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The map label for this gene is rpoB

Identifier: 50843338

GI number: 50843338

Start: 2045208

End: 2048687

Strand: Reverse

Name: rpoB

Synonym: PPA1884

Alternate gene names: 50843338

Gene position: 2048687-2045208 (Counterclockwise)

Preceding gene: 50843339

Following gene: 50843337

Centisome position: 80.02

GC content: 59.71

Gene sequence:

>3480_bases
TTGGCCGCCACGCGTACCGCGTCGAAGAACACCAGCGCCATTTCGCCCCAGTCGGGACGAATTTCATTCGCCAAGATTCA
CGAGCCGTTGGAAGTTCCCAACCTTCTCGATCTTCAGGTCGAGTCGTTTAACTGGCTCGTTGGCAACGAGATATGGCAGT
CCCGTGTGGACGCCGCCCTTGCAGAGGGGCGTACCGACATTAATACCAAGTCCGGGCTCGAGGAGATTTTCGAGGAGATC
TCTCCGATCGAGGACTACTCCCAGACGATGTCCCTGTCTTTCCGGGATCACCGTTTCGAAGATCCTAAGCACAGCGTTGA
CGAGTGCAAGGACCGCGACACCACCTACGCAGCCCCACTGTTCGTGACTGCGGAGTTCATGAACAATGAGACCGAGGAGA
TTAAGTCTCAGACGGTCTTTATTGGTGACTTTCCGCTCATGACCTCCAAAGGCACCTTCATTATCAACGGCACTGAGCGT
GTCGTGGTGTCCCAGTTGGTGCGTTCCCCCGGTGTCTACTTTGAAAAGACTGCCGACAAGACCTCCGACAAGGACATCTT
TACCTGTAAGGTGATCCCGTCGCGTGGCGCCTGGCTCGAGTTCGCGATCGACAAGCGTGACACCGTCGGCGTCCGTCTGG
ACCGTAAGCGCAAGCAGAACGTGACCGTCTTCCTTAAGGCCCTCGGTTGGACTGCCGACCGGATCCTCGAGGAGTTCGGC
ACTCATGAGTCGATCCGTCAGACCCTTGAGAAGGACCATGGCGTCGAGACTCAGGATCAAGCTCTCCTTGACATCTACAA
GAAGCTGCGTCCTGGCGAGCCGCCGTCCCGTGACGCCGCGCAGCAGCTGCTCGAGAATTACTACTTCAACCCGAAGCGCT
ACGACCTGGCCAAGGTTGGTCGGTACAAGATCAACAAGAAGCTCGGTCTGTCCCTGCCCTTCGATCAGCAGGTTCTGACG
GTCGACGACATCGTCGCTGCTATCCACTTCGTGTGCGCCCTGCACGAGGGCACCGCGATTCTGCCGCGGGAGGGACAGGA
CGACATCGTCGTTGAGCCCGACGACATTGACCATTTCGGTAACCGTCGTTTGCGTACCGTCGGCGAGCTGATCCAGAACC
AGTTGCGTACCGGTCTGAGCCGTATGGAGCGCGTCGTGCGTGACCGCATGACTACGCAGGACATTGAGGCCATCACCCCG
CAGACTTTGATTAACATCCGCCCAGTGACGGCGGCGATCAAGGAGTTCTTCGGAACCTCCCAGCTGTCGCAGTTCATGGA
TCAGAACAACCCGCTGGCCGAGATGACCCACAAGCGTCGCCTGTCGGCCTTGGGCCCCGGCGGTTTGTCTCGTGACCGTG
CCGGCATGGAGGTCCGTGACGTTCACCCGTCGCACTACGGTCGTATGTGCCCGATTGAGACCCCTGAGGGTCCGAACATT
GGTCTGATTGGTTCGCTGGCTTCCTTCGCTCGCGTCAATGCTTTTGGGTTCATCGAGACCCCATACCGCAAGGTCGTTGA
CGGGCATGTTACCGATGAGGTCGTCTACCTGACCGCTGACGAAGAGGATCGTCACGTCATTGCCCAGGCCAACGCGAAGC
TTGATGACGATGGCCATTTCGCCAACGATCGTGTGCTGGTGCGCCAGCGCCACGGTGAGGCCGACGAGGTTCCCAGCTCC
GAGGTCGACTACATGGATGTGTCCCCGCGCCAGATGGTGTCGGTGGCGTCTGCTCTCATCCCATTCCTCGAGCACGACGA
TGCTTCCCGAGCCCTCATGGGCGCGAATATGCAGCGTCAGGCTGTGCCGCTGGTGCGCACTGAGGCTCCATTCGTCGGAA
CCGGTATGGAATACCGTTGTGCGGTTGACGTCGGTGATGTCACTCTTGCTGAGAAGGCCGGTTCGGTGCTGTCGGTGAGC
GCTGACCTTATCGACATCGCCTGCGACGACGGCACTTACCAGACCTACAAGCTGGAAAAGTTCCGCCGCTCGAATGCCGG
TACCTGCATTAATCAGCGTCCGCTGGTCAAGGTGGGGCAGCGCGTTGAGGTTGGCACCCCGCTGGCCGACGGCCCGTCGA
CCGACAACGGCGAGCTTGCCCTCGGTCGCAATATGTTGGCCGCATTCATGCCTTGGCAAGGCCTCAACTATGAGGACGCC
ATCATTCTGTCCCAGCGGATCGTCTCTGATGACGTTCTCACCTCGATCCACATCGAGGAGCACGAGGTCGACGCTCGTGA
TACCAAGCTGGGTGCTGAGGAGATTACTCGGGATATTCCGAACGTTTCCGAGGATATGCTGGCCAACCTTGACGAGAACG
GCATCGTGCGTATCGGTGCAGAGGTCGGCACTGGCGACATCCTGGTTGGCAAGGTCACTCCGAAGGGCGAGACCGAGCTG
ACCCCTGAGGAGCGTCTGCTGCGCGCGATCTTCGGTGAGAAGGCCCGCGAGGTCCGTGATACTTCCCTTAAGGTTCCTCA
CGGCGAGGAAGGCACTGTCATCGGGGTGCGCATCTTCGACACCGAGAACGGTGACGAGTTGGCGCCGGGCGTTAACCAGA
TGGTTCGCGTCTACGTCGCCCAGAAGCGCAAGATCTCCATCGGTGACAAGCTGGCCGGACGCCACGGTAACAAGGGCGTC
ATCTCGAAGATTCTACCTGTCGAGGACATGCCGTTCCTGCCGGACGGCACCCCTGTCGACATCATCCTCAACCCGTTGGG
TGTGCCCTCCCGAATGAACGTCGGGCAGGTTCTTGAGATGCACCTGGGCTGGATCGCTCACTCCGGCTGGGATATCACCC
AGGCCGAGGGTGATTGGGCCGAGCGTCTGCGCGAGGTTGGCCTCATTGATATTCCTGAGGAATCCCGTCTGGCCACCCCG
GTATTCGACGGTGCCACCGAGCAGGAGATCACCGGTTTGCTGCAGTACGGCCACCCAACCCGCGATGGCGAGATGCTCGT
TGACACCGACGGTAAGGCGACCCTCTTCGATGGCCGTACCGGCGAGCCCTTCCCCTCGAAGGTGGGCGTCGGCTACATGT
ACATGCTGAAGCTGCACCACCTGGTTGACGACAAGATCCACGCCCGTTCCACCGGCCCGTACTCGATGATCACCCAGCAG
CCGCTTGGCGGTAAGGCCCAGTTCGGTGGTCAGCGATTCGGTGAGATGGAAGTGTGGGCCATGGAGGCCTATGGCGCCGC
TTGGGCTTTGCAGGAGCTGCTCACTATCAAGTCCGATGACGTTCCAGGCCGTGTCAAGGTCTATGAGGCGATCGTCAAGG
GCGAGAACATTCCTGAGCCGGGTATCCCTGAATCCTTCAAGGTGCTCGTCAAGGAGATGAAGTCACTCTGCCTGAATGTG
GAGGTGCTCAACTCGGAGGGCCAAGAGATCGACTTGCGCGGCTCTGAGGAAGACACCCGGTCTGGTCTGGGTATCGACAT
TGGGCGTCGTCCTGGTGCCGACAACGCTATGGCCGACTGA

Upstream 100 bases:

>100_bases
GCACCATTGCCAGCGATCGCCCATGCTTGACATGGGCGGTTTGTCATGCCCCCAGACCGGCCGACAGGTCGGTTGTAGGA
GTTCTCGGAAGGACCGCACA

Downstream 100 bases:

>100_bases
CCTGCCCATATGTCGGGGGTGACGGCGTTGCCCCCGACCCCTGAACACAGTCCGTTTGACGGGGGTGGGGACGGGCCCGG
ACAACCCGACTCACACAGAC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1159; Mature: 1158

Protein sequence:

>1159_residues
MAATRTASKNTSAISPQSGRISFAKIHEPLEVPNLLDLQVESFNWLVGNEIWQSRVDAALAEGRTDINTKSGLEEIFEEI
SPIEDYSQTMSLSFRDHRFEDPKHSVDECKDRDTTYAAPLFVTAEFMNNETEEIKSQTVFIGDFPLMTSKGTFIINGTER
VVVSQLVRSPGVYFEKTADKTSDKDIFTCKVIPSRGAWLEFAIDKRDTVGVRLDRKRKQNVTVFLKALGWTADRILEEFG
THESIRQTLEKDHGVETQDQALLDIYKKLRPGEPPSRDAAQQLLENYYFNPKRYDLAKVGRYKINKKLGLSLPFDQQVLT
VDDIVAAIHFVCALHEGTAILPREGQDDIVVEPDDIDHFGNRRLRTVGELIQNQLRTGLSRMERVVRDRMTTQDIEAITP
QTLINIRPVTAAIKEFFGTSQLSQFMDQNNPLAEMTHKRRLSALGPGGLSRDRAGMEVRDVHPSHYGRMCPIETPEGPNI
GLIGSLASFARVNAFGFIETPYRKVVDGHVTDEVVYLTADEEDRHVIAQANAKLDDDGHFANDRVLVRQRHGEADEVPSS
EVDYMDVSPRQMVSVASALIPFLEHDDASRALMGANMQRQAVPLVRTEAPFVGTGMEYRCAVDVGDVTLAEKAGSVLSVS
ADLIDIACDDGTYQTYKLEKFRRSNAGTCINQRPLVKVGQRVEVGTPLADGPSTDNGELALGRNMLAAFMPWQGLNYEDA
IILSQRIVSDDVLTSIHIEEHEVDARDTKLGAEEITRDIPNVSEDMLANLDENGIVRIGAEVGTGDILVGKVTPKGETEL
TPEERLLRAIFGEKAREVRDTSLKVPHGEEGTVIGVRIFDTENGDELAPGVNQMVRVYVAQKRKISIGDKLAGRHGNKGV
ISKILPVEDMPFLPDGTPVDIILNPLGVPSRMNVGQVLEMHLGWIAHSGWDITQAEGDWAERLREVGLIDIPEESRLATP
VFDGATEQEITGLLQYGHPTRDGEMLVDTDGKATLFDGRTGEPFPSKVGVGYMYMLKLHHLVDDKIHARSTGPYSMITQQ
PLGGKAQFGGQRFGEMEVWAMEAYGAAWALQELLTIKSDDVPGRVKVYEAIVKGENIPEPGIPESFKVLVKEMKSLCLNV
EVLNSEGQEIDLRGSEEDTRSGLGIDIGRRPGADNAMAD

Sequences:

>Translated_1159_residues
MAATRTASKNTSAISPQSGRISFAKIHEPLEVPNLLDLQVESFNWLVGNEIWQSRVDAALAEGRTDINTKSGLEEIFEEI
SPIEDYSQTMSLSFRDHRFEDPKHSVDECKDRDTTYAAPLFVTAEFMNNETEEIKSQTVFIGDFPLMTSKGTFIINGTER
VVVSQLVRSPGVYFEKTADKTSDKDIFTCKVIPSRGAWLEFAIDKRDTVGVRLDRKRKQNVTVFLKALGWTADRILEEFG
THESIRQTLEKDHGVETQDQALLDIYKKLRPGEPPSRDAAQQLLENYYFNPKRYDLAKVGRYKINKKLGLSLPFDQQVLT
VDDIVAAIHFVCALHEGTAILPREGQDDIVVEPDDIDHFGNRRLRTVGELIQNQLRTGLSRMERVVRDRMTTQDIEAITP
QTLINIRPVTAAIKEFFGTSQLSQFMDQNNPLAEMTHKRRLSALGPGGLSRDRAGMEVRDVHPSHYGRMCPIETPEGPNI
GLIGSLASFARVNAFGFIETPYRKVVDGHVTDEVVYLTADEEDRHVIAQANAKLDDDGHFANDRVLVRQRHGEADEVPSS
EVDYMDVSPRQMVSVASALIPFLEHDDASRALMGANMQRQAVPLVRTEAPFVGTGMEYRCAVDVGDVTLAEKAGSVLSVS
ADLIDIACDDGTYQTYKLEKFRRSNAGTCINQRPLVKVGQRVEVGTPLADGPSTDNGELALGRNMLAAFMPWQGLNYEDA
IILSQRIVSDDVLTSIHIEEHEVDARDTKLGAEEITRDIPNVSEDMLANLDENGIVRIGAEVGTGDILVGKVTPKGETEL
TPEERLLRAIFGEKAREVRDTSLKVPHGEEGTVIGVRIFDTENGDELAPGVNQMVRVYVAQKRKISIGDKLAGRHGNKGV
ISKILPVEDMPFLPDGTPVDIILNPLGVPSRMNVGQVLEMHLGWIAHSGWDITQAEGDWAERLREVGLIDIPEESRLATP
VFDGATEQEITGLLQYGHPTRDGEMLVDTDGKATLFDGRTGEPFPSKVGVGYMYMLKLHHLVDDKIHARSTGPYSMITQQ
PLGGKAQFGGQRFGEMEVWAMEAYGAAWALQELLTIKSDDVPGRVKVYEAIVKGENIPEPGIPESFKVLVKEMKSLCLNV
EVLNSEGQEIDLRGSEEDTRSGLGIDIGRRPGADNAMAD
>Mature_1158_residues
AATRTASKNTSAISPQSGRISFAKIHEPLEVPNLLDLQVESFNWLVGNEIWQSRVDAALAEGRTDINTKSGLEEIFEEIS
PIEDYSQTMSLSFRDHRFEDPKHSVDECKDRDTTYAAPLFVTAEFMNNETEEIKSQTVFIGDFPLMTSKGTFIINGTERV
VVSQLVRSPGVYFEKTADKTSDKDIFTCKVIPSRGAWLEFAIDKRDTVGVRLDRKRKQNVTVFLKALGWTADRILEEFGT
HESIRQTLEKDHGVETQDQALLDIYKKLRPGEPPSRDAAQQLLENYYFNPKRYDLAKVGRYKINKKLGLSLPFDQQVLTV
DDIVAAIHFVCALHEGTAILPREGQDDIVVEPDDIDHFGNRRLRTVGELIQNQLRTGLSRMERVVRDRMTTQDIEAITPQ
TLINIRPVTAAIKEFFGTSQLSQFMDQNNPLAEMTHKRRLSALGPGGLSRDRAGMEVRDVHPSHYGRMCPIETPEGPNIG
LIGSLASFARVNAFGFIETPYRKVVDGHVTDEVVYLTADEEDRHVIAQANAKLDDDGHFANDRVLVRQRHGEADEVPSSE
VDYMDVSPRQMVSVASALIPFLEHDDASRALMGANMQRQAVPLVRTEAPFVGTGMEYRCAVDVGDVTLAEKAGSVLSVSA
DLIDIACDDGTYQTYKLEKFRRSNAGTCINQRPLVKVGQRVEVGTPLADGPSTDNGELALGRNMLAAFMPWQGLNYEDAI
ILSQRIVSDDVLTSIHIEEHEVDARDTKLGAEEITRDIPNVSEDMLANLDENGIVRIGAEVGTGDILVGKVTPKGETELT
PEERLLRAIFGEKAREVRDTSLKVPHGEEGTVIGVRIFDTENGDELAPGVNQMVRVYVAQKRKISIGDKLAGRHGNKGVI
SKILPVEDMPFLPDGTPVDIILNPLGVPSRMNVGQVLEMHLGWIAHSGWDITQAEGDWAERLREVGLIDIPEESRLATPV
FDGATEQEITGLLQYGHPTRDGEMLVDTDGKATLFDGRTGEPFPSKVGVGYMYMLKLHHLVDDKIHARSTGPYSMITQQP
LGGKAQFGGQRFGEMEVWAMEAYGAAWALQELLTIKSDDVPGRVKVYEAIVKGENIPEPGIPESFKVLVKEMKSLCLNVE
VLNSEGQEIDLRGSEEDTRSGLGIDIGRRPGADNAMAD

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908503, Length=1191, Percent_Identity=23.0058774139379, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI238908505, Length=1116, Percent_Identity=23.2974910394265, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI4505941, Length=398, Percent_Identity=30.9045226130653, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI33469941, Length=540, Percent_Identity=25.1851851851852, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI212286172, Length=540, Percent_Identity=25.1851851851852, Blast_Score=129, Evalue=1e-29,
Organism=Escherichia coli, GI1790419, Length=593, Percent_Identity=58.3473861720067, Blast_Score=694, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=390, Percent_Identity=31.025641025641, Blast_Score=166, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI25144348, Length=471, Percent_Identity=28.8747346072187, Blast_Score=152, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17506623, Length=258, Percent_Identity=32.9457364341085, Blast_Score=114, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324725, Length=390, Percent_Identity=31.5384615384615, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6324781, Length=590, Percent_Identity=24.5762711864407, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6325267, Length=416, Percent_Identity=29.0865384615385, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI17136444, Length=399, Percent_Identity=30.3258145363409, Blast_Score=158, Evalue=3e-38,
Organism=Drosophila melanogaster, GI17647877, Length=442, Percent_Identity=29.6380090497738, Blast_Score=144, Evalue=3e-34,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_PROAC (Q6A6K6)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056565.1
- ProteinModelPortal:   Q6A6K6
- GeneID:   2930970
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1884
- NMPDR:   fig|267747.1.peg.1842
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- ProtClustDB:   PRK00405
- BioCyc:   PACN267747:PPA1884-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 128432; Mature: 128301

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATRTASKNTSAISPQSGRISFAKIHEPLEVPNLLDLQVESFNWLVGNEIWQSRVDAAL
CCCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCEEEEEEECCCEEHHHHHHHHHHHHHH
AEGRTDINTKSGLEEIFEEISPIEDYSQTMSLSFRDHRFEDPKHSVDECKDRDTTYAAPL
HCCCCCCCHHHHHHHHHHHHCCHHHHHHHHEEEECCCCCCCCCCCHHHHHCCCCEEECHH
FVTAEFMNNETEEIKSQTVFIGDFPLMTSKGTFIINGTERVVVSQLVRSPGVYFEKTADK
EEEHHHHCCCHHHHCCCEEEEECCCEEECCCEEEECCCHHHHHHHHHHCCCCEEEECCCC
TSDKDIFTCKVIPSRGAWLEFAIDKRDTVGVRLDRKRKQNVTVFLKALGWTADRILEEFG
CCCCCEEEEEEECCCCCEEEEEECCCCCCCEEECCCCCCCCEEEEEHHCCCHHHHHHHHC
THESIRQTLEKDHGVETQDQALLDIYKKLRPGEPPSRDAAQQLLENYYFNPKRYDLAKVG
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHC
RYKINKKLGLSLPFDQQVLTVDDIVAAIHFVCALHEGTAILPREGQDDIVVEPDDIDHFG
CEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCEECCCCCCCCEEECCCCCCHHC
NRRLRTVGELIQNQLRTGLSRMERVVRDRMTTQDIEAITPQTLINIRPVTAAIKEFFGTS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHEEECHHHHHHHHHHCHH
QLSQFMDQNNPLAEMTHKRRLSALGPGGLSRDRAGMEVRDVHPSHYGRMCPIETPEGPNI
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCE
GLIGSLASFARVNAFGFIETPYRKVVDGHVTDEVVYLTADEEDRHVIAQANAKLDDDGHF
EHHHHHHHHHHHCCEEEECCCHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCC
ANDRVLVRQRHGEADEVPSSEVDYMDVSPRQMVSVASALIPFLEHDDASRALMGANMQRQ
CCCEEEEEECCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHH
AVPLVRTEAPFVGTGMEYRCAVDVGDVTLAEKAGSVLSVSADLIDIACDDGTYQTYKLEK
CCCEEECCCCEEECCCCEEEEEECCCEEEHHHCCCEEEEECCEEEEEECCCCCEEEEHHH
FRRSNAGTCINQRPLVKVGQRVEVGTPLADGPSTDNGELALGRNMLAAFMPWQGLNYEDA
HHCCCCCCCCCCCCHHHCCCEEECCCCCCCCCCCCCCCEEECHHHHHHHCCCCCCCCCCH
IILSQRIVSDDVLTSIHIEEHEVDARDTKLGAEEITRDIPNVSEDMLANLDENGIVRIGA
HHHHHHHHCCHHHEEEEEECCCCCCHHHHCCHHHHHHHCCCCCHHHHHCCCCCCEEEEEC
EVGTGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGEEGTVIGVRIFD
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCEEEEEEEE
TENGDELAPGVNQMVRVYVAQKRKISIGDKLAGRHGNKGVISKILPVEDMPFLPDGTPVD
CCCCCCCCCCHHHHHHHHHHHCCEECCCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCE
IILNPLGVPSRMNVGQVLEMHLGWIAHSGWDITQAEGDWAERLREVGLIDIPEESRLATP
EEECCCCCCCCCCHHHHHHHHHHHHEECCCCEECCCCHHHHHHHHCCCEECCCCCCCCCC
VFDGATEQEITGLLQYGHPTRDGEMLVDTDGKATLFDGRTGEPFPSKVGVGYMYMLKLHH
CCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCCCHHCCHHHHHHHHHH
LVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWAMEAYGAAWALQELLTIKSDD
HHCCCHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCC
VPGRVKVYEAIVKGENIPEPGIPESFKVLVKEMKSLCLNVEVLNSEGQEIDLRGSEEDTR
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCHHH
SGLGIDIGRRPGADNAMAD
CCCCEECCCCCCCCCCCCC
>Mature Secondary Structure 
AATRTASKNTSAISPQSGRISFAKIHEPLEVPNLLDLQVESFNWLVGNEIWQSRVDAAL
CCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCEEEEEEECCCEEHHHHHHHHHHHHHH
AEGRTDINTKSGLEEIFEEISPIEDYSQTMSLSFRDHRFEDPKHSVDECKDRDTTYAAPL
HCCCCCCCHHHHHHHHHHHHCCHHHHHHHHEEEECCCCCCCCCCCHHHHHCCCCEEECHH
FVTAEFMNNETEEIKSQTVFIGDFPLMTSKGTFIINGTERVVVSQLVRSPGVYFEKTADK
EEEHHHHCCCHHHHCCCEEEEECCCEEECCCEEEECCCHHHHHHHHHHCCCCEEEECCCC
TSDKDIFTCKVIPSRGAWLEFAIDKRDTVGVRLDRKRKQNVTVFLKALGWTADRILEEFG
CCCCCEEEEEEECCCCCEEEEEECCCCCCCEEECCCCCCCCEEEEEHHCCCHHHHHHHHC
THESIRQTLEKDHGVETQDQALLDIYKKLRPGEPPSRDAAQQLLENYYFNPKRYDLAKVG
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHC
RYKINKKLGLSLPFDQQVLTVDDIVAAIHFVCALHEGTAILPREGQDDIVVEPDDIDHFG
CEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCEECCCCCCCCEEECCCCCCHHC
NRRLRTVGELIQNQLRTGLSRMERVVRDRMTTQDIEAITPQTLINIRPVTAAIKEFFGTS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHEEECHHHHHHHHHHCHH
QLSQFMDQNNPLAEMTHKRRLSALGPGGLSRDRAGMEVRDVHPSHYGRMCPIETPEGPNI
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCE
GLIGSLASFARVNAFGFIETPYRKVVDGHVTDEVVYLTADEEDRHVIAQANAKLDDDGHF
EHHHHHHHHHHHCCEEEECCCHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCC
ANDRVLVRQRHGEADEVPSSEVDYMDVSPRQMVSVASALIPFLEHDDASRALMGANMQRQ
CCCEEEEEECCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHH
AVPLVRTEAPFVGTGMEYRCAVDVGDVTLAEKAGSVLSVSADLIDIACDDGTYQTYKLEK
CCCEEECCCCEEECCCCEEEEEECCCEEEHHHCCCEEEEECCEEEEEECCCCCEEEEHHH
FRRSNAGTCINQRPLVKVGQRVEVGTPLADGPSTDNGELALGRNMLAAFMPWQGLNYEDA
HHCCCCCCCCCCCCHHHCCCEEECCCCCCCCCCCCCCCEEECHHHHHHHCCCCCCCCCCH
IILSQRIVSDDVLTSIHIEEHEVDARDTKLGAEEITRDIPNVSEDMLANLDENGIVRIGA
HHHHHHHHCCHHHEEEEEECCCCCCHHHHCCHHHHHHHCCCCCHHHHHCCCCCCEEEEEC
EVGTGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGEEGTVIGVRIFD
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCEEEEEEEE
TENGDELAPGVNQMVRVYVAQKRKISIGDKLAGRHGNKGVISKILPVEDMPFLPDGTPVD
CCCCCCCCCCHHHHHHHHHHHCCEECCCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCE
IILNPLGVPSRMNVGQVLEMHLGWIAHSGWDITQAEGDWAERLREVGLIDIPEESRLATP
EEECCCCCCCCCCHHHHHHHHHHHHEECCCCEECCCCHHHHHHHHCCCEECCCCCCCCCC
VFDGATEQEITGLLQYGHPTRDGEMLVDTDGKATLFDGRTGEPFPSKVGVGYMYMLKLHH
CCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCCCHHCCHHHHHHHHHH
LVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWAMEAYGAAWALQELLTIKSDD
HHCCCHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCC
VPGRVKVYEAIVKGENIPEPGIPESFKVLVKEMKSLCLNVEVLNSEGQEIDLRGSEEDTR
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCHHH
SGLGIDIGRRPGADNAMAD
CCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA