Click here to switch to the map view.

The map label for this gene is lcrF [H]

Identifier: 51594670

GI number: 51594670

Start: 383934

End: 384713

Strand: Direct

Name: lcrF [H]

Synonym: YPTB0315

Alternate gene names: 51594670

Gene position: 383934-384713 (Clockwise)

Preceding gene: 51594669

Following gene: 51594671

Centisome position: 8.09

GC content: 41.28

Gene sequence:

>780_bases
GTGAATACCGGATACGCATTGGCAGTATTATTGGTCAAACTGCATAAGATTAATTGTTCCCTAAGGAATATCATGAAGTC
AATACAGTTTATTTTATTTCGGCAAGAGGGCGTATTACGCAGTGATGGCGAGCGCTATGTTATACCTGCGGGAAAATTAG
TGATTGCCGATGAGCAGGCCAGTGCCTCTGCGTTTGCAAACAGTGCCATCACCTCTATATTATGTTACCCAATAGATCTT
TTTCCGATATATCAGGATTTAGCCAGAAGAACATTACCGTTGAATAAAGGCCATCTTCCTCATGCGGTAAATGATAAATA
TAAAGTGTTGCCAGCGAATGTTGAAATTATACAAGCTGCTGAAGAATTAATTAATATAGAGCGTGTTGCCTCTCTGCGAT
TTCTTTATCTTTATTGTTTAGGTATCGATAACGTTTATTTTTCCAAGCTGTTGGACTCCATTGTGGGTACGAATAACGAA
CTACTTGAGTTTTTCGAAAAGAATCGGCTCAACCCATGGAGCGTTTCACGCTATGCCAATGAATTGGGTATTTCGACCCG
GAAATTGAATTTCCTGTTTTATGAGAAATTCGGCATGTCGGCGAAACAGTGGTTACTGGATCAGCGTTTGAAAAAGGGCT
GTGAGCTATTACTTTCGACCCGCTTACGGGTGGCTGATATTGCCATGGAGTGTGGTTTTAGTAATCACGCGCATTTCTCA
GATAGCTTTCGTCGGCGCTTTCAACAATGCCCATCGCATATGCGTTCACTTATTGAATAG

Upstream 100 bases:

>100_bases
TTGGCCTTGCAACGTGCAGAAGAAATAATAGAAATACTGACGTTGCGCTATGGGAATAAAGAATAAAGTGATGTTTACTG
TCTGATTATTCAGACTTCAG

Downstream 100 bases:

>100_bases
GAGAGTTTGATGCAGATAAGTAGCCCAATGGGCCAATTGACAAACGATATTCAGCAGGCCAGACAGGCGTATCAGAACCA
AATGGCGGCAGTGAATATCA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MNTGYALAVLLVKLHKINCSLRNIMKSIQFILFRQEGVLRSDGERYVIPAGKLVIADEQASASAFANSAITSILCYPIDL
FPIYQDLARRTLPLNKGHLPHAVNDKYKVLPANVEIIQAAEELINIERVASLRFLYLYCLGIDNVYFSKLLDSIVGTNNE
LLEFFEKNRLNPWSVSRYANELGISTRKLNFLFYEKFGMSAKQWLLDQRLKKGCELLLSTRLRVADIAMECGFSNHAHFS
DSFRRRFQQCPSHMRSLIE

Sequences:

>Translated_259_residues
MNTGYALAVLLVKLHKINCSLRNIMKSIQFILFRQEGVLRSDGERYVIPAGKLVIADEQASASAFANSAITSILCYPIDL
FPIYQDLARRTLPLNKGHLPHAVNDKYKVLPANVEIIQAAEELINIERVASLRFLYLYCLGIDNVYFSKLLDSIVGTNNE
LLEFFEKNRLNPWSVSRYANELGISTRKLNFLFYEKFGMSAKQWLLDQRLKKGCELLLSTRLRVADIAMECGFSNHAHFS
DSFRRRFQQCPSHMRSLIE
>Mature_259_residues
MNTGYALAVLLVKLHKINCSLRNIMKSIQFILFRQEGVLRSDGERYVIPAGKLVIADEQASASAFANSAITSILCYPIDL
FPIYQDLARRTLPLNKGHLPHAVNDKYKVLPANVEIIQAAEELINIERVASLRFLYLYCLGIDNVYFSKLLDSIVGTNNE
LLEFFEKNRLNPWSVSRYANELGISTRKLNFLFYEKFGMSAKQWLLDQRLKKGCELLLSTRLRVADIAMECGFSNHAHFS
DSFRRRFQQCPSHMRSLIE

Specific function: Transcriptional activator of the thermally regulated virulent yopE gene. LcrF activity could be modulated by the interaction with an inducer molecule serving as a temperature messenger. The availability of the messenger would in turn be controlled by a te

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 29687; Mature: 29687

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTGYALAVLLVKLHKINCSLRNIMKSIQFILFRQEGVLRSDGERYVIPAGKLVIADEQA
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEECCCH
SASAFANSAITSILCYPIDLFPIYQDLARRTLPLNKGHLPHAVNDKYKVLPANVEIIQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHHHHHH
EELINIERVASLRFLYLYCLGIDNVYFSKLLDSIVGTNNELLEFFEKNRLNPWSVSRYAN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
ELGISTRKLNFLFYEKFGMSAKQWLLDQRLKKGCELLLSTRLRVADIAMECGFSNHAHFS
HHCCCHHHHHEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DSFRRRFQQCPSHMRSLIE
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTGYALAVLLVKLHKINCSLRNIMKSIQFILFRQEGVLRSDGERYVIPAGKLVIADEQA
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEECCCH
SASAFANSAITSILCYPIDLFPIYQDLARRTLPLNKGHLPHAVNDKYKVLPANVEIIQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHHHHHH
EELINIERVASLRFLYLYCLGIDNVYFSKLLDSIVGTNNELLEFFEKNRLNPWSVSRYAN
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
ELGISTRKLNFLFYEKFGMSAKQWLLDQRLKKGCELLLSTRLRVADIAMECGFSNHAHFS
HHCCCHHHHHEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DSFRRRFQQCPSHMRSLIE
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624422; 9746557; 9748454; 11586360 [H]