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The map label for this gene is glmM [H]

Identifier: 50843723

GI number: 50843723

Start: 2481125

End: 2482549

Strand: Reverse

Name: glmM [H]

Synonym: PPA2286

Alternate gene names: 50843723

Gene position: 2482549-2481125 (Counterclockwise)

Preceding gene: 50843724

Following gene: 50843712

Centisome position: 96.96

GC content: 58.67

Gene sequence:

>1425_bases
ATGGCGGACGAAATTGAATTTGGCACCGGCGGCTGGCGAGCCATCATCGCGGACACGTTTACTCGCTTAAATGTTGAGCG
GGTCGCTCAGGCGCTTGCCGACCGTATACACGACGAAAATCAGGAACATCGCCCTGTCGTCATCGGATACGACCAGCGCT
TCCTTTCCCCGGAATTCGCTTGGTGGGCAGCGGAGGTACTCGCCGGTAACGACATCGTCGTGAGAATCATCGACCGGCCT
GCTCCGACCCCGATGATCATGTGGACCGTTCGGGACCTCGGCTGTGCCTACGGTATGGCGGTGACCGCCTCCCACAACCC
TGCCACTTATAACGGTCTCAAGGTGTTCACGGAGGGTGGCCGTGATGCCAAGGTCGAGATCACTGAACCCATTCAGCACC
GCGCCAATTCCATCAGCCCAAAGGACATTAGGCGCGTGCACCGCACTGATGCCCTTCGTGACGGTGTAATTGAGGTGCAG
ACATCAATGAACTGGTACATCGACGCGATCCTTGATCATGTCGATCTGGAGGCCATCCGCCACGCCCACCTCAAGGTCGT
CCTCGACCCCATGTTTGGCGTTTCCCGCACCTGCCTCCAGACCATCCTTATGACGGCCCGTTGCGACGTCGATACCATTC
ACGAGCGTCGCGACACCCTCTTTGGTGGGCGCCTTCCTTCTCCGAATTCGCGAACCCTCCAGACTCTGGCCCAGGAGGTT
GTCGAGCGTGGAGCCGATATCGGCATTGCCACTGATGGTGACGCAGACCGCCTCGGTATCATTGATGACCAGGGGCATTT
CTTGCATCCCAACCAGATCCTCGTATTGCTGTACACCTACCTTCTGGAGGACAAGGGATGGCAGGGGCCCTGCGTGCGTA
ACCTCGCGACGACCCACCTGCTTGACCGTGTCGCCGAGGCCCACGGGCAGACCTGTTACGAGGTACCGGTCGGATTTAAG
TGGGTGTCGTCCAAGATGGCCGAGACCAACGCCGTCATCGGTGGTGAGTCCTCCGGTGGTTTGACCGTCCAGGGGCATAT
TGCAGGCAAGGACGGTGTCTATGCTGGCACCCTGCTGGTGGAAATGATCGCCAAGCGGGGTAAGAAGCTTTCGCAGATCT
ACGCCGACATCGAGGAGCGTTACGGTCGGCTAGAGATGGTGGAGGACGACTTCTCCTTCGCCCCTGAGGACAAGGAGTAC
CTCAAGAGGCGTATCTACCAGGACAAGGATCTGCCCGACTTCGGCCTAGAGGTCGATCACATCAGCGACATGGACGGGGT
GAAGGTCTATTTCGCCAACGGTGGGTGGATCATTGTTCGGTTTTCTGGCACCGAGCCTCTCCTGCGGGTCTTTTGCGAGA
TGCCTGTCGCGCAGATGGCTCGCGAATGCATCGACAAGGTCGTGAAGCACTACCACTTCGAGTGA

Upstream 100 bases:

>100_bases
GCTCATCGTATTCCTGCTATCGCGCAGGAGCGATGAGCGCAGTTGCCATGGGGCTGGGTTTTACGAACCATGAAGGCTTT
TTCGACCTAACCTGTGAGCC

Downstream 100 bases:

>100_bases
GTAACCAGCGCTGCTCTCCTCACACGTCCTGTCCGGTTCGGGAGAGCAGCAACCCGGTGACGATTTCTCCCGATCGGAGC
ATGGTCCGGGCCCTCACGTG

Product: phosphoglucomutase/phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MADEIEFGTGGWRAIIADTFTRLNVERVAQALADRIHDENQEHRPVVIGYDQRFLSPEFAWWAAEVLAGNDIVVRIIDRP
APTPMIMWTVRDLGCAYGMAVTASHNPATYNGLKVFTEGGRDAKVEITEPIQHRANSISPKDIRRVHRTDALRDGVIEVQ
TSMNWYIDAILDHVDLEAIRHAHLKVVLDPMFGVSRTCLQTILMTARCDVDTIHERRDTLFGGRLPSPNSRTLQTLAQEV
VERGADIGIATDGDADRLGIIDDQGHFLHPNQILVLLYTYLLEDKGWQGPCVRNLATTHLLDRVAEAHGQTCYEVPVGFK
WVSSKMAETNAVIGGESSGGLTVQGHIAGKDGVYAGTLLVEMIAKRGKKLSQIYADIEERYGRLEMVEDDFSFAPEDKEY
LKRRIYQDKDLPDFGLEVDHISDMDGVKVYFANGGWIIVRFSGTEPLLRVFCEMPVAQMARECIDKVVKHYHFE

Sequences:

>Translated_474_residues
MADEIEFGTGGWRAIIADTFTRLNVERVAQALADRIHDENQEHRPVVIGYDQRFLSPEFAWWAAEVLAGNDIVVRIIDRP
APTPMIMWTVRDLGCAYGMAVTASHNPATYNGLKVFTEGGRDAKVEITEPIQHRANSISPKDIRRVHRTDALRDGVIEVQ
TSMNWYIDAILDHVDLEAIRHAHLKVVLDPMFGVSRTCLQTILMTARCDVDTIHERRDTLFGGRLPSPNSRTLQTLAQEV
VERGADIGIATDGDADRLGIIDDQGHFLHPNQILVLLYTYLLEDKGWQGPCVRNLATTHLLDRVAEAHGQTCYEVPVGFK
WVSSKMAETNAVIGGESSGGLTVQGHIAGKDGVYAGTLLVEMIAKRGKKLSQIYADIEERYGRLEMVEDDFSFAPEDKEY
LKRRIYQDKDLPDFGLEVDHISDMDGVKVYFANGGWIIVRFSGTEPLLRVFCEMPVAQMARECIDKVVKHYHFE
>Mature_473_residues
ADEIEFGTGGWRAIIADTFTRLNVERVAQALADRIHDENQEHRPVVIGYDQRFLSPEFAWWAAEVLAGNDIVVRIIDRPA
PTPMIMWTVRDLGCAYGMAVTASHNPATYNGLKVFTEGGRDAKVEITEPIQHRANSISPKDIRRVHRTDALRDGVIEVQT
SMNWYIDAILDHVDLEAIRHAHLKVVLDPMFGVSRTCLQTILMTARCDVDTIHERRDTLFGGRLPSPNSRTLQTLAQEVV
ERGADIGIATDGDADRLGIIDDQGHFLHPNQILVLLYTYLLEDKGWQGPCVRNLATTHLLDRVAEAHGQTCYEVPVGFKW
VSSKMAETNAVIGGESSGGLTVQGHIAGKDGVYAGTLLVEMIAKRGKKLSQIYADIEERYGRLEMVEDDFSFAPEDKEYL
KRRIYQDKDLPDFGLEVDHISDMDGVKVYFANGGWIIVRFSGTEPLLRVFCEMPVAQMARECIDKVVKHYHFE

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=498, Percent_Identity=25.5020080321285, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI290463102, Length=480, Percent_Identity=25, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI133922562, Length=408, Percent_Identity=25, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI290463104, Length=298, Percent_Identity=28.5234899328859, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1786904, Length=499, Percent_Identity=26.0521042084168, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788361, Length=438, Percent_Identity=24.4292237442922, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1789566, Length=386, Percent_Identity=24.6113989637306, Blast_Score=88, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17535441, Length=420, Percent_Identity=27.1428571428571, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI71993870, Length=526, Percent_Identity=23.9543726235741, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71993878, Length=299, Percent_Identity=26.0869565217391, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323752, Length=485, Percent_Identity=24.7422680412371, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322722, Length=485, Percent_Identity=23.9175257731959, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323934, Length=412, Percent_Identity=24.5145631067961, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17864244, Length=493, Percent_Identity=25.9634888438134, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI20129809, Length=525, Percent_Identity=25.9047619047619, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24651977, Length=422, Percent_Identity=27.4881516587678, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24653722, Length=483, Percent_Identity=23.3954451345756, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 53246; Mature: 53115

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEIEFGTGGWRAIIADTFTRLNVERVAQALADRIHDENQEHRPVVIGYDQRFLSPEFA
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEECCHHHCCCHHH
WWAAEVLAGNDIVVRIIDRPAPTPMIMWTVRDLGCAYGMAVTASHNPATYNGLKVFTEGG
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEHHHHHHHCEEEEECCCCCCCCCEEEEECCC
RDAKVEITEPIQHRANSISPKDIRRVHRTDALRDGVIEVQTSMNWYIDAILDHVDLEAIR
CCEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHH
HAHLKVVLDPMFGVSRTCLQTILMTARCDVDTIHERRDTLFGGRLPSPNSRTLQTLAQEV
HHHHEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VERGADIGIATDGDADRLGIIDDQGHFLHPNQILVLLYTYLLEDKGWQGPCVRNLATTHL
HHCCCCEEEECCCCCCCEEEEECCCCEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LDRVAEAHGQTCYEVPVGFKWVSSKMAETNAVIGGESSGGLTVQGHIAGKDGVYAGTLLV
HHHHHHHCCCEEEECCCCHHHHHHHHHHCCEEECCCCCCCEEEEEEECCCCCCHHHHHHH
EMIAKRGKKLSQIYADIEERYGRLEMVEDDFSFAPEDKEYLKRRIYQDKDLPDFGLEVDH
HHHHHHCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCEECC
ISDMDGVKVYFANGGWIIVRFSGTEPLLRVFCEMPVAQMARECIDKVVKHYHFE
CCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADEIEFGTGGWRAIIADTFTRLNVERVAQALADRIHDENQEHRPVVIGYDQRFLSPEFA
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEECCHHHCCCHHH
WWAAEVLAGNDIVVRIIDRPAPTPMIMWTVRDLGCAYGMAVTASHNPATYNGLKVFTEGG
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEHHHHHHHCEEEEECCCCCCCCCEEEEECCC
RDAKVEITEPIQHRANSISPKDIRRVHRTDALRDGVIEVQTSMNWYIDAILDHVDLEAIR
CCEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHH
HAHLKVVLDPMFGVSRTCLQTILMTARCDVDTIHERRDTLFGGRLPSPNSRTLQTLAQEV
HHHHEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VERGADIGIATDGDADRLGIIDDQGHFLHPNQILVLLYTYLLEDKGWQGPCVRNLATTHL
HHCCCCEEEECCCCCCCEEEEECCCCEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LDRVAEAHGQTCYEVPVGFKWVSSKMAETNAVIGGESSGGLTVQGHIAGKDGVYAGTLLV
HHHHHHHCCCEEEECCCCHHHHHHHHHHCCEEECCCCCCCEEEEEEECCCCCCHHHHHHH
EMIAKRGKKLSQIYADIEERYGRLEMVEDDFSFAPEDKEYLKRRIYQDKDLPDFGLEVDH
HHHHHHCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCEECC
ISDMDGVKVYFANGGWIIVRFSGTEPLLRVFCEMPVAQMARECIDKVVKHYHFE
CCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]