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The map label for this gene is thiS

Identifier: 51594642

GI number: 51594642

Start: 346773

End: 346988

Strand: Reverse

Name: thiS

Synonym: YPTB0287

Alternate gene names: 51594642

Gene position: 346988-346773 (Counterclockwise)

Preceding gene: 51594643

Following gene: 51594641

Centisome position: 7.31

GC content: 50.0

Gene sequence:

>216_bases
GTGAAGACCAATTACATACCAATCATGCTCAATGACCAGCCATTAGAGGTGGAGTGCAATCTCACCGCCGAGATGCTGCT
TAATCAGCTTAAACACCACCAGCCGGGAACCGCACTGGCTATTAATCAGGTCATTATTCCGCGCGCCGATTGGCAAAATC
ATCGGTTGCAAGCGGGTGATCATATTTTGCTGTTCCAAGCCATTGCCGGAGGCTGA

Upstream 100 bases:

>100_bases
CACTGAGCGGTAAATTGCGGCTATTTGATGGCAAACAGCAGAGTTGGAGCACCCTGCAACTGACAAGGGCAGCCCATTGC
CCGGCGTGTGGAGGTGGGTT

Downstream 100 bases:

>100_bases
CATGCTGAAAATTGCCGATACCACTTTTACTTCTCGTTTATTTACGGGCACAGGGAAGTTCTCCTCTCCCGAACTGATGC
TGGAAGCACTCCGCGCCTCG

Product: sulfur carrier protein ThiS

Products: NA

Alternate protein names: Thiamine biosynthesis protein ThiS [H]

Number of amino acids: Translated: 71; Mature: 71

Protein sequence:

>71_residues
MKTNYIPIMLNDQPLEVECNLTAEMLLNQLKHHQPGTALAINQVIIPRADWQNHRLQAGDHILLFQAIAGG

Sequences:

>Translated_71_residues
MKTNYIPIMLNDQPLEVECNLTAEMLLNQLKHHQPGTALAINQVIIPRADWQNHRLQAGDHILLFQAIAGG
>Mature_71_residues
MKTNYIPIMLNDQPLEVECNLTAEMLLNQLKHHQPGTALAINQVIIPRADWQNHRLQAGDHILLFQAIAGG

Specific function: Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate [H]

COG id: COG2104

COG function: function code H; Sulfur transfer protein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfur carrier protein ThiS family [H]

Homologues:

Organism=Escherichia coli, GI48994994, Length=66, Percent_Identity=51.5151515151515, Blast_Score=69, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR016155
- InterPro:   IPR010035
- InterPro:   IPR003749 [H]

Pfam domain/function: PF02597 ThiS [H]

EC number: NA

Molecular weight: Translated: 7982; Mature: 7982

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNYIPIMLNDQPLEVECNLTAEMLLNQLKHHQPGTALAINQVIIPRADWQNHRLQAGD
CCCCEEEEEECCCCEEEEECCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCEECCCC
HILLFQAIAGG
EEEEEEEECCC
>Mature Secondary Structure
MKTNYIPIMLNDQPLEVECNLTAEMLLNQLKHHQPGTALAINQVIIPRADWQNHRLQAGD
CCCCEEEEEECCCCEEEEECCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCEECCCC
HILLFQAIAGG
EEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432721; 8265357; 9278503; 9632726; 10082377 [H]