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The map label for this gene is ycgM [C]

Identifier: 50842850

GI number: 50842850

Start: 1488927

End: 1489727

Strand: Reverse

Name: ycgM [C]

Synonym: PPA1366

Alternate gene names: 50842850

Gene position: 1489727-1488927 (Counterclockwise)

Preceding gene: 50842852

Following gene: 50842849

Centisome position: 58.19

GC content: 58.18

Gene sequence:

>801_bases
ATGCGTATTGCCCGGTTTGTCACCGCTGGTTCCGACCCTGCCTTCGGGATCGTAGAGCTTGCTGCCGATCATGGAGATCA
TCCCGAGACCATCGCCGTTATCACTGGAGACCCAGTGGCGGCACCGGTTCAATACACTGGTGCCCGTCACGACCTTGCCG
ATGTGCGGTTGCTGTCTCCGGTGATTCCGCGATCGAAGATCATTGGGGTTGGTCGTAACTACGCCGATCACGCCAGCGAA
CTGGGCAATGAGGTTCCCCACCAACCGCTTCTATTTGTTAAGCCGAATACCTCGGTTATCGGCCCTGACGAACCCATTGT
GCGACCGACTGCGTCCTCCAACCTGCACTACGAGGGGGAGCTGGCCATCGTTATCGGACGGATCTGTAAGGACGTGCCAG
AGGACAGAGCTCAGGAAGTCATCTTTGGGTTCACCGTTGCCAATGACGTCACTGCCCGCGATCTGCAAGATTCTGACGGT
CACTGGGTTCGCGCCAAGGGGGCTGACACCTTCTGCCCGCTGGGGCCATGGATGGTTACCCACTTCTCCATTGCAGAAGC
GTCTCACCGCCAGATTGTGACTCGACTAGACGGTAGGGAGGTTCAGCACGGTAATACCGACCAGATGGTCCACACCATCC
CCAAGCTCATCTCCTATATCTCTTCGTTCATGACCTTGTTGCCGGGCGATGTCATCCTCACGGGTACCCCCGCTGGGGTC
GGGCCGATGGAGCTCGGACAGCGCGTCGAGGTTGAAATTGAGGGGATCGGGACGCTAACGAACACTGTCGTGGAGGTCTG
A

Upstream 100 bases:

>100_bases
ACGGAATAGGTGCTGGTCATGGCGCAAGTATGACAGGGCTTACCCTTCTTCAGTGCGTGGATGCCCCGGTTATGTCGCGT
TATGTCGTTAGTCTTAACTC

Downstream 100 bases:

>100_bases
TGGCGGCTCGTGTCCTGTCCCGCCATGTGACGGTGACTGACCCCGAGCCACGGGTCGACTACACCCGGGTTCTCGTTGAT
TCGAGTGCTGGCCCGGGTCC

Product: putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MRIARFVTAGSDPAFGIVELAADHGDHPETIAVITGDPVAAPVQYTGARHDLADVRLLSPVIPRSKIIGVGRNYADHASE
LGNEVPHQPLLFVKPNTSVIGPDEPIVRPTASSNLHYEGELAIVIGRICKDVPEDRAQEVIFGFTVANDVTARDLQDSDG
HWVRAKGADTFCPLGPWMVTHFSIAEASHRQIVTRLDGREVQHGNTDQMVHTIPKLISYISSFMTLLPGDVILTGTPAGV
GPMELGQRVEVEIEGIGTLTNTVVEV

Sequences:

>Translated_266_residues
MRIARFVTAGSDPAFGIVELAADHGDHPETIAVITGDPVAAPVQYTGARHDLADVRLLSPVIPRSKIIGVGRNYADHASE
LGNEVPHQPLLFVKPNTSVIGPDEPIVRPTASSNLHYEGELAIVIGRICKDVPEDRAQEVIFGFTVANDVTARDLQDSDG
HWVRAKGADTFCPLGPWMVTHFSIAEASHRQIVTRLDGREVQHGNTDQMVHTIPKLISYISSFMTLLPGDVILTGTPAGV
GPMELGQRVEVEIEGIGTLTNTVVEV
>Mature_266_residues
MRIARFVTAGSDPAFGIVELAADHGDHPETIAVITGDPVAAPVQYTGARHDLADVRLLSPVIPRSKIIGVGRNYADHASE
LGNEVPHQPLLFVKPNTSVIGPDEPIVRPTASSNLHYEGELAIVIGRICKDVPEDRAQEVIFGFTVANDVTARDLQDSDG
HWVRAKGADTFCPLGPWMVTHFSIAEASHRQIVTRLDGREVQHGNTDQMVHTIPKLISYISSFMTLLPGDVILTGTPAGV
GPMELGQRVEVEIEGIGTLTNTVVEV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=221, Percent_Identity=42.9864253393665, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI40786394, Length=221, Percent_Identity=42.9864253393665, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI13654274, Length=201, Percent_Identity=38.8059701492537, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=37.7450980392157, Blast_Score=148, Evalue=4e-36,
Organism=Homo sapiens, GI66348062, Length=194, Percent_Identity=39.1752577319588, Blast_Score=147, Evalue=7e-36,
Organism=Escherichia coli, GI1787428, Length=197, Percent_Identity=37.5634517766497, Blast_Score=147, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17557057, Length=190, Percent_Identity=42.6315789473684, Blast_Score=150, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6324161, Length=223, Percent_Identity=34.5291479820628, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28572127, Length=286, Percent_Identity=34.2657342657343, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24663695, Length=219, Percent_Identity=37.4429223744292, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI28571789, Length=203, Percent_Identity=33.4975369458128, Blast_Score=115, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 28656; Mature: 28656

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIARFVTAGSDPAFGIVELAADHGDHPETIAVITGDPVAAPVQYTGARHDLADVRLLSP
CCCEEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCEEECCCCCCHHHHHHHHC
VIPRSKIIGVGRNYADHASELGNEVPHQPLLFVKPNTSVIGPDEPIVRPTASSNLHYEGE
CCCCHHEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCCCEECCC
LAIVIGRICKDVPEDRAQEVIFGFTVANDVTARDLQDSDGHWVRAKGADTFCPLGPWMVT
CEEHHHHHHHCCCHHHHHHEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHH
HFSIAEASHRQIVTRLDGREVQHGNTDQMVHTIPKLISYISSFMTLLPGDVILTGTPAGV
EEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
GPMELGQRVEVEIEGIGTLTNTVVEV
CHHHCCCEEEEEEECCCHHHHHHCCC
>Mature Secondary Structure
MRIARFVTAGSDPAFGIVELAADHGDHPETIAVITGDPVAAPVQYTGARHDLADVRLLSP
CCCEEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCEEECCCCCCHHHHHHHHC
VIPRSKIIGVGRNYADHASELGNEVPHQPLLFVKPNTSVIGPDEPIVRPTASSNLHYEGE
CCCCHHEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCEECCCCCCCCCCCCCCCEECCC
LAIVIGRICKDVPEDRAQEVIFGFTVANDVTARDLQDSDGHWVRAKGADTFCPLGPWMVT
CEEHHHHHHHCCCHHHHHHEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHH
HFSIAEASHRQIVTRLDGREVQHGNTDQMVHTIPKLISYISSFMTLLPGDVILTGTPAGV
EEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
GPMELGQRVEVEIEGIGTLTNTVVEV
CHHHCCCEEEEEEECCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]