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The map label for this gene is frr

Identifier: 50842996

GI number: 50842996

Start: 1640771

End: 1641325

Strand: Reverse

Name: frr

Synonym: PPA1518

Alternate gene names: 50842996

Gene position: 1641325-1640771 (Counterclockwise)

Preceding gene: 50842997

Following gene: 50842995

Centisome position: 64.11

GC content: 56.58

Gene sequence:

>555_bases
GTGAGCGACATCATTAAGGACGCCGAGAAAAAGATGGGGTCAGCGGTCGACCATGCCCGCGAGGAGTTCGCGGCTATTCG
CACCGGGCGTGCTAACCCCGCCATGTTTAACAAACTCATGGTCGAGTACTACGGTACCCCTACCCCGCTGCAGCAGCTCG
CCAGTTTCCAGGTGCCGGAGGCTCGCACTGTCCTTATCGCGCCATTCGATAAGAGTTGTGTCAATGACGTCGAGAAGGCT
ATTCGGGATTCCGACCTAGGAGTCAACCCCTCCAACGATGGCAACGTGGTGCGTTGCGTCCTTCCAGCTCTGACTGAGGA
GCGCCGCAAGGAGTACATCAAGATGGCCAAGACTAAGGCTGAGGAGGGGCGTATCGCGGTCCGCAACGTCCGTCGCGCCA
GCAACGATGTTGTCAAAAAGCAGGAGAAGGACAAGGAGATCTCTGAGGACGAGATGACTCGTCTGGAGAAGGAGCTTGAC
CAGGTCACCCGCAAGTACGTTGAGCAGATTGACGAATTGCTGAAATCCAAGGAGAGCGAACTCCTCGAGATCTGA

Upstream 100 bases:

>100_bases
TCGAGATGCCAGGCAATATTAGCCGCGTCATCAATGGTGAGGACATCGGCACCACCGTCCATCGCTGAACCATCGAGACA
TACCAAGGAAGGACAACACA

Downstream 100 bases:

>100_bases
TCAGATTCGAGGTGGGCGAGCCTGAGAAGAAGACCACGGCCGCACGGACTCCACGTGCCGGCCGTGATCTTCCTGCTGCC
ATCACTACGGGCGTAGTGCT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSDIIKDAEKKMGSAVDHAREEFAAIRTGRANPAMFNKLMVEYYGTPTPLQQLASFQVPEARTVLIAPFDKSCVNDVEKA
IRDSDLGVNPSNDGNVVRCVLPALTEERRKEYIKMAKTKAEEGRIAVRNVRRASNDVVKKQEKDKEISEDEMTRLEKELD
QVTRKYVEQIDELLKSKESELLEI

Sequences:

>Translated_184_residues
MSDIIKDAEKKMGSAVDHAREEFAAIRTGRANPAMFNKLMVEYYGTPTPLQQLASFQVPEARTVLIAPFDKSCVNDVEKA
IRDSDLGVNPSNDGNVVRCVLPALTEERRKEYIKMAKTKAEEGRIAVRNVRRASNDVVKKQEKDKEISEDEMTRLEKELD
QVTRKYVEQIDELLKSKESELLEI
>Mature_183_residues
SDIIKDAEKKMGSAVDHAREEFAAIRTGRANPAMFNKLMVEYYGTPTPLQQLASFQVPEARTVLIAPFDKSCVNDVEKAI
RDSDLGVNPSNDGNVVRCVLPALTEERRKEYIKMAKTKAEEGRIAVRNVRRASNDVVKKQEKDKEISEDEMTRLEKELDQ
VTRKYVEQIDELLKSKESELLEI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=184, Percent_Identity=29.8913043478261, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI291042689, Length=128, Percent_Identity=33.59375, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=48.9130434782609, Blast_Score=174, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=26.5895953757225, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PROAC (Q6A7K0)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056223.1
- ProteinModelPortal:   Q6A7K0
- SMR:   Q6A7K0
- GeneID:   2931040
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1518
- NMPDR:   fig|267747.1.peg.1500
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   CLSK2764021
- BioCyc:   PACN267747:PPA1518-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20930; Mature: 20799

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIIKDAEKKMGSAVDHAREEFAAIRTGRANPAMFNKLMVEYYGTPTPLQQLASFQVPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCC
ARTVLIAPFDKSCVNDVEKAIRDSDLGVNPSNDGNVVRCVLPALTEERRKEYIKMAKTKA
CCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
EEGRIAVRNVRRASNDVVKKQEKDKEISEDEMTRLEKELDQVTRKYVEQIDELLKSKESE
HCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLEI
HHCC
>Mature Secondary Structure 
SDIIKDAEKKMGSAVDHAREEFAAIRTGRANPAMFNKLMVEYYGTPTPLQQLASFQVPE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCC
ARTVLIAPFDKSCVNDVEKAIRDSDLGVNPSNDGNVVRCVLPALTEERRKEYIKMAKTKA
CCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
EEGRIAVRNVRRASNDVVKKQEKDKEISEDEMTRLEKELDQVTRKYVEQIDELLKSKESE
HCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLEI
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA