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The map label for this gene is nqrA

Identifier: 51595237

GI number: 51595237

Start: 1071720

End: 1073063

Strand: Direct

Name: nqrA

Synonym: YPTB0887

Alternate gene names: 51595237

Gene position: 1071720-1073063 (Clockwise)

Preceding gene: 51595235

Following gene: 51595238

Centisome position: 22.59

GC content: 51.26

Gene sequence:

>1344_bases
ATGATTAAAATAAAGAAAGGGCTAGATCTTCCCATTGCTGGAGCCCCCGTTCAGACGATACAAGATGGTCCAGCGATTCA
TCATGTGGCCCTGCTCGGTGAAGAGTATGTTGGTATGCGTCCTTCAATGTTGGTGCAAGAAGGCGATCAGGTTAAAAAAG
GTCAGGCGCTGTTTGAAGACAAAAAGAATCCGGGCGTGTTGTTTACCGCCCCTGCCAGCGGCAAAATCAGTGCTATCAAT
CGTGGTGAGCGTCGAGTATTGCAATCGGTGGTGATTGAAGTTGAAGGTGATGAGCAAATCCCTTTCGAGCATTATGCTGC
TGAGGAGCTTAATCAACTGAGCGATGAGCAGGTTCAACACCATCTGTTGACGTCCGGTTTATGGACTGCGCTGCGGACTC
GCCCATTCAGTAAAACACCGGTTCCAGGCAGCCGTCCGCGCGCTATCTTTATCAGTGCGATGGATACCCAACCGTTGGCG
GCAGATCCGCAGGTTATTATTGCCACTGAATCAGAGGCGTTTAACCATGGCTTGACCGTATTGACGCGGCTGACGGACGG
TAAAGTACACGTCTGCCACGCGGCAGGGCAGGCTGTGACTCGTCATACCAATACGCAAGTGACTTACAACGAATTCTCCG
GGCCGCACCCTGCGGGTCTGGTGGGGACACATATTCATTTTCTTGAGCCAGTCAGCCAGACCAAAATGGTTTGGCATGTG
GGCTATCAGGATGTCATTGCTATCGGTAAATTGTTTACCCGTGGTGAGTTGTGTACTGACCGCATCGTCGCTTTGGCGGG
TCCACAGGTGAATCAACCCATTTTATTGCGTACTCGTTTAGGGGCCAGCTTATCTGAACTGACCGCCGGTAAACTAAAAG
AGGGTGATAACCGCATTATTTCAGGTTCAGTCCTCAGCGGTACCGCGTTCTCTGCTACCCATGGGTATCTGGGGCGTTTT
CATCAGCAAGTCTCCGTTATCCGCGAAGGGCGTGAAAAAGAGTTATTTGGTTGGGTGATGCCGGGGCGCGATAAATACTC
CATTACCCGCACGACGCTGGGCCACTTCTTCAAACGCAAATTGTTTGCTTTCTCGACTGATATGCACGGTGGTGAGCGTG
CCATGGTGCCAATTGGCAACTATGAGCGGGTCATGCCACTGGATATCCTGGCGACCCATCTGCTACGTGATTTATTGGCC
GGTGATACCGACAGCGCACAAGCACTCGGTTGTTTGGAGTTGGACGAAGAAGATCTGGCTTTGTGTACTTTTGTTTGTCC
CGGTAAGTACGAATACGGTCCGGTACTGCGCGACATACTGACCCAGATTGAGCAGGAAGGATAA

Upstream 100 bases:

>100_bases
GTCGCTTAATTGAACAGTGGAAATACCTCATCTTTACGTAGCTGTACGCTTCAGGGTTTATGTGCAGCATTTGATATCAC
TAATGAAGTCGTTTAAACCT

Downstream 100 bases:

>100_bases
CTGATGGGCCTGAAAAATTTTCTTGAGAAAATCGAACACCACTTTGAAGCGGGTGGGAAATTAGAAAAGTACTATCCGCT
GTACGAAGCTGCCGCAACCA

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MIKIKKGLDLPIAGAPVQTIQDGPAIHHVALLGEEYVGMRPSMLVQEGDQVKKGQALFEDKKNPGVLFTAPASGKISAIN
RGERRVLQSVVIEVEGDEQIPFEHYAAEELNQLSDEQVQHHLLTSGLWTALRTRPFSKTPVPGSRPRAIFISAMDTQPLA
ADPQVIIATESEAFNHGLTVLTRLTDGKVHVCHAAGQAVTRHTNTQVTYNEFSGPHPAGLVGTHIHFLEPVSQTKMVWHV
GYQDVIAIGKLFTRGELCTDRIVALAGPQVNQPILLRTRLGASLSELTAGKLKEGDNRIISGSVLSGTAFSATHGYLGRF
HQQVSVIREGREKELFGWVMPGRDKYSITRTTLGHFFKRKLFAFSTDMHGGERAMVPIGNYERVMPLDILATHLLRDLLA
GDTDSAQALGCLELDEEDLALCTFVCPGKYEYGPVLRDILTQIEQEG

Sequences:

>Translated_447_residues
MIKIKKGLDLPIAGAPVQTIQDGPAIHHVALLGEEYVGMRPSMLVQEGDQVKKGQALFEDKKNPGVLFTAPASGKISAIN
RGERRVLQSVVIEVEGDEQIPFEHYAAEELNQLSDEQVQHHLLTSGLWTALRTRPFSKTPVPGSRPRAIFISAMDTQPLA
ADPQVIIATESEAFNHGLTVLTRLTDGKVHVCHAAGQAVTRHTNTQVTYNEFSGPHPAGLVGTHIHFLEPVSQTKMVWHV
GYQDVIAIGKLFTRGELCTDRIVALAGPQVNQPILLRTRLGASLSELTAGKLKEGDNRIISGSVLSGTAFSATHGYLGRF
HQQVSVIREGREKELFGWVMPGRDKYSITRTTLGHFFKRKLFAFSTDMHGGERAMVPIGNYERVMPLDILATHLLRDLLA
GDTDSAQALGCLELDEEDLALCTFVCPGKYEYGPVLRDILTQIEQEG
>Mature_447_residues
MIKIKKGLDLPIAGAPVQTIQDGPAIHHVALLGEEYVGMRPSMLVQEGDQVKKGQALFEDKKNPGVLFTAPASGKISAIN
RGERRVLQSVVIEVEGDEQIPFEHYAAEELNQLSDEQVQHHLLTSGLWTALRTRPFSKTPVPGSRPRAIFISAMDTQPLA
ADPQVIIATESEAFNHGLTVLTRLTDGKVHVCHAAGQAVTRHTNTQVTYNEFSGPHPAGLVGTHIHFLEPVSQTKMVWHV
GYQDVIAIGKLFTRGELCTDRIVALAGPQVNQPILLRTRLGASLSELTAGKLKEGDNRIISGSVLSGTAFSATHGYLGRF
HQQVSVIREGREKELFGWVMPGRDKYSITRTTLGHFFKRKLFAFSTDMHGGERAMVPIGNYERVMPLDILATHLLRDLLA
GDTDSAQALGCLELDEEDLALCTFVCPGKYEYGPVLRDILTQIEQEG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 49017; Mature: 49017

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIKKGLDLPIAGAPVQTIQDGPAIHHVALLGEEYVGMRPSMLVQEGDQVKKGQALFED
CEEECCCCCCCCCCCCHHHHCCCCCEEEHEECCHHHCCCCCHHHHHCCCCHHCCCHHHHC
KKNPGVLFTAPASGKISAINRGERRVLQSVVIEVEGDEQIPFEHYAAEELNQLSDEQVQH
CCCCCEEEECCCCCCEEECCCHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
HLLTSGLWTALRTRPFSKTPVPGSRPRAIFISAMDTQPLAADPQVIIATESEAFNHGLTV
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCHHHCCEEE
LTRLTDGKVHVCHAAGQAVTRHTNTQVTYNEFSGPHPAGLVGTHIHFLEPVSQTKMVWHV
EEEECCCCEEEEECCCCHHHCCCCCEEEECCCCCCCCCCHHCCHHHHHCCCCCCEEEEEC
GYQDVIAIGKLFTRGELCTDRIVALAGPQVNQPILLRTRLGASLSELTAGKLKEGDNRII
CHHHHHHHHHHHHCCCHHHHHEEEECCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCEEE
SGSVLSGTAFSATHGYLGRFHQQVSVIREGREKELFGWVMPGRDKYSITRTTLGHFFKRK
ECCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHH
LFAFSTDMHGGERAMVPIGNYERVMPLDILATHLLRDLLAGDTDSAQALGCLELDEEDLA
HHHEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCCE
LCTFVCPGKYEYGPVLRDILTQIEQEG
EEEEECCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKIKKGLDLPIAGAPVQTIQDGPAIHHVALLGEEYVGMRPSMLVQEGDQVKKGQALFED
CEEECCCCCCCCCCCCHHHHCCCCCEEEHEECCHHHCCCCCHHHHHCCCCHHCCCHHHHC
KKNPGVLFTAPASGKISAINRGERRVLQSVVIEVEGDEQIPFEHYAAEELNQLSDEQVQH
CCCCCEEEECCCCCCEEECCCHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
HLLTSGLWTALRTRPFSKTPVPGSRPRAIFISAMDTQPLAADPQVIIATESEAFNHGLTV
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCHHHCCEEE
LTRLTDGKVHVCHAAGQAVTRHTNTQVTYNEFSGPHPAGLVGTHIHFLEPVSQTKMVWHV
EEEECCCCEEEEECCCCHHHCCCCCEEEECCCCCCCCCCHHCCHHHHHCCCCCCEEEEEC
GYQDVIAIGKLFTRGELCTDRIVALAGPQVNQPILLRTRLGASLSELTAGKLKEGDNRII
CHHHHHHHHHHHHCCCHHHHHEEEECCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCEEE
SGSVLSGTAFSATHGYLGRFHQQVSVIREGREKELFGWVMPGRDKYSITRTTLGHFFKRK
ECCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHH
LFAFSTDMHGGERAMVPIGNYERVMPLDILATHLLRDLLAGDTDSAQALGCLELDEEDLA
HHHEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCCCE
LCTFVCPGKYEYGPVLRDILTQIEQEG
EEEEECCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA