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The map label for this gene is hisE

Identifier: 50842899

GI number: 50842899

Start: 1538480

End: 1538746

Strand: Reverse

Name: hisE

Synonym: PPA1418

Alternate gene names: 50842899

Gene position: 1538746-1538480 (Counterclockwise)

Preceding gene: 50842900

Following gene: 50842898

Centisome position: 60.1

GC content: 54.31

Gene sequence:

>267_bases
GTGAGCAAGACATTCGAGGAACTTTTCGCCGAGCTGGCAATAAAGTCACAGACCCGTCCTGCAGGTTCGGGAACCGTCGA
GGAGCTTGACCGCGGAGTACATGCCATCGGTAAGAAAATCGTGGAGGAAGCCTCCGAAGTGTGGATGGCAGCCGAGCACG
AGGGCAATGAACGGTTGGCTGAGGAGATCTGCCAGGAGATTTATCACCTGCAGGTCATGATGATTAAGCAGGGCTTGTCG
CTCGACGACGTCTATAAGCATCTGTGA

Upstream 100 bases:

>100_bases
CCAACGTGCGGTCACCGACGACCCCTGTCACTGACATAGCAACGGTCCGTCACGTGGGCGCATCTGTGGCGGTGCTAGGA
CAATCGGTAGCCTGGCAACT

Downstream 100 bases:

>100_bases
ATTCCCGGACATTCCCGACCCGTCATCGTCATCCCTGATAATCCCTGAGGAGACTTCATGTCCGACTTGCTTCGCATTGC
TGTGCCGAATAAGGGTGCTC

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH

Number of amino acids: Translated: 88; Mature: 87

Protein sequence:

>88_residues
MSKTFEELFAELAIKSQTRPAGSGTVEELDRGVHAIGKKIVEEASEVWMAAEHEGNERLAEEICQEIYHLQVMMIKQGLS
LDDVYKHL

Sequences:

>Translated_88_residues
MSKTFEELFAELAIKSQTRPAGSGTVEELDRGVHAIGKKIVEEASEVWMAAEHEGNERLAEEICQEIYHLQVMMIKQGLS
LDDVYKHL
>Mature_87_residues
SKTFEELFAELAIKSQTRPAGSGTVEELDRGVHAIGKKIVEEASEVWMAAEHEGNERLAEEICQEIYHLQVMMIKQGLSL
DDVYKHL

Specific function: Unknown

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HIS2_PROAC (Q6A7U7)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056126.1
- ProteinModelPortal:   Q6A7U7
- SMR:   Q6A7U7
- GeneID:   2931090
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1418
- NMPDR:   fig|267747.1.peg.1403
- HOGENOM:   HBG646527
- OMA:   VWMAAEY
- ProtClustDB:   PRK00400
- BioCyc:   PACN267747:PPA1418-MONOMER
- BRENDA:   3.6.1.31
- GO:   GO:0005737
- HAMAP:   MF_01020
- InterPro:   IPR008179
- InterPro:   IPR021130
- TIGRFAMs:   TIGR03188

Pfam domain/function: PF01503 PRA-PH

EC number: =3.6.1.31

Molecular weight: Translated: 9944; Mature: 9813

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTFEELFAELAIKSQTRPAGSGTVEELDRGVHAIGKKIVEEASEVWMAAEHEGNERLA
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EEICQEIYHLQVMMIKQGLSLDDVYKHL
HHHHHHHHHHHHHHHHHCCCHHHHHHCC
>Mature Secondary Structure 
SKTFEELFAELAIKSQTRPAGSGTVEELDRGVHAIGKKIVEEASEVWMAAEHEGNERLA
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EEICQEIYHLQVMMIKQGLSLDDVYKHL
HHHHHHHHHHHHHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA