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The map label for this gene is idi

Identifier: 50843553

GI number: 50843553

Start: 2289317

End: 2289916

Strand: Reverse

Name: idi

Synonym: PPA2115

Alternate gene names: 50843553

Gene position: 2289916-2289317 (Counterclockwise)

Preceding gene: 50843566

Following gene: 50843547

Centisome position: 89.44

GC content: 60.5

Gene sequence:

>600_bases
ATGAGTCATCATGATGGCGAGAACGAGGGGACGAGCGCGGATTCCGGTTATGACGATTTCGTTATCCTGCTTGACGACGA
CGGCAACCACATTGGAACCGCTCCCCGGGCGACCGTCCACAGTCAACATACCCCTAGGCATCTCGCCTTCTCGTGCCACG
TTCTTGACGTAGGCGGTCGGGTACTTGTGACCCGGCGCGCTTTGACGAAGGTGGCGTGGCCAGGGGTGTGGACCAACACC
TGTTGTGGGCATCCACGTGTAGGGGAGACGATTATTGACGCCGCCGTGCGTCGTACTCACCAGGAACTCGGACTCGACCT
TGATCCGCGTCGGATGCGCGTCGTGCTACCAGATTTCTCCTATCGCGCCACCGACTCCGGAGGCATCGTGGAGGACGAGT
TCTGTCCGGTTGTTGTTGCCCGATTGTCCCTGCCAGAGGAGCTCGTCGAACTTAACCCAGACCCTGACGAGGTGGAGGAG
GTAGCCTGGGTTGGTTGGCAGGACATGTATGACTTGGCCCGGTCAATGCCGGCCCTGCTGAGTCCCTGGGCCGTCGAACA
GATGCTGGAGTTTGGGCCCGATCTTCCCGTGGTGCGCTGA

Upstream 100 bases:

>100_bases
CAGCGTCTCAATCGTGCCTAGGAGGCGACATTGGGCCAATATCGTCAAGCTACAGCGTATTCGACTTCGCGGGACTCGCG
GTTATTGGTAACTTGACGTC

Downstream 100 bases:

>100_bases
CCTTCACTACACCGAGGTGAGAACCTCGCCGTGGTCTGGCCATGCAGCCAGCATCGACGCTGACACGTGACAGACTACCA
ATTGTTCACAAGAGTCGACG

Product: isopentenyl-diphosphate delta-isomerase

Products: NA

Alternate protein names: IPP isomerase; IPP:DMAPP isomerase; Isopentenyl pyrophosphate isomerase

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSHHDGENEGTSADSGYDDFVILLDDDGNHIGTAPRATVHSQHTPRHLAFSCHVLDVGGRVLVTRRALTKVAWPGVWTNT
CCGHPRVGETIIDAAVRRTHQELGLDLDPRRMRVVLPDFSYRATDSGGIVEDEFCPVVVARLSLPEELVELNPDPDEVEE
VAWVGWQDMYDLARSMPALLSPWAVEQMLEFGPDLPVVR

Sequences:

>Translated_199_residues
MSHHDGENEGTSADSGYDDFVILLDDDGNHIGTAPRATVHSQHTPRHLAFSCHVLDVGGRVLVTRRALTKVAWPGVWTNT
CCGHPRVGETIIDAAVRRTHQELGLDLDPRRMRVVLPDFSYRATDSGGIVEDEFCPVVVARLSLPEELVELNPDPDEVEE
VAWVGWQDMYDLARSMPALLSPWAVEQMLEFGPDLPVVR
>Mature_198_residues
SHHDGENEGTSADSGYDDFVILLDDDGNHIGTAPRATVHSQHTPRHLAFSCHVLDVGGRVLVTRRALTKVAWPGVWTNTC
CGHPRVGETIIDAAVRRTHQELGLDLDPRRMRVVLPDFSYRATDSGGIVEDEFCPVVVARLSLPEELVELNPDPDEVEEV
AWVGWQDMYDLARSMPALLSPWAVEQMLEFGPDLPVVR

Specific function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)

COG id: COG1443

COG function: function code I; Isopentenyldiphosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Homo sapiens, GI40018633, Length=162, Percent_Identity=29.0123456790123, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1789255, Length=169, Percent_Identity=44.3786982248521, Blast_Score=139, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6325140, Length=211, Percent_Identity=27.4881516587678, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281362205, Length=180, Percent_Identity=30, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24648688, Length=180, Percent_Identity=30, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IDI_PROAC (Q6A5Z1)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056780.1
- ProteinModelPortal:   Q6A5Z1
- SMR:   Q6A5Z1
- GeneID:   2932607
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA2115
- NMPDR:   fig|267747.1.peg.2057
- HOGENOM:   HBG416977
- OMA:   ALSKKTW
- ProtClustDB:   PRK03759
- BioCyc:   PACN267747:PPA2115-MONOMER
- BRENDA:   5.3.3.2
- GO:   GO:0005737
- HAMAP:   MF_00202
- InterPro:   IPR011876
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- PANTHER:   PTHR10885
- PIRSF:   PIRSF018427
- TIGRFAMs:   TIGR02150

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: =5.3.3.2

Molecular weight: Translated: 22101; Mature: 21970

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS51462 NUDIX

Important sites: ACT_SITE 82-82 ACT_SITE 133-133

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHHDGENEGTSADSGYDDFVILLDDDGNHIGTAPRATVHSQHTPRHLAFSCHVLDVGGR
CCCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCEEEEEEEEEECCCE
VLVTRRALTKVAWPGVWTNTCCGHPRVGETIIDAAVRRTHQELGLDLDPRRMRVVLPDFS
EEEHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
YRATDSGGIVEDEFCPVVVARLSLPEELVELNPDPDEVEEVAWVGWQDMYDLARSMPALL
EEECCCCCEECCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
SPWAVEQMLEFGPDLPVVR
CHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SHHDGENEGTSADSGYDDFVILLDDDGNHIGTAPRATVHSQHTPRHLAFSCHVLDVGGR
CCCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCEEEEEEEEEECCCE
VLVTRRALTKVAWPGVWTNTCCGHPRVGETIIDAAVRRTHQELGLDLDPRRMRVVLPDFS
EEEHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
YRATDSGGIVEDEFCPVVVARLSLPEELVELNPDPDEVEEVAWVGWQDMYDLARSMPALL
EEECCCCCEECCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
SPWAVEQMLEFGPDLPVVR
CHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA