Click here to switch to the map view.

The map label for this gene is uppP

Identifier: 50843659

GI number: 50843659

Start: 2409007

End: 2409861

Strand: Reverse

Name: uppP

Synonym: PPA2224

Alternate gene names: 50843659

Gene position: 2409861-2409007 (Counterclockwise)

Preceding gene: 50843660

Following gene: 50843656

Centisome position: 94.13

GC content: 58.6

Gene sequence:

>855_bases
GTGAACTGGCTGCACGCCATCATCCTCGGCATAGTCGAGGGCATCACCGAGTTCCTGCCTGTTTCCAGCACCGGACATCT
GCGTATCGTGGAGAAGCTGCTGGGGTACGACATCCAGGGTGCCGGGATCACTGCCTTCACCGCGATCATTCAGGTTGGTG
CGATCATTGCCGCCATTCTGTATTTCTGGTCTGACATCGTGCGCATCGTCGTCGCATGGTGCAAGGGTCTGGCCCACAAA
GAAGACCGTGACGACCCGGACTACACCCTCGGCTGGGGAATCATCCTGGGCTCGATTCCGGTGGGCGTCGTAGGGCTGGT
ATTCAAGGACGCCATCGAGACCACGCTGAGCTCTCTGTGGGTGGTTGCCATTGCTCTTATCCTCTGGAGCGGTGTGATGT
GGTTGGGCGATCGTCAGTTGGGCCTCAACAGGGGCATGAAAGAGATTGGCATCGTCGACGCCATTGTTATCGGGTGTTTC
CAGGCTCTGGCCCCGCTCTTTCCTGGTATCTCCCGTTCGGGTGCGACGATTTCTGCCGGTTTGTTCCGCAAGTTCGACCG
TGCCACAGCCACCCGACTCTCATTCTTCATGGGCATTCCGGCGCTGGTTGCGGCCGGGATTTACGAGTCGGTCTCCGCCG
CTAGTGACATTTCCATCGCTCAAGGTGGTGCTGTCGCGATCGGTTGGGGGCCGACGATTCTGGCGACCGTGGTCTCCCTC
ATCGTGGCCTACGTTTCCATCGCGTGGCTGCTGAAGTTCGTCTCGTCGAATAAGTTCACTGGGTTCATGTGGTACCGCGT
CGTCGTGGGGCTCATCATAATTGGTCTGATTCTGTCCAACGTCGTCACCGCCTGA

Upstream 100 bases:

>100_bases
GTGACAGGGATGCGGACGTTGTCGCTCTCAGCGTCTAGTGTGTGAGCCCGGGTGCACTGACCCCCATCCGCACGGCCCCC
CAATCGAGAGGTTTTCATCC

Downstream 100 bases:

>100_bases
CCTGAAATGCGACAAGCTTGGTGTGAGCAGGGAATGCCCCAGGTGGACCGTTTTAGTCTCCCGACTCGGCGTCCATGGAG
CGGTTGAAGTCCTGCTTTAT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MNWLHAIILGIVEGITEFLPVSSTGHLRIVEKLLGYDIQGAGITAFTAIIQVGAIIAAILYFWSDIVRIVVAWCKGLAHK
EDRDDPDYTLGWGIILGSIPVGVVGLVFKDAIETTLSSLWVVAIALILWSGVMWLGDRQLGLNRGMKEIGIVDAIVIGCF
QALAPLFPGISRSGATISAGLFRKFDRATATRLSFFMGIPALVAAGIYESVSAASDISIAQGGAVAIGWGPTILATVVSL
IVAYVSIAWLLKFVSSNKFTGFMWYRVVVGLIIIGLILSNVVTA

Sequences:

>Translated_284_residues
MNWLHAIILGIVEGITEFLPVSSTGHLRIVEKLLGYDIQGAGITAFTAIIQVGAIIAAILYFWSDIVRIVVAWCKGLAHK
EDRDDPDYTLGWGIILGSIPVGVVGLVFKDAIETTLSSLWVVAIALILWSGVMWLGDRQLGLNRGMKEIGIVDAIVIGCF
QALAPLFPGISRSGATISAGLFRKFDRATATRLSFFMGIPALVAAGIYESVSAASDISIAQGGAVAIGWGPTILATVVSL
IVAYVSIAWLLKFVSSNKFTGFMWYRVVVGLIIIGLILSNVVTA
>Mature_284_residues
MNWLHAIILGIVEGITEFLPVSSTGHLRIVEKLLGYDIQGAGITAFTAIIQVGAIIAAILYFWSDIVRIVVAWCKGLAHK
EDRDDPDYTLGWGIILGSIPVGVVGLVFKDAIETTLSSLWVVAIALILWSGVMWLGDRQLGLNRGMKEIGIVDAIVIGCF
QALAPLFPGISRSGATISAGLFRKFDRATATRLSFFMGIPALVAAGIYESVSAASDISIAQGGAVAIGWGPTILATVVSL
IVAYVSIAWLLKFVSSNKFTGFMWYRVVVGLIIIGLILSNVVTA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=274, Percent_Identity=34.6715328467153, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_PROAC (Q6A5N5)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056886.1
- GeneID:   2931906
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA2224
- NMPDR:   fig|267747.1.peg.2163
- HOGENOM:   HBG391969
- OMA:   DISIAQG
- ProtClustDB:   PRK00281
- BioCyc:   PACN267747:PPA2224-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30279; Mature: 30279

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14efb508)-; HASH(0x14f165f0)-; HASH(0x14159cbc)-; HASH(0x1376aa14)-; HASH(0x14b5eb90)-; HASH(0x14a6f850)-; HASH(0x15236504)-; HASH(0x14eb5760)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWLHAIILGIVEGITEFLPVSSTGHLRIVEKLLGYDIQGAGITAFTAIIQVGAIIAAIL
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YFWSDIVRIVVAWCKGLAHKEDRDDPDYTLGWGIILGSIPVGVVGLVFKDAIETTLSSLW
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAIALILWSGVMWLGDRQLGLNRGMKEIGIVDAIVIGCFQALAPLFPGISRSGATISAG
HHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LFRKFDRATATRLSFFMGIPALVAAGIYESVSAASDISIAQGGAVAIGWGPTILATVVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHH
IVAYVSIAWLLKFVSSNKFTGFMWYRVVVGLIIIGLILSNVVTA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNWLHAIILGIVEGITEFLPVSSTGHLRIVEKLLGYDIQGAGITAFTAIIQVGAIIAAIL
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YFWSDIVRIVVAWCKGLAHKEDRDDPDYTLGWGIILGSIPVGVVGLVFKDAIETTLSSLW
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAIALILWSGVMWLGDRQLGLNRGMKEIGIVDAIVIGCFQALAPLFPGISRSGATISAG
HHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LFRKFDRATATRLSFFMGIPALVAAGIYESVSAASDISIAQGGAVAIGWGPTILATVVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHH
IVAYVSIAWLLKFVSSNKFTGFMWYRVVVGLIIIGLILSNVVTA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA