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The map label for this gene is ycaD [C]

Identifier: 51595745

GI number: 51595745

Start: 1677806

End: 1678954

Strand: Direct

Name: ycaD [C]

Synonym: YPTB1405

Alternate gene names: 51595745

Gene position: 1677806-1678954 (Clockwise)

Preceding gene: 51595744

Following gene: 51595747

Centisome position: 35.36

GC content: 49.61

Gene sequence:

>1149_bases
ATGTCCGCATATTCTCGCCCCGTGCTACTCCTGCTTTGTGGGCTTTTGCTGTTCACGATCTCTATCGCGGTTTTAAATAC
ACTGGTTCCCTTATGGTTATCACATCAACAGTTGCCGACTTGGCAAGTGGGGATGGTGAGCTCATCTTATTTCACCGGTA
ATCTGGTAGGAACGTTGATTGCAGGCCGCTTTATTCAGCAACTCGGTTTTAATCGCAGTTATCATTGCTCCTGTATATTG
TTTGCACTGGCAACTTGTGGGCTGATGCTAACGGTTGATTTTTGGAGCTGGTTGGGTTGGCGCTTTTTGGCGGGCATTGC
CTGCGCGCTGATTTGGGTCATTGTCGAAAGTGCTTTATTACGCAGTGGTACCTTAACCAACCGCGGACAACTACTGGCGG
CCTACATGATGGTTTACTATTTAGGGACCGTCATCGGGCAATTATTATTGGGTATAGTCTCCACACAACTGCTCAGTGTT
ATTCCTTGGGTGGGGGCGCTGGTGATTACGGCAATGCTGCCGCTACTATTTGCCCAGTTCTCACATCAAAGTCGTCACGA
GTCACCGCCTATTGCGGTTTGGCCTATGTTAAAACGCCGCAGCGCCCGTTTAGGTATTAATGGATGTATTATCTCTGGTG
TACTCTTGGGGTCACTCTATGGGTTACTGCCACTGTATTTATCCCATAAGGGGATGAGTGACGCCAGCGTGGGGGGGTGG
ATGGCGTTGCTGGTCAGTTCAGGGATTATTGGGCAATGGCCTATGGGAAGAATGGCTGACCGCTATGGCCGCTTACTGGT
ACTGCGGATCCAAGTGTTTGTCGTCATCCTCGGTAGTGTGGCGATCTTGGGTAATTACGCAATGGCGCCGGCGTTATTCA
TTTTAGGCTGCGCGGGTTTCACTTTGTATCCGGTTGCTATGGCCTGGGCGTGTGAAAAAGCCAGCGCTGATGAATTGGTC
GCGATGAATCAGGCGTTACTGATGAGTTATACCCTTGGGAGCCTGGCCGGGCCGACGATGACGTCACTGCTGATGCAGCG
CTATTCAGATAATTTATTATTTATCATGATAGCAGGTGTCGCATTCGTGTATTTGATGATGCTGTTGAGAAAGCCAGATC
ACCAACAAACGCCTTATGCTGCGGTATAA

Upstream 100 bases:

>100_bases
ATGACATATTGTGCTATCCCTCCCCACTGGGTAATTGACTTTTTTATCGCCAGTGGCATGATGCGCTCACTTTTATTGTC
CCGACGGTTTCTGTCTTACT

Downstream 100 bases:

>100_bases
AAGTAAGCCGTATCAATATAAAACGGTATCAATATATAAGACAACGCCGCCAGCGGATTCATCCAGCATGGCGGCAGTTG
TTAGGCCAAACCTAATACAC

Product: MFS family transporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSAYSRPVLLLLCGLLLFTISIAVLNTLVPLWLSHQQLPTWQVGMVSSSYFTGNLVGTLIAGRFIQQLGFNRSYHCSCIL
FALATCGLMLTVDFWSWLGWRFLAGIACALIWVIVESALLRSGTLTNRGQLLAAYMMVYYLGTVIGQLLLGIVSTQLLSV
IPWVGALVITAMLPLLFAQFSHQSRHESPPIAVWPMLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHKGMSDASVGGW
MALLVSSGIIGQWPMGRMADRYGRLLVLRIQVFVVILGSVAILGNYAMAPALFILGCAGFTLYPVAMAWACEKASADELV
AMNQALLMSYTLGSLAGPTMTSLLMQRYSDNLLFIMIAGVAFVYLMMLLRKPDHQQTPYAAV

Sequences:

>Translated_382_residues
MSAYSRPVLLLLCGLLLFTISIAVLNTLVPLWLSHQQLPTWQVGMVSSSYFTGNLVGTLIAGRFIQQLGFNRSYHCSCIL
FALATCGLMLTVDFWSWLGWRFLAGIACALIWVIVESALLRSGTLTNRGQLLAAYMMVYYLGTVIGQLLLGIVSTQLLSV
IPWVGALVITAMLPLLFAQFSHQSRHESPPIAVWPMLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHKGMSDASVGGW
MALLVSSGIIGQWPMGRMADRYGRLLVLRIQVFVVILGSVAILGNYAMAPALFILGCAGFTLYPVAMAWACEKASADELV
AMNQALLMSYTLGSLAGPTMTSLLMQRYSDNLLFIMIAGVAFVYLMMLLRKPDHQQTPYAAV
>Mature_381_residues
SAYSRPVLLLLCGLLLFTISIAVLNTLVPLWLSHQQLPTWQVGMVSSSYFTGNLVGTLIAGRFIQQLGFNRSYHCSCILF
ALATCGLMLTVDFWSWLGWRFLAGIACALIWVIVESALLRSGTLTNRGQLLAAYMMVYYLGTVIGQLLLGIVSTQLLSVI
PWVGALVITAMLPLLFAQFSHQSRHESPPIAVWPMLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHKGMSDASVGGWM
ALLVSSGIIGQWPMGRMADRYGRLLVLRIQVFVVILGSVAILGNYAMAPALFILGCAGFTLYPVAMAWACEKASADELVA
MNQALLMSYTLGSLAGPTMTSLLMQRYSDNLLFIMIAGVAFVYLMMLLRKPDHQQTPYAAV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family

Homologues:

Organism=Escherichia coli, GI1787126, Length=382, Percent_Identity=65.7068062827225, Blast_Score=501, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1380_YERPE (Q8ZGC3)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AF0168
- RefSeq:   NP_992579.1
- RefSeq:   YP_002346403.1
- ProteinModelPortal:   Q8ZGC3
- GeneID:   1174221
- GeneID:   2764830
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO1380
- KEGG:   ypm:YP_1213
- HOGENOM:   HBG302458
- OMA:   TISIFAT
- ProtClustDB:   PRK03633
- BioCyc:   YPES214092:YPO1380-MONOMER
- HAMAP:   MF_01149
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 41688; Mature: 41556

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1a1a0e28)-; HASH(0x19fd0744)-; HASH(0x1a30bf8c)-; HASH(0x41023b20)-; HASH(0x1a36c1ac)-; HASH(0x1a2db848)-; HASH(0x1a2bec9c)-; HASH(0x19fd0890)-; HASH(0x1a25944c)-; HASH(0x1a76bba4)-; HASH(0x1a511664)-; HASH(0x1a821f48)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAYSRPVLLLLCGLLLFTISIAVLNTLVPLWLSHQQLPTWQVGMVSSSYFTGNLVGTLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHH
AGRFIQQLGFNRSYHCSCILFALATCGLMLTVDFWSWLGWRFLAGIACALIWVIVESALL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGTLTNRGQLLAAYMMVYYLGTVIGQLLLGIVSTQLLSVIPWVGALVITAMLPLLFAQF
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHQSRHESPPIAVWPMLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHKGMSDASVGGW
HHHCCCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
MALLVSSGIIGQWPMGRMADRYGRLLVLRIQVFVVILGSVAILGNYAMAPALFILGCAGF
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TLYPVAMAWACEKASADELVAMNQALLMSYTLGSLAGPTMTSLLMQRYSDNLLFIMIAGV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
AFVYLMMLLRKPDHQQTPYAAV
HHHHHHHHHCCCCCCCCCCCCH
>Mature Secondary Structure 
SAYSRPVLLLLCGLLLFTISIAVLNTLVPLWLSHQQLPTWQVGMVSSSYFTGNLVGTLI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHH
AGRFIQQLGFNRSYHCSCILFALATCGLMLTVDFWSWLGWRFLAGIACALIWVIVESALL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGTLTNRGQLLAAYMMVYYLGTVIGQLLLGIVSTQLLSVIPWVGALVITAMLPLLFAQF
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHQSRHESPPIAVWPMLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHKGMSDASVGGW
HHHCCCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
MALLVSSGIIGQWPMGRMADRYGRLLVLRIQVFVVILGSVAILGNYAMAPALFILGCAGF
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TLYPVAMAWACEKASADELVAMNQALLMSYTLGSLAGPTMTSLLMQRYSDNLLFIMIAGV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
AFVYLMMLLRKPDHQQTPYAAV
HHHHHHHHHCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430