BacMap

Definition	Propionibacterium acnes KPA171202, complete genome.
Accession	NC_006085
Length	2,560,265

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The map label for this gene is fabG

Identifier: 50843271

GI number: 50843271

Start: 1978988

End: 1979749

Strand: Reverse

Name: fabG

Synonym: PPA1815

Alternate gene names: 50843271

Gene position: 1979749-1978988 (Counterclockwise)

Preceding gene: 50843272

Following gene: 50843264

Centisome position: 77.33

GC content: 61.42

Gene sequence:

>762_bases
ATGACTGGATTGCTTGCTGGTCGTACCGCGCTGGTGACCGGTGGAACCGCTGGAATAGGTCGCGGAATCGCGGAGGTACT
CGCACTCCACGGCGCCCGTGTCGCGGTGACTGGTGTGACCGAGGAAAGGTGTGCTCAGGCGCGCGAAGACGGACTCGATG
TGTACCAACTCGACGTGCGGGACAAGAAAGCCTGCATTCGCGTGGTGAATGATGTTGCTGCCGAGTGTGGTGGCCTGTCC
GTGCTCGTTGCTAACGCTGGTGTGTATCCCCAGGTCCGTCTCGCCGATCTTGACGATGACCAAATTGACTTCATCTTTGA
CGTGAATGTGAAAGGGATGATGCACGTCGTCCAAGCGGCAACGCCAGCCCTGCGTGAATCTGGTCGCGGGCGCATCGTGG
TCACGTCGTCGATCACTGGCAACATCACCGGCTACCCGGGGTGGTCCCACTACGGCGCCACCAAGGCGGCACAGATGGGA
TTCATCCGCTCGGCCGCGATGGAGCTGGCAGGCGACAAGATCACCATCAACGCCGTGATGCCGGGCAATATTATGACCCC
AGGTCTGAAGGCGCTCGGTGATGATTACCTCGCCGAGATGGCGAAGTCTGTGCCGCTGGGGATGCTGGGCGAGGCGAAGG
ACATCGGTGAGGCAGTGGCGTATCTCGCCTCGGATGGGGCGCGCTATGTGACCGGTCAGTCGATCGTGGTGGATGGCGGA
CAGGTCCTGCCTGAGGGGCCGGAGGCGCTTGCGGAAATGTAA

Upstream 100 bases:

>100_bases
TGGCCTGAATCCGGTCGGGGACACCGATTCGCGGTGTTTCCGCTCCAGTTTGTTACCATGAATTGTGTCTCCTGCGATCA
ACGGTGTTGGAGGAGTGACA

Downstream 100 bases:

>100_bases
GTTAGTTTTCCTCCGCGCCGAGGCTGATTGCATCTGGCACGAACTGGGCGCGTCAGGAGGCCCGCCGTAATACCCGGAGA
ATCGGGCCTCCTAACAATGC

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTGLLAGRTALVTGGTAGIGRGIAEVLALHGARVAVTGVTEERCAQAREDGLDVYQLDVRDKKACIRVVNDVAAECGGLS
VLVANAGVYPQVRLADLDDDQIDFIFDVNVKGMMHVVQAATPALRESGRGRIVVTSSITGNITGYPGWSHYGATKAAQMG
FIRSAAMELAGDKITINAVMPGNIMTPGLKALGDDYLAEMAKSVPLGMLGEAKDIGEAVAYLASDGARYVTGQSIVVDGG
QVLPEGPEALAEM

Sequences:

>Translated_253_residues
MTGLLAGRTALVTGGTAGIGRGIAEVLALHGARVAVTGVTEERCAQAREDGLDVYQLDVRDKKACIRVVNDVAAECGGLS
VLVANAGVYPQVRLADLDDDQIDFIFDVNVKGMMHVVQAATPALRESGRGRIVVTSSITGNITGYPGWSHYGATKAAQMG
FIRSAAMELAGDKITINAVMPGNIMTPGLKALGDDYLAEMAKSVPLGMLGEAKDIGEAVAYLASDGARYVTGQSIVVDGG
QVLPEGPEALAEM
>Mature_252_residues
TGLLAGRTALVTGGTAGIGRGIAEVLALHGARVAVTGVTEERCAQAREDGLDVYQLDVRDKKACIRVVNDVAAECGGLSV
LVANAGVYPQVRLADLDDDQIDFIFDVNVKGMMHVVQAATPALRESGRGRIVVTSSITGNITGYPGWSHYGATKAAQMGF
IRSAAMELAGDKITINAVMPGNIMTPGLKALGDDYLAEMAKSVPLGMLGEAKDIGEAVAYLASDGARYVTGQSIVVDGGQ
VLPEGPEALAEM

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=33.8709677419355, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=34.8, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=34.9593495934959, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=30.6451612903226, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI40254992, Length=232, Percent_Identity=32.7586206896552, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=31.9672131147541, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=26.171875, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI40807363, Length=192, Percent_Identity=32.2916666666667, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI10190704, Length=270, Percent_Identity=29.2592592592593, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=27.710843373494, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=35.6020942408377, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI210032110, Length=172, Percent_Identity=31.3953488372093, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=32.4324324324324, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI310128830, Length=185, Percent_Identity=30.8108108108108, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI310115468, Length=185, Percent_Identity=30.8108108108108, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI142976729, Length=237, Percent_Identity=29.1139240506329, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI59889578, Length=222, Percent_Identity=29.2792792792793, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4504505, Length=216, Percent_Identity=31.0185185185185, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=36.4341085271318, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=39.0946502057613, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=33.6065573770492, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789378, Length=259, Percent_Identity=30.8880308880309, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=27.5303643724696, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=32.0833333333333, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=31.1475409836066, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=29.0983606557377, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786812, Length=249, Percent_Identity=31.7269076305221, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=27.8225806451613, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787820, Length=223, Percent_Identity=29.5964125560538, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=27.6679841897233, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=26.8482490272374, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=27.4900398406374, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=37.6518218623482, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=34.9794238683128, Blast_Score=124, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=30.9701492537313, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=30.9090909090909, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=32.5490196078431, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562908, Length=279, Percent_Identity=31.1827956989247, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=31.7460317460317, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=30.5970149253731, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=30.4029304029304, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=28.7878787878788, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=29.8507462686567, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=28.996282527881, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=27.3408239700375, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=28.7313432835821, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=29.6577946768061, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=29.5880149812734, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=26.9961977186312, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=28.3400809716599, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17538182, Length=251, Percent_Identity=30.6772908366534, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=27.4193548387097, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=273, Percent_Identity=27.4725274725275, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=27.8195488721804, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=26.5151515151515, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=28.3524904214559, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=28.1124497991968, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=30.0518134715026, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=28.3464566929134, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=254, Percent_Identity=29.5275590551181, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=30.2788844621514, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=26.7676767676768, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=173, Percent_Identity=29.4797687861272, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=181, Percent_Identity=26.5193370165746, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=175, Percent_Identity=25.1428571428571, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=31.7269076305221, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322227, Length=192, Percent_Identity=31.25, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=260, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=221, Percent_Identity=27.1493212669683, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=34.6774193548387, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=32.5301204819277, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=31.0756972111554, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=32.1285140562249, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=31.5789473684211, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=31.5789473684211, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=33.469387755102, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=34.5029239766082, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI18859837, Length=233, Percent_Identity=29.1845493562232, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355631, Length=172, Percent_Identity=29.6511627906977, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581726, Length=192, Percent_Identity=29.6875, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281364892, Length=192, Percent_Identity=29.6875, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357673, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553409, Length=199, Percent_Identity=25.1256281407035, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647948, Length=199, Percent_Identity=25.1256281407035, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647946, Length=199, Percent_Identity=25.1256281407035, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 26205; Mature: 26074

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLLAGRTALVTGGTAGIGRGIAEVLALHGARVAVTGVTEERCAQAREDGLDVYQLDVR
CCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEECCC
DKKACIRVVNDVAAECGGLSVLVANAGVYPQVRLADLDDDQIDFIFDVNVKGMMHVVQAA
CHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHHH
TPALRESGRGRIVVTSSITGNITGYPGWSHYGATKAAQMGFIRSAAMELAGDKITINAVM
CHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEE
PGNIMTPGLKALGDDYLAEMAKSVPLGMLGEAKDIGEAVAYLASDGARYVTGQSIVVDGG
CCCCCCCCHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCEEEEECC
QVLPEGPEALAEM
EECCCCHHHHHCC
>Mature Secondary Structure 
TGLLAGRTALVTGGTAGIGRGIAEVLALHGARVAVTGVTEERCAQAREDGLDVYQLDVR
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEECCC
DKKACIRVVNDVAAECGGLSVLVANAGVYPQVRLADLDDDQIDFIFDVNVKGMMHVVQAA
CHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHHH
TPALRESGRGRIVVTSSITGNITGYPGWSHYGATKAAQMGFIRSAAMELAGDKITINAVM
CHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEE
PGNIMTPGLKALGDDYLAEMAKSVPLGMLGEAKDIGEAVAYLASDGARYVTGQSIVVDGG
CCCCCCCCHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCEEEEECC
QVLPEGPEALAEM
EECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]