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The map label for this gene is rlmG [H]

Identifier: 50843494

GI number: 50843494

Start: 2226037

End: 2227041

Strand: Direct

Name: rlmG [H]

Synonym: PPA2050

Alternate gene names: 50843494

Gene position: 2226037-2227041 (Clockwise)

Preceding gene: 50843489

Following gene: 50843495

Centisome position: 86.95

GC content: 63.88

Gene sequence:

>1005_bases
ATGGATGCTGCCACCCGGGACCCCGTTGACGAGCTCATCGCCGCCGAATCGCCGCACGCCGACTCAGTGTGGGTGTTGGG
GCGTCCTTCCTTGATGCATATGGCCGAGGGACGGGTTGCGGCGTGGGCTGATGACTGCCGCGATCTCGCCGACATCCCTG
AAGCCATCCGCCTCAACCCCTTAACCGCAGGCGACGTTTCAGACAGCCCCGTGGTGTGGATGGGCCTGCCAGCCAGCCTC
GACGAACTCGACGAACTGTTAGGAACGCTGTGGCGCATCCTTGGCCCCGATGCCCATATCGTCGCCGGTGGGCGCATCAA
GCACATGAGCCGGTCGATGAATGACGTCGCCGCCCGCTGGTTTAACGAGGTCCACGCCAGCCTCGGGGTGCGCAAAGCCC
GTGTGCTGCACTTCTCGTCACCTCGGCAGCGCCCCGCCATCACCGGTACATGGCCGCGCACCAACACCGTCAACGGATTG
ACGATCCGAGCCCACGGAGGTGTCTTCCACACCGCCGGAGTCGACGCCGGAACCTCCCTGCTACTCGACTACCTCGACGC
CATCGCAGCCGACGTCCACTCCGACGCCGTCGATCTGGGGTGCGGGAATGGTGTCATCTCCGCCCATTTGGCGCGACTGC
TCCCCCAGGCCACGATTCACGCTACCGACGTGTCATGGCAAGCCATTGATTCCACCCATCTCACCGCTCAGGCGAACCAG
CTCGACATCGTCACTCATTGGTGCGATGGTCTAGTCGATATACCCAATGAGAGCGTCGACGCCGTTGTCACCAATCCGCC
CTTCCACCGTGGCACCGCCCAGGATCACGCCCCGACCCTGGCCATGCTGGCTGACGCCGCACGCGTGCTACGCCCCGGCG
GGACTCTGTGGTGTGTATACAACAACCACCTGCCGTGGGCGTCTCATGTCCAGCGCACTGTTGGGCCGACCCACCAAGTC
GTGCGGAATCGTCGATACACCGTCATCCGAACAGTGCGTCGATAA

Upstream 100 bases:

>100_bases
AACATCCCAACAAGACAATGTTAACGTTACCATCAGCGCTTACTGACAGCTCCGAACAGCATCGCCGAGTCGGCCCCACC
CGATCTGGGAGACTGCCACC

Downstream 100 bases:

>100_bases
GCCGAAAGCCCTCAAGCCCGCACCGCGCCAAAGGCCGTGACCTCGACCAAACCCGCCAAAACGCACCTACCGTAGTCTCA
TGAATTCTCGCGTCATCCTC

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m2G1835 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmG [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MDAATRDPVDELIAAESPHADSVWVLGRPSLMHMAEGRVAAWADDCRDLADIPEAIRLNPLTAGDVSDSPVVWMGLPASL
DELDELLGTLWRILGPDAHIVAGGRIKHMSRSMNDVAARWFNEVHASLGVRKARVLHFSSPRQRPAITGTWPRTNTVNGL
TIRAHGGVFHTAGVDAGTSLLLDYLDAIAADVHSDAVDLGCGNGVISAHLARLLPQATIHATDVSWQAIDSTHLTAQANQ
LDIVTHWCDGLVDIPNESVDAVVTNPPFHRGTAQDHAPTLAMLADAARVLRPGGTLWCVYNNHLPWASHVQRTVGPTHQV
VRNRRYTVIRTVRR

Sequences:

>Translated_334_residues
MDAATRDPVDELIAAESPHADSVWVLGRPSLMHMAEGRVAAWADDCRDLADIPEAIRLNPLTAGDVSDSPVVWMGLPASL
DELDELLGTLWRILGPDAHIVAGGRIKHMSRSMNDVAARWFNEVHASLGVRKARVLHFSSPRQRPAITGTWPRTNTVNGL
TIRAHGGVFHTAGVDAGTSLLLDYLDAIAADVHSDAVDLGCGNGVISAHLARLLPQATIHATDVSWQAIDSTHLTAQANQ
LDIVTHWCDGLVDIPNESVDAVVTNPPFHRGTAQDHAPTLAMLADAARVLRPGGTLWCVYNNHLPWASHVQRTVGPTHQV
VRNRRYTVIRTVRR
>Mature_334_residues
MDAATRDPVDELIAAESPHADSVWVLGRPSLMHMAEGRVAAWADDCRDLADIPEAIRLNPLTAGDVSDSPVVWMGLPASL
DELDELLGTLWRILGPDAHIVAGGRIKHMSRSMNDVAARWFNEVHASLGVRKARVLHFSSPRQRPAITGTWPRTNTVNGL
TIRAHGGVFHTAGVDAGTSLLLDYLDAIAADVHSDAVDLGCGNGVISAHLARLLPQATIHATDVSWQAIDSTHLTAQANQ
LDIVTHWCDGLVDIPNESVDAVVTNPPFHRGTAQDHAPTLAMLADAARVLRPGGTLWCVYNNHLPWASHVQRTVGPTHQV
VRNRRYTVIRTVRR

Specific function: Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA [H]

COG id: COG2813

COG function: function code J; 16S RNA G1207 methylase RsmC

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmG family [H]

Homologues:

Organism=Escherichia coli, GI87082206, Length=298, Percent_Identity=27.1812080536913, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790830, Length=277, Percent_Identity=28.8808664259928, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR017237
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.174 [H]

Molecular weight: Translated: 36251; Mature: 36251

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAATRDPVDELIAAESPHADSVWVLGRPSLMHMAEGRVAAWADDCRDLADIPEAIRLNP
CCCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHCCCEEECHHHHHHHHCCCHHHEECC
LTAGDVSDSPVVWMGLPASLDELDELLGTLWRILGPDAHIVAGGRIKHMSRSMNDVAARW
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
FNEVHASLGVRKARVLHFSSPRQRPAITGTWPRTNTVNGLTIRAHGGVFHTAGVDAGTSL
HHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCCCCCEEEEECCCEEEECCCCCHHHH
LLDYLDAIAADVHSDAVDLGCGNGVISAHLARLLPQATIHATDVSWQAIDSTHLTAQANQ
HHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCEEEECCCCEEEECCCEEEECCCC
LDIVTHWCDGLVDIPNESVDAVVTNPPFHRGTAQDHAPTLAMLADAARVLRPGGTLWCVY
EEHHHHHHCCCEECCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEE
NNHLPWASHVQRTVGPTHQVVRNRRYTVIRTVRR
CCCCCHHHHHHHHCCHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure
MDAATRDPVDELIAAESPHADSVWVLGRPSLMHMAEGRVAAWADDCRDLADIPEAIRLNP
CCCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHCCCEEECHHHHHHHHCCCHHHEECC
LTAGDVSDSPVVWMGLPASLDELDELLGTLWRILGPDAHIVAGGRIKHMSRSMNDVAARW
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHH
FNEVHASLGVRKARVLHFSSPRQRPAITGTWPRTNTVNGLTIRAHGGVFHTAGVDAGTSL
HHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCCCCCEEEEECCCEEEECCCCCHHHH
LLDYLDAIAADVHSDAVDLGCGNGVISAHLARLLPQATIHATDVSWQAIDSTHLTAQANQ
HHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCEEEECCCCEEEECCCEEEECCCC
LDIVTHWCDGLVDIPNESVDAVVTNPPFHRGTAQDHAPTLAMLADAARVLRPGGTLWCVY
EEHHHHHHCCCEECCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEE
NNHLPWASHVQRTVGPTHQVVRNRRYTVIRTVRR
CCCCCHHHHHHHHCCHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA