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The map label for this gene is ygcW [C]

Identifier: 50843671

GI number: 50843671

Start: 2420039

End: 2420848

Strand: Direct

Name: ygcW [C]

Synonym: PPA2236

Alternate gene names: 50843671

Gene position: 2420039-2420848 (Clockwise)

Preceding gene: 50843658

Following gene: 50843672

Centisome position: 94.52

GC content: 61.6

Gene sequence:

>810_bases
ATGGCAACGAGCATGGTCACGGGCGGAACATCAGGCATCGGCCGCGAATTCGTCACCCAACTGGCTGCCCGCGGCGACGA
CATCGTCATCGTCGCCCGCGATACCGAGCGCATGGCCGCGATCAAGGCGGACGTTGAGGCCCGTTACGGGGTTTCCGTCG
AGACCATTGCAGCAGACCTATCGCGCCGCGAGGACGTCGACCAGATCACCACTCGGGTGGAGGACCCCAACCACCCCGTC
GATCTATTGGTCAACAACGCCGGGTTCGCAGTGCACGCCAAGATCCTCGACCCTGAGGCCCTTGAACTACACGACCGCGC
CGTCGAGGTCATGATGCGGGCAGTCCTGGTGCTCTCAGCAGCAGCAGGACGGGCAATGAAGGCCCGCGGACATGGGGCCA
TCCTCAACCTTTCCTCGTCAAGCGCTTGGATCAACACTGGCAATTACTCCGCCATCAAAGCGTGGGTACTCACCTTCACC
GAGGGCCTGTCCAACGAGCTGGCCGGCACCGGCGTCAAGGCCATGGCGCTGTGCCCGGGATGGGTACACACCGAATTCCA
CTCACGCGCCAACGTCACCGCCAACCATCTGCCGGACTTTTTCTGGATCGACGCCGAAGTCCTGGTACGCGAGGCTCTCA
ACGACCTTGACCATGACAAGGTAGTATCCATTCCTACCCCGCTCTGGAAGTTCTTCATCGCAGTGGCCACACATACCCCA
CGTTCCGCTATGAGATTCCTGTCACGAACTCTGTCCTCGTCTCGAGACAAGGACGACCACCCTCGACACACTCCGGGAGG
CGAGGCCTGA

Upstream 100 bases:

>100_bases
GCCATGAGGTAGCGACTGTCCGACGTTCGTTATGACGGAACGCTGACGAAAGTCGCTGCGATGATGGTGACCATCCCCGC
AGTGCCGTAGATTGGACGGT

Downstream 100 bases:

>100_bases
GATGGCCAGCGTCAAACCCACTAAGGACCGGGGCCGGTACACCAATGATCTGTCCGCCGCGACGCGGCAGGCAGCGAACA
TGCTTCTGCTGCGTCCTTTG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MATSMVTGGTSGIGREFVTQLAARGDDIVIVARDTERMAAIKADVEARYGVSVETIAADLSRREDVDQITTRVEDPNHPV
DLLVNNAGFAVHAKILDPEALELHDRAVEVMMRAVLVLSAAAGRAMKARGHGAILNLSSSSAWINTGNYSAIKAWVLTFT
EGLSNELAGTGVKAMALCPGWVHTEFHSRANVTANHLPDFFWIDAEVLVREALNDLDHDKVVSIPTPLWKFFIAVATHTP
RSAMRFLSRTLSSSRDKDDHPRHTPGGEA

Sequences:

>Translated_269_residues
MATSMVTGGTSGIGREFVTQLAARGDDIVIVARDTERMAAIKADVEARYGVSVETIAADLSRREDVDQITTRVEDPNHPV
DLLVNNAGFAVHAKILDPEALELHDRAVEVMMRAVLVLSAAAGRAMKARGHGAILNLSSSSAWINTGNYSAIKAWVLTFT
EGLSNELAGTGVKAMALCPGWVHTEFHSRANVTANHLPDFFWIDAEVLVREALNDLDHDKVVSIPTPLWKFFIAVATHTP
RSAMRFLSRTLSSSRDKDDHPRHTPGGEA
>Mature_268_residues
ATSMVTGGTSGIGREFVTQLAARGDDIVIVARDTERMAAIKADVEARYGVSVETIAADLSRREDVDQITTRVEDPNHPVD
LLVNNAGFAVHAKILDPEALELHDRAVEVMMRAVLVLSAAAGRAMKARGHGAILNLSSSSAWINTGNYSAIKAWVLTFTE
GLSNELAGTGVKAMALCPGWVHTEFHSRANVTANHLPDFFWIDAEVLVREALNDLDHDKVVSIPTPLWKFFIAVATHTPR
SAMRFLSRTLSSSRDKDDHPRHTPGGEA

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=189, Percent_Identity=27.5132275132275, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4557649, Length=222, Percent_Identity=28.8288288288288, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI226371731, Length=193, Percent_Identity=29.0155440414508, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=207, Percent_Identity=32.3671497584541, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=30.5699481865285, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI210032110, Length=255, Percent_Identity=25.0980392156863, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082160, Length=224, Percent_Identity=28.125, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=27.9569892473118, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367175, Length=195, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=26.8817204301075, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790717, Length=187, Percent_Identity=27.807486631016, Blast_Score=67, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17560176, Length=223, Percent_Identity=25.5605381165919, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17559552, Length=228, Percent_Identity=25.8771929824561, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=193, Percent_Identity=27.4611398963731, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=197, Percent_Identity=27.4111675126904, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=199, Percent_Identity=30.1507537688442, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=194, Percent_Identity=26.2886597938144, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212646214, Length=228, Percent_Identity=25.8771929824561, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=187, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17557668, Length=228, Percent_Identity=24.5614035087719, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=193, Percent_Identity=26.9430051813472, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=193, Percent_Identity=26.4248704663212, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=234, Percent_Identity=27.3504273504274, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=189, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=223, Percent_Identity=24.6636771300448, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319635, Length=177, Percent_Identity=25.9887005649718, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28574402, Length=190, Percent_Identity=33.1578947368421, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=33.1578947368421, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI161076933, Length=200, Percent_Identity=32.5, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24584748, Length=200, Percent_Identity=32.5, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24584752, Length=229, Percent_Identity=28.3842794759825, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=200, Percent_Identity=30, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640442, Length=224, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=200, Percent_Identity=25.5, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=26.2886597938144, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29202; Mature: 29071

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSMVTGGTSGIGREFVTQLAARGDDIVIVARDTERMAAIKADVEARYGVSVETIAADL
CCCCEECCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCHHHCCCCHHHHHHHH
SRREDVDQITTRVEDPNHPVDLLVNNAGFAVHAKILDPEALELHDRAVEVMMRAVLVLSA
HHHCCHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AAGRAMKARGHGAILNLSSSSAWINTGNYSAIKAWVLTFTEGLSNELAGTGVKAMALCPG
HCCCCEECCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
WVHTEFHSRANVTANHLPDFFWIDAEVLVREALNDLDHDKVVSIPTPLWKFFIAVATHTP
HHHHHHHCCCCCCHHHCCCEEEECHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHCCCC
RSAMRFLSRTLSSSRDKDDHPRHTPGGEA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATSMVTGGTSGIGREFVTQLAARGDDIVIVARDTERMAAIKADVEARYGVSVETIAADL
CCCEECCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCHHHCCCCHHHHHHHH
SRREDVDQITTRVEDPNHPVDLLVNNAGFAVHAKILDPEALELHDRAVEVMMRAVLVLSA
HHHCCHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
AAGRAMKARGHGAILNLSSSSAWINTGNYSAIKAWVLTFTEGLSNELAGTGVKAMALCPG
HCCCCEECCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
WVHTEFHSRANVTANHLPDFFWIDAEVLVREALNDLDHDKVVSIPTPLWKFFIAVATHTP
HHHHHHHCCCCCCHHHCCCEEEECHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHCCCC
RSAMRFLSRTLSSSRDKDDHPRHTPGGEA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA