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The map label for this gene is lpa-14 [H]

Identifier: 50842772

GI number: 50842772

Start: 1403184

End: 1403912

Strand: Direct

Name: lpa-14 [H]

Synonym: PPA1291

Alternate gene names: 50842772

Gene position: 1403184-1403912 (Clockwise)

Preceding gene: 50842763

Following gene: 50842779

Centisome position: 54.81

GC content: 51.03

Gene sequence:

>729_bases
TTGATCTACATCTCTCGTGTGTCACTCGATACATTCCCCAAGAGTGCCTTGCCACAGCTGATGGAAAGAGCTAGTCCTGA
ACGACGAGATAGAGCACGAAGATACGTGCGAATCGATGACTGCTTGCGCTGCCTCATAGCTGACGAACTCCGGGCCTATT
CATTGAAGCTTGATTACAAGGTGCCAGTACAGTCAGAGGTATCGAAGAACGCTTTCGGGAAGCCGCTACTAGCAAACCGC
GATGGTCCTAAGTTCAACTTGTCGCACGATGGGAAGTGGATTGTCTGTGCCACAAGCCCACATCCTGTAGGCGTAGACGT
CGAGGCAGTCGCTGAGCCAGGTTTAGCGGTGGTCTCGAACGATTTTTCAGTGGAAGAAGTGGAGGCCTTGCGGACAACCG
CTACGGCTCCCCTCTCCATCGCTCGAGCGATGATCTGGACACGGAAGGAGGCATACCTCAAATATCTGGGGTTGGGTCTC
ACTGTTCAGTTAGATTCTTTTTCAGTAATAGATCAAACCTTGCTGTCGCCAGCTGAAGGGATGACAGACGGTATTCAGTT
TTATAGTTGGTGCGATGCCGATAACTCGCATGTGATCTCTGTCTGTGGCCACGGCGAGGAAGTCGTCATCTCTTGCGTCA
GCGGGCAAGAATTACTAGATGGACTGCCACCATCTCACTGTTCAGAAGAACCTCAAGAGCAACTTCGTTGGTTGCCCAAT
CTTAGTTAA

Upstream 100 bases:

>100_bases
ATGCGTGACCTCCCTAGTGATACACGCTGAAGTAACTTGTCACCTACTTCATGAGCTAGTCTATCTCCTTATAGGACCAC
ATAAAAGAGAGGACCAAAAA

Downstream 100 bases:

>100_bases
GATCATTTTGTAATTATCAAAATTCCAAGTCGCCTCGAGAAAAGCATTAACAGAGATCATATCTCACCAGGAGAGATGCG
GCTTAAATATCTCTTTCAAT

Product: biosurfactants production protein

Products: NA

Alternate protein names: Lipopeptide antibiotics iturin A and surfactin biosynthesis protein [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MIYISRVSLDTFPKSALPQLMERASPERRDRARRYVRIDDCLRCLIADELRAYSLKLDYKVPVQSEVSKNAFGKPLLANR
DGPKFNLSHDGKWIVCATSPHPVGVDVEAVAEPGLAVVSNDFSVEEVEALRTTATAPLSIARAMIWTRKEAYLKYLGLGL
TVQLDSFSVIDQTLLSPAEGMTDGIQFYSWCDADNSHVISVCGHGEEVVISCVSGQELLDGLPPSHCSEEPQEQLRWLPN
LS

Sequences:

>Translated_242_residues
MIYISRVSLDTFPKSALPQLMERASPERRDRARRYVRIDDCLRCLIADELRAYSLKLDYKVPVQSEVSKNAFGKPLLANR
DGPKFNLSHDGKWIVCATSPHPVGVDVEAVAEPGLAVVSNDFSVEEVEALRTTATAPLSIARAMIWTRKEAYLKYLGLGL
TVQLDSFSVIDQTLLSPAEGMTDGIQFYSWCDADNSHVISVCGHGEEVVISCVSGQELLDGLPPSHCSEEPQEQLRWLPN
LS
>Mature_242_residues
MIYISRVSLDTFPKSALPQLMERASPERRDRARRYVRIDDCLRCLIADELRAYSLKLDYKVPVQSEVSKNAFGKPLLANR
DGPKFNLSHDGKWIVCATSPHPVGVDVEAVAEPGLAVVSNDFSVEEVEALRTTATAPLSIARAMIWTRKEAYLKYLGLGL
TVQLDSFSVIDQTLLSPAEGMTDGIQFYSWCDADNSHVISVCGHGEEVVISCVSGQELLDGLPPSHCSEEPQEQLRWLPN
LS

Specific function: May activate the peptidyl carrier protein (PCP) domains of surfactin synthetase SRF1/2/3 and iturin A synthetase, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. Required for the coproduction of the lipopeptide a

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR004568 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 26807; Mature: 26807

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYISRVSLDTFPKSALPQLMERASPERRDRARRYVRIDDCLRCLIADELRAYSLKLDYK
CEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHEEEHHHHHHHHHHHHHHEEEEEEEEE
VPVQSEVSKNAFGKPLLANRDGPKFNLSHDGKWIVCATSPHPVGVDVEAVAEPGLAVVSN
CCCHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCHHHHCCCCEEEEEC
DFSVEEVEALRTTATAPLSIARAMIWTRKEAYLKYLGLGLTVQLDSFSVIDQTLLSPAEG
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCC
MTDGIQFYSWCDADNSHVISVCGHGEEVVISCVSGQELLDGLPPSHCSEEPQEQLRWLPN
CHHHHHEEEECCCCCCEEEEEECCCCEEEEEECCCHHHHHCCCCCCCCCCHHHHHHCCCC
LS
CC
>Mature Secondary Structure
MIYISRVSLDTFPKSALPQLMERASPERRDRARRYVRIDDCLRCLIADELRAYSLKLDYK
CEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHEEEHHHHHHHHHHHHHHEEEEEEEEE
VPVQSEVSKNAFGKPLLANRDGPKFNLSHDGKWIVCATSPHPVGVDVEAVAEPGLAVVSN
CCCHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCHHHHCCCCEEEEEC
DFSVEEVEALRTTATAPLSIARAMIWTRKEAYLKYLGLGLTVQLDSFSVIDQTLLSPAEG
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCC
MTDGIQFYSWCDADNSHVISVCGHGEEVVISCVSGQELLDGLPPSHCSEEPQEQLRWLPN
CHHHHHEEEECCCCCCEEEEEECCCCEEEEEECCCHHHHHCCCCCCCCCCHHHHHHCCCC
LS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8939709 [H]