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The map label for this gene is exoX [H]

Identifier: 50843187

GI number: 50843187

Start: 1882586

End: 1883296

Strand: Direct

Name: exoX [H]

Synonym: PPA1727

Alternate gene names: 50843187

Gene position: 1882586-1883296 (Clockwise)

Preceding gene: 50843186

Following gene: 50843199

Centisome position: 73.53

GC content: 61.18

Gene sequence:

>711_bases
GTGTCGCAGGTGGGAACTATTCTGACGCCAGTCGCTTTCCGAGGACAGGAAAACAAGAGGGGTAAAGCGGAGGTACACAT
GGCGTTGCAGAAATGGCCCAACCGAGGCGCGAGCAACGCCACACCGGCAGGCTTCATGTCGACCCGGAGGACTCAGCGTC
GGTCCTTCTTCATCCCCTCCCCCTCGCAGATCGCCGAGCCGAGTTTCGTCGCGGTGGACTTCGAGACAGCCAACCGAATG
GGCGGAGTATCGGCCTGCCAGGTGGCCATGGTGAAGGTGTGTGACGGACAGATCGTCGACAGGTTGAACACCTTAATCCG
TCCGCCCAAGGGGTGGGACTCCTTTGAGTTCACCTATCTGCATGGCATCTCTGCAGCCGACGTCGCGGACGCCCCCAGCT
GGACCAACATTGCCGACACCGTTTCCCACTTTGTGGATGGGGTGACCGTATACGCCCATAACGCCGCTTTCGACTCCCGG
GTGTGGCGACAGCTTGACGAGCACTTCGGCACCACCACCCTGCCCGCACCGTTCTTTTGCTCGTATCGGACAGCGCAGCG
CCTCATCCCGGGGTTACCCAACTACAAGCTCCCCACGGTGCTTCACGCTTGTGCCCCGAATTACCAGCTCAACCATCATC
GAGCCGACTCCGACGCCGAAGCCTGCGCCCTCATCGTCTGCGAGTTACAGAGACGGGCGCAGGCAAGCTGA

Upstream 100 bases:

>100_bases
TCGAGCTGCTGGCGTTGCCAACACACTGCCTCAATTGACAGCACCACTGCCCGACGTCACGTCAACCAAACCCTACCGAC
GCCGCTGTAGGGGATCGCCA

Downstream 100 bases:

>100_bases
CTCACTGCGGGTTGACCGGGGCCCATTGCGGACCGGTTTGGGCGAGCTTAGCGTCGAGCTTCCGGAAGATGGGCGAAGGT
TTAGACAGCGGAGTACCTAC

Product: putative DNA polymerase III epsilon subunit (exonuclease)

Products: NA

Alternate protein names: Exodeoxyribonuclease X; Exo X; Exonuclease X [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSQVGTILTPVAFRGQENKRGKAEVHMALQKWPNRGASNATPAGFMSTRRTQRRSFFIPSPSQIAEPSFVAVDFETANRM
GGVSACQVAMVKVCDGQIVDRLNTLIRPPKGWDSFEFTYLHGISAADVADAPSWTNIADTVSHFVDGVTVYAHNAAFDSR
VWRQLDEHFGTTTLPAPFFCSYRTAQRLIPGLPNYKLPTVLHACAPNYQLNHHRADSDAEACALIVCELQRRAQAS

Sequences:

>Translated_236_residues
MSQVGTILTPVAFRGQENKRGKAEVHMALQKWPNRGASNATPAGFMSTRRTQRRSFFIPSPSQIAEPSFVAVDFETANRM
GGVSACQVAMVKVCDGQIVDRLNTLIRPPKGWDSFEFTYLHGISAADVADAPSWTNIADTVSHFVDGVTVYAHNAAFDSR
VWRQLDEHFGTTTLPAPFFCSYRTAQRLIPGLPNYKLPTVLHACAPNYQLNHHRADSDAEACALIVCELQRRAQAS
>Mature_235_residues
SQVGTILTPVAFRGQENKRGKAEVHMALQKWPNRGASNATPAGFMSTRRTQRRSFFIPSPSQIAEPSFVAVDFETANRMG
GVSACQVAMVKVCDGQIVDRLNTLIRPPKGWDSFEFTYLHGISAADVADAPSWTNIADTVSHFVDGVTVYAHNAAFDSRV
WRQLDEHFGTTTLPAPFFCSYRTAQRLIPGLPNYKLPTVLHACAPNYQLNHHRADSDAEACALIVCELQRRAQAS

Specific function: Capable of degrading both single-strand and double- strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA. May facilitate recombinational repair by pre- synaptic and/or post-synaptic DNA degradation [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788149, Length=163, Percent_Identity=31.9018404907975, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 26039; Mature: 25907

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVGTILTPVAFRGQENKRGKAEVHMALQKWPNRGASNATPAGFMSTRRTQRRSFFIPS
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCEEECCC
PSQIAEPSFVAVDFETANRMGGVSACQVAMVKVCDGQIVDRLNTLIRPPKGWDSFEFTYL
CHHHCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEEEE
HGISAADVADAPSWTNIADTVSHFVDGVTVYAHNAAFDSRVWRQLDEHFGTTTLPAPFFC
ECCCHHCCCCCCCCCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHH
SYRTAQRLIPGLPNYKLPTVLHACAPNYQLNHHRADSDAEACALIVCELQRRAQAS
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQVGTILTPVAFRGQENKRGKAEVHMALQKWPNRGASNATPAGFMSTRRTQRRSFFIPS
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCEEECCC
PSQIAEPSFVAVDFETANRMGGVSACQVAMVKVCDGQIVDRLNTLIRPPKGWDSFEFTYL
CHHHCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEEEE
HGISAADVADAPSWTNIADTVSHFVDGVTVYAHNAAFDSRVWRQLDEHFGTTTLPAPFFC
ECCCHHCCCCCCCCCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHH
SYRTAQRLIPGLPNYKLPTVLHACAPNYQLNHHRADSDAEACALIVCELQRRAQAS
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]