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The map label for this gene is nagD [H]

Identifier: 50843403

GI number: 50843403

Start: 2115351

End: 2116169

Strand: Reverse

Name: nagD [H]

Synonym: PPA1954

Alternate gene names: 50843403

Gene position: 2116169-2115351 (Counterclockwise)

Preceding gene: 50843404

Following gene: 50843400

Centisome position: 82.65

GC content: 58.85

Gene sequence:

>819_bases
ATGCACCGAGGTCGGTTGACGATCGATAAGCTAGGGGCTATGAGAGATCCTGCAGACATCGAGTGCTGGCTGACCGACAT
GGACGGCGTGCTCGTCCACGAGAACCATGAGGTGCCTGGCGCCAGCGATCTCATTAATCGTTGGGTTGACACCTCGAAGC
GATTCCTGGTGCTGACCAACAACTCCATCTTCACCCCGCGTGACCTGGCTGCCCGGATGCAGGCTTCTGGTTTGACGGTG
CCGGAGGACAATATTTGGACTTCCGCCTTGGCTACCGCCCATTTCCTAGCCGACCAGCAGCCCGGCGCGCGCCTATACGT
TATTGGCGAGGCTGGCCTGACGACGGCCCTGCACGAGGCCGGGTTTATCCTCACCGACATCGACCCTGACTACGTCGTCC
TCGGAGAGACTCGTACCTACTCCTTTGAGGCCATTACCCGGGCCGTTCGATTCATCGTCGACGGTGCCAGGTTTATCTGC
ACTAACCCCGACGCGACTGGCCCCAGCAAAGAGGGCCCGCTGCCTGCCACCGGTGCCGTCGCCGCGATGATCGAGGCTGC
CTCGAAGCACAAGCCATACATCGTCGGAAAACCGAACCCGATGATGTTCCGCTCGGCTTTGAATCGCATTGAGGCCCACT
CTGAGACCACCGCCATGATCGGTGACCGAATGGATACCGACATGGTTGCTGGTATGGAAGCTGGGTTGCTGACTGTCCTG
GTGCTCTCGGGTATCACCAAGCGTGAAGAAGTCGAACAGTACCCCTACCGTCCTAACATCATTCTTGATTCGGTAGCCGA
CCTCAACGAGCTCATCTGA

Upstream 100 bases:

>100_bases
ACACTGCCCAAGACTGGTGTCTGAGCATATGAGGTGAGATGGTTCGCCCCGTACGACATCACGGCTAGGTGATTGTAGGT
GCGTTCAGGTTCTGCCCGTA

Downstream 100 bases:

>100_bases
AACATCGACGAAATGCTGCGACGGCGGTGAACGTGACGTTCGCCGCCGTCGTGTCGTATCCGGACGTTCCTGGGGCTTTT
ACACCTGCCAGGGGATGACG

Product: sugar phosphatase/hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MHRGRLTIDKLGAMRDPADIECWLTDMDGVLVHENHEVPGASDLINRWVDTSKRFLVLTNNSIFTPRDLAARMQASGLTV
PEDNIWTSALATAHFLADQQPGARLYVIGEAGLTTALHEAGFILTDIDPDYVVLGETRTYSFEAITRAVRFIVDGARFIC
TNPDATGPSKEGPLPATGAVAAMIEAASKHKPYIVGKPNPMMFRSALNRIEAHSETTAMIGDRMDTDMVAGMEAGLLTVL
VLSGITKREEVEQYPYRPNIILDSVADLNELI

Sequences:

>Translated_272_residues
MHRGRLTIDKLGAMRDPADIECWLTDMDGVLVHENHEVPGASDLINRWVDTSKRFLVLTNNSIFTPRDLAARMQASGLTV
PEDNIWTSALATAHFLADQQPGARLYVIGEAGLTTALHEAGFILTDIDPDYVVLGETRTYSFEAITRAVRFIVDGARFIC
TNPDATGPSKEGPLPATGAVAAMIEAASKHKPYIVGKPNPMMFRSALNRIEAHSETTAMIGDRMDTDMVAGMEAGLLTVL
VLSGITKREEVEQYPYRPNIILDSVADLNELI
>Mature_272_residues
MHRGRLTIDKLGAMRDPADIECWLTDMDGVLVHENHEVPGASDLINRWVDTSKRFLVLTNNSIFTPRDLAARMQASGLTV
PEDNIWTSALATAHFLADQQPGARLYVIGEAGLTTALHEAGFILTDIDPDYVVLGETRTYSFEAITRAVRFIVDGARFIC
TNPDATGPSKEGPLPATGAVAAMIEAASKHKPYIVGKPNPMMFRSALNRIEAHSETTAMIGDRMDTDMVAGMEAGLLTVL
VLSGITKREEVEQYPYRPNIILDSVADLNELI

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI10092677, Length=271, Percent_Identity=31.7343173431734, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI108796653, Length=303, Percent_Identity=27.0627062706271, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI14149777, Length=251, Percent_Identity=26.6932270916335, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786890, Length=250, Percent_Identity=44.8, Blast_Score=230, Evalue=7e-62,
Organism=Caenorhabditis elegans, GI17558880, Length=296, Percent_Identity=28.7162162162162, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17562458, Length=279, Percent_Identity=29.3906810035842, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17560956, Length=279, Percent_Identity=29.3906810035842, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193210059, Length=270, Percent_Identity=28.5185185185185, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI86563050, Length=280, Percent_Identity=28.2142857142857, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71984613, Length=273, Percent_Identity=27.8388278388278, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17557870, Length=263, Percent_Identity=25.4752851711027, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319965, Length=284, Percent_Identity=26.4084507042254, Blast_Score=93, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24666141, Length=282, Percent_Identity=28.0141843971631, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24656326, Length=255, Percent_Identity=27.843137254902, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI22026920, Length=260, Percent_Identity=26.5384615384615, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24656330, Length=287, Percent_Identity=26.4808362369338, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24666137, Length=285, Percent_Identity=27.719298245614, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859765, Length=284, Percent_Identity=29.2253521126761, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 29751; Mature: 29751

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRGRLTIDKLGAMRDPADIECWLTDMDGVLVHENHEVPGASDLINRWVDTSKRFLVLTN
CCCCCEEHHHHCCCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEC
NSIFTPRDLAARMQASGLTVPEDNIWTSALATAHFLADQQPGARLYVIGEAGLTTALHEA
CCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHC
GFILTDIDPDYVVLGETRTYSFEAITRAVRFIVDGARFICTNPDATGPSKEGPLPATGAV
CEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHH
AAMIEAASKHKPYIVGKPNPMMFRSALNRIEAHSETTAMIGDRMDTDMVAGMEAGLLTVL
HHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHH
VLSGITKREEVEQYPYRPNIILDSVADLNELI
HHHCCCCHHHHHHCCCCCCEEHHHHHHHHHCC
>Mature Secondary Structure
MHRGRLTIDKLGAMRDPADIECWLTDMDGVLVHENHEVPGASDLINRWVDTSKRFLVLTN
CCCCCEEHHHHCCCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEC
NSIFTPRDLAARMQASGLTVPEDNIWTSALATAHFLADQQPGARLYVIGEAGLTTALHEA
CCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHC
GFILTDIDPDYVVLGETRTYSFEAITRAVRFIVDGARFICTNPDATGPSKEGPLPATGAV
CEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHH
AAMIEAASKHKPYIVGKPNPMMFRSALNRIEAHSETTAMIGDRMDTDMVAGMEAGLLTVL
HHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHH
VLSGITKREEVEQYPYRPNIILDSVADLNELI
HHHCCCCHHHHHHCCCCCCEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]