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The map label for this gene is yeeF

Identifier: 51595905

GI number: 51595905

Start: 1889123

End: 1890514

Strand: Direct

Name: yeeF

Synonym: YPTB1568

Alternate gene names: 51595905

Gene position: 1889123-1890514 (Clockwise)

Preceding gene: 51595904

Following gene: 51595907

Centisome position: 39.82

GC content: 51.36

Gene sequence:

>1392_bases
ATGGCGCATGATGCAACTGTTGCCGTCGGCACGAATCAAACGGGTACCAATAACCGCGTCCAACTCAGAAAAACCCTGAC
GTTGGTTCAAGTGGTAATGATGGGTCTGGCTTATCTACAGCCTATGACCATTTTTGATACTTTCGGTATTGTATCCGGCC
TGACCGATGGTCATGTCGCGACCTCTTACGCCATTGCGTTGATTGCGGTGCTGTTCACGGCCGTCAGCTATGGCAAATTG
GTTAAGCGCTTCCCGTCTGCGGGCTCCGCTTATACCTACGCCCAGAAATCCATCAGCCCGAATGTTGGCTTTATGGTGGG
TTGGTCATCATTGCTGGACTACCTGTTCATGCCGATGATCAACATTCTGTTGGCAAAAATTTATCTTGAGGCGATTTTCC
CTGGTGTGCCGTCGTGGATTTTTGTCGGTGCGCTGGTCAGCCTAATGACGCTGTTCAACCTGCGTGGCATCAATATCGTC
GCGAACCTGAACTCGGTCATTGTGGTGGTACAGGTGGCGATCATGGTGGTCTTTATGGGGCTGCTGATCCATGGCGTTTA
TCAAGGCGAAGGGGCTGGTACGTTAGTCAGTGCGCGGCCGTTCTATTCTGAAAATGCGCATTTGGTGCCAATGATAACCG
GGGCCACGATACTCTGCTTCTCGTTCCTTGGTTTCGATGGGATCAGCTCCTTGTCGGAAGAGACCCCGAATGCCGGTAAA
GTGATCCCGAAAGCGATTTTCCTGACAGCGTTGATTGGTGGCATCATCTTTATCGCGGTGTCTTACTGCTTGCAGCTCTA
TTTCCCGAATATTTCGCGCTTCACCGATCCTGAAGCGTCACAGCCGGAAATCATGCTGTTTGTGGCGGGTAAATTCTTCC
AGTCAGTGATCCTGTGTTTCTCCTGTGTCACCGTATTGGCATCAGGTATGGCCGCACACGCAGGGGTTTCACGTCTGCTG
TATGTGATGGGCCGTGATGGTGTATTCCCAGAGAAAGTGTTCGGTTATGTGCACCCTAAATGGCGTACTCCGGCGATTAA
CGTTCTGTTAGTGGGTGGCGTGGCATTGTCCGCTATCTCATTTGATCTGGTAACGGCAACGGCATTGATTAACTTTGGTG
CGCTGGTGGCGTTCACCTTCGTTAACTTGTCTGTGATTGCTCAGTTCTATGTTCGTGAACGCCGCAACAGTACGTTCAAG
GATCACTTCAACTACCTGATTCTGCCAATGATTGGTGCGGGTACGGTGGGGGTACTGTGGGTGAATCTGGAAAGTAGTTC
AATGACGTTGGGCCTGGTCTGGGGCGCAATTGGGTTGAGCTATATGGTCTGGAAAACGCGCGCTTTCCGTCGGGCGCTGC
CGCAGTTTACTGAAGAACCTGCCCAGTTATAA

Upstream 100 bases:

>100_bases
TCCCCACTTACGTATCCCAGGCAGATACGAAGTTTCCCCGTCACTTTTAACCGCTGCGAGACATTTGCGAATCGGGTTGA
AGGTATGGGGAGGCTGAATC

Downstream 100 bases:

>100_bases
GGCAAGCTCACGCTCATCATTAAGTTTATCAATCCGGCACAGTCTCTGTTGCCGGATTTTTTGTATTCAGAAAACCAGGT
CAGAGCGTATTGCCGTGCGG

Product: APC family amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MAHDATVAVGTNQTGTNNRVQLRKTLTLVQVVMMGLAYLQPMTIFDTFGIVSGLTDGHVATSYAIALIAVLFTAVSYGKL
VKRFPSAGSAYTYAQKSISPNVGFMVGWSSLLDYLFMPMINILLAKIYLEAIFPGVPSWIFVGALVSLMTLFNLRGINIV
ANLNSVIVVVQVAIMVVFMGLLIHGVYQGEGAGTLVSARPFYSENAHLVPMITGATILCFSFLGFDGISSLSEETPNAGK
VIPKAIFLTALIGGIIFIAVSYCLQLYFPNISRFTDPEASQPEIMLFVAGKFFQSVILCFSCVTVLASGMAAHAGVSRLL
YVMGRDGVFPEKVFGYVHPKWRTPAINVLLVGGVALSAISFDLVTATALINFGALVAFTFVNLSVIAQFYVRERRNSTFK
DHFNYLILPMIGAGTVGVLWVNLESSSMTLGLVWGAIGLSYMVWKTRAFRRALPQFTEEPAQL

Sequences:

>Translated_463_residues
MAHDATVAVGTNQTGTNNRVQLRKTLTLVQVVMMGLAYLQPMTIFDTFGIVSGLTDGHVATSYAIALIAVLFTAVSYGKL
VKRFPSAGSAYTYAQKSISPNVGFMVGWSSLLDYLFMPMINILLAKIYLEAIFPGVPSWIFVGALVSLMTLFNLRGINIV
ANLNSVIVVVQVAIMVVFMGLLIHGVYQGEGAGTLVSARPFYSENAHLVPMITGATILCFSFLGFDGISSLSEETPNAGK
VIPKAIFLTALIGGIIFIAVSYCLQLYFPNISRFTDPEASQPEIMLFVAGKFFQSVILCFSCVTVLASGMAAHAGVSRLL
YVMGRDGVFPEKVFGYVHPKWRTPAINVLLVGGVALSAISFDLVTATALINFGALVAFTFVNLSVIAQFYVRERRNSTFK
DHFNYLILPMIGAGTVGVLWVNLESSSMTLGLVWGAIGLSYMVWKTRAFRRALPQFTEEPAQL
>Mature_462_residues
AHDATVAVGTNQTGTNNRVQLRKTLTLVQVVMMGLAYLQPMTIFDTFGIVSGLTDGHVATSYAIALIAVLFTAVSYGKLV
KRFPSAGSAYTYAQKSISPNVGFMVGWSSLLDYLFMPMINILLAKIYLEAIFPGVPSWIFVGALVSLMTLFNLRGINIVA
NLNSVIVVVQVAIMVVFMGLLIHGVYQGEGAGTLVSARPFYSENAHLVPMITGATILCFSFLGFDGISSLSEETPNAGKV
IPKAIFLTALIGGIIFIAVSYCLQLYFPNISRFTDPEASQPEIMLFVAGKFFQSVILCFSCVTVLASGMAAHAGVSRLLY
VMGRDGVFPEKVFGYVHPKWRTPAINVLLVGGVALSAISFDLVTATALINFGALVAFTFVNLSVIAQFYVRERRNSTFKD
HFNYLILPMIGAGTVGVLWVNLESSSMTLGLVWGAIGLSYMVWKTRAFRRALPQFTEEPAQL

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=428, Percent_Identity=22.8971962616822, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI181337167, Length=413, Percent_Identity=24.9394673123487, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI258614005, Length=411, Percent_Identity=23.6009732360097, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI258614003, Length=411, Percent_Identity=23.6009732360097, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI114326544, Length=192, Percent_Identity=26.5625, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI114326550, Length=192, Percent_Identity=26.5625, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI110347453, Length=428, Percent_Identity=23.8317757009346, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI258645169, Length=413, Percent_Identity=23.0024213075061, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082023, Length=447, Percent_Identity=73.6017897091723, Blast_Score=673, Evalue=0.0,
Organism=Escherichia coli, GI87081869, Length=440, Percent_Identity=66.8181818181818, Blast_Score=625, Evalue=1e-180,
Organism=Escherichia coli, GI1788480, Length=343, Percent_Identity=23.9067055393586, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786789, Length=440, Percent_Identity=22.2727272727273, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082250, Length=328, Percent_Identity=21.6463414634146, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786602, Length=296, Percent_Identity=24.6621621621622, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=398, Percent_Identity=25.8793969849246, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17533459, Length=429, Percent_Identity=25.4079254079254, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17531343, Length=399, Percent_Identity=25.062656641604, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24667468, Length=411, Percent_Identity=27.007299270073, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI221512776, Length=411, Percent_Identity=24.0875912408759, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24666159, Length=411, Percent_Identity=24.0875912408759, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24668806, Length=424, Percent_Identity=23.8207547169811, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356285, Length=424, Percent_Identity=23.8207547169811, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24668802, Length=424, Percent_Identity=23.8207547169811, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281366235, Length=415, Percent_Identity=25.7831325301205, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007820, Length=415, Percent_Identity=25.7831325301205, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007818, Length=404, Percent_Identity=25.4950495049505, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI85725152, Length=404, Percent_Identity=25.4950495049505, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50183; Mature: 50052

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHDATVAVGTNQTGTNNRVQLRKTLTLVQVVMMGLAYLQPMTIFDTFGIVSGLTDGHVA
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHH
TSYAIALIAVLFTAVSYGKLVKRFPSAGSAYTYAQKSISPNVGFMVGWSSLLDYLFMPMI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEECHHHHHHHHHHHHH
NILLAKIYLEAIFPGVPSWIFVGALVSLMTLFNLRGINIVANLNSVIVVVQVAIMVVFMG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHH
LLIHGVYQGEGAGTLVSARPFYSENAHLVPMITGATILCFSFLGFDGISSLSEETPNAGK
HHHHHHHCCCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
VIPKAIFLTALIGGIIFIAVSYCLQLYFPNISRFTDPEASQPEIMLFVAGKFFQSVILCF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHH
SCVTVLASGMAAHAGVSRLLYVMGRDGVFPEKVFGYVHPKWRTPAINVLLVGGVALSAIS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEEEECHHHHHHHH
FDLVTATALINFGALVAFTFVNLSVIAQFYVRERRNSTFKDHFNYLILPMIGAGTVGVLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEEEEECCCCEEEEE
VNLESSSMTLGLVWGAIGLSYMVWKTRAFRRALPQFTEEPAQL
EEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AHDATVAVGTNQTGTNNRVQLRKTLTLVQVVMMGLAYLQPMTIFDTFGIVSGLTDGHVA
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHH
TSYAIALIAVLFTAVSYGKLVKRFPSAGSAYTYAQKSISPNVGFMVGWSSLLDYLFMPMI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEECHHHHHHHHHHHHH
NILLAKIYLEAIFPGVPSWIFVGALVSLMTLFNLRGINIVANLNSVIVVVQVAIMVVFMG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHH
LLIHGVYQGEGAGTLVSARPFYSENAHLVPMITGATILCFSFLGFDGISSLSEETPNAGK
HHHHHHHCCCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
VIPKAIFLTALIGGIIFIAVSYCLQLYFPNISRFTDPEASQPEIMLFVAGKFFQSVILCF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHH
SCVTVLASGMAAHAGVSRLLYVMGRDGVFPEKVFGYVHPKWRTPAINVLLVGGVALSAIS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEEEECHHHHHHHH
FDLVTATALINFGALVAFTFVNLSVIAQFYVRERRNSTFKDHFNYLILPMIGAGTVGVLW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCEEEEEEECCCCEEEEE
VNLESSSMTLGLVWGAIGLSYMVWKTRAFRRALPQFTEEPAQL
EEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]