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The map label for this gene is fabZ [H]

Identifier: 51595809

GI number: 51595809

Start: 1767062

End: 1767520

Strand: Direct

Name: fabZ [H]

Synonym: YPTB1472

Alternate gene names: 51595809

Gene position: 1767062-1767520 (Clockwise)

Preceding gene: 51595808

Following gene: 51595810

Centisome position: 37.24

GC content: 39.87

Gene sequence:

>459_bases
TTGAATACATCATTTGGACAAGATATCATTAAAAAAATGATACCGCATCGTGAACCATTTTTAATGGTCGACAACGTAGA
GCTGATCAATATTGAATGCAGGTTAATAAAAGCAATAAGAAGAGTTGACGAAAAAGACCCGGTATTTGGTGGTCATTTCC
CCAATGACCCTATATATCCAGGTGTATTGCAACAAGAAAGTATGTTTCAAACCGCGCTTATTTTAATGTATTTTCTGCTA
AATGAAACGGCTATTCCGCCAGCAGAGGAGAATATCATCCACGCAGTGGGAACACGAGTATACGATGTCTTTCACTTGTC
CGCAGTACGCCCAGGAGAATTAATGACAATCCGTTGTTGTATTACAGAATACGACACATTTCTTGCCACCGCCATTGTTC
AAATCACGGTTAACGATCAGATCGTAACCGTCGGAAAAGGAGAGTTTCATGTCTTCTGA

Upstream 100 bases:

>100_bases
GATACCAAACGATTTTTATGGGCTATATTTAAATATGAAAAATACTGAATTAAATTTTTTAAAAACGAATTTTTTATTTA
ACCAAGATATTACTAATGAA

Downstream 100 bases:

>100_bases
TCGTATCGTTATCACTGGCGTTGCCATTAATACTCCCATTGGTGACACATTAGATCTAGTGGGTAATAATTTATTATCTG
GAAAATCAGCCATCGGCTAC

Product: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydrase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPIYPGVLQQESMFQTALILMYFLL
NETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVNDQIVTVGKGEFHVF

Sequences:

>Translated_152_residues
MNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPIYPGVLQQESMFQTALILMYFLL
NETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVNDQIVTVGKGEFHVF
>Mature_152_residues
MNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPIYPGVLQQESMFQTALILMYFLL
NETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVNDQIVTVGKGEFHVF

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=68, Percent_Identity=47.0588235294118, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17295; Mature: 17295

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPIYP
CCCCHHHHHHHHHCCCCCCEEEECCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCC
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
ITEYDTFLATAIVQITVNDQIVTVGKGEFHVF
HHHHHHHHEEEEEEEEECCEEEEECCCEEEEC
>Mature Secondary Structure
MNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPIYP
CCCCHHHHHHHHHCCCCCCEEEECCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCC
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
ITEYDTFLATAIVQITVNDQIVTVGKGEFHVF
HHHHHHHHEEEEEEEEECCEEEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]