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The map label for this gene is galK [H]

Identifier: 50843724

GI number: 50843724

Start: 2482666

End: 2483856

Strand: Reverse

Name: galK [H]

Synonym: PPA2287

Alternate gene names: 50843724

Gene position: 2483856-2482666 (Counterclockwise)

Preceding gene: 50843725

Following gene: 50843723

Centisome position: 97.02

GC content: 60.79

Gene sequence:

>1191_bases
GTGACACGCTGGTTCGTTCCGGGACGGATAGAGGTTCTCGGCAAGCACACTGACTACGCTGGCGGGTCCACACTGGTGGC
CGCCGTGGATCGCGGGGTGACGATTTCAATCGAGCCGGGTGACAGTGGGATAACGGTGTCGACGGACGCCGCTCCCGGTG
AGCTGTCCTTAGCCGCGGGTCATGATCCAAAATTGCCGGCTGGTCACTGGGGTAGGTACGCACAAGCCGTTGTTGACCGT
TTGGCGGCAAATTTCGGTGATTTGGCCCCCGCCAGGATTCGGCTCACTTCTGACCTGCCGTTAGCCAGTGGGATGAGTTC
TTCCTCTGCCCTCGTCAGCGCGATCGTGTTGGGCCTGGCTGATTTCAATGGGCTGCCTGATACCCGCACCTGGCAGGACA
ACATCACCGACGATGCCGATCTGGCTGGGTATCTGGCCTGTCATGAGAACGGTATGACTTTCAAGAACCTGGTAGGGGCC
GCAGGTGTGGGCACTTTTGGCGGTTCAGAGGACCACACCGCAATGGTGTGCAGTAAGGACGGGCAGCTCGGTCAATTTCG
CTTCTGCCCGATTCGATTGCAGCAACGGGTCCCATTCCCTGAAGACATGTCCTTTGTCGTCATCGTTTCCGGGGTCGCGG
CCGAGAAGACCGGAGCTGCTCGTGATCTTTACAACGCGGCATCGTTGGCGACGCGCGAGATCATCGAACGGTGGAATTCG
ACCACAGGTCGTGAGGACGCTGTCCTCGGGGATGCCCTAGTGGCCGACCCTAATGCTGAGAAGTTGCACGAGGTGGTGAG
CGATCGCGCCGATCTCACTCGGCGCCTCGATCACTTCCTTACCGAGTCTGAAAGCATCATTCCTGAGGCGTCGAAAGCAC
TGGCGTGTGGTGACCTTGAAAGATTCGGTCGAATGGCTGACGAGTCGCAACGCGCGGCCGAGGACCTTCTTGGCAATCAA
GTGCCACAGACATCGGCTCTCGCGCGCATCGCTCGCGAACTTGGAGCGACTGGGGCCACCTCGTTCGGGGCAGGTTTCGG
TGGCTCGGTGTGGGCTCTCGTGCCTAATGCCGAGGCTCCGGAGTTCGCTAGTACGTGGCTCGGTAAGTACCGCGACGAGT
ACTCGGAGGAGGCTGGACAGGCCGTTACCGTGGTCACACGTCCGGGGCCCTCCGCCCGGCGCCTGGACTGA

Upstream 100 bases:

>100_bases
ATTTTGATGTCGTTCCGGTCGAGTCGGGAGTTCTCGACATGTCGAACCGCGGCGACATTACGTCTGTAGTGGAGGCTCTC
AGCAGCCGTGAGGTGAAACT

Downstream 100 bases:

>100_bases
TTCCGTTCGGCAGCCCGCTCATCGTATTCCTGCTATCGCGCAGGAGCGATGAGCGCAGTTGCCATGGGGCTGGGTTTTAC
GAACCATGAAGGCTTTTTCG

Product: galactokinase

Products: NA

Alternate protein names: Galactose kinase [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTRWFVPGRIEVLGKHTDYAGGSTLVAAVDRGVTISIEPGDSGITVSTDAAPGELSLAAGHDPKLPAGHWGRYAQAVVDR
LAANFGDLAPARIRLTSDLPLASGMSSSSALVSAIVLGLADFNGLPDTRTWQDNITDDADLAGYLACHENGMTFKNLVGA
AGVGTFGGSEDHTAMVCSKDGQLGQFRFCPIRLQQRVPFPEDMSFVVIVSGVAAEKTGAARDLYNAASLATREIIERWNS
TTGREDAVLGDALVADPNAEKLHEVVSDRADLTRRLDHFLTESESIIPEASKALACGDLERFGRMADESQRAAEDLLGNQ
VPQTSALARIARELGATGATSFGAGFGGSVWALVPNAEAPEFASTWLGKYRDEYSEEAGQAVTVVTRPGPSARRLD

Sequences:

>Translated_396_residues
MTRWFVPGRIEVLGKHTDYAGGSTLVAAVDRGVTISIEPGDSGITVSTDAAPGELSLAAGHDPKLPAGHWGRYAQAVVDR
LAANFGDLAPARIRLTSDLPLASGMSSSSALVSAIVLGLADFNGLPDTRTWQDNITDDADLAGYLACHENGMTFKNLVGA
AGVGTFGGSEDHTAMVCSKDGQLGQFRFCPIRLQQRVPFPEDMSFVVIVSGVAAEKTGAARDLYNAASLATREIIERWNS
TTGREDAVLGDALVADPNAEKLHEVVSDRADLTRRLDHFLTESESIIPEASKALACGDLERFGRMADESQRAAEDLLGNQ
VPQTSALARIARELGATGATSFGAGFGGSVWALVPNAEAPEFASTWLGKYRDEYSEEAGQAVTVVTRPGPSARRLD
>Mature_395_residues
TRWFVPGRIEVLGKHTDYAGGSTLVAAVDRGVTISIEPGDSGITVSTDAAPGELSLAAGHDPKLPAGHWGRYAQAVVDRL
AANFGDLAPARIRLTSDLPLASGMSSSSALVSAIVLGLADFNGLPDTRTWQDNITDDADLAGYLACHENGMTFKNLVGAA
GVGTFGGSEDHTAMVCSKDGQLGQFRFCPIRLQQRVPFPEDMSFVVIVSGVAAEKTGAARDLYNAASLATREIIERWNST
TGREDAVLGDALVADPNAEKLHEVVSDRADLTRRLDHFLTESESIIPEASKALACGDLERFGRMADESQRAAEDLLGNQV
PQTSALARIARELGATGATSFGAGFGGSVWALVPNAEAPEFASTWLGKYRDEYSEEAGQAVTVVTRPGPSARRLD

Specific function: Galactose metabolism; first step. [C]

COG id: COG0153

COG function: function code G; Galactokinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. GalK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786972, Length=385, Percent_Identity=26.2337662337662, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000705
- InterPro:   IPR022963
- InterPro:   IPR019741
- InterPro:   IPR019539
- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR006203
- InterPro:   IPR006206
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF10509 GalKase_gal_bdg; PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.6 [H]

Molecular weight: Translated: 41862; Mature: 41731

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00627 GHMP_KINASES_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRWFVPGRIEVLGKHTDYAGGSTLVAAVDRGVTISIEPGDSGITVSTDAAPGELSLAAG
CCCCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCEEEECCCCCCCEEEECC
HDPKLPAGHWGRYAQAVVDRLAANFGDLAPARIRLTSDLPLASGMSSSSALVSAIVLGLA
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
DFNGLPDTRTWQDNITDDADLAGYLACHENGMTFKNLVGAAGVGTFGGSEDHTAMVCSKD
HCCCCCCCCCCCCCCCCCHHHHEEEEECCCCCCHHHHHHHCCCCCCCCCCCCEEEEECCC
GQLGQFRFCPIRLQQRVPFPEDMSFVVIVSGVAAEKTGAARDLYNAASLATREIIERWNS
CCCCCEEECHHHHHCCCCCCCCCEEEEEEECCHHCCCCCHHHHHHHHHHHHHHHHHHHCC
TTGREDAVLGDALVADPNAEKLHEVVSDRADLTRRLDHFLTESESIIPEASKALACGDLE
CCCCCCHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
RFGRMADESQRAAEDLLGNQVPQTSALARIARELGATGATSFGAGFGGSVWALVPNAEAP
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCC
EFASTWLGKYRDEYSEEAGQAVTVVTRPGPSARRLD
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TRWFVPGRIEVLGKHTDYAGGSTLVAAVDRGVTISIEPGDSGITVSTDAAPGELSLAAG
CCCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCCEEEECCCCCCCEEEECC
HDPKLPAGHWGRYAQAVVDRLAANFGDLAPARIRLTSDLPLASGMSSSSALVSAIVLGLA
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
DFNGLPDTRTWQDNITDDADLAGYLACHENGMTFKNLVGAAGVGTFGGSEDHTAMVCSKD
HCCCCCCCCCCCCCCCCCHHHHEEEEECCCCCCHHHHHHHCCCCCCCCCCCCEEEEECCC
GQLGQFRFCPIRLQQRVPFPEDMSFVVIVSGVAAEKTGAARDLYNAASLATREIIERWNS
CCCCCEEECHHHHHCCCCCCCCCEEEEEEECCHHCCCCCHHHHHHHHHHHHHHHHHHHCC
TTGREDAVLGDALVADPNAEKLHEVVSDRADLTRRLDHFLTESESIIPEASKALACGDLE
CCCCCCHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
RFGRMADESQRAAEDLLGNQVPQTSALARIARELGATGATSFGAGFGGSVWALVPNAEAP
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCC
EFASTWLGKYRDEYSEEAGQAVTVVTRPGPSARRLD
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA