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The map label for this gene is crl

Identifier: 51595253

GI number: 51595253

Start: 1090716

End: 1091117

Strand: Direct

Name: crl

Synonym: YPTB0903

Alternate gene names: 51595253

Gene position: 1090716-1091117 (Clockwise)

Preceding gene: 51595252

Following gene: 51595254

Centisome position: 22.99

GC content: 44.03

Gene sequence:

>402_bases
ATGACGTTAACCAGTGCTCATCCTAAAAGTAAGCTTATGAAACGTTTTGCAGCTTTGGGGCCATACCTGCGAGAAGGGCA
GTGCCAGAACGACCATTTTTTCTTTGATTGTTTAGCTGTATGCATCAATGTGAAGCTTGCCCCAGAGAAACGTGAGTTCT
GGGGGTGGTGGATAGAACTGGAGCCATCGGCTGGTCGCTTTACTTATGTTTATCAACTCGGACTCTTTAATAAAGAAGGC
AACTGGAACGCGGAAAAAATTAGCGATCCTGAAGTTCAGGATAAACTTGAAAGTACACTGCGTAGTTTTCATCTGCGGCT
CGAAGAGATGCTAGCTTCCATTGACATGAAATTAGAACCTGCTGCGGATTTTAACGATCAGCCTGTTAAGTTATCTGCTT
GA

Upstream 100 bases:

>100_bases
TATTGCAAACCAGCGAATGGTTAGAAGATAAAATGCGTTAATGAGTTGCTAAATTTTAATAGTTTGCTAAAAAGGTTCGT
CTACATAAGGAGATTTAAGT

Downstream 100 bases:

>100_bases
TAATACGCTTACCTAGGTTTGATTAGGCCAATTCCGTGGTCATAAACTGTCCCCATTACCCCCTTTCTGCACAATAAAGG
GGGTGATTTCGTATCAAGCC

Product: DNA-binding transcriptional regulator Crl

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MTLTSAHPKSKLMKRFAALGPYLREGQCQNDHFFFDCLAVCINVKLAPEKREFWGWWIELEPSAGRFTYVYQLGLFNKEG
NWNAEKISDPEVQDKLESTLRSFHLRLEEMLASIDMKLEPAADFNDQPVKLSA

Sequences:

>Translated_133_residues
MTLTSAHPKSKLMKRFAALGPYLREGQCQNDHFFFDCLAVCINVKLAPEKREFWGWWIELEPSAGRFTYVYQLGLFNKEG
NWNAEKISDPEVQDKLESTLRSFHLRLEEMLASIDMKLEPAADFNDQPVKLSA
>Mature_132_residues
TLTSAHPKSKLMKRFAALGPYLREGQCQNDHFFFDCLAVCINVKLAPEKREFWGWWIELEPSAGRFTYVYQLGLFNKEGN
WNAEKISDPEVQDKLESTLRSFHLRLEEMLASIDMKLEPAADFNDQPVKLSA

Specific function: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the crl family [H]

Homologues:

Organism=Escherichia coli, GI1786435, Length=133, Percent_Identity=62.406015037594, Blast_Score=191, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009986 [H]

Pfam domain/function: PF07417 Crl [H]

EC number: NA

Molecular weight: Translated: 15386; Mature: 15255

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTSAHPKSKLMKRFAALGPYLREGQCQNDHFFFDCLAVCINVKLAPEKREFWGWWIEL
CCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEE
EPSAGRFTYVYQLGLFNKEGNWNAEKISDPEVQDKLESTLRSFHLRLEEMLASIDMKLEP
CCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AADFNDQPVKLSA
CCCCCCCCEEECC
>Mature Secondary Structure 
TLTSAHPKSKLMKRFAALGPYLREGQCQNDHFFFDCLAVCINVKLAPEKREFWGWWIEL
CCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEE
EPSAGRFTYVYQLGLFNKEGNWNAEKISDPEVQDKLESTLRSFHLRLEEMLASIDMKLEP
CCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AADFNDQPVKLSA
CCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA