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The map label for this gene is kup

Identifier: 50843624

GI number: 50843624

Start: 2367841

End: 2369796

Strand: Direct

Name: kup

Synonym: PPA2187

Alternate gene names: 50843624

Gene position: 2367841-2369796 (Clockwise)

Preceding gene: 50843622

Following gene: 50843626

Centisome position: 92.48

GC content: 59.05

Gene sequence:

>1956_bases
GTGATTCGCAGCCATGAACGGCAGGCGGTGGCCAAAGCCACCCAGCCGATCGTTGATCGTGAACCGATCCGATCCATGAA
ACCTGGACTAGCCCTAGCCGCATTAGGAATCGTCTTCGGCGATATCGGCACCTCAGTCCTTTACTCTCTCCAAACGGTGT
TCTCAATGGAGAACCATGCCGTGCGCCCAACCCACGGTGACGTCATGGGGATCATCTCGATGATCTTCTGGTCGATCCTG
CTCGTGGTGTGTGTCAAATACGTCATATTCGTTATGCGCGCTGACAACGACGGCGAAGGGGGCATCCTCGCCCTGATGGC
CTTGGTACGTCGACTCATGGCTAGCCACAAGGGCACTGGCATGACGGCGCTCCTACTCGGCATCGTTGGCGCCGGCCTAT
TTTACGGAGATTCCTTTATCACCCCAGCGATTTCCGTGATGAGCGCTGTGGAAGGCCTCACGGTAGCCAACCCGGATGCA
GAAAAGATCGTCCTGCCAGCCTCGGTCGTCATCCTTACCCTCTTATTCATCGTGCAGAGACGGGGAACGGAGGTCATTGG
CAAGGCCTTCGGACCGGTAATGGCGACCTGGTTCCTCACCCTGGCGGCCTTGGGCATTCCGTGGATCATCCACCACCCGG
TCATCATTACGGCCTTGTCTCCGCACTGGGCAATCCTGTTTTCCATCGAGCGTCCAGCGATGGCTTTCATTGCGATGGGC
GCGGTCGTCTTGACGATTACCGGTGCCGAGGCGCTATACGCCGACATGGGCCACGTCGGGGCTCCATCGATCCGACTTGC
CTGGTTCGGCCTTGTGCTCCCCTGTTTGCTCATCAACTACCTGGGCCAGGGGGCCATGATCCTGTCGCACCCCGACTGGA
TCGATAACCCGTTCTTTAGGATGGCTCCCGACTGGGCGACTATTCCGCTTGTCACCATCGCCACAATGGCCACCGTCATC
GCTTCTCAGGCAGTCATCTCGGGGGCGTTCTCGATGAGTTCAGAGGCCGCCCGCCTGGGGTTACTGCCGCGCCTCGGCGT
GCGTCATACCTCGAAGTCCGAGGGCGGCCAAATCTATATCCCAGAGGTCAACTGGACCCTCTTTATCGGCGTGCTAGCCC
TCATCCTCATCTTCCAGACCTCGTCGAAACTAGCCACGGCTTATGGTTTGGCCGTGACCGGCACCTTCCTCCTGACGACG
AGCCTGTTTCTGGTGCTGGCTCACCGGGCATGGCATTGGCCGATGTGGGCTCTCATCTTTTTTGGTGTCATTGTCGGCGG
CGTCGAGTTGTCGATTTTCTCCGCCAATCTGTTGAAGATCGCCTCTGGCGGCTGGATCCCGCTGTTGTTCGCAACCATCG
TCGTCATCATCATGACGACGTGGCGACGCGGCACCGCCTACATCGCCAAGCAGCGACAAGATGATGAGGGGCCGCTGGAC
GACTTCCTCAACTGGATGCACGAAACCAAGCCAACCCGCGTCCCTGGCCTGGCCGTTTACCCGCATCCTGGGCGGGCAAC
AACCCCGTTGGCCCTGCTTAATAACCTCAGGTTTAACCATGTGCTGCATGAGCACAACATCATCATCTCGATAGTGGTGG
AGAACGTGCCGCACGTGCGGCACGTCAACCGTATTGAGAAAGTAGACCTCGGCAGACCCACCGACGGCATCACTTATATC
GCGTGTCACGTCGGGTTCACCGATTCCCAGGACGTCCCCAAGGCGCTAGCTCTGGCGGCGGCCAAGTGTCCTTGGCTCAA
GGATCATCTCGACGAGGCGATCTACTACCTCTCCCTAGTAGACGTGAAGCGGGACGAACCACAACAGGGTGCGCACATGG
CCGGCTGGCGCAAGATGCTTTACATCACTATGTCGCGCAACCAGGCCGATCGCACTCGGGTGTTCCGGATACCGCGCACT
CGCGCGGTGGTTATGGGTGAGGCCGTCGCCTTGTGA

Upstream 100 bases:

>100_bases
AGCATCACAGAGGACCTCACGATCACTTTTCCCGCCCATGCGCTACGTCTGATTCGCCGATCAATTTGCAGGTGAGGCGA
TGAGGTCCATACTTTCTTGA

Downstream 100 bases:

>100_bases
CGGTCTGTCGCTGATACTCACAACTGATTCCCGAGGCCTACTGAGCCTCGGGAATCACCTTTTCTCAGGGTCTATAAGTT
CCTGGAATCGCGCCGCGAAA

Product: K+ potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MIRSHERQAVAKATQPIVDREPIRSMKPGLALAALGIVFGDIGTSVLYSLQTVFSMENHAVRPTHGDVMGIISMIFWSIL
LVVCVKYVIFVMRADNDGEGGILALMALVRRLMASHKGTGMTALLLGIVGAGLFYGDSFITPAISVMSAVEGLTVANPDA
EKIVLPASVVILTLLFIVQRRGTEVIGKAFGPVMATWFLTLAALGIPWIIHHPVIITALSPHWAILFSIERPAMAFIAMG
AVVLTITGAEALYADMGHVGAPSIRLAWFGLVLPCLLINYLGQGAMILSHPDWIDNPFFRMAPDWATIPLVTIATMATVI
ASQAVISGAFSMSSEAARLGLLPRLGVRHTSKSEGGQIYIPEVNWTLFIGVLALILIFQTSSKLATAYGLAVTGTFLLTT
SLFLVLAHRAWHWPMWALIFFGVIVGGVELSIFSANLLKIASGGWIPLLFATIVVIIMTTWRRGTAYIAKQRQDDEGPLD
DFLNWMHETKPTRVPGLAVYPHPGRATTPLALLNNLRFNHVLHEHNIIISIVVENVPHVRHVNRIEKVDLGRPTDGITYI
ACHVGFTDSQDVPKALALAAAKCPWLKDHLDEAIYYLSLVDVKRDEPQQGAHMAGWRKMLYITMSRNQADRTRVFRIPRT
RAVVMGEAVAL

Sequences:

>Translated_651_residues
MIRSHERQAVAKATQPIVDREPIRSMKPGLALAALGIVFGDIGTSVLYSLQTVFSMENHAVRPTHGDVMGIISMIFWSIL
LVVCVKYVIFVMRADNDGEGGILALMALVRRLMASHKGTGMTALLLGIVGAGLFYGDSFITPAISVMSAVEGLTVANPDA
EKIVLPASVVILTLLFIVQRRGTEVIGKAFGPVMATWFLTLAALGIPWIIHHPVIITALSPHWAILFSIERPAMAFIAMG
AVVLTITGAEALYADMGHVGAPSIRLAWFGLVLPCLLINYLGQGAMILSHPDWIDNPFFRMAPDWATIPLVTIATMATVI
ASQAVISGAFSMSSEAARLGLLPRLGVRHTSKSEGGQIYIPEVNWTLFIGVLALILIFQTSSKLATAYGLAVTGTFLLTT
SLFLVLAHRAWHWPMWALIFFGVIVGGVELSIFSANLLKIASGGWIPLLFATIVVIIMTTWRRGTAYIAKQRQDDEGPLD
DFLNWMHETKPTRVPGLAVYPHPGRATTPLALLNNLRFNHVLHEHNIIISIVVENVPHVRHVNRIEKVDLGRPTDGITYI
ACHVGFTDSQDVPKALALAAAKCPWLKDHLDEAIYYLSLVDVKRDEPQQGAHMAGWRKMLYITMSRNQADRTRVFRIPRT
RAVVMGEAVAL
>Mature_651_residues
MIRSHERQAVAKATQPIVDREPIRSMKPGLALAALGIVFGDIGTSVLYSLQTVFSMENHAVRPTHGDVMGIISMIFWSIL
LVVCVKYVIFVMRADNDGEGGILALMALVRRLMASHKGTGMTALLLGIVGAGLFYGDSFITPAISVMSAVEGLTVANPDA
EKIVLPASVVILTLLFIVQRRGTEVIGKAFGPVMATWFLTLAALGIPWIIHHPVIITALSPHWAILFSIERPAMAFIAMG
AVVLTITGAEALYADMGHVGAPSIRLAWFGLVLPCLLINYLGQGAMILSHPDWIDNPFFRMAPDWATIPLVTIATMATVI
ASQAVISGAFSMSSEAARLGLLPRLGVRHTSKSEGGQIYIPEVNWTLFIGVLALILIFQTSSKLATAYGLAVTGTFLLTT
SLFLVLAHRAWHWPMWALIFFGVIVGGVELSIFSANLLKIASGGWIPLLFATIVVIIMTTWRRGTAYIAKQRQDDEGPLD
DFLNWMHETKPTRVPGLAVYPHPGRATTPLALLNNLRFNHVLHEHNIIISIVVENVPHVRHVNRIEKVDLGRPTDGITYI
ACHVGFTDSQDVPKALALAAAKCPWLKDHLDEAIYYLSLVDVKRDEPQQGAHMAGWRKMLYITMSRNQADRTRVFRIPRT
RAVVMGEAVAL

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=627, Percent_Identity=43.3811802232855, Blast_Score=499, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_PROAC (Q6A5S0)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056851.1
- GeneID:   2932218
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA2187
- NMPDR:   fig|267747.1.peg.2128
- HOGENOM:   HBG351154
- OMA:   KLFATIK
- ProtClustDB:   CLSK2764408
- BioCyc:   PACN267747:PPA2187-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 71178; Mature: 71178

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14987d80)-; HASH(0x13f91eb8)-; HASH(0x14488354)-; HASH(0x146e191c)-; HASH(0x14c03cd8)-; HASH(0x14592840)-; HASH(0x14d1c1d0)-; HASH(0x14cb82bc)-; HASH(0x13965ef4)-; HASH(0x133fd768)-; HASH(0x143af2b0)-; HASH(0x14856140)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSHERQAVAKATQPIVDREPIRSMKPGLALAALGIVFGDIGTSVLYSLQTVFSMENHA
CCCCHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VRPTHGDVMGIISMIFWSILLVVCVKYVIFVMRADNDGEGGILALMALVRRLMASHKGTG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
MTALLLGIVGAGLFYGDSFITPAISVMSAVEGLTVANPDAEKIVLPASVVILTLLFIVQR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEHHHHHHHHHHHHHHH
RGTEVIGKAFGPVMATWFLTLAALGIPWIIHHPVIITALSPHWAILFSIERPAMAFIAMG
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCEEEEEEECCHHHHHHHHH
AVVLTITGAEALYADMGHVGAPSIRLAWFGLVLPCLLINYLGQGAMILSHPDWIDNPFFR
HHEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCE
MAPDWATIPLVTIATMATVIASQAVISGAFSMSSEAARLGLLPRLGVRHTSKSEGGQIYI
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCEEEE
PEVNWTLFIGVLALILIFQTSSKLATAYGLAVTGTFLLTTSLFLVLAHRAWHWPMWALIF
ECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FGVIVGGVELSIFSANLLKIASGGWIPLLFATIVVIIMTTWRRGTAYIAKQRQDDEGPLD
HHHHHCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHH
DFLNWMHETKPTRVPGLAVYPHPGRATTPLALLNNLRFNHVLHEHNIIISIVVENVPHVR
HHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHCCHHHHHHHHCCEEEEEEECCCCCHH
HVNRIEKVDLGRPTDGITYIACHVGFTDSQDVPKALALAAAKCPWLKDHLDEAIYYLSLV
HHHHHHHCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DVKRDEPQQGAHMAGWRKMLYITMSRNQADRTRVFRIPRTRAVVMGEAVAL
HCCCCCCCCCCHHHCCEEEEEEEECCCCCCCHHEEECCCCCEEECCHHHCH
>Mature Secondary Structure
MIRSHERQAVAKATQPIVDREPIRSMKPGLALAALGIVFGDIGTSVLYSLQTVFSMENHA
CCCCHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VRPTHGDVMGIISMIFWSILLVVCVKYVIFVMRADNDGEGGILALMALVRRLMASHKGTG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
MTALLLGIVGAGLFYGDSFITPAISVMSAVEGLTVANPDAEKIVLPASVVILTLLFIVQR
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEHHHHHHHHHHHHHHH
RGTEVIGKAFGPVMATWFLTLAALGIPWIIHHPVIITALSPHWAILFSIERPAMAFIAMG
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCEEEEEEECCHHHHHHHHH
AVVLTITGAEALYADMGHVGAPSIRLAWFGLVLPCLLINYLGQGAMILSHPDWIDNPFFR
HHEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCE
MAPDWATIPLVTIATMATVIASQAVISGAFSMSSEAARLGLLPRLGVRHTSKSEGGQIYI
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCEEEE
PEVNWTLFIGVLALILIFQTSSKLATAYGLAVTGTFLLTTSLFLVLAHRAWHWPMWALIF
ECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FGVIVGGVELSIFSANLLKIASGGWIPLLFATIVVIIMTTWRRGTAYIAKQRQDDEGPLD
HHHHHCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHH
DFLNWMHETKPTRVPGLAVYPHPGRATTPLALLNNLRFNHVLHEHNIIISIVVENVPHVR
HHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHCCHHHHHHHHCCEEEEEEECCCCCHH
HVNRIEKVDLGRPTDGITYIACHVGFTDSQDVPKALALAAAKCPWLKDHLDEAIYYLSLV
HHHHHHHCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DVKRDEPQQGAHMAGWRKMLYITMSRNQADRTRVFRIPRTRAVVMGEAVAL
HCCCCCCCCCCHHHCCEEEEEEEECCCCCCCHHEEECCCCCEEECCHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA