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The map label for this gene is bga [H]

Identifier: 50843276

GI number: 50843276

Start: 1984010

End: 1984534

Strand: Direct

Name: bga [H]

Synonym: PPA1819

Alternate gene names: 50843276

Gene position: 1984010-1984534 (Clockwise)

Preceding gene: 50843275

Following gene: 50843277

Centisome position: 77.49

GC content: 61.52

Gene sequence:

>525_bases
ATGACGGAGCCGTCCATGCGCAAAGCCGAGCATCGCCATTCCCTATCCCGGACGATGGCCGCACTGACCGCGGTCGCCTG
TGCCTCAACCTCCCTTGCCGCCACACCTGGCACAGCTGCGGCAACGTCACCGTCACAGACACCGAAAGCGATGTCATCGA
CGCCTTATATCTTCCCGGGCAACGACGGAAAAGCCCACAAAGTCGCTTGGGACAAGCACTCGTTCACCATCGACGGCACC
CGGTTGTCGATCTGGTCCGGGGAACTGCACTACTGGCGCCTCCCCTCCCAGCAAGCGTGGCGCGACGTCATGCGCAAGGC
TCGCGCAAACGGTTTCAACGCCATCTCGTTGTACTTCTTCTGGGGCCTGCACCAAGAATCCGCTGACGGCAAGTTCGACT
TCTCCGGCATTAAAGACATCGACACACTGCTCACCATCGCCGAAGAGGAGGGTCTGTACGTCATCGCCCGGCCCGGCCCC
TACATCAACGCCGAAATCTCCATGGGGGCCTCCCCGCCACCATGA

Upstream 100 bases:

>100_bases
CGAGCTGAGCGCTTGAACTCACGCGTCCATATGCCGCTGATAGCTTCGACTGCGCGTGAGGCACTGAGGCCCCGCGCCCA
CCACGAGGTGGTTCGCCCAC

Downstream 100 bases:

>100_bases
GCAACCAGCCCGGACCTCTGCGTGGCACTGCGAACCTGGCGCGCTCAAAACAATGGCTGCATGCATTCGACGCCATCGCC
CGCAAGCACCAAGTGACGAC

Product: beta-galactosidase

Products: NA

Alternate protein names: Lactase [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MTEPSMRKAEHRHSLSRTMAALTAVACASTSLAATPGTAAATSPSQTPKAMSSTPYIFPGNDGKAHKVAWDKHSFTIDGT
RLSIWSGELHYWRLPSQQAWRDVMRKARANGFNAISLYFFWGLHQESADGKFDFSGIKDIDTLLTIAEEEGLYVIARPGP
YINAEISMGASPPP

Sequences:

>Translated_174_residues
MTEPSMRKAEHRHSLSRTMAALTAVACASTSLAATPGTAAATSPSQTPKAMSSTPYIFPGNDGKAHKVAWDKHSFTIDGT
RLSIWSGELHYWRLPSQQAWRDVMRKARANGFNAISLYFFWGLHQESADGKFDFSGIKDIDTLLTIAEEEGLYVIARPGP
YINAEISMGASPPP
>Mature_173_residues
TEPSMRKAEHRHSLSRTMAALTAVACASTSLAATPGTAAATSPSQTPKAMSSTPYIFPGNDGKAHKVAWDKHSFTIDGTR
LSIWSGELHYWRLPSQQAWRDVMRKARANGFNAISLYFFWGLHQESADGKFDFSGIKDIDTLLTIAEEEGLYVIARPGPY
INAEISMGASPPP

Specific function: Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages [H]

COG id: COG1874

COG function: function code G; Beta-galactosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 35 family [H]

Homologues:

Organism=Homo sapiens, GI164519026, Length=101, Percent_Identity=44.5544554455446, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI31543093, Length=99, Percent_Identity=42.4242424242424, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI119372308, Length=109, Percent_Identity=39.4495412844037, Blast_Score=80, Evalue=8e-16,
Organism=Homo sapiens, GI119372312, Length=106, Percent_Identity=40.5660377358491, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI40255043, Length=114, Percent_Identity=39.4736842105263, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17568491, Length=118, Percent_Identity=37.2881355932203, Blast_Score=76, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI72000600, Length=102, Percent_Identity=40.1960784313725, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582088, Length=102, Percent_Identity=41.1764705882353, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646169, Length=105, Percent_Identity=40, Blast_Score=76, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR019801
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR001944 [H]

Pfam domain/function: PF01301 Glyco_hydro_35 [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 19002; Mature: 18870

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPSMRKAEHRHSLSRTMAALTAVACASTSLAATPGTAAATSPSQTPKAMSSTPYIFPG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEC
NDGKAHKVAWDKHSFTIDGTRLSIWSGELHYWRLPSQQAWRDVMRKARANGFNAISLYFF
CCCCEEEEEECCCCEEECCCEEEEEECCEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEE
WGLHQESADGKFDFSGIKDIDTLLTIAEEEGLYVIARPGPYINAEISMGASPPP
EEECCCCCCCEECCCCCHHHHHHHEEECCCCEEEEECCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
TEPSMRKAEHRHSLSRTMAALTAVACASTSLAATPGTAAATSPSQTPKAMSSTPYIFPG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEC
NDGKAHKVAWDKHSFTIDGTRLSIWSGELHYWRLPSQQAWRDVMRKARANGFNAISLYFF
CCCCEEEEEECCCCEEECCCEEEEEECCEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEE
WGLHQESADGKFDFSGIKDIDTLLTIAEEEGLYVIARPGPYINAEISMGASPPP
EEECCCCCCCEECCCCCHHHHHHHEEECCCCEEEEECCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8563148 [H]