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The map label for this gene is cysS

Identifier: 51595384

GI number: 51595384

Start: 1242263

End: 1243648

Strand: Direct

Name: cysS

Synonym: YPTB1035

Alternate gene names: 51595384

Gene position: 1242263-1243648 (Clockwise)

Preceding gene: 51595379

Following gene: 51595391

Centisome position: 26.18

GC content: 49.71

Gene sequence:

>1386_bases
ATGCTAAAGATTTTTAATACACTGAGTCGCCAAAAAGAGGAATTCAAGCCTATCCATGCCGGTAAAGTGGGTATGTATGT
ATGCGGGATCACTATTTATGACCTGTGTCACATTGGGCATGGGCGCACTTTTGTCGCTTTCGATGTTGTGGCGCGTTATT
TGCGTTATTTAGGCTACTCTCTGACGTATGTCCGCAATGTCACTGACGTTGACGATAAGATCATTAAACGTGCGATTGAG
AATAATGAGACTTGTGAGCAACTGACAACGCGGATGCTGGCAGAGATGCACAAAGATTTTGACGCATTAAATCTTGAGCG
CCCTGATTTGGAGCCGCGTGCGACTCACCATATCGCTGAAATAATTGAGATGACCGAGCGCTTAATTGCTCGGGGCCATG
CTTATGTTGCCTCTAACGGCGATGTGATGTTTGCGGTCGATAGCGATCCTGATTACGGTGTGTTATCCCGACAGGATCTG
GATCAACTACAGGCCGGTGCACGGGTTGAAGTGGCTGATGTTAAACGTAATCCGATGGATTTCGTGCTGTGGAAAATGTC
CAAACCGGGTGAGCCACGCTGGGAATCACCTTGGGGGCCGGGCCGCCCTGGTTGGCATATTGAATGTTCAGCAATGAACG
GCAAACAGTTAGGCGCGCATTTTGATATTCACGGCGGCGGCTCTGATTTGATGTTTCCGCACCACGAGAACGAGATCGCT
CAATCTACCTGCGCACACGATGGCCCGTATGTAAATTACTGGATGCACTCTGGTATGGTGATGATCGACAAAGAGAAAAT
GTCGAAGTCCCTGAATAACTTCTTCACTATTCGCGATGTGCTGGCGTATTACGATGCCGAAACCGTGCGTTATTTCTTGA
TGTCCGGTCATTATCGTAGCCAGCTTAACTACAGCGAAGAGAATCTGAAGCAGGCACGCGCTTCACTGGAGCGTTTATAT
ACCGCGCTGCGCGGTACTGATGCTAACGCTACGCCAGCAGGGGGCGCTGAATTTGAAGCCCGTTTCCGCACGGCAATGGA
TGATGATTTCAATACACCAGAAGCTTATTCGGTGTTGTTTGACATTGCCCGCGAAGTCAACCGCCTGAAAAACGAAGATA
TGGCCGCTGCCAATGGTCTGGCCGCTGAGTTACGTAAATTGGCTCAGGTGCTGGGCTTATTAGAACAGGACCCAGAGCTG
TTTTTACAAGGCGGTGCGCAGGCTGATGACGACGAAGTAGCAAAAATCGAAGCCCTGATTAAGCAACGTAATGATGCCCG
CAGCAGCAAAAATTGGGCGTTGGCAGATGCCGCACGTGATCAATTGAATGATCTGGGTATTGTGCTGGAAGATGGCCCGC
AAGGCACGACATGGCGCCGCAAGTAA

Upstream 100 bases:

>100_bases
ATGGGCGAAAAAGTGCTGTATCAGAGACTGATTTACCGCATAATCTGATGATATCTTGTTTATCTATGCGTACCGCAAAA
TAAAACCACGGAATGTCCCA

Downstream 100 bases:

>100_bases
CGTTGTTTGATACGCTTTTAAGGTTATGGAATAAGGCGGGATAGGGAACTGTTTAGCGAGCTATATTTGTTAGCTGACAC
TATTTATTAGTGGGTACTAT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MLKIFNTLSRQKEEFKPIHAGKVGMYVCGITIYDLCHIGHGRTFVAFDVVARYLRYLGYSLTYVRNVTDVDDKIIKRAIE
NNETCEQLTTRMLAEMHKDFDALNLERPDLEPRATHHIAEIIEMTERLIARGHAYVASNGDVMFAVDSDPDYGVLSRQDL
DQLQAGARVEVADVKRNPMDFVLWKMSKPGEPRWESPWGPGRPGWHIECSAMNGKQLGAHFDIHGGGSDLMFPHHENEIA
QSTCAHDGPYVNYWMHSGMVMIDKEKMSKSLNNFFTIRDVLAYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLY
TALRGTDANATPAGGAEFEARFRTAMDDDFNTPEAYSVLFDIAREVNRLKNEDMAAANGLAAELRKLAQVLGLLEQDPEL
FLQGGAQADDDEVAKIEALIKQRNDARSSKNWALADAARDQLNDLGIVLEDGPQGTTWRRK

Sequences:

>Translated_461_residues
MLKIFNTLSRQKEEFKPIHAGKVGMYVCGITIYDLCHIGHGRTFVAFDVVARYLRYLGYSLTYVRNVTDVDDKIIKRAIE
NNETCEQLTTRMLAEMHKDFDALNLERPDLEPRATHHIAEIIEMTERLIARGHAYVASNGDVMFAVDSDPDYGVLSRQDL
DQLQAGARVEVADVKRNPMDFVLWKMSKPGEPRWESPWGPGRPGWHIECSAMNGKQLGAHFDIHGGGSDLMFPHHENEIA
QSTCAHDGPYVNYWMHSGMVMIDKEKMSKSLNNFFTIRDVLAYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLY
TALRGTDANATPAGGAEFEARFRTAMDDDFNTPEAYSVLFDIAREVNRLKNEDMAAANGLAAELRKLAQVLGLLEQDPEL
FLQGGAQADDDEVAKIEALIKQRNDARSSKNWALADAARDQLNDLGIVLEDGPQGTTWRRK
>Mature_461_residues
MLKIFNTLSRQKEEFKPIHAGKVGMYVCGITIYDLCHIGHGRTFVAFDVVARYLRYLGYSLTYVRNVTDVDDKIIKRAIE
NNETCEQLTTRMLAEMHKDFDALNLERPDLEPRATHHIAEIIEMTERLIARGHAYVASNGDVMFAVDSDPDYGVLSRQDL
DQLQAGARVEVADVKRNPMDFVLWKMSKPGEPRWESPWGPGRPGWHIECSAMNGKQLGAHFDIHGGGSDLMFPHHENEIA
QSTCAHDGPYVNYWMHSGMVMIDKEKMSKSLNNFFTIRDVLAYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLY
TALRGTDANATPAGGAEFEARFRTAMDDDFNTPEAYSVLFDIAREVNRLKNEDMAAANGLAAELRKLAQVLGLLEQDPEL
FLQGGAQADDDEVAKIEALIKQRNDARSSKNWALADAARDQLNDLGIVLEDGPQGTTWRRK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=387, Percent_Identity=40.0516795865633, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI62240992, Length=260, Percent_Identity=40, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI10835051, Length=260, Percent_Identity=40, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI303304987, Length=260, Percent_Identity=40, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI21269877, Length=260, Percent_Identity=40, Blast_Score=192, Evalue=6e-49,
Organism=Escherichia coli, GI1786737, Length=461, Percent_Identity=83.7310195227766, Blast_Score=799, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17509795, Length=237, Percent_Identity=40.084388185654, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17509797, Length=237, Percent_Identity=40.084388185654, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6324082, Length=413, Percent_Identity=31.4769975786925, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI19922218, Length=500, Percent_Identity=34.8, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI19922364, Length=260, Percent_Identity=38.8461538461538, Blast_Score=178, Evalue=9e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 52148; Mature: 52148

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIFNTLSRQKEEFKPIHAGKVGMYVCGITIYDLCHIGHGRTFVAFDVVARYLRYLGYS
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCH
LTYVRNVTDVDDKIIKRAIENNETCEQLTTRMLAEMHKDFDALNLERPDLEPRATHHIAE
HHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
IIEMTERLIARGHAYVASNGDVMFAVDSDPDYGVLSRQDLDQLQAGARVEVADVKRNPMD
HHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCE
FVLWKMSKPGEPRWESPWGPGRPGWHIECSAMNGKQLGAHFDIHGGGSDLMFPHHENEIA
EEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCHHHH
QSTCAHDGPYVNYWMHSGMVMIDKEKMSKSLNNFFTIRDVLAYYDAETVRYFLMSGHYRS
HHHHCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
QLNYSEENLKQARASLERLYTALRGTDANATPAGGAEFEARFRTAMDDDFNTPEAYSVLF
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
DIAREVNRLKNEDMAAANGLAAELRKLAQVLGLLEQDPELFLQGGAQADDDEVAKIEALI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHH
KQRNDARSSKNWALADAARDQLNDLGIVLEDGPQGTTWRRK
HHHHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MLKIFNTLSRQKEEFKPIHAGKVGMYVCGITIYDLCHIGHGRTFVAFDVVARYLRYLGYS
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCH
LTYVRNVTDVDDKIIKRAIENNETCEQLTTRMLAEMHKDFDALNLERPDLEPRATHHIAE
HHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
IIEMTERLIARGHAYVASNGDVMFAVDSDPDYGVLSRQDLDQLQAGARVEVADVKRNPMD
HHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCE
FVLWKMSKPGEPRWESPWGPGRPGWHIECSAMNGKQLGAHFDIHGGGSDLMFPHHENEIA
EEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCHHHH
QSTCAHDGPYVNYWMHSGMVMIDKEKMSKSLNNFFTIRDVLAYYDAETVRYFLMSGHYRS
HHHHCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
QLNYSEENLKQARASLERLYTALRGTDANATPAGGAEFEARFRTAMDDDFNTPEAYSVLF
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
DIAREVNRLKNEDMAAANGLAAELRKLAQVLGLLEQDPELFLQGGAQADDDEVAKIEALI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHH
KQRNDARSSKNWALADAARDQLNDLGIVLEDGPQGTTWRRK
HHHHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA