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The map label for this gene is sodA [H]

Identifier: 50843275

GI number: 50843275

Start: 1983161

End: 1983778

Strand: Direct

Name: sodA [H]

Synonym: PPA1818

Alternate gene names: 50843275

Gene position: 1983161-1983778 (Clockwise)

Preceding gene: 50843274

Following gene: 50843276

Centisome position: 77.46

GC content: 58.25

Gene sequence:

>618_bases
ATGGCTGTTTACACCCTTCCCGATCTCGACTACGACTACGGAGCACTGGAGCCCCACATCTCGGGCAAGATCATGGAACT
GCACCATGACAAGCACCACAACACCTACGTTCAGGGTGCCAACACCGCCCTGGAGAAGCTGGCCGAGGCCCGCGAGAAGG
GCGACTTCGGAACCATCAACAAACTCGAAAAGGACCTGGCCTTTAACCTCGGCGGCCACATCAACCACTCCGTGTTCTGG
AAGAACATGTCCCCTCATGGGGGCGGTCGTCCGGAGGGCAACGAACTCGCTGCTGCGATTGACGAGTTCTTCGGTTCCTT
TGACAGCTTCAAAAAGCAGTTTGAGGAAACCGCTAAGGGCGTTCAGGGCTCCGGCTGGGGCATGCTCGTGTGGGACGTGA
TGGGTCAGCGCCTCAACACCATGCAGCTGTTTGACCACCAGGGCAATCTGCCGTCAACCCAGATCCCGGTCGTCCAGCTC
GACATGTGGGAACACGCTTATTACCTGCAGTACCAGAACGTCAAGGCCGACTACGTTACCGCCTGGTGGAACGTCGTTAG
CTGGACCGACGCCGAGCAGCGGTTCGTCAAGGCCCGTTCGATCACCGGTTTGTTCTGA

Upstream 100 bases:

>100_bases
GAATGATGGAAACAGGTTCGGTGTTGTACCACGTAAGCGGCTCTGCCAAGGGCCACGTCATGACGGACGTCGTGACGTAT
CTCGTTCCACAGGAGGAAGA

Downstream 100 bases:

>100_bases
TCCGTAGGCCCTGACGATCCCGTATATTTTTCATCGTCGCTGGCTGCGTCCCCACCCGGACGCGGCCAGTGATGTGCCCA
GGTTGCACCAACGTGTCCGG

Product: superoxide dismutase [Mn/Fe]

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MAVYTLPDLDYDYGALEPHISGKIMELHHDKHHNTYVQGANTALEKLAEAREKGDFGTINKLEKDLAFNLGGHINHSVFW
KNMSPHGGGRPEGNELAAAIDEFFGSFDSFKKQFEETAKGVQGSGWGMLVWDVMGQRLNTMQLFDHQGNLPSTQIPVVQL
DMWEHAYYLQYQNVKADYVTAWWNVVSWTDAEQRFVKARSITGLF

Sequences:

>Translated_205_residues
MAVYTLPDLDYDYGALEPHISGKIMELHHDKHHNTYVQGANTALEKLAEAREKGDFGTINKLEKDLAFNLGGHINHSVFW
KNMSPHGGGRPEGNELAAAIDEFFGSFDSFKKQFEETAKGVQGSGWGMLVWDVMGQRLNTMQLFDHQGNLPSTQIPVVQL
DMWEHAYYLQYQNVKADYVTAWWNVVSWTDAEQRFVKARSITGLF
>Mature_204_residues
AVYTLPDLDYDYGALEPHISGKIMELHHDKHHNTYVQGANTALEKLAEAREKGDFGTINKLEKDLAFNLGGHINHSVFWK
NMSPHGGGRPEGNELAAAIDEFFGSFDSFKKQFEETAKGVQGSGWGMLVWDVMGQRLNTMQLFDHQGNLPSTQIPVVQLD
MWEHAYYLQYQNVKADYVTAWWNVVSWTDAEQRFVKARSITGLF

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=198, Percent_Identity=50, Blast_Score=197, Evalue=5e-51,
Organism=Homo sapiens, GI67782305, Length=198, Percent_Identity=50, Blast_Score=197, Evalue=5e-51,
Organism=Homo sapiens, GI67782309, Length=198, Percent_Identity=38.8888888888889, Blast_Score=135, Evalue=2e-32,
Organism=Escherichia coli, GI1790342, Length=209, Percent_Identity=42.5837320574163, Blast_Score=155, Evalue=1e-39,
Organism=Escherichia coli, GI1787946, Length=186, Percent_Identity=36.0215053763441, Blast_Score=118, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17506561, Length=198, Percent_Identity=47.4747474747475, Blast_Score=178, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17569479, Length=196, Percent_Identity=44.8979591836735, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6321796, Length=201, Percent_Identity=46.2686567164179, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI17136812, Length=199, Percent_Identity=45.2261306532663, Blast_Score=173, Evalue=6e-44,

Paralogues:

None

Copy number: 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 23297; Mature: 23166

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTLPDLDYDYGALEPHISGKIMELHHDKHHNTYVQGANTALEKLAEAREKGDFGTIN
CEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCEECCHHHHHHHHHHHHHCCCCCCHH
KLEKDLAFNLGGHINHSVFWKNMSPHGGGRPEGNELAAAIDEFFGSFDSFKKQFEETAKG
HHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCC
VQGSGWGMLVWDVMGQRLNTMQLFDHQGNLPSTQIPVVQLDMWEHAYYLQYQNVKADYVT
CCCCCCCEEHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCCCHHHH
AWWNVVSWTDAEQRFVKARSITGLF
HHHHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVYTLPDLDYDYGALEPHISGKIMELHHDKHHNTYVQGANTALEKLAEAREKGDFGTIN
EEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCEECCHHHHHHHHHHHHHCCCCCCHH
KLEKDLAFNLGGHINHSVFWKNMSPHGGGRPEGNELAAAIDEFFGSFDSFKKQFEETAKG
HHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCC
VQGSGWGMLVWDVMGQRLNTMQLFDHQGNLPSTQIPVVQLDMWEHAYYLQYQNVKADYVT
CCCCCCCEEHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEECCCCCHHHH
AWWNVVSWTDAEQRFVKARSITGLF
HHHHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8307013; 10231372 [H]