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The map label for this gene is aer [H]

Identifier: 50843455

GI number: 50843455

Start: 2181891

End: 2183249

Strand: Reverse

Name: aer [H]

Synonym: PPA2009

Alternate gene names: 50843455

Gene position: 2183249-2181891 (Counterclockwise)

Preceding gene: 50843457

Following gene: 50843454

Centisome position: 85.27

GC content: 63.87

Gene sequence:

>1359_bases
ATGTCTCGACCTGAACCGACCGGAGAGAACCGTATCGTCGAGCCGGAAGAGATCTTCTTCTCGACTACCGATGCCAAAGG
GGTCATAGAGAAAGCCAACTCGGTTTTCGTAGACATCTCCCGGTACTCCTGGGATGACCTCATCGGAGCGCCTCATAACA
TTATTCGTCACCCGATGATGCCCGGTGCGGCATTCCTCGCCATGTGGACGACAATCAAAACCGGGGAACCTTTTTGCGCC
TACGTCCACAACCTCGCTGCTGATGGTGCCACCTACACGGTGCTGGCCACCGTCGTGCCGTTGGGGGAGGGCTACCTGTC
GGTGCGCGTCACCCCGCAGGTGCCCGAGATGCTTCAGGCGGCCGAGACCGTCTACCAGGCGGGTCGTGACGCCGAGTGGA
TTGCCGGTGAACAGGGATGCGGTGCTCCTGAACGAGCCCGCCGTGGTCTTGATGCCGTCAAGACGGCCCTCGAACAGGCC
GGATACCCCGACTACGGGACGTTCATGCGCAAGGCGTTGGTTCAGGAGGTGTCGGTACGTCGGCGGCAGCACCGTGCCTG
CCGTGGCATGGTTGACGAGACGACTTTGGGACAGCTGTCGAGCCAGGTCAACCGGGCTCGACAGTTGGTCGAGACCTGGC
TGGAGACCTTCGACGGGCTAAGCGACCTCTCGTCCAAAGCCGGTCGGACCGCGCGCACCCTGAGTAAGGCGATGACCGAA
TCGCAGCGCACTGCTGACGTCATTACTGATTCCCGTGAAGCTACTGAGGCGTCGTTGCGGCCCTTGGTGACTGTCCTCAC
CCTGTGGAGCCGGATGGACGCCGAGATAGCGCCGCTGGTCAACGGGGTAGTCGCCGACCTCGACGCCATGGCTACCAGCG
CGGATCTCACGAGTTTCGGCCTGGCGGTGGCCCACATCCAGGTCGAGTCGACCCGCAGCTTTGTTTCCGAGCTGTGGGCC
GAGGTGGACGGTTGGCAACGTGCCCTCCCCGCCATCGATGACCTTTCTCGGGCTGTGGAGGAAGCCATGTCGGAGGCGAA
CCGTCGCCTCGACGAGGTGCGCGACTTGGCCGATCGCGCCGCGTCCCGCACCCAGGAGCTAGCTGATCTGATGGCGATGC
CGACCGCCCTGCTCACCAGTTGGCAGCAGATGGCCAGCCAACGGGAGCTATCGGCCGGGGTGGCTGATCTCGTTCCGCGG
GTGGAGGAGCAGATCGGCGCCAGCCAGGCGATGGCCGCTGAGCTGACCGACGTCGTTGCTGGGCTGCACAAACTCGCAGA
CGCCTCGAACGAGGAATTGGACGTCTCGGTGCTGGCTGAGATCCGTCGTCTCGGGGCCGAGGTGGCGGCCGGACGCTGA

Upstream 100 bases:

>100_bases
AATCCTCTGGCCGTTGGGCGGTGGCGGCGGCGACTATGTACATGGTGAGATGACGAGGACTTCCTTGAACCACACATACA
CATACTGACCAAGGAGGGCC

Downstream 100 bases:

>100_bases
ACCACGCCGGAGTCCGGCCCATGGTTGGGTCGGACTATCAGCAGCAACGCTCTCGACATATGCGTTTTTCCTCGGATAAA
ACGGCGGTCCCGTTCGGTGC

Product: putative aerotaxis sensor receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSRPEPTGENRIVEPEEIFFSTTDAKGVIEKANSVFVDISRYSWDDLIGAPHNIIRHPMMPGAAFLAMWTTIKTGEPFCA
YVHNLAADGATYTVLATVVPLGEGYLSVRVTPQVPEMLQAAETVYQAGRDAEWIAGEQGCGAPERARRGLDAVKTALEQA
GYPDYGTFMRKALVQEVSVRRRQHRACRGMVDETTLGQLSSQVNRARQLVETWLETFDGLSDLSSKAGRTARTLSKAMTE
SQRTADVITDSREATEASLRPLVTVLTLWSRMDAEIAPLVNGVVADLDAMATSADLTSFGLAVAHIQVESTRSFVSELWA
EVDGWQRALPAIDDLSRAVEEAMSEANRRLDEVRDLADRAASRTQELADLMAMPTALLTSWQQMASQRELSAGVADLVPR
VEEQIGASQAMAAELTDVVAGLHKLADASNEELDVSVLAEIRRLGAEVAAGR

Sequences:

>Translated_452_residues
MSRPEPTGENRIVEPEEIFFSTTDAKGVIEKANSVFVDISRYSWDDLIGAPHNIIRHPMMPGAAFLAMWTTIKTGEPFCA
YVHNLAADGATYTVLATVVPLGEGYLSVRVTPQVPEMLQAAETVYQAGRDAEWIAGEQGCGAPERARRGLDAVKTALEQA
GYPDYGTFMRKALVQEVSVRRRQHRACRGMVDETTLGQLSSQVNRARQLVETWLETFDGLSDLSSKAGRTARTLSKAMTE
SQRTADVITDSREATEASLRPLVTVLTLWSRMDAEIAPLVNGVVADLDAMATSADLTSFGLAVAHIQVESTRSFVSELWA
EVDGWQRALPAIDDLSRAVEEAMSEANRRLDEVRDLADRAASRTQELADLMAMPTALLTSWQQMASQRELSAGVADLVPR
VEEQIGASQAMAAELTDVVAGLHKLADASNEELDVSVLAEIRRLGAEVAAGR
>Mature_451_residues
SRPEPTGENRIVEPEEIFFSTTDAKGVIEKANSVFVDISRYSWDDLIGAPHNIIRHPMMPGAAFLAMWTTIKTGEPFCAY
VHNLAADGATYTVLATVVPLGEGYLSVRVTPQVPEMLQAAETVYQAGRDAEWIAGEQGCGAPERARRGLDAVKTALEQAG
YPDYGTFMRKALVQEVSVRRRQHRACRGMVDETTLGQLSSQVNRARQLVETWLETFDGLSDLSSKAGRTARTLSKAMTES
QRTADVITDSREATEASLRPLVTVLTLWSRMDAEIAPLVNGVVADLDAMATSADLTSFGLAVAHIQVESTRSFVSELWAE
VDGWQRALPAIDDLSRAVEEAMSEANRRLDEVRDLADRAASRTQELADLMAMPTALLTSWQQMASQRELSAGVADLVPRV
EEQIGASQAMAAELTDVVAGLHKLADASNEELDVSVLAEIRRLGAEVAAGR

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=141, Percent_Identity=40.4255319148936, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 49191; Mature: 49060

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPEPTGENRIVEPEEIFFSTTDAKGVIEKANSVFVDISRYSWDDLIGAPHNIIRHPMM
CCCCCCCCCCCCCCHHHHHEECCCHHHHHHHCCCEEEEEHHCCHHHHCCCCHHHHHCCCC
PGAAFLAMWTTIKTGEPFCAYVHNLAADGATYTVLATVVPLGEGYLSVRVTPQVPEMLQA
CHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
AETVYQAGRDAEWIAGEQGCGAPERARRGLDAVKTALEQAGYPDYGTFMRKALVQEVSVR
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RRQHRACRGMVDETTLGQLSSQVNRARQLVETWLETFDGLSDLSSKAGRTARTLSKAMTE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHH
SQRTADVITDSREATEASLRPLVTVLTLWSRMDAEIAPLVNGVVADLDAMATSADLTSFG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVAHIQVESTRSFVSELWAEVDGWQRALPAIDDLSRAVEEAMSEANRRLDEVRDLADRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASRTQELADLMAMPTALLTSWQQMASQRELSAGVADLVPRVEEQIGASQAMAAELTDVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHH
GLHKLADASNEELDVSVLAEIRRLGAEVAAGR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRPEPTGENRIVEPEEIFFSTTDAKGVIEKANSVFVDISRYSWDDLIGAPHNIIRHPMM
CCCCCCCCCCCCCHHHHHEECCCHHHHHHHCCCEEEEEHHCCHHHHCCCCHHHHHCCCC
PGAAFLAMWTTIKTGEPFCAYVHNLAADGATYTVLATVVPLGEGYLSVRVTPQVPEMLQA
CHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
AETVYQAGRDAEWIAGEQGCGAPERARRGLDAVKTALEQAGYPDYGTFMRKALVQEVSVR
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RRQHRACRGMVDETTLGQLSSQVNRARQLVETWLETFDGLSDLSSKAGRTARTLSKAMTE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHH
SQRTADVITDSREATEASLRPLVTVLTLWSRMDAEIAPLVNGVVADLDAMATSADLTSFG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVAHIQVESTRSFVSELWAEVDGWQRALPAIDDLSRAVEEAMSEANRRLDEVRDLADRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASRTQELADLMAMPTALLTSWQQMASQRELSAGVADLVPRVEEQIGASQAMAAELTDVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHH
GLHKLADASNEELDVSVLAEIRRLGAEVAAGR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]