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The map label for this gene is uxuA

Identifier: 51595656

GI number: 51595656

Start: 1567306

End: 1568499

Strand: Direct

Name: uxuA

Synonym: YPTB1315

Alternate gene names: 51595656

Gene position: 1567306-1568499 (Clockwise)

Preceding gene: 51595654

Following gene: 51595659

Centisome position: 33.03

GC content: 49.83

Gene sequence:

>1194_bases
ATGGAACAAACATGGCGTTGGTATGGCCCGAATGATCCGGTGTCGTTAGATGATATCCGTCAAGCGGGTGCTACCGGAGT
AGTCACGGCGTTACACCATATCCCGAATGGTGTTGTGTGGCCAGTCAGTGAGATCAAGCAGCGTCAGGCCGAATTAGCAG
CTAAAAACCTGGTATGGTCTGTTGTGGAAAGTGTGCCTATTCATGAGGACATCAAAACTCATAGCGGTAACTATCAGCAA
TACATTGAAAATTACCAACAAACACTGCGTAACATTGCAGAATGCGGTATTGACACCGTGTGCTACAACTTCATGCCGAT
ACTGGACTGGACGCGTACTGATCTGGAATATGAATTACCAGACGGTTCTAAAGCGTTGCGTTTTGACCAGATAGCTTTTG
CCGCTTTTGAGCTGCATATTCTAAAACGCCCTGGTGCCAGCAATGACTATACGGCGGAAGAACAAGTACAGGCAGAAGCG
TATTTCAACGCGATGACTGAAGCTGATATTGCCAAGCTGACGGGCAATATTATTGCAGGTCTGCCAGGGGCTGAAGAGGG
CTATACGCTGGATCAGTTCCGTGCTCGGTTGGCTGAGTACGATGGGATTGATAAAGCGCAACTGCGTGAGAACATGGCTT
ACTTCCTGCGCGCTATCATTCCGGTGGCGGAACAAGTGGGCTTGCGTATGGCGGTGCACCCAGATGATCCACCGCGCCCA
ATCCTTGGCCTGCCGCGTATCGTTTCAACCATTGAAGATATGCAGTGGCTGAAAGAGACGGTGGATAGCATCCACAACGG
TTTCACCATGTGTACCGGTTCGTATGGTGTGCGTGCTGATAACGATTTGGTGAAGATGATCGAAACCTTTGGTGATCGTA
TTCACTTCACGCATTTGCGTTCCACCTGTCGTGAAGGAAACCCAAAAACCTTCCATGAAGGGGGTCATTTGCAAGGCGAT
GTGGATATGTACTCGGTGGTAAAAGCCATTTTAACCGAAGAACAGCGCCGCCAGTCACTGGGGGATATGCGTCCAATACC
TATGCGTCCGGACCATGGTCATCAGATGCTGGACGATTTGCACAAGAAAACCAATCCGGGCTATTCGGCAATTGGGCGTC
TGAAAGGGCTGGCAGAAGTTCGTGGTGTGGAATTGGCACTGAAACGGACATTTTTCCCCGATCTGAAGCAGTAG

Upstream 100 bases:

>100_bases
CCGTTATCGGCAGAAAAGTCCGTTATCGGCAGAAAAAGGCGGCTTTAACCGTTAGCGGGTTAATTTTATTATTGTTGCGT
ATGCAGAAGGTAAAAATAAA

Downstream 100 bases:

>100_bases
TTTTGCACGATCAGTGAAGAGATAACCGTTAAGGGCCGGTTTCCGGCTCTTAACGTAGAGAGACCCAATAGATTCAAGTT
GCAGAAGGGCGGCCAGCAAG

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWSVVESVPIHEDIKTHSGNYQQ
YIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELPDGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEA
YFNAMTEADIAKLTGNIIAGLPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRP
ILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLRSTCREGNPKTFHEGGHLQGD
VDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDLHKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPDLKQ

Sequences:

>Translated_397_residues
MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWSVVESVPIHEDIKTHSGNYQQ
YIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELPDGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEA
YFNAMTEADIAKLTGNIIAGLPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRP
ILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLRSTCREGNPKTFHEGGHLQGD
VDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDLHKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPDLKQ
>Mature_397_residues
MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWSVVESVPIHEDIKTHSGNYQQ
YIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELPDGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEA
YFNAMTEADIAKLTGNIIAGLPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRP
ILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLRSTCREGNPKTFHEGGHLQGD
VDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDLHKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPDLKQ

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family

Homologues:

Organism=Escherichia coli, GI1790778, Length=392, Percent_Identity=78.5714285714286, Blast_Score=648, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXUA_YERP3 (A7FK86)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001401664.1
- ProteinModelPortal:   A7FK86
- SMR:   A7FK86
- STRING:   A7FK86
- GeneID:   5386374
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_2699
- eggNOG:   COG1312
- HOGENOM:   HBG585927
- OMA:   VHEEIKT
- ProtClustDB:   PRK03906
- BioCyc:   YPSE349747:YPSIP31758_2699-MONOMER
- HAMAP:   MF_00106
- InterPro:   IPR004628
- InterPro:   IPR013022
- Gene3D:   G3DSA:3.20.20.150
- PIRSF:   PIRSF016049
- TIGRFAMs:   TIGR00695

Pfam domain/function: PF03786 UxuA; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =4.2.1.8

Molecular weight: Translated: 44876; Mature: 44876

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHH
VVESVPIHEDIKTHSGNYQQYIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELP
HHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEECC
DGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEAYFNAMTEADIAKLTGNIIAG
CCCCHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCC
LPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRP
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
ILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLR
CCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCEEHHHHH
STCREGNPKTFHEGGHLQGDVDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
HKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPDLKQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEQTWRWYGPNDPVSLDDIRQAGATGVVTALHHIPNGVVWPVSEIKQRQAELAAKNLVWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHH
VVESVPIHEDIKTHSGNYQQYIENYQQTLRNIAECGIDTVCYNFMPILDWTRTDLEYELP
HHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEECC
DGSKALRFDQIAFAAFELHILKRPGASNDYTAEEQVQAEAYFNAMTEADIAKLTGNIIAG
CCCCHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCC
LPGAEEGYTLDQFRARLAEYDGIDKAQLRENMAYFLRAIIPVAEQVGLRMAVHPDDPPRP
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
ILGLPRIVSTIEDMQWLKETVDSIHNGFTMCTGSYGVRADNDLVKMIETFGDRIHFTHLR
CCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCEEHHHHH
STCREGNPKTFHEGGHLQGDVDMYSVVKAILTEEQRRQSLGDMRPIPMRPDHGHQMLDDL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
HKKTNPGYSAIGRLKGLAEVRGVELALKRTFFPDLKQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA