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The map label for this gene is 50843681

Identifier: 50843681

GI number: 50843681

Start: 2430319

End: 2430894

Strand: Direct

Name: 50843681

Synonym: PPA2247

Alternate gene names: NA

Gene position: 2430319-2430894 (Clockwise)

Preceding gene: 50843680

Following gene: 50843686

Centisome position: 94.92

GC content: 63.54

Gene sequence:

>576_bases
ATGATCGACCTCTCGGCTCCCGCTATCGAGGTCGCCCCGCTCCTACTCGGGGCAACGATCTGGCGCGGCCCGGTGGGGAT
CCGTCTCACCGAAGTCGAGGCGTACATGGGACTCGACGACCCAGCATCCCATGCCTTTCGTGGGCCAACCCCGCGCGCCC
GCGTGATGTTCGGGCCGCCTTCTCACATATACGTGTACTTGTCTTACGGCATGCATCGCTGCGTGAACCTCGTGTGTTCA
CCAGACGGGGAGGCATCTGCCGTGCTACTGCGTGGCGGGCAAGTCATAGCAGGCCACGATGATGCTCGTCGGCGTCGCGG
GAACGTCGCCGAGAACCGCCTTGCCTGCGGACCAGGAAATATGGGGTCAGCTTTGGGTGCCAGTCTCGAAGAGTCTGGAA
ACCCGGTGAGCATCATCGGCAATGGTGCGATATCTGCCTTGGGCTGGCGCCTCGAACCCGCACCGGAGATTGCCGAATTC
CGACAGGGCCCGCGAGTAGGGATCAGCCGCAACATTGACGCCCCTTGGCGGTGGTGGATTCCCCAGGACCCCACGGTCTC
GGGCCCCCGAACATAA

Upstream 100 bases:

>100_bases
CTTCTCACGGATTGGCAAAGAAGATCGGTGCTTGGCCAGCGGTCATCACCGTGACCGCCGCTACCTGCACTGCGTGCCAC
TTCCTGTGCGACACCAAGGC

Downstream 100 bases:

>100_bases
GCCACAACGGTCGCAAGGTCAGCACCCCCTGACCTGCCGTGCCCTCCCAACCCCCCCCGGTGACAAAAAATCCCGACCCA
CAACAGGCCACATCACAGCA

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MIDLSAPAIEVAPLLLGATIWRGPVGIRLTEVEAYMGLDDPASHAFRGPTPRARVMFGPPSHIYVYLSYGMHRCVNLVCS
PDGEASAVLLRGGQVIAGHDDARRRRGNVAENRLACGPGNMGSALGASLEESGNPVSIIGNGAISALGWRLEPAPEIAEF
RQGPRVGISRNIDAPWRWWIPQDPTVSGPRT

Sequences:

>Translated_191_residues
MIDLSAPAIEVAPLLLGATIWRGPVGIRLTEVEAYMGLDDPASHAFRGPTPRARVMFGPPSHIYVYLSYGMHRCVNLVCS
PDGEASAVLLRGGQVIAGHDDARRRRGNVAENRLACGPGNMGSALGASLEESGNPVSIIGNGAISALGWRLEPAPEIAEF
RQGPRVGISRNIDAPWRWWIPQDPTVSGPRT
>Mature_191_residues
MIDLSAPAIEVAPLLLGATIWRGPVGIRLTEVEAYMGLDDPASHAFRGPTPRARVMFGPPSHIYVYLSYGMHRCVNLVCS
PDGEASAVLLRGGQVIAGHDDARRRRGNVAENRLACGPGNMGSALGASLEESGNPVSIIGNGAISALGWRLEPAPEIAEF
RQGPRVGISRNIDAPWRWWIPQDPTVSGPRT

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=138, Percent_Identity=34.0579710144928, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI62632771, Length=138, Percent_Identity=34.0579710144928, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI62632765, Length=138, Percent_Identity=34.0579710144928, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_PROAC (Q6A5L3)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056908.1
- HSSP:   P29372
- ProteinModelPortal:   Q6A5L3
- GeneID:   2931754
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA2247
- HOGENOM:   HBG664239
- OMA:   PEPENIL
- ProtClustDB:   PRK00802
- BioCyc:   PACN267747:PPA2247-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 20412; Mature: 20412

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLSAPAIEVAPLLLGATIWRGPVGIRLTEVEAYMGLDDPASHAFRGPTPRARVMFGPP
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHEECCCCCCHHHCCCCCCCCCEEEECCC
SHIYVYLSYGMHRCVNLVCSPDGEASAVLLRGGQVIAGHDDARRRRGNVAENRLACGPGN
CEEEEEEEHHHHHHEEEEECCCCCCEEEEEECCEEEECCCHHHHHCCCCCCCCEECCCCC
MGSALGASLEESGNPVSIIGNGAISALGWRLEPAPEIAEFRQGPRVGISRNIDAPWRWWI
CCHHHCCCHHHCCCEEEEEECCCEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEC
PQDPTVSGPRT
CCCCCCCCCCC
>Mature Secondary Structure
MIDLSAPAIEVAPLLLGATIWRGPVGIRLTEVEAYMGLDDPASHAFRGPTPRARVMFGPP
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHEECCCCCCHHHCCCCCCCCCEEEECCC
SHIYVYLSYGMHRCVNLVCSPDGEASAVLLRGGQVIAGHDDARRRRGNVAENRLACGPGN
CEEEEEEEHHHHHHEEEEECCCCCCEEEEEECCEEEECCCHHHHHCCCCCCCCEECCCCC
MGSALGASLEESGNPVSIIGNGAISALGWRLEPAPEIAEFRQGPRVGISRNIDAPWRWWI
CCHHHCCCHHHCCCEEEEEECCCEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEC
PQDPTVSGPRT
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA