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The map label for this gene is malF [H]

Identifier: 50843028

GI number: 50843028

Start: 1670910

End: 1672514

Strand: Direct

Name: malF [H]

Synonym: PPA1553

Alternate gene names: 50843028

Gene position: 1670910-1672514 (Clockwise)

Preceding gene: 50843027

Following gene: 50843029

Centisome position: 65.26

GC content: 56.45

Gene sequence:

>1605_bases
ATGTCGTCATCGTTAACCATCAACCGCAAGACCCGAGAAAAACGTGTCGCCGCAGCGAGCGGCAAGTACTCCGGGTCGCT
GTGGGCCTGGATCACCAAGATCGCCTTGCTCGGCATCCTCGACGCCATCGCCGTCTACGGCGTTATGACCGCCATTGCTC
ACAGTTCACCCCTGATGGCCATCGTCATCGCTGCTGTCGCCATCATCGTCACCGTCATATACGTGCCACCCAACCGGATG
TTGCCCGCCAAGTATCTGGCACCGGGCATCATCTTCATGGTTTTCTTCTCGGTAGGCGTGATGGCCTATACGATCTATGT
GGGTTTCACGAATTATGGCGACGGCCACAACGGCAGCCGTGACGACGCCGTCGCCGCCATCCAACGCAACCACCAGGAAC
GCGTCCCCAACGCTCCGGCCTACAACTCGAGCGTCGCCGAAAAGGACGGCAAGCTGGCCCTGATCGTCATTGACCCCGAC
ACCAAAAAGGTACAAGCTGGCACCCCCGACCAGCCTCTAGAACCGGTCAAGGGAGCTGAACTCAACTCTTTAGGCAAGAT
CAAGAATCTTCCGGGTTACCGCGTCCTCGCTTTCTCCGAGGTGTCCCAACGCAGTGACGAGATCTCCCAGTTGCAGGTTC
CCGTCTCCAAGAACTCTTCGGCCAGATTCATCCGCACCACCACCGGCTCGCAAGCCTTCGAATTCATCTCGACGATAACC
TACGACAAGAATGCCGGGACGATGACCGATAAAAAGGGCACCGTCTACAGAGAAAATGGGCGTGGCAATTTCGTTTCAGT
TTCTGGTAAAGCGCTAGAGCCAGACTGGAAAGTTACCGTCGGGTTCTCTAACTTCAAGAAAGCTCTCACCGACCATGACG
TACGTAGGCCATTCCTGCGAGTAACAGCGTGGACGTTCGCCTTCGCGGTGCTGTCGGTACTCACCACCTTCGCCCTCGGT
CTCGCCCTGGCCCTGTTATTCAATGACGCATCTATGAAGGGGCAGCAGACTTACCGGATACTCATGCTGCTTCCCTACGC
CTTCCCGGGCTTCTTGTCGGCCCTGGTGTGGTCAGGCATGTTCAACCAAGAGTTCGGCCTTATCAACCAAGTATTGTTAG
GCGCAGTATCGATCCCATGGCTGACTAATCCTTGGATTGCTAAGGCAGCCGTTCTTATCGTCAACGTGTGGCTGGGCTTC
CCCTACATGTTCATCATCTCGACGGGCGCCCTGCAGTCCATCCCGTCCGACATTCTGGAGGCCTCTCGGATCGACGGCGC
AAGCACCTGGCGAACCTTTACCAAGATCAAGCTTCCACTGCTCATGGTGCCACTGGCCCCGCTGCTCATCAGCTCTTTCG
CCTTCAACTTCAATAACTTTGTCCTCATCTACATGCTGACCCTCGGTGGCCCCCGGTTCACCGACACCAGCCTCGACGTC
GGCGCTACCGACATCCTTATCTCGATGGTGTACAAGGTTGCCTTCTCTGGAGCTCAACGCGACTATGGCCTGGCGAGCGC
TTTCTCTGTCATTATCTTCATCATTGTTGGCGTGATCTCCTGGCTCGGGTTCCGCCAGACCAAAACCCTTGAGGAGGTCA
ACTGA

Upstream 100 bases:

>100_bases
TCGCAGCTATCTGGTGGGGCATACCGCATAGTATGCCCCACCCTCGCAACGCCAATGACGGCGTTTCCTATGACCCGTGA
AATCGGAGAATCCCCACATC

Downstream 100 bases:

>100_bases
TGAGCACCGCAACAGTGGCTTCTGCAATCAAAGATGCCAACCGCAACACCCCGTTTTCCAAGCAGTTCAAGTCACAGTGG
TGGCGTCACCTCCTTGGCAT

Product: maltose transport system permease protein MalF

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MSSSLTINRKTREKRVAAASGKYSGSLWAWITKIALLGILDAIAVYGVMTAIAHSSPLMAIVIAAVAIIVTVIYVPPNRM
LPAKYLAPGIIFMVFFSVGVMAYTIYVGFTNYGDGHNGSRDDAVAAIQRNHQERVPNAPAYNSSVAEKDGKLALIVIDPD
TKKVQAGTPDQPLEPVKGAELNSLGKIKNLPGYRVLAFSEVSQRSDEISQLQVPVSKNSSARFIRTTTGSQAFEFISTIT
YDKNAGTMTDKKGTVYRENGRGNFVSVSGKALEPDWKVTVGFSNFKKALTDHDVRRPFLRVTAWTFAFAVLSVLTTFALG
LALALLFNDASMKGQQTYRILMLLPYAFPGFLSALVWSGMFNQEFGLINQVLLGAVSIPWLTNPWIAKAAVLIVNVWLGF
PYMFIISTGALQSIPSDILEASRIDGASTWRTFTKIKLPLLMVPLAPLLISSFAFNFNNFVLIYMLTLGGPRFTDTSLDV
GATDILISMVYKVAFSGAQRDYGLASAFSVIIFIIVGVISWLGFRQTKTLEEVN

Sequences:

>Translated_534_residues
MSSSLTINRKTREKRVAAASGKYSGSLWAWITKIALLGILDAIAVYGVMTAIAHSSPLMAIVIAAVAIIVTVIYVPPNRM
LPAKYLAPGIIFMVFFSVGVMAYTIYVGFTNYGDGHNGSRDDAVAAIQRNHQERVPNAPAYNSSVAEKDGKLALIVIDPD
TKKVQAGTPDQPLEPVKGAELNSLGKIKNLPGYRVLAFSEVSQRSDEISQLQVPVSKNSSARFIRTTTGSQAFEFISTIT
YDKNAGTMTDKKGTVYRENGRGNFVSVSGKALEPDWKVTVGFSNFKKALTDHDVRRPFLRVTAWTFAFAVLSVLTTFALG
LALALLFNDASMKGQQTYRILMLLPYAFPGFLSALVWSGMFNQEFGLINQVLLGAVSIPWLTNPWIAKAAVLIVNVWLGF
PYMFIISTGALQSIPSDILEASRIDGASTWRTFTKIKLPLLMVPLAPLLISSFAFNFNNFVLIYMLTLGGPRFTDTSLDV
GATDILISMVYKVAFSGAQRDYGLASAFSVIIFIIVGVISWLGFRQTKTLEEVN
>Mature_533_residues
SSSLTINRKTREKRVAAASGKYSGSLWAWITKIALLGILDAIAVYGVMTAIAHSSPLMAIVIAAVAIIVTVIYVPPNRML
PAKYLAPGIIFMVFFSVGVMAYTIYVGFTNYGDGHNGSRDDAVAAIQRNHQERVPNAPAYNSSVAEKDGKLALIVIDPDT
KKVQAGTPDQPLEPVKGAELNSLGKIKNLPGYRVLAFSEVSQRSDEISQLQVPVSKNSSARFIRTTTGSQAFEFISTITY
DKNAGTMTDKKGTVYRENGRGNFVSVSGKALEPDWKVTVGFSNFKKALTDHDVRRPFLRVTAWTFAFAVLSVLTTFALGL
ALALLFNDASMKGQQTYRILMLLPYAFPGFLSALVWSGMFNQEFGLINQVLLGAVSIPWLTNPWIAKAAVLIVNVWLGFP
YMFIISTGALQSIPSDILEASRIDGASTWRTFTKIKLPLLMVPLAPLLISSFAFNFNNFVLIYMLTLGGPRFTDTSLDVG
ATDILISMVYKVAFSGAQRDYGLASAFSVIIFIIVGVISWLGFRQTKTLEEVN

Specific function: Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790465, Length=473, Percent_Identity=34.46088794926, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1787570, Length=251, Percent_Identity=31.8725099601594, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789861, Length=218, Percent_Identity=34.4036697247706, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 58317; Mature: 58185

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSLTINRKTREKRVAAASGKYSGSLWAWITKIALLGILDAIAVYGVMTAIAHSSPLMA
CCCCEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IVIAAVAIIVTVIYVPPNRMLPAKYLAPGIIFMVFFSVGVMAYTIYVGFTNYGDGHNGSR
HHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
DDAVAAIQRNHQERVPNAPAYNSSVAEKDGKLALIVIDPDTKKVQAGTPDQPLEPVKGAE
HHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCC
LNSLGKIKNLPGYRVLAFSEVSQRSDEISQLQVPVSKNSSARFIRTTTGSQAFEFISTIT
CCCCCCCCCCCCCEEEEEHHHHHHHHHHHHEECCCCCCCCCEEEEECCCHHHHHHHHHHE
YDKNAGTMTDKKGTVYRENGRGNFVSVSGKALEPDWKVTVGFSNFKKALTDHDVRRPFLR
ECCCCCCCCCCCCCEEEECCCCCEEEECCCEECCCCEEEECHHHHHHHHHHHHHHHHHHH
VTAWTFAFAVLSVLTTFALGLALALLFNDASMKGQQTYRILMLLPYAFPGFLSALVWSGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEHHHHHHHHHHHHHHCCC
FNQEFGLINQVLLGAVSIPWLTNPWIAKAAVLIVNVWLGFPYMFIISTGALQSIPSDILE
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCHHHHH
ASRIDGASTWRTFTKIKLPLLMVPLAPLLISSFAFNFNNFVLIYMLTLGGPRFTDTSLDV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCC
GATDILISMVYKVAFSGAQRDYGLASAFSVIIFIIVGVISWLGFRQTKTLEEVN
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCHHHHCC
>Mature Secondary Structure 
SSSLTINRKTREKRVAAASGKYSGSLWAWITKIALLGILDAIAVYGVMTAIAHSSPLMA
CCCEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IVIAAVAIIVTVIYVPPNRMLPAKYLAPGIIFMVFFSVGVMAYTIYVGFTNYGDGHNGSR
HHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
DDAVAAIQRNHQERVPNAPAYNSSVAEKDGKLALIVIDPDTKKVQAGTPDQPLEPVKGAE
HHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCC
LNSLGKIKNLPGYRVLAFSEVSQRSDEISQLQVPVSKNSSARFIRTTTGSQAFEFISTIT
CCCCCCCCCCCCCEEEEEHHHHHHHHHHHHEECCCCCCCCCEEEEECCCHHHHHHHHHHE
YDKNAGTMTDKKGTVYRENGRGNFVSVSGKALEPDWKVTVGFSNFKKALTDHDVRRPFLR
ECCCCCCCCCCCCCEEEECCCCCEEEECCCEECCCCEEEECHHHHHHHHHHHHHHHHHHH
VTAWTFAFAVLSVLTTFALGLALALLFNDASMKGQQTYRILMLLPYAFPGFLSALVWSGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEHHHHHHHHHHHHHHCCC
FNQEFGLINQVLLGAVSIPWLTNPWIAKAAVLIVNVWLGFPYMFIISTGALQSIPSDILE
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCHHHHH
ASRIDGASTWRTFTKIKLPLLMVPLAPLLISSFAFNFNNFVLIYMLTLGGPRFTDTSLDV
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCC
GATDILISMVYKVAFSGAQRDYGLASAFSVIIFIIVGVISWLGFRQTKTLEEVN
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA