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The map label for this gene is yfbT [H]

Identifier: 161760567

GI number: 161760567

Start: 3069069

End: 3069725

Strand: Reverse

Name: yfbT [H]

Synonym: YPTB2593

Alternate gene names: 161760567

Gene position: 3069725-3069069 (Counterclockwise)

Preceding gene: 51596913

Following gene: 51596911

Centisome position: 64.7

GC content: 52.21

Gene sequence:

>657_bases
GTGGAGTGTAAAGGTTTTCTTTTTGATTTAGATGGGACGTTGGTTGATTCACTACCTGTTGTTGAACGTGCCTGGATTGG
CTGGGCGCAACGTCGAGGCGTTAATCCATCAAAAGTTCTGGATTTTATTCATGGTAAACAAGCGATTACCTCTTTGCGTC
ATTTTATGCCGGGTGCCAGTGAAGCTGAAATTCAGGACGAGTTTCTGGCATTAGAGCAAATTGAAGCCAATGATACGGAG
GGGGTAACTGCGCTACCAGGGGCGGTGGCACTGTTGACCCGGTTGAATGAACTGGCTATTCCGTGGGCGATAGTGACTTC
AGGTTCGATACCTGTTGCCTCAGCTCGCCGGGCGGCAGGTTGTTTGCCAGAGCCGAAAGTGTTTGTGACCGCCGAATTGG
TGAAGCAGGGTAAACCTGCGCCCGATGCCTATTTATTAGGGGCCGAACGTTTAGGCCTTGCCCCTGCGGATTGTATTGTG
GTGGAAGATGCCCCCGCCGGGATCCTTTCGGGGCTAGCGGCCGGTTGTCAGGTGATCGCGGTTAATGCACCAACAGATAC
CCCAAAACTCGATCAGGTTGATCTGGTGCTTCACTCACTGGAGCAATTGGTGGTAGACGCCACTGCTCATGGTGCGGTGG
TTCGGTTACTGCCTTAA

Upstream 100 bases:

>100_bases
AGGTCGATGCTGTTCTGGTTCACGATACAAATAATATTGCCCCGCCGATTGATATCCAACGTCAACCGCGAGGGGAGAGA
GGCTTTAAGGGGATGTGCTT

Downstream 100 bases:

>100_bases
TCTGCATGGCGGCTAACGGTATCCCGTTACAGGTGCTGTCGTAGGGTGATAAGCCAATAGTAGGGTGCCTCGACGGCACC
TTTTTTGTATCGTTAAAGAG

Product: phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MECKGFLFDLDGTLVDSLPVVERAWIGWAQRRGVNPSKVLDFIHGKQAITSLRHFMPGASEAEIQDEFLALEQIEANDTE
GVTALPGAVALLTRLNELAIPWAIVTSGSIPVASARRAAGCLPEPKVFVTAELVKQGKPAPDAYLLGAERLGLAPADCIV
VEDAPAGILSGLAAGCQVIAVNAPTDTPKLDQVDLVLHSLEQLVVDATAHGAVVRLLP

Sequences:

>Translated_218_residues
MECKGFLFDLDGTLVDSLPVVERAWIGWAQRRGVNPSKVLDFIHGKQAITSLRHFMPGASEAEIQDEFLALEQIEANDTE
GVTALPGAVALLTRLNELAIPWAIVTSGSIPVASARRAAGCLPEPKVFVTAELVKQGKPAPDAYLLGAERLGLAPADCIV
VEDAPAGILSGLAAGCQVIAVNAPTDTPKLDQVDLVLHSLEQLVVDATAHGAVVRLLP
>Mature_218_residues
MECKGFLFDLDGTLVDSLPVVERAWIGWAQRRGVNPSKVLDFIHGKQAITSLRHFMPGASEAEIQDEFLALEQIEANDTE
GVTALPGAVALLTRLNELAIPWAIVTSGSIPVASARRAAGCLPEPKVFVTAELVKQGKPAPDAYLLGAERLGLAPADCIV
VEDAPAGILSGLAAGCQVIAVNAPTDTPKLDQVDLVLHSLEQLVVDATAHGAVVRLLP

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrate glucose 6-phosphate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI87082080, Length=214, Percent_Identity=71.9626168224299, Blast_Score=298, Evalue=1e-82,
Organism=Escherichia coli, GI1789046, Length=189, Percent_Identity=30.6878306878307, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321834, Length=231, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321833, Length=231, Percent_Identity=32.034632034632, Blast_Score=93, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320905, Length=210, Percent_Identity=32.3809523809524, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322136, Length=210, Percent_Identity=30.952380952381, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129151, Length=201, Percent_Identity=33.8308457711443, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17137324, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 22954; Mature: 22954

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MECKGFLFDLDGTLVDSLPVVERAWIGWAQRRGVNPSKVLDFIHGKQAITSLRHFMPGAS
CCCCCEEEECCCCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
EAEIQDEFLALEQIEANDTEGVTALPGAVALLTRLNELAIPWAIVTSGSIPVASARRAAG
CHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHC
CLPEPKVFVTAELVKQGKPAPDAYLLGAERLGLAPADCIVVEDAPAGILSGLAAGCQVIA
CCCCCCEEEEHHHHHCCCCCCCCEEECHHHCCCCCCCEEEECCCCHHHHHHHHCCCEEEE
VNAPTDTPKLDQVDLVLHSLEQLVVDATAHGAVVRLLP
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure
MECKGFLFDLDGTLVDSLPVVERAWIGWAQRRGVNPSKVLDFIHGKQAITSLRHFMPGAS
CCCCCEEEECCCCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
EAEIQDEFLALEQIEANDTEGVTALPGAVALLTRLNELAIPWAIVTSGSIPVASARRAAG
CHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHC
CLPEPKVFVTAELVKQGKPAPDAYLLGAERLGLAPADCIVVEDAPAGILSGLAAGCQVIA
CCCCCCEEEEHHHHHCCCCCCCCEEECHHHCCCCCCCEEEECCCCHHHHHHHHCCCEEEE
VNAPTDTPKLDQVDLVLHSLEQLVVDATAHGAVVRLLP
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 10493123 [H]