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The map label for this gene is cdsA [H]

Identifier: 50842995

GI number: 50842995

Start: 1639896

End: 1640759

Strand: Reverse

Name: cdsA [H]

Synonym: PPA1517

Alternate gene names: 50842995

Gene position: 1640759-1639896 (Counterclockwise)

Preceding gene: 50842996

Following gene: 50842994

Centisome position: 64.09

GC content: 59.61

Gene sequence:

>864_bases
GTGGGCGAGCCTGAGAAGAAGACCACGGCCGCACGGACTCCACGTGCCGGCCGTGATCTTCCTGCTGCCATCACTACGGG
CGTAGTGCTGTGCGGTGCCGTCATCGGCACCGTTGGATGGTGGCATTGGGGTTTCGTGTTGTTGATGACCTTGGCCCTTA
TGGCCGGGGCCATTGAGCTTCATCGAGCGATGGTTCGTTTGGGAATGGACTCCGCGGTAGTTCCGATATGCGTCGGCACC
GCAGTTATGGTCATTGGGGCATATGCGGCCTCGACCCTGAAGCTTCACATCCTGCCCAATACCTTCCTGGTGGTGACGTT
AGGTGCGACGACAGTTGCCGCAATGGCGTGGCGACTGCCACGCGGGTCGCATGGCTTCGTCAAGGACGCTGCTGCCAGCC
TTTTCACTATCGCCTACTTGCCATTGCTTGGCTGCTTCGTTCCCCTCATGATGGGCGATGACGGTGGTAGCCGCCGCATC
GCTACCTGGATCCTCAGCGTCGTGGCTTCTGACACCGGCGGTTATGCCGTAGGGGTGCTATGTGGCAAACACAAGTTGGC
CCCGCGTATTAGCCCGAAAAAGAGCTGGGAGGGTTTTGCCGGGTCCGTCATAACCGCAGCTTTCGTTGGATGGGCCTGTT
TGGGAGGATTGCTGTCGGCGCCATGGTGGGCTGGGATTGTTCTTGGCGTTGTTCTAGCCTTGACCGGCACTGCGGGAGAC
CTTGTCGAGTCGATGATTAAGCGTGACGCTGGTATCAAGGACATGTCGAACTTCTTGCCCGGTCATGGCGGGGTCATGGA
CCGGCTCGACTCAGTGCTGTTTTCGGCGCCCTTCGCCTGGCTCGTCATGTCCCTTGTGCTGTGA

Upstream 100 bases:

>100_bases
AGAAGGAGCTTGACCAGGTCACCCGCAAGTACGTTGAGCAGATTGACGAATTGCTGAAATCCAAGGAGAGCGAACTCCTC
GAGATCTGATCAGATTCGAG

Downstream 100 bases:

>100_bases
CTGTAGTCGCGGGGCCACTCCACTATGAGCTTGGCCAAGCTCCGATGATATACTATCTCCTAAGTAATAGCTATTAGGTA
TAGATGGGGGCGAAGATGGA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MGEPEKKTTAARTPRAGRDLPAAITTGVVLCGAVIGTVGWWHWGFVLLMTLALMAGAIELHRAMVRLGMDSAVVPICVGT
AVMVIGAYAASTLKLHILPNTFLVVTLGATTVAAMAWRLPRGSHGFVKDAAASLFTIAYLPLLGCFVPLMMGDDGGSRRI
ATWILSVVASDTGGYAVGVLCGKHKLAPRISPKKSWEGFAGSVITAAFVGWACLGGLLSAPWWAGIVLGVVLALTGTAGD
LVESMIKRDAGIKDMSNFLPGHGGVMDRLDSVLFSAPFAWLVMSLVL

Sequences:

>Translated_287_residues
MGEPEKKTTAARTPRAGRDLPAAITTGVVLCGAVIGTVGWWHWGFVLLMTLALMAGAIELHRAMVRLGMDSAVVPICVGT
AVMVIGAYAASTLKLHILPNTFLVVTLGATTVAAMAWRLPRGSHGFVKDAAASLFTIAYLPLLGCFVPLMMGDDGGSRRI
ATWILSVVASDTGGYAVGVLCGKHKLAPRISPKKSWEGFAGSVITAAFVGWACLGGLLSAPWWAGIVLGVVLALTGTAGD
LVESMIKRDAGIKDMSNFLPGHGGVMDRLDSVLFSAPFAWLVMSLVL
>Mature_286_residues
GEPEKKTTAARTPRAGRDLPAAITTGVVLCGAVIGTVGWWHWGFVLLMTLALMAGAIELHRAMVRLGMDSAVVPICVGTA
VMVIGAYAASTLKLHILPNTFLVVTLGATTVAAMAWRLPRGSHGFVKDAAASLFTIAYLPLLGCFVPLMMGDDGGSRRIA
TWILSVVASDTGGYAVGVLCGKHKLAPRISPKKSWEGFAGSVITAAFVGWACLGGLLSAPWWAGIVLGVVLALTGTAGDL
VESMIKRDAGIKDMSNFLPGHGGVMDRLDSVLFSAPFAWLVMSLVL

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=130, Percent_Identity=43.8461538461538, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1787677, Length=110, Percent_Identity=40.9090909090909, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29975; Mature: 29844

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEPEKKTTAARTPRAGRDLPAAITTGVVLCGAVIGTVGWWHWGFVLLMTLALMAGAIEL
CCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRAMVRLGMDSAVVPICVGTAVMVIGAYAASTLKLHILPNTFLVVTLGATTVAAMAWRLP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEECHHHHHHHHHHCC
RGSHGFVKDAAASLFTIAYLPLLGCFVPLMMGDDGGSRRIATWILSVVASDTGGYAVGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
CGKHKLAPRISPKKSWEGFAGSVITAAFVGWACLGGLLSAPWWAGIVLGVVLALTGTAGD
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHH
LVESMIKRDAGIKDMSNFLPGHGGVMDRLDSVLFSAPFAWLVMSLVL
HHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHC
>Mature Secondary Structure 
GEPEKKTTAARTPRAGRDLPAAITTGVVLCGAVIGTVGWWHWGFVLLMTLALMAGAIEL
CCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRAMVRLGMDSAVVPICVGTAVMVIGAYAASTLKLHILPNTFLVVTLGATTVAAMAWRLP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEECHHHHHHHHHHCC
RGSHGFVKDAAASLFTIAYLPLLGCFVPLMMGDDGGSRRIATWILSVVASDTGGYAVGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
CGKHKLAPRISPKKSWEGFAGSVITAAFVGWACLGGLLSAPWWAGIVLGVVLALTGTAGD
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHH
LVESMIKRDAGIKDMSNFLPGHGGVMDRLDSVLFSAPFAWLVMSLVL
HHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]