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The map label for this gene is pdtaS [H]

Identifier: 50842743

GI number: 50842743

Start: 1371210

End: 1372685

Strand: Reverse

Name: pdtaS [H]

Synonym: PPA1265

Alternate gene names: 50842743

Gene position: 1372685-1371210 (Counterclockwise)

Preceding gene: 50842744

Following gene: 50842741

Centisome position: 53.61

GC content: 58.2

Gene sequence:

>1476_bases
ATGCCTGCCCTTAACCGCATCGTCGCCGACCGGACTCGTCTCGACGACGCCGATATCACCTGGCTCGAGGACCTCGTCGA
CGACTGGCAGATGCTTGCCGATACGTCGTTCTCCGACCTCATCTTGTGGGTTCCCGATAGGGACCCGAACGTGTTCTGGG
CCGTTGCCCAGGTGCGTCCAGATACTGGCCCGACTGCTCTGGAAGACGACGTCGTCGGTGAGTCTGTCGCTTATGACGAC
GAGAGTCTGGTCACCGAGGCCTTTATGAGCGCCGAGATGTGTGAAACCAGCGATAACAAATTGTCTGCAGGCATCCCGGT
TGATATCTGGGCAATTCCGGTCGTTCGTCGTGGGGAAGTCATCGCCGTCGTCGAAAGGCACACCAATCAGATGGGGGTGA
GGGCGCCGGGTAACACCGAGGACAACTACCTTGAAATCGCCGATATCCTCTCCGAAATGCTCCATCATGGTAGGTTCCCG
CAGTTTCCGGGCTCTGACCGAGCGCTTGCTCCGAAGGTCACTGACGGCGTGATCCGCGTGGCTGCCACGGGCATGATCAC
GTTTGCCAGCCCGAACGCGCTATCGGCATTTCGTCGTCTAGGCCTTGCCGGTGATTTGGATGGGGAATACCTCATTCCGA
CGGTGCGAGAGCTGTGTCCGAGGCTGCGTGAAGTCGGTCAATCGCTGACCCTGGACTTAGAAGGGCGCTGGCTCACCGAG
ACTGATATCGAAAACTCTGATGCCACTGTGCGGGCTCGCGTCATTCCGCTGCAGACCTGGCTTGACGATGTTGAGGTTTC
GGCTGGCACGTTGATCCTTATTCGTGATCTCACCGAGTTGCGGGACAGAGATCGCCAGCTCGTAACTAAAGATGCCACGA
TTAGGGAAATCCATCACCGGGTGAAGAATAACTTACAAACAGTTGCGGCACTGTTGCGGCTGCAGTCACGACGTATGAGT
AACTCGGACGCGAAGGATGCCCTGAAACAGGCCATGGGAAGGGTATCGGCCATTGCTGTCGTCCACGAGATTCTCTCGCA
GAACTTCGAGGAACAGGTGGCCTTTGACGAGGTTGCTGACCGTATCCTCCACATGGTCGGTGATGTGGCGGCTTCATCCG
GGTCGGTGGTAGCTCGACGGGAAGGCAGCTTTGGCGAGGTCCCTGCTGAGACTGCTACCGCGTTGTCGCTGGCGACGACA
GAGTTATGTCAAAACGCCATCGAGCATAGCCTGGATTCATCCTCTGGGAATGTCATCGTGCGGCCGCACCGCACCGATGA
CGCCCTTGTTGTCGACATTGTCAGCGACGGTAAACCGCTGCCAGAAGGGTTCTCGCTAGATAACCACCGCAGCTCGCTGG
GATTGTCAATCGTGACGACCTTGATGCAGGACCTCGGTGGCACGTTCACCCTCGAGGACAACTCCGACCGGGTCGGAACC
TGTGCCAGGCTCGTAATCCCGCTCCAGCGGCTGTGA

Upstream 100 bases:

>100_bases
TCTGCCGTATCGGGCGGTCTTGACCCAAATCGAATCACTCATTTTTGCTGATCTCGCTACCAGCTGGAGCTGGGTTGATT
TCTGTCACTAGAGTGACGGC

Downstream 100 bases:

>100_bases
CCATCGACGAGCGGAGAACTGTGAGCAGGTCAGGAACGACGCACGCGGGAGCGGGACTGACGACGTTTGATAGCGCGCCT
CTCGTCCTCGCTCATGCCGC

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MPALNRIVADRTRLDDADITWLEDLVDDWQMLADTSFSDLILWVPDRDPNVFWAVAQVRPDTGPTALEDDVVGESVAYDD
ESLVTEAFMSAEMCETSDNKLSAGIPVDIWAIPVVRRGEVIAVVERHTNQMGVRAPGNTEDNYLEIADILSEMLHHGRFP
QFPGSDRALAPKVTDGVIRVAATGMITFASPNALSAFRRLGLAGDLDGEYLIPTVRELCPRLREVGQSLTLDLEGRWLTE
TDIENSDATVRARVIPLQTWLDDVEVSAGTLILIRDLTELRDRDRQLVTKDATIREIHHRVKNNLQTVAALLRLQSRRMS
NSDAKDALKQAMGRVSAIAVVHEILSQNFEEQVAFDEVADRILHMVGDVAASSGSVVARREGSFGEVPAETATALSLATT
ELCQNAIEHSLDSSSGNVIVRPHRTDDALVVDIVSDGKPLPEGFSLDNHRSSLGLSIVTTLMQDLGGTFTLEDNSDRVGT
CARLVIPLQRL

Sequences:

>Translated_491_residues
MPALNRIVADRTRLDDADITWLEDLVDDWQMLADTSFSDLILWVPDRDPNVFWAVAQVRPDTGPTALEDDVVGESVAYDD
ESLVTEAFMSAEMCETSDNKLSAGIPVDIWAIPVVRRGEVIAVVERHTNQMGVRAPGNTEDNYLEIADILSEMLHHGRFP
QFPGSDRALAPKVTDGVIRVAATGMITFASPNALSAFRRLGLAGDLDGEYLIPTVRELCPRLREVGQSLTLDLEGRWLTE
TDIENSDATVRARVIPLQTWLDDVEVSAGTLILIRDLTELRDRDRQLVTKDATIREIHHRVKNNLQTVAALLRLQSRRMS
NSDAKDALKQAMGRVSAIAVVHEILSQNFEEQVAFDEVADRILHMVGDVAASSGSVVARREGSFGEVPAETATALSLATT
ELCQNAIEHSLDSSSGNVIVRPHRTDDALVVDIVSDGKPLPEGFSLDNHRSSLGLSIVTTLMQDLGGTFTLEDNSDRVGT
CARLVIPLQRL
>Mature_490_residues
PALNRIVADRTRLDDADITWLEDLVDDWQMLADTSFSDLILWVPDRDPNVFWAVAQVRPDTGPTALEDDVVGESVAYDDE
SLVTEAFMSAEMCETSDNKLSAGIPVDIWAIPVVRRGEVIAVVERHTNQMGVRAPGNTEDNYLEIADILSEMLHHGRFPQ
FPGSDRALAPKVTDGVIRVAATGMITFASPNALSAFRRLGLAGDLDGEYLIPTVRELCPRLREVGQSLTLDLEGRWLTET
DIENSDATVRARVIPLQTWLDDVEVSAGTLILIRDLTELRDRDRQLVTKDATIREIHHRVKNNLQTVAALLRLQSRRMSN
SDAKDALKQAMGRVSAIAVVHEILSQNFEEQVAFDEVADRILHMVGDVAASSGSVVARREGSFGEVPAETATALSLATTE
LCQNAIEHSLDSSSGNVIVRPHRTDDALVVDIVSDGKPLPEGFSLDNHRSSLGLSIVTTLMQDLGGTFTLEDNSDRVGTC
ARLVIPLQRL

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53900; Mature: 53769

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALNRIVADRTRLDDADITWLEDLVDDWQMLADTSFSDLILWVPDRDPNVFWAVAQVRP
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEECC
DTGPTALEDDVVGESVAYDDESLVTEAFMSAEMCETSDNKLSAGIPVDIWAIPVVRRGEV
CCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEECEEECCCE
IAVVERHTNQMGVRAPGNTEDNYLEIADILSEMLHHGRFPQFPGSDRALAPKVTDGVIRV
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHEE
AATGMITFASPNALSAFRRLGLAGDLDGEYLIPTVRELCPRLREVGQSLTLDLEGRWLTE
EECCEEEECCCHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHHHCCCCEEEEECCCEEEC
TDIENSDATVRARVIPLQTWLDDVEVSAGTLILIRDLTELRDRDRQLVTKDATIREIHHR
CCCCCCCCEEEEEEEEHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHH
VKNNLQTVAALLRLQSRRMSNSDAKDALKQAMGRVSAIAVVHEILSQNFEEQVAFDEVAD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RILHMVGDVAASSGSVVARREGSFGEVPAETATALSLATTELCQNAIEHSLDSSSGNVIV
HHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
RPHRTDDALVVDIVSDGKPLPEGFSLDNHRSSLGLSIVTTLMQDLGGTFTLEDNSDRVGT
ECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHH
CARLVIPLQRL
HHHHHHHHHCC
>Mature Secondary Structure 
PALNRIVADRTRLDDADITWLEDLVDDWQMLADTSFSDLILWVPDRDPNVFWAVAQVRP
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEECC
DTGPTALEDDVVGESVAYDDESLVTEAFMSAEMCETSDNKLSAGIPVDIWAIPVVRRGEV
CCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEECEEECCCE
IAVVERHTNQMGVRAPGNTEDNYLEIADILSEMLHHGRFPQFPGSDRALAPKVTDGVIRV
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHEE
AATGMITFASPNALSAFRRLGLAGDLDGEYLIPTVRELCPRLREVGQSLTLDLEGRWLTE
EECCEEEECCCHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHHHCCCCEEEEECCCEEEC
TDIENSDATVRARVIPLQTWLDDVEVSAGTLILIRDLTELRDRDRQLVTKDATIREIHHR
CCCCCCCCEEEEEEEEHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHH
VKNNLQTVAALLRLQSRRMSNSDAKDALKQAMGRVSAIAVVHEILSQNFEEQVAFDEVAD
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RILHMVGDVAASSGSVVARREGSFGEVPAETATALSLATTELCQNAIEHSLDSSSGNVIV
HHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
RPHRTDDALVVDIVSDGKPLPEGFSLDNHRSSLGLSIVTTLMQDLGGTFTLEDNSDRVGT
ECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHH
CARLVIPLQRL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]