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The map label for this gene is pimC [H]

Identifier: 50843281

GI number: 50843281

Start: 1992782

End: 1993999

Strand: Reverse

Name: pimC [H]

Synonym: PPA1824

Alternate gene names: 50843281

Gene position: 1993999-1992782 (Counterclockwise)

Preceding gene: 50843282

Following gene: 50843280

Centisome position: 77.88

GC content: 64.37

Gene sequence:

>1218_bases
GTGACCACTCTTCGTATCGCTCAGCTCGCCAACTTTGTCGGCCCGGTGTCCGGCGGCATGAAGGTGGCCATCGACGCTCT
CGGAAAGGGGTACGTTGCGGCCGGTCACGAGCGAATCCTGGTAATACCGGGTCCTAAAGACCGCATCACCGAATCAGAAT
CCGGCATCACCGTCGAGATCGCAGCCCCGCGCGTTTCTGCGGGTTACCGCATGATCGCTACGCCGTGGCGAGCCCTCGAC
ATCCTGGACCGCTTCCGCCCCACCTCCATTGAGTCCTCTGACAAGTGGACCCTCACTCCGGCCGCCGGCTGGGCGTCACG
TCGAGGCATCGGATCGGTGCTATTTAGTCACGAACGTCTCGACGACATGCTCACCATGTGGGTACGCAGACAGTTCGGCG
TCGCAGCCGCCGTTGGTGCCCTCAATCGTCGTCTCTCCAAGTCCTTCGACGTCGTCGTCGTCACTTCCGATTACTCTGCG
GGTGAATTCGCCGACACCGGCGCCCGCCTCGTCAAGGTCCCCCTCGGCGTCGACCTAGAAACTTTCAACCCCAACAAACG
TGAACCAGGACTGCCAACTCCGCGCCCCGACGACGTCTTACGACTGTGCTACGTCGGTCGGATGAGCCACGAGAAGAGCC
CCCAGCTGGCCGTCGCTGCTGCTCTCGAATTGCATCGACGCGGGGTCCCACTGCGCCTTGACATGTACGGGGTCGGCCCA
GACACGGATGCCATGAAACCGCAGGCCGGCGACGCTCCGGTCTTCTTCAACGGGTTCGTCGCGGGCCGTGACGAGGTTGC
CCGGCGTTTTGCAGCAGCCGATATTTCGATGTCGGTCTGTCCCGCAGAAACCTTCGGATTAGCCTCCCTGGAGGCGCTCG
CCTGTGGCACCCCGGTCGTCACCGCGAACCGGGGTGGCGCCCACGAGATCGTCGATGTGACGAGCGGGGAAGCCGGCAGC
CCCGACGCCGTGGGCTTAGCCGACGCCACCCAGCGCCTTGCGGCCAGGCTCGGTCCAGAACTGCGGGACGCCGCGCGACA
CCGAGCTGAGCAGTTCACCTGGGACGCCAGCGTGGAGACAATGCTCATGATCCATTCCGAGATTGCTGCACGCCCCGACG
CCAAGCTCTACTGGAAACAGCGCCTCGTGAACCGTCGCAACGCGCGGCGGGACACCCAAGACCCCCTCGCCCCAACCGAC
GACTCCCAGGAGCAGTGA

Upstream 100 bases:

>100_bases
AAAACGCCGGTCCTCACTAGTGAGGACCGGCGTTTATTATGCCTGTGTCCCGAGCCAACCCCTAGTATCGAGGTTCAGAT
TCACCGCATAGGCTAGAGAG

Downstream 100 bases:

>100_bases
TGAGGAAGATCCCACTCGTGCTGGCCGGCGTGGCGGCTGCCGTCACCCCCGTCGTCCTGGCGGCTCCCGGCCCTGAGCCG
GCCATGCCTGACGGCCCCGC

Product: glycosyl transferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTTLRIAQLANFVGPVSGGMKVAIDALGKGYVAAGHERILVIPGPKDRITESESGITVEIAAPRVSAGYRMIATPWRALD
ILDRFRPTSIESSDKWTLTPAAGWASRRGIGSVLFSHERLDDMLTMWVRRQFGVAAAVGALNRRLSKSFDVVVVTSDYSA
GEFADTGARLVKVPLGVDLETFNPNKREPGLPTPRPDDVLRLCYVGRMSHEKSPQLAVAAALELHRRGVPLRLDMYGVGP
DTDAMKPQAGDAPVFFNGFVAGRDEVARRFAAADISMSVCPAETFGLASLEALACGTPVVTANRGGAHEIVDVTSGEAGS
PDAVGLADATQRLAARLGPELRDAARHRAEQFTWDASVETMLMIHSEIAARPDAKLYWKQRLVNRRNARRDTQDPLAPTD
DSQEQ

Sequences:

>Translated_405_residues
MTTLRIAQLANFVGPVSGGMKVAIDALGKGYVAAGHERILVIPGPKDRITESESGITVEIAAPRVSAGYRMIATPWRALD
ILDRFRPTSIESSDKWTLTPAAGWASRRGIGSVLFSHERLDDMLTMWVRRQFGVAAAVGALNRRLSKSFDVVVVTSDYSA
GEFADTGARLVKVPLGVDLETFNPNKREPGLPTPRPDDVLRLCYVGRMSHEKSPQLAVAAALELHRRGVPLRLDMYGVGP
DTDAMKPQAGDAPVFFNGFVAGRDEVARRFAAADISMSVCPAETFGLASLEALACGTPVVTANRGGAHEIVDVTSGEAGS
PDAVGLADATQRLAARLGPELRDAARHRAEQFTWDASVETMLMIHSEIAARPDAKLYWKQRLVNRRNARRDTQDPLAPTD
DSQEQ
>Mature_404_residues
TTLRIAQLANFVGPVSGGMKVAIDALGKGYVAAGHERILVIPGPKDRITESESGITVEIAAPRVSAGYRMIATPWRALDI
LDRFRPTSIESSDKWTLTPAAGWASRRGIGSVLFSHERLDDMLTMWVRRQFGVAAAVGALNRRLSKSFDVVVVTSDYSAG
EFADTGARLVKVPLGVDLETFNPNKREPGLPTPRPDDVLRLCYVGRMSHEKSPQLAVAAALELHRRGVPLRLDMYGVGPD
TDAMKPQAGDAPVFFNGFVAGRDEVARRFAAADISMSVCPAETFGLASLEALACGTPVVTANRGGAHEIVDVTSGEAGSP
DAVGLADATQRLAARLGPELRDAARHRAEQFTWDASVETMLMIHSEIAARPDAKLYWKQRLVNRRNARRDTQDPLAPTDD
SQEQ

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of the alpha-1,6-linked mannose residue of the triacyl phosphatidylinositol dimannoside (Ac3PIM2) to generate triacyl phosphatidylinositol trimannoside (Ac3PIM3) [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 43808; Mature: 43677

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLRIAQLANFVGPVSGGMKVAIDALGKGYVAAGHERILVIPGPKDRITESESGITVEI
CCEEHHHHHHHHHCCCCCCCEEEEECCCCCCEECCCCEEEEECCCCHHCCCCCCCEEEEE
AAPRVSAGYRMIATPWRALDILDRFRPTSIESSDKWTLTPAAGWASRRGIGSVLFSHERL
ECCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHCCHHHHHHHHHHH
DDMLTMWVRRQFGVAAAVGALNRRLSKSFDVVVVTSDYSAGEFADTGARLVKVPLGVDLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCEEE
TFNPNKREPGLPTPRPDDVLRLCYVGRMSHEKSPQLAVAAALELHRRGVPLRLDMYGVGP
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCC
DTDAMKPQAGDAPVFFNGFVAGRDEVARRFAAADISMSVCPAETFGLASLEALACGTPVV
CCCCCCCCCCCCCEEEECEECCHHHHHHHHHHHCCEEEECCCHHCCCHHHHHHHCCCCEE
TANRGGAHEIVDVTSGEAGSPDAVGLADATQRLAARLGPELRDAARHRAEQFTWDASVET
ECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHEEECCCHHH
MLMIHSEIAARPDAKLYWKQRLVNRRNARRDTQDPLAPTDDSQEQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTLRIAQLANFVGPVSGGMKVAIDALGKGYVAAGHERILVIPGPKDRITESESGITVEI
CEEHHHHHHHHHCCCCCCCEEEEECCCCCCEECCCCEEEEECCCCHHCCCCCCCEEEEE
AAPRVSAGYRMIATPWRALDILDRFRPTSIESSDKWTLTPAAGWASRRGIGSVLFSHERL
ECCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHCCHHHHHHHHHHH
DDMLTMWVRRQFGVAAAVGALNRRLSKSFDVVVVTSDYSAGEFADTGARLVKVPLGVDLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCEEE
TFNPNKREPGLPTPRPDDVLRLCYVGRMSHEKSPQLAVAAALELHRRGVPLRLDMYGVGP
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCC
DTDAMKPQAGDAPVFFNGFVAGRDEVARRFAAADISMSVCPAETFGLASLEALACGTPVV
CCCCCCCCCCCCCEEEECEECCHHHHHHHHHHHCCEEEECCCHHCCCHHHHHHHCCCCEE
TANRGGAHEIVDVTSGEAGSPDAVGLADATQRLAARLGPELRDAARHRAEQFTWDASVET
ECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHEEECCCHHH
MLMIHSEIAARPDAKLYWKQRLVNRRNARRDTQDPLAPTDDSQEQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10531227 [H]