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The map label for this gene is xerC

Identifier: 50843000

GI number: 50843000

Start: 1644242

End: 1645189

Strand: Direct

Name: xerC

Synonym: PPA1522

Alternate gene names: 50843000

Gene position: 1644242-1645189 (Clockwise)

Preceding gene: 50842990

Following gene: 50843002

Centisome position: 64.22

GC content: 63.4

Gene sequence:

>948_bases
ATGAAGAAGCCATCCCCGACGCGCGTTGGCGCCGGACAGCTGCCTATGTCCCTGACGGTGCCCGTCGAGGACTTCTGTGG
CCACCTCTCGGCTCTCCGACGCTCGCCCAACACAATCCGCGGTTACCGAGCTGACCTCATCGATCTCATGGGCCACGCTC
ACTCCCACGGCGACGACACCTTGGGCAGGATCGGCACATCGCAAGTGCGAGCATGGCTAGCTGATACCCGTGTGGCTGGC
GCCTCGGCCGCTACCATGCAGCGCCGCTGGTCGGCTGCGCGAGTATTTTTCCGCTGGGCGGCTAACGAAGGGCTCATTTC
CGCCGATCCGACGACCGCTCTGAATTCGGCCAAAGTACCGAAACGCCTGCCGGCCACTCTGGGCGTCGATCAGGCTCGTC
ACATCCTCGACGAAGCCGTAGCACAGGCTCGTCACGATGAATCTCCCCACGGCGCACGCGACGCCGCCATCCTTGAGGTC
CTTTACGGTGGAGGGCTGCGTGTCGGCGAGCTGTGCGGTCTTGATCTGGGTGACGTCGATCGATCTCGCCGCACTGTGAA
AGTTACGGGCAAGGGCGACAAAGAACGCACCGTGCCTATGGGGGCGCCTGCGCTGCGTGCCATCGATACGTGGTTACCTC
GTCGTGAGGAATGGGTTGGGCCGCACTCCGGGCAGGCCCTCTTTTTGGGAGCGCGTGGTCGTCGCATCGATCAGCGCGTC
GTTCGGCGAGTCGTTCACACCGACTTGCGTGCCGAACCAGACTCCCCCGACCTTGGGCCTCACGGGTTACGTCACGCGAT
GGCGACCCATCTTTTGGAAGGCGGAGCAGATCTGCGCACCGTCCAGGACATATTGGGCCACGAATCCCTAGCCACCACGC
AGATCTACACCCACGTTTCCACCGAAAGATTGCGCACTGCGTTTCGCCAGGCTCATCCCCGCGCCTGA

Upstream 100 bases:

>100_bases
TTACGACACCAAGAGGCAATCAAGCTAACCTTCCCCTTGACCCCGGCCACTTCCGCGTGTCTGCCTACCATGGCGGCAAT
CACAGGCCACAGTGGATGTG

Downstream 100 bases:

>100_bases
GCCACCTCGGGTGGCTTCGGTCACCGTCGTATCAATGCCTAACGCGGCGTCCCGCCCAGCTCCACGCCACGGAGGCATGA
GGGCACCGCTTGAGGCAGCT

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKKPSPTRVGAGQLPMSLTVPVEDFCGHLSALRRSPNTIRGYRADLIDLMGHAHSHGDDTLGRIGTSQVRAWLADTRVAG
ASAATMQRRWSAARVFFRWAANEGLISADPTTALNSAKVPKRLPATLGVDQARHILDEAVAQARHDESPHGARDAAILEV
LYGGGLRVGELCGLDLGDVDRSRRTVKVTGKGDKERTVPMGAPALRAIDTWLPRREEWVGPHSGQALFLGARGRRIDQRV
VRRVVHTDLRAEPDSPDLGPHGLRHAMATHLLEGGADLRTVQDILGHESLATTQIYTHVSTERLRTAFRQAHPRA

Sequences:

>Translated_315_residues
MKKPSPTRVGAGQLPMSLTVPVEDFCGHLSALRRSPNTIRGYRADLIDLMGHAHSHGDDTLGRIGTSQVRAWLADTRVAG
ASAATMQRRWSAARVFFRWAANEGLISADPTTALNSAKVPKRLPATLGVDQARHILDEAVAQARHDESPHGARDAAILEV
LYGGGLRVGELCGLDLGDVDRSRRTVKVTGKGDKERTVPMGAPALRAIDTWLPRREEWVGPHSGQALFLGARGRRIDQRV
VRRVVHTDLRAEPDSPDLGPHGLRHAMATHLLEGGADLRTVQDILGHESLATTQIYTHVSTERLRTAFRQAHPRA
>Mature_315_residues
MKKPSPTRVGAGQLPMSLTVPVEDFCGHLSALRRSPNTIRGYRADLIDLMGHAHSHGDDTLGRIGTSQVRAWLADTRVAG
ASAATMQRRWSAARVFFRWAANEGLISADPTTALNSAKVPKRLPATLGVDQARHILDEAVAQARHDESPHGARDAAILEV
LYGGGLRVGELCGLDLGDVDRSRRTVKVTGKGDKERTVPMGAPALRAIDTWLPRREEWVGPHSGQALFLGARGRRIDQRV
VRRVVHTDLRAEPDSPDLGPHGLRHAMATHLLEGGADLRTVQDILGHESLATTQIYTHVSTERLRTAFRQAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=283, Percent_Identity=42.0494699646643, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1790244, Length=299, Percent_Identity=36.7892976588629, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1790768, Length=155, Percent_Identity=30.3225806451613, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790767, Length=154, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34350; Mature: 34350

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPSPTRVGAGQLPMSLTVPVEDFCGHLSALRRSPNTIRGYRADLIDLMGHAHSHGDDT
CCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHH
LGRIGTSQVRAWLADTRVAGASAATMQRRWSAARVFFRWAANEGLISADPTTALNSAKVP
HHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCC
KRLPATLGVDQARHILDEAVAQARHDESPHGARDAAILEVLYGGGLRVGELCGLDLGDVD
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCC
RSRRTVKVTGKGDKERTVPMGAPALRAIDTWLPRREEWVGPHSGQALFLGARGRRIDQRV
CCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCCHHHHHH
VRRVVHTDLRAEPDSPDLGPHGLRHAMATHLLEGGADLRTVQDILGHESLATTQIYTHVS
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
TERLRTAFRQAHPRA
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKPSPTRVGAGQLPMSLTVPVEDFCGHLSALRRSPNTIRGYRADLIDLMGHAHSHGDDT
CCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHH
LGRIGTSQVRAWLADTRVAGASAATMQRRWSAARVFFRWAANEGLISADPTTALNSAKVP
HHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCC
KRLPATLGVDQARHILDEAVAQARHDESPHGARDAAILEVLYGGGLRVGELCGLDLGDVD
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCC
RSRRTVKVTGKGDKERTVPMGAPALRAIDTWLPRREEWVGPHSGQALFLGARGRRIDQRV
CCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCCHHHHHH
VRRVVHTDLRAEPDSPDLGPHGLRHAMATHLLEGGADLRTVQDILGHESLATTQIYTHVS
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
TERLRTAFRQAHPRA
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA