNVNIQCDNITEIERVLALAANTNAEPHISLRLSSDYRGQGLSRFGMDKDEWN
EAIALLTTHGILCNGIHVHSGSNLSSCQGIVDTLESFQDEIGALKNHLRFIDIGGGYPASTCGSDTASILEQYSVKIALQ
LRRLGIDFHKTPLILEPGRALTEDFGYLVTRIVFAKCRYSTNVITTAVPGTNIRSAQYHNHRKVLIIPERPVNCEHSVAD
VYGSNCYENDIIAKNVPVPFDLSLDDKIAIFSCGAYDIMNSSDWIRKRPPIIVISNGKTYYEHYRFAG

Sequences:

>Translated_388_residues
MTLSTIDLFNLSENEDYVYILDLDAMTQFVREFRGIWDKQFPHVIFAYSFKSNNIASVTQLMFREGFSAEVVSLHELKLA
INDGFFGTNIFFDGPVKLDNEIEFALSNNVNIQCDNITEIERVLALAANTNAEPHISLRLSSDYRGQGLSRFGMDKDEWN
EAIALLTTHGILCNGIHVHSGSNLSSCQGIVDTLESFQDEIGALKNHLRFIDIGGGYPASTCGSDTASILEQYSVKIALQ
LRRLGIDFHKTPLILEPGRALTEDFGYLVTRIVFAKCRYSTNVITTAVPGTNIRSAQYHNHRKVLIIPERPVNCEHSVAD
VYGSNCYENDIIAKNVPVPFDLSLDDKIAIFSCGAYDIMNSSDWIRKRPPIIVISNGKTYYEHYRFAG
>Mature_387_residues
TLSTIDLFNLSENEDYVYILDLDAMTQFVREFRGIWDKQFPHVIFAYSFKSNNIASVTQLMFREGFSAEVVSLHELKLAI
NDGFFGTNIFFDGPVKLDNEIEFALSNNVNIQCDNITEIERVLALAANTNAEPHISLRLSSDYRGQGLSRFGMDKDEWNE
AIALLTTHGILCNGIHVHSGSNLSSCQGIVDTLESFQDEIGALKNHLRFIDIGGGYPASTCGSDTASILEQYSVKIALQL
RRLGIDFHKTPLILEPGRALTEDFGYLVTRIVFAKCRYSTNVITTAVPGTNIRSAQYHNHRKVLIIPERPVNCEHSVADV
YGSNCYENDIIAKNVPVPFDLSLDDKIAIFSCGAYDIMNSSDWIRKRPPIIVISNGKTYYEHYRFAG

Specific function: Unknown

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Drosophila melanogaster, GI24586472, Length=276, Percent_Identity=25.3623188405797, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 43532; Mature: 43401

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSTIDLFNLSENEDYVYILDLDAMTQFVREFRGIWDKQFPHVIFAYSFKSNNIASVTQ
CCEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHH
LMFREGFSAEVVSLHELKLAINDGFFGTNIFFDGPVKLDNEIEFALSNNVNIQCDNITEI
HHHHCCCCCEEEEEEEEEEEEECCEEECEEEECCCEEECCCEEEEECCCCEEEECCHHHH
ERVLALAANTNAEPHISLRLSSDYRGQGLSRFGMDKDEWNEAIALLTTHGILCNGIHVHS
HHHHHHHCCCCCCCEEEEEECCCCCCCCHHHCCCCHHHHHHHEEEEEECCEEECCEEEEC
GSNLSSCQGIVDTLESFQDEIGALKNHLRFIDIGGGYPASTCGSDTASILEQYSVKIALQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEE
LRRLGIDFHKTPLILEPGRALTEDFGYLVTRIVFAKCRYSTNVITTAVPGTNIRSAQYHN
EHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEECC
HRKVLIIPERPVNCEHSVADVYGSNCYENDIIAKNVPVPFDLSLDDKIAIFSCGAYDIMN
CCEEEEECCCCCCCCCHHHHHHCCCCCCCCEEECCCCCCEECCCCCCEEEEECCCHHCCC
SSDWIRKRPPIIVISNGKTYYEHYRFAG
CCCHHHCCCCEEEEECCCEEEHHEEECC
>Mature Secondary Structure 
TLSTIDLFNLSENEDYVYILDLDAMTQFVREFRGIWDKQFPHVIFAYSFKSNNIASVTQ
CEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHH
LMFREGFSAEVVSLHELKLAINDGFFGTNIFFDGPVKLDNEIEFALSNNVNIQCDNITEI
HHHHCCCCCEEEEEEEEEEEEECCEEECEEEECCCEEECCCEEEEECCCCEEEECCHHHH
ERVLALAANTNAEPHISLRLSSDYRGQGLSRFGMDKDEWNEAIALLTTHGILCNGIHVHS
HHHHHHHCCCCCCCEEEEEECCCCCCCCHHHCCCCHHHHHHHEEEEEECCEEECCEEEEC
GSNLSSCQGIVDTLESFQDEIGALKNHLRFIDIGGGYPASTCGSDTASILEQYSVKIALQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEE
LRRLGIDFHKTPLILEPGRALTEDFGYLVTRIVFAKCRYSTNVITTAVPGTNIRSAQYHN
EHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEECC
HRKVLIIPERPVNCEHSVADVYGSNCYENDIIAKNVPVPFDLSLDDKIAIFSCGAYDIMN
CCEEEEECCCCCCCCCHHHHHHCCCCCCCCEEECCCCCCEECCCCCCEEEEECCCHHCCC
SSDWIRKRPPIIVISNGKTYYEHYRFAG
CCCHHHCCCCEEEEECCCEEEHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]