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The map label for this gene is rbsK [H]

Identifier: 51594367

GI number: 51594367

Start: 8350

End: 9276

Strand: Direct

Name: rbsK [H]

Synonym: YPTB0008

Alternate gene names: 51594367

Gene position: 8350-9276 (Clockwise)

Preceding gene: 51594366

Following gene: 51594368

Centisome position: 0.18

GC content: 50.05

Gene sequence:

>927_bases
ATGGAAACAGGTAAGCTGGTGGTGTTGGGCAGTATCAATGCCGACCATATTCTGAATATTGAGCAGTTTCCACGTCCGGG
TGAAACGGTGATCGGGCAGCAGTATAACGTTGCTTTCGGAGGTAAAGGGGCTAATCAAGCGGTTGCTGCTGGCCGTAGCG
GTGCGGATATCGCATTTATTGCCTGTGTGGGTGACGATGATATTGGTGAACGGGTGCGTCAGCAACTCACTGCCGATAAG
ATTGATACTCAGCCTATCGAGGCTATTAAGGGGGCAACTACCGGTGTGGCATTGATCTTCGTGAATAGCGATGGCGAAAA
TGTGATTGGTATTAATGCGGGGGCTAACTCAGCGGTGACACCAGAGTATCTTCGCCGCTACCAACAACAAGTGATCGATG
CTGATGCACTCTTAATGCAACTGGAGTCGCCGCTCGACACTGTTATTGCGGCCGCTAAACTGGCGAAGCAGCATCAAACT
CAGGTTATCCTCAATCCGGCACCCGCCCGTAAATTACCCGATGAATTATTAACTCTGGTCGATATGATTACGCCTAATGA
AACGGAAGCCGAGCGTTTGACCGGCATTCATATTGAGCAGGATGATGATGCCGCGAAAGCAGCGCAAATTTTGCATGATA
AAGGCATTGCTACCGTGATCATCACCTTAGGTAGTCGTGGCGTATGGCTCAGTGAACAAGGTAAAGGTAAATTAGTGGCG
GGGTTCAAGGTAAATGCCGTAGATACCATTGCTGCCGGTGATACGTTTAACGGTGCATTATTGACAGCGTTATTAGAAGG
CCAGTCTATGGATGCCGCAGTGCGTTTTGCTCATGCCGCGGCGGCTATTGCGGTCACTCGGCCTGGAGCACAGCCGTCCA
TTCCATGGCGTGCCGAAATTGATAGCTTCTTACAAGAACGAGTGTAA

Upstream 100 bases:

>100_bases
AGTGTTCTCCCTTTGCTAATATCATTCTCGGCTCCGGCGTAACCTTCTAAGGCCTTTATGCAACCTTTACTAAAATTTCA
AGGACAAAGGAATAAATAAG

Downstream 100 bases:

>100_bases
AACGTGGCCACAATGAAAGATGTCGCCCGTCTGGCAGGGGTATCGTCAGGCAATGGCACGTGCAGGTTTGCCAATTATTG
CCGGGTATGAAGTTGTCAGT

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
METGKLVVLGSINADHILNIEQFPRPGETVIGQQYNVAFGGKGANQAVAAGRSGADIAFIACVGDDDIGERVRQQLTADK
IDTQPIEAIKGATTGVALIFVNSDGENVIGINAGANSAVTPEYLRRYQQQVIDADALLMQLESPLDTVIAAAKLAKQHQT
QVILNPAPARKLPDELLTLVDMITPNETEAERLTGIHIEQDDDAAKAAQILHDKGIATVIITLGSRGVWLSEQGKGKLVA
GFKVNAVDTIAAGDTFNGALLTALLEGQSMDAAVRFAHAAAAIAVTRPGAQPSIPWRAEIDSFLQERV

Sequences:

>Translated_308_residues
METGKLVVLGSINADHILNIEQFPRPGETVIGQQYNVAFGGKGANQAVAAGRSGADIAFIACVGDDDIGERVRQQLTADK
IDTQPIEAIKGATTGVALIFVNSDGENVIGINAGANSAVTPEYLRRYQQQVIDADALLMQLESPLDTVIAAAKLAKQHQT
QVILNPAPARKLPDELLTLVDMITPNETEAERLTGIHIEQDDDAAKAAQILHDKGIATVIITLGSRGVWLSEQGKGKLVA
GFKVNAVDTIAAGDTFNGALLTALLEGQSMDAAVRFAHAAAAIAVTRPGAQPSIPWRAEIDSFLQERV
>Mature_308_residues
METGKLVVLGSINADHILNIEQFPRPGETVIGQQYNVAFGGKGANQAVAAGRSGADIAFIACVGDDDIGERVRQQLTADK
IDTQPIEAIKGATTGVALIFVNSDGENVIGINAGANSAVTPEYLRRYQQQVIDADALLMQLESPLDTVIAAAKLAKQHQT
QVILNPAPARKLPDELLTLVDMITPNETEAERLTGIHIEQDDDAAKAAQILHDKGIATVIITLGSRGVWLSEQGKGKLVA
GFKVNAVDTIAAGDTFNGALLTALLEGQSMDAAVRFAHAAAAIAVTRPGAQPSIPWRAEIDSFLQERV

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=37.1621621621622, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=72.0930232558139, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI87082343, Length=304, Percent_Identity=31.9078947368421, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081971, Length=306, Percent_Identity=26.1437908496732, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788491, Length=251, Percent_Identity=25.0996015936255, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788484, Length=286, Percent_Identity=26.2237762237762, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17532905, Length=299, Percent_Identity=39.4648829431438, Blast_Score=181, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6319884, Length=327, Percent_Identity=29.3577981651376, Blast_Score=125, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24583886, Length=307, Percent_Identity=32.2475570032573, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI20128807, Length=309, Percent_Identity=34.9514563106796, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32528; Mature: 32528

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METGKLVVLGSINADHILNIEQFPRPGETVIGQQYNVAFGGKGANQAVAAGRSGADIAFI
CCCCCEEEEECCCCCCEECHHHCCCCCCHHCCCEEEEEECCCCCCHHHHCCCCCCCEEEE
ACVGDDDIGERVRQQLTADKIDTQPIEAIKGATTGVALIFVNSDGENVIGINAGANSAVT
EEECCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCC
PEYLRRYQQQVIDADALLMQLESPLDTVIAAAKLAKQHQTQVILNPAPARKLPDELLTLV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHH
DMITPNETEAERLTGIHIEQDDDAAKAAQILHDKGIATVIITLGSRGVWLSEQGKGKLVA
HHCCCCCCCHHHHEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCEEECCCCCCCEEE
GFKVNAVDTIAAGDTFNGALLTALLEGQSMDAAVRFAHAAAAIAVTRPGAQPSIPWRAEI
EEEECCEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHEEEEEECCCCCCCCCHHHHH
DSFLQERV
HHHHHHCC
>Mature Secondary Structure
METGKLVVLGSINADHILNIEQFPRPGETVIGQQYNVAFGGKGANQAVAAGRSGADIAFI
CCCCCEEEEECCCCCCEECHHHCCCCCCHHCCCEEEEEECCCCCCHHHHCCCCCCCEEEE
ACVGDDDIGERVRQQLTADKIDTQPIEAIKGATTGVALIFVNSDGENVIGINAGANSAVT
EEECCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCC
PEYLRRYQQQVIDADALLMQLESPLDTVIAAAKLAKQHQTQVILNPAPARKLPDELLTLV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHH
DMITPNETEAERLTGIHIEQDDDAAKAAQILHDKGIATVIITLGSRGVWLSEQGKGKLVA
HHCCCCCCCHHHHEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCEEECCCCCCCEEE
GFKVNAVDTIAAGDTFNGALLTALLEGQSMDAAVRFAHAAAAIAVTRPGAQPSIPWRAEI
EEEECCEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHEEEEEECCCCCCCCCHHHHH
DSFLQERV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]