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The map label for this gene is clpB

Identifier: 51594998

GI number: 51594998

Start: 766349

End: 768952

Strand: Direct

Name: clpB

Synonym: YPTB0647

Alternate gene names: 51594998

Gene position: 766349-768952 (Clockwise)

Preceding gene: 51594997

Following gene: 51594999

Centisome position: 16.15

GC content: 53.34

Gene sequence:

>2604_bases
ATGGGAGCGATAACGGTGTATCAACGCGAACGTCTTTTTAATCGATTGGGCACTTTTGCCTATAAAACTTTTGTTGAAGC
CACCCGTCTTTGCCGCAGTTATCGGCATGAGTATGTGGAGCTTGAACATTGGTTAAAAATTCTCATGGATCAACAGCGTG
GGGACATTCCTGCTCTACTGACGCATTACGGACTGAGCCAAACGGTTATCTCCACGCAATTGGATCGCATTATTCAGCAT
ATGCCCGTCACCAAAGCATCGGTGCAGGATTTATCATCACGCTTGGAGTCCGTGGTCGAAGGCGGATTGGTGTTGAGCCA
ATTGATGGCGTCACCTTCTCCTATCCGTACCTCACATATTTTACTGGCACTATTACAGGATACCCAGCATCAGCGCTGGT
TATACCGCCTGTGCGATGAATTCAAAAAGCTGCCGGTCCCACAGGTTGCAGAGGAATATGAAGGCCTATTAGTTAACTCC
ATTGAACAGACCAGCGAGGTTCAAAGAGGCGACGCATTAGTGACGGAAACGGACAGCAGCTCATCAAAAGAAGCGCATGC
GGCATTGAACAAATGGTGTAACGACCTTACCCAGCAAGCCCGTGACGGTGAGATTGACCCCGTTATTGGTCGTGAAGCAG
AACTGCGTCAAGTGATTGATATTTTACTCCGTCGCCGTCAGAACAACCCTATTTTGGTTGGGGAAGCGGGGGTCGGTAAA
ACGGCGGTGGTTGAAGCGCTAGCGCGAAAACTGGCCAGTGGCGATGTCCCTCCGCTGTTGCAAGGGGCGCGTCTGCTTTC
TCTGGATTTGGGGAGGATGCAAGCCGGTGCCAGTATGCGCGGTGAATTTGAATCACGTCTTAAATCCCTGATCGATGGCA
TCAGCCAATCGGATACCCCGGTTATTCTGTTTTGTGATGAAGCCCATACGTTGGTGGGGGCAGGCGGGCAGGCGGGCACG
GGGGATGCGGTCAACCTGCTTAAACCGATGTTGGCGAGGGGCGCATTGCGCATGATCGCCGCCACCACCTGGTCAGAGTA
TAAACAGTTTATTGAACCTGACGCCGCGCTGACCCGGCGTTTCCAGCGGGTATTGATTGGCGAGCCAAACGAATCTACCG
CCGTCGATATGCTACGGGCGATTGCGCCACATTTTGCTCAACATCATAACGTCACTATCCGCGACGGTGCCATTCACGCG
GCGGTGCGCCTGTCATTACGCAACCTGCCTTCCCGGCAGTTGCCCGATAAAGCCATCAGTCTGCTCGACACCGCTTGCGC
GCGGGTCGCGCTCAGCCAATATGCCCAACCACAGGCGATTGAACAGTTATCGGCCCAACTGGATGTGCTTAAAACCGAGC
ATCAATATCTGGTACGGGAGAAGCAACTGGGCGAAGCGGTTGATCAACGGCTAGATGACGTTCAGACACAGATCCAAGCG
TTTGAACATGAACTAACCGCCTTGCAAAGCCGCCATCTGCATGAGCAACAGCTAGTGAGGGAGGTCCTGCCGGAGGGAGA
AGGCAGTGGCATGATGACGGAAAATGCCCGCTGGGGTGAACTGATGGCGTTACAGGAAGCGTCGCCACTGGTCTATCCAT
GGGTTGATGAGCAGAGCATCGCCGCGGTGCTTTCCGATTGGACCGGGATCCCGTCCGGCAAAATGTTGCAGGACGATATT
GAATGCGTCCTGAATCTTGAACAGCGTCTCGGTGATCATATTTTCGGGCAACGCAACGCTATCAAAGAGATTTCGCAGGC
GATACGTATTGCTCGGGCGGGCATCCAGTCTCAGGAGCGGCCACTCGGGATCTTCCTGCTGGCGGGGTCAACCGGTACGG
GCAAAACAGAAACGGCCAATGTACTGGTCGAAACCTTGTATGGCGGTGCTCATAACCTTATTACCTTCAATATGAGTGAG
TTCCAAGAGGCGCATACCTTATCCACGCTGAAAGGCGCACCTCCGGGCTATGTCGGCTATGGCAAGGGGGGGAAATTAAC
CGAAGCGGTAAGACGCAAACCTTATTCGGTCATCCTGCTTGATGAGTTTGATAAAGCTCACGCCGATATTCAGGACGCCT
TTTATCAGGTCTTCGACAAAGGGTGGATGGAAGATGCCGAAGGGCGTCGGGTCAGTTTCCGCCAGTGTTTCATCTTACTG
ACCTGTAATCAGGGCGCGGAAGAGATCGAACAGGCTTACCTCACCGCCAACGATATCAAACCCGGTGCATTAAAACCGTT
GGTATACGACGCCCTGTTGCGCCGCTTTGCGCCAGCGCTGTTAGCCAGGGTCAATATCATTCCTTATATCCCATTAGATC
AGGACGCTCTGGCACAGATCGCCTCTCATCATCTTGCGCGCTTACAAACGCGCCTGTGGGATGAAATTGGTGCCACTTTG
GTGACCGAGGGGGATATCCCCGGCTGGATCGCCTCACGGGTTTGCAGCCATCCGAACCATGGTCGTGCGGTGGAAGAACT
CTTGCGTCAAACCTTACTTCCCGCTGTTGGCAATGAAGTGTTGAAGCGTCGCCATGAGGCTGAACCGCTGAGAGAGATAC
GCCTGATTGTTGAGGAGACAGAACTGAGTATTGAGTTCGCGTAG

Upstream 100 bases:

>100_bases
TGGCTTGTCGTCTTGGCGGTGGAACGCTCAGCCGCCATAGCTGGTTAAAGCCAGGCTCAGCCTTGAGTATACAGCCAATT
TATAGAACGGTTACCTAGCT

Downstream 100 bases:

>100_bases
CTGATGTTTAGTCGACAACGGTTGTTGAGCTGAACGCTGTCGTTGGGCTGACAACTGACGTTTGGGCTGACGTGAGTACA
CATTTATTTTAAACGGGGCC

Product: ATP-dependent protease, Hsp 100, part of novel multi-chaperone system with DnaK, DnaJ, and GrpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 867; Mature: 866

Protein sequence:

>867_residues
MGAITVYQRERLFNRLGTFAYKTFVEATRLCRSYRHEYVELEHWLKILMDQQRGDIPALLTHYGLSQTVISTQLDRIIQH
MPVTKASVQDLSSRLESVVEGGLVLSQLMASPSPIRTSHILLALLQDTQHQRWLYRLCDEFKKLPVPQVAEEYEGLLVNS
IEQTSEVQRGDALVTETDSSSSKEAHAALNKWCNDLTQQARDGEIDPVIGREAELRQVIDILLRRRQNNPILVGEAGVGK
TAVVEALARKLASGDVPPLLQGARLLSLDLGRMQAGASMRGEFESRLKSLIDGISQSDTPVILFCDEAHTLVGAGGQAGT
GDAVNLLKPMLARGALRMIAATTWSEYKQFIEPDAALTRRFQRVLIGEPNESTAVDMLRAIAPHFAQHHNVTIRDGAIHA
AVRLSLRNLPSRQLPDKAISLLDTACARVALSQYAQPQAIEQLSAQLDVLKTEHQYLVREKQLGEAVDQRLDDVQTQIQA
FEHELTALQSRHLHEQQLVREVLPEGEGSGMMTENARWGELMALQEASPLVYPWVDEQSIAAVLSDWTGIPSGKMLQDDI
ECVLNLEQRLGDHIFGQRNAIKEISQAIRIARAGIQSQERPLGIFLLAGSTGTGKTETANVLVETLYGGAHNLITFNMSE
FQEAHTLSTLKGAPPGYVGYGKGGKLTEAVRRKPYSVILLDEFDKAHADIQDAFYQVFDKGWMEDAEGRRVSFRQCFILL
TCNQGAEEIEQAYLTANDIKPGALKPLVYDALLRRFAPALLARVNIIPYIPLDQDALAQIASHHLARLQTRLWDEIGATL
VTEGDIPGWIASRVCSHPNHGRAVEELLRQTLLPAVGNEVLKRRHEAEPLREIRLIVEETELSIEFA

Sequences:

>Translated_867_residues
MGAITVYQRERLFNRLGTFAYKTFVEATRLCRSYRHEYVELEHWLKILMDQQRGDIPALLTHYGLSQTVISTQLDRIIQH
MPVTKASVQDLSSRLESVVEGGLVLSQLMASPSPIRTSHILLALLQDTQHQRWLYRLCDEFKKLPVPQVAEEYEGLLVNS
IEQTSEVQRGDALVTETDSSSSKEAHAALNKWCNDLTQQARDGEIDPVIGREAELRQVIDILLRRRQNNPILVGEAGVGK
TAVVEALARKLASGDVPPLLQGARLLSLDLGRMQAGASMRGEFESRLKSLIDGISQSDTPVILFCDEAHTLVGAGGQAGT
GDAVNLLKPMLARGALRMIAATTWSEYKQFIEPDAALTRRFQRVLIGEPNESTAVDMLRAIAPHFAQHHNVTIRDGAIHA
AVRLSLRNLPSRQLPDKAISLLDTACARVALSQYAQPQAIEQLSAQLDVLKTEHQYLVREKQLGEAVDQRLDDVQTQIQA
FEHELTALQSRHLHEQQLVREVLPEGEGSGMMTENARWGELMALQEASPLVYPWVDEQSIAAVLSDWTGIPSGKMLQDDI
ECVLNLEQRLGDHIFGQRNAIKEISQAIRIARAGIQSQERPLGIFLLAGSTGTGKTETANVLVETLYGGAHNLITFNMSE
FQEAHTLSTLKGAPPGYVGYGKGGKLTEAVRRKPYSVILLDEFDKAHADIQDAFYQVFDKGWMEDAEGRRVSFRQCFILL
TCNQGAEEIEQAYLTANDIKPGALKPLVYDALLRRFAPALLARVNIIPYIPLDQDALAQIASHHLARLQTRLWDEIGATL
VTEGDIPGWIASRVCSHPNHGRAVEELLRQTLLPAVGNEVLKRRHEAEPLREIRLIVEETELSIEFA
>Mature_866_residues
GAITVYQRERLFNRLGTFAYKTFVEATRLCRSYRHEYVELEHWLKILMDQQRGDIPALLTHYGLSQTVISTQLDRIIQHM
PVTKASVQDLSSRLESVVEGGLVLSQLMASPSPIRTSHILLALLQDTQHQRWLYRLCDEFKKLPVPQVAEEYEGLLVNSI
EQTSEVQRGDALVTETDSSSSKEAHAALNKWCNDLTQQARDGEIDPVIGREAELRQVIDILLRRRQNNPILVGEAGVGKT
AVVEALARKLASGDVPPLLQGARLLSLDLGRMQAGASMRGEFESRLKSLIDGISQSDTPVILFCDEAHTLVGAGGQAGTG
DAVNLLKPMLARGALRMIAATTWSEYKQFIEPDAALTRRFQRVLIGEPNESTAVDMLRAIAPHFAQHHNVTIRDGAIHAA
VRLSLRNLPSRQLPDKAISLLDTACARVALSQYAQPQAIEQLSAQLDVLKTEHQYLVREKQLGEAVDQRLDDVQTQIQAF
EHELTALQSRHLHEQQLVREVLPEGEGSGMMTENARWGELMALQEASPLVYPWVDEQSIAAVLSDWTGIPSGKMLQDDIE
CVLNLEQRLGDHIFGQRNAIKEISQAIRIARAGIQSQERPLGIFLLAGSTGTGKTETANVLVETLYGGAHNLITFNMSEF
QEAHTLSTLKGAPPGYVGYGKGGKLTEAVRRKPYSVILLDEFDKAHADIQDAFYQVFDKGWMEDAEGRRVSFRQCFILLT
CNQGAEEIEQAYLTANDIKPGALKPLVYDALLRRFAPALLARVNIIPYIPLDQDALAQIASHHLARLQTRLWDEIGATLV
TEGDIPGWIASRVCSHPNHGRAVEELLRQTLLPAVGNEVLKRRHEAEPLREIRLIVEETELSIEFA

Specific function: Required for secretion of hcp1 probably by providing the energy source for its translocation [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=312, Percent_Identity=31.4102564102564, Blast_Score=142, Evalue=1e-33,
Organism=Escherichia coli, GI1788943, Length=809, Percent_Identity=36.2175525339926, Blast_Score=487, Evalue=1e-138,
Organism=Escherichia coli, GI1787109, Length=413, Percent_Identity=35.1089588377724, Blast_Score=231, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6320464, Length=719, Percent_Identity=36.5785813630042, Blast_Score=439, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6323002, Length=807, Percent_Identity=31.9702602230483, Blast_Score=404, Evalue=1e-113,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR017729
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96448; Mature: 96317

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAITVYQRERLFNRLGTFAYKTFVEATRLCRSYRHEYVELEHWLKILMDQQRGDIPALL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
THYGLSQTVISTQLDRIIQHMPVTKASVQDLSSRLESVVEGGLVLSQLMASPSPIRTSHI
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LLALLQDTQHQRWLYRLCDEFKKLPVPQVAEEYEGLLVNSIEQTSEVQRGDALVTETDSS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCC
SSKEAHAALNKWCNDLTQQARDGEIDPVIGREAELRQVIDILLRRRQNNPILVGEAGVGK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCH
TAVVEALARKLASGDVPPLLQGARLLSLDLGRMQAGASMRGEFESRLKSLIDGISQSDTP
HHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
VILFCDEAHTLVGAGGQAGTGDAVNLLKPMLARGALRMIAATTWSEYKQFIEPDAALTRR
EEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FQRVLIGEPNESTAVDMLRAIAPHFAQHHNVTIRDGAIHAAVRLSLRNLPSRQLPDKAIS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHH
LLDTACARVALSQYAQPQAIEQLSAQLDVLKTEHQYLVREKQLGEAVDQRLDDVQTQIQA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEHELTALQSRHLHEQQLVREVLPEGEGSGMMTENARWGELMALQEASPLVYPWVDEQSI
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCHHH
AAVLSDWTGIPSGKMLQDDIECVLNLEQRLGDHIFGQRNAIKEISQAIRIARAGIQSQER
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
PLGIFLLAGSTGTGKTETANVLVETLYGGAHNLITFNMSEFQEAHTLSTLKGAPPGYVGY
CCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCC
GKGGKLTEAVRRKPYSVILLDEFDKAHADIQDAFYQVFDKGWMEDAEGRRVSFRQCFILL
CCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEE
TCNQGAEEIEQAYLTANDIKPGALKPLVYDALLRRFAPALLARVNIIPYIPLDQDALAQI
ECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ASHHLARLQTRLWDEIGATLVTEGDIPGWIASRVCSHPNHGRAVEELLRQTLLPAVGNEV
HHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LKRRHEAEPLREIRLIVEETELSIEFA
HHHHHCCCHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure 
GAITVYQRERLFNRLGTFAYKTFVEATRLCRSYRHEYVELEHWLKILMDQQRGDIPALL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
THYGLSQTVISTQLDRIIQHMPVTKASVQDLSSRLESVVEGGLVLSQLMASPSPIRTSHI
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LLALLQDTQHQRWLYRLCDEFKKLPVPQVAEEYEGLLVNSIEQTSEVQRGDALVTETDSS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCC
SSKEAHAALNKWCNDLTQQARDGEIDPVIGREAELRQVIDILLRRRQNNPILVGEAGVGK
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCH
TAVVEALARKLASGDVPPLLQGARLLSLDLGRMQAGASMRGEFESRLKSLIDGISQSDTP
HHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
VILFCDEAHTLVGAGGQAGTGDAVNLLKPMLARGALRMIAATTWSEYKQFIEPDAALTRR
EEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FQRVLIGEPNESTAVDMLRAIAPHFAQHHNVTIRDGAIHAAVRLSLRNLPSRQLPDKAIS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHCCCCCCCCHHHHH
LLDTACARVALSQYAQPQAIEQLSAQLDVLKTEHQYLVREKQLGEAVDQRLDDVQTQIQA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEHELTALQSRHLHEQQLVREVLPEGEGSGMMTENARWGELMALQEASPLVYPWVDEQSI
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCHHH
AAVLSDWTGIPSGKMLQDDIECVLNLEQRLGDHIFGQRNAIKEISQAIRIARAGIQSQER
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
PLGIFLLAGSTGTGKTETANVLVETLYGGAHNLITFNMSEFQEAHTLSTLKGAPPGYVGY
CCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCC
GKGGKLTEAVRRKPYSVILLDEFDKAHADIQDAFYQVFDKGWMEDAEGRRVSFRQCFILL
CCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEE
TCNQGAEEIEQAYLTANDIKPGALKPLVYDALLRRFAPALLARVNIIPYIPLDQDALAQI
ECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ASHHLARLQTRLWDEIGATLVTEGDIPGWIASRVCSHPNHGRAVEELLRQTLLPAVGNEV
HHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LKRRHEAEPLREIRLIVEETELSIEFA
HHHHHCCCHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]