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The map label for this gene is rho

Identifier: 50842733

GI number: 50842733

Start: 1357490

End: 1359391

Strand: Reverse

Name: rho

Synonym: PPA1254

Alternate gene names: 50842733

Gene position: 1359391-1357490 (Counterclockwise)

Preceding gene: 50842734

Following gene: 50842732

Centisome position: 53.1

GC content: 58.31

Gene sequence:

>1902_bases
GTGACTCAAACCTCACAGCCGGATGGATCCTTGGATCTGTCCACTAAGTTGCTCCCCGAGCTTCGTTCTATCGCTACTCA
GATGGGAATTAAGGGAGCTCGTGGTATGCGCAAGGCTGACCTCATCGCGGCTATCTCTGAAGGGGGATATCCGGGAGTCG
GGAGGCCAGCTGAGCGTCAGAATCGCGGTCAGGAATCCGGTACTTCTAGTGATGAGGGCCGGCAACAGCGCACCCAGCGA
CGCCGTCGCGCGGAGGCTTCTGAGGACTCCGAATTCAATAAATCTGCAGGGGGGAAGAAAACTCCGTCGGTAGGCGACCT
ACTCGACGCCGCCGAGGCTCAGAAACAAGCGGAAACAGCCAAGAAACCTGACGACCAAGATCCGGGTCAGCAGGATGGCG
GAGCTGATCGCCCGGGCCGTGAGCGCGGTGACCGCAGTCGTCGAGGCGATTCACCTCGACGACGAGCCCGCAATACCTCA
CGAGAAAATTTCAACAGCAATTCTGGCGACAGCAACATCAACGACGAGGTTGGTGCCCGGCTTGAAGCGCTGTCTCGCGG
TCAACGCGGTGAACGCAACCAGTCCGATCGTGGCCCTCAACATGATCACAACAACGACTCTTCTGTCGATTCCGACGACG
AGTACGGTCGGTTCTCGGAATACGGCAATGGCGGGCGACGTTCTCGCCGCCGTCGCCAGCGTGACCGTCAAAACCGTCGC
AAGCGTTCTAACGACCGCTACTCCGATTCAGAACCGAATGTGCGTGAGGACGACGTCCTTGTCCCGTGCTCGGGCATCCT
CGACATTCGTGACCAGTATGCCTTTGTGCGCACTTCGGGATATCTTCCTGGCGCCAATGATGCCTATGTCTCGATGGCTA
TAGTGCGTCGGCACCGCCTGCGCAAAGGCGACGTCATCGTCGGTCAGATGCGTGCTCATCGCGAAGGGGAGAGGCGTGAA
AAGTTCGCGCCGCTGGTCAAAATCGAGCAGGTTAATGGTGTTGATCCCGAGCAGATGAAGCAGCGTCCGGAGTTTTCTAA
GCTCACTCCGCTGTATCCGCAGGAACGTCTGCGTCTCGAGGACGACCCCAAAAACATGACTGGGCGGATCATCGATCTCG
TCAGTCCGATTGGTAAAGGCCAGCGCGGTCTCATCGTTTCGCCTCCAAAGGCTGGCAAGACGATGATCATGCAATCGATC
GCAAACTCGATCACTCGCAATAACCCCGAAGTTCACCTCATGGTGGTGTTGGTCGACGAGCGCCCCGAGGAGGTCACTGA
CTTCCAGCGCACTGTCAGCGGCGAGGTCGTCGCATCGACCTTCGACCGCCCTGCTGACGACCATACTCAGCTGTCCGAGC
TGGCCATCGAGCGTGCCAAACGTCTCGTAGAGCTTGGTCACGACGTCGTCATCTTGCTGGACGGCATCACTCGTCTGGGA
CGTGCGTACAACTTGGCCGCCCCTGCTTCCGGTCGGATCCTTTCCGGTGGTGTCGACTCAGCTGCCCTGTACCCGCCGAA
GAAGTTCTTTGGCGCTGCTCGTAATATCGAACACGGTGGGTCCCTGACGATCCTCGCCACCGCTCTGGTTGAGACCGGGT
CGAAGATGGACGAGGTGATCTTCGAGGAGTTCAAAGGCACTGGCAATATGGAGTTGCGGCTCCGTCGCGAATTTGCCAAT
AAGAGGCTGTTCCCTGCTATCGACGTTGACGCATCCGGTACCCGTCGCGAGGAATTGCTGCTGTCGCGCGAGGAGACAGC
GATTATGTGGAAGCTGCGCAGAGTGCTGTCTGGTCTGGAAGGCTCCCAGGCTCTCGAAATGATGCTTTCGCGGCTGCGTA
AGACCCAGACGAACGTGGAGTTCTTGTACACCATTTCGAAGACGACCCCGAACCAGGATTGA

Upstream 100 bases:

>100_bases
TGGTGTCAGCCGCCCGACCTATAGTCGATTCCGACGGCAGGCCCGATGAAACCGCGCCCACCGGACGTTATACCGGCCGG
GGCAGTTCGAAGGGACTTAC

Downstream 100 bases:

>100_bases
TGTCGTCAAGTGGACCGTGGCTGGCCGTCAGGGGTAAACTGACGCGCCGGTTCCGGTTCACGCCCGTTCGTACCAGTCGG
GCGACCCGGAGCGCGTTTGA

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MTQTSQPDGSLDLSTKLLPELRSIATQMGIKGARGMRKADLIAAISEGGYPGVGRPAERQNRGQESGTSSDEGRQQRTQR
RRRAEASEDSEFNKSAGGKKTPSVGDLLDAAEAQKQAETAKKPDDQDPGQQDGGADRPGRERGDRSRRGDSPRRRARNTS
RENFNSNSGDSNINDEVGARLEALSRGQRGERNQSDRGPQHDHNNDSSVDSDDEYGRFSEYGNGGRRSRRRRQRDRQNRR
KRSNDRYSDSEPNVREDDVLVPCSGILDIRDQYAFVRTSGYLPGANDAYVSMAIVRRHRLRKGDVIVGQMRAHREGERRE
KFAPLVKIEQVNGVDPEQMKQRPEFSKLTPLYPQERLRLEDDPKNMTGRIIDLVSPIGKGQRGLIVSPPKAGKTMIMQSI
ANSITRNNPEVHLMVVLVDERPEEVTDFQRTVSGEVVASTFDRPADDHTQLSELAIERAKRLVELGHDVVILLDGITRLG
RAYNLAAPASGRILSGGVDSAALYPPKKFFGAARNIEHGGSLTILATALVETGSKMDEVIFEEFKGTGNMELRLRREFAN
KRLFPAIDVDASGTRREELLLSREETAIMWKLRRVLSGLEGSQALEMMLSRLRKTQTNVEFLYTISKTTPNQD

Sequences:

>Translated_633_residues
MTQTSQPDGSLDLSTKLLPELRSIATQMGIKGARGMRKADLIAAISEGGYPGVGRPAERQNRGQESGTSSDEGRQQRTQR
RRRAEASEDSEFNKSAGGKKTPSVGDLLDAAEAQKQAETAKKPDDQDPGQQDGGADRPGRERGDRSRRGDSPRRRARNTS
RENFNSNSGDSNINDEVGARLEALSRGQRGERNQSDRGPQHDHNNDSSVDSDDEYGRFSEYGNGGRRSRRRRQRDRQNRR
KRSNDRYSDSEPNVREDDVLVPCSGILDIRDQYAFVRTSGYLPGANDAYVSMAIVRRHRLRKGDVIVGQMRAHREGERRE
KFAPLVKIEQVNGVDPEQMKQRPEFSKLTPLYPQERLRLEDDPKNMTGRIIDLVSPIGKGQRGLIVSPPKAGKTMIMQSI
ANSITRNNPEVHLMVVLVDERPEEVTDFQRTVSGEVVASTFDRPADDHTQLSELAIERAKRLVELGHDVVILLDGITRLG
RAYNLAAPASGRILSGGVDSAALYPPKKFFGAARNIEHGGSLTILATALVETGSKMDEVIFEEFKGTGNMELRLRREFAN
KRLFPAIDVDASGTRREELLLSREETAIMWKLRRVLSGLEGSQALEMMLSRLRKTQTNVEFLYTISKTTPNQD
>Mature_632_residues
TQTSQPDGSLDLSTKLLPELRSIATQMGIKGARGMRKADLIAAISEGGYPGVGRPAERQNRGQESGTSSDEGRQQRTQRR
RRAEASEDSEFNKSAGGKKTPSVGDLLDAAEAQKQAETAKKPDDQDPGQQDGGADRPGRERGDRSRRGDSPRRRARNTSR
ENFNSNSGDSNINDEVGARLEALSRGQRGERNQSDRGPQHDHNNDSSVDSDDEYGRFSEYGNGGRRSRRRRQRDRQNRRK
RSNDRYSDSEPNVREDDVLVPCSGILDIRDQYAFVRTSGYLPGANDAYVSMAIVRRHRLRKGDVIVGQMRAHREGERREK
FAPLVKIEQVNGVDPEQMKQRPEFSKLTPLYPQERLRLEDDPKNMTGRIIDLVSPIGKGQRGLIVSPPKAGKTMIMQSIA
NSITRNNPEVHLMVVLVDERPEEVTDFQRTVSGEVVASTFDRPADDHTQLSELAIERAKRLVELGHDVVILLDGITRLGR
AYNLAAPASGRILSGGVDSAALYPPKKFFGAARNIEHGGSLTILATALVETGSKMDEVIFEEFKGTGNMELRLRREFANK
RLFPAIDVDASGTRREELLLSREETAIMWKLRRVLSGLEGSQALEMMLSRLRKTQTNVEFLYTISKTTPNQD

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=364, Percent_Identity=56.3186813186813, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 70658; Mature: 70527

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTSQPDGSLDLSTKLLPELRSIATQMGIKGARGMRKADLIAAISEGGYPGVGRPAERQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHH
NRGQESGTSSDEGRQQRTQRRRRAEASEDSEFNKSAGGKKTPSVGDLLDAAEAQKQAETA
HCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
KKPDDQDPGQQDGGADRPGRERGDRSRRGDSPRRRARNTSRENFNSNSGDSNINDEVGAR
CCCCCCCCCCCCCCCCCCCHHHCCHHHCCCCHHHHHHCCCHHCCCCCCCCCCCCHHHHHH
LEALSRGQRGERNQSDRGPQHDHNNDSSVDSDDEYGRFSEYGNGGRRSRRRRQRDRQNRR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHH
KRSNDRYSDSEPNVREDDVLVPCSGILDIRDQYAFVRTSGYLPGANDAYVSMAIVRRHRL
HHCCCCCCCCCCCCCCCCEEECCCCHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHC
RKGDVIVGQMRAHREGERREKFAPLVKIEQVNGVDPEQMKQRPEFSKLTPLYPQERLRLE
CCCCEEEEHHHHHHCHHHHHHHCCCEEECCCCCCCHHHHHCCCCHHHCCCCCCHHHCCCC
DDPKNMTGRIIDLVSPIGKGQRGLIVSPPKAGKTMIMQSIANSITRNNPEVHLMVVLVDE
CCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECC
RPEEVTDFQRTVSGEVVASTFDRPADDHTQLSELAIERAKRLVELGHDVVILLDGITRLG
CCHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHH
RAYNLAAPASGRILSGGVDSAALYPPKKFFGAARNIEHGGSLTILATALVETGSKMDEVI
HHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHH
FEEFKGTGNMELRLRREFANKRLFPAIDVDASGTRREELLLSREETAIMWKLRRVLSGLE
HHHHCCCCCCEEEEHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GSQALEMMLSRLRKTQTNVEFLYTISKTTPNQD
CHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCC
>Mature Secondary Structure 
TQTSQPDGSLDLSTKLLPELRSIATQMGIKGARGMRKADLIAAISEGGYPGVGRPAERQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHH
NRGQESGTSSDEGRQQRTQRRRRAEASEDSEFNKSAGGKKTPSVGDLLDAAEAQKQAETA
HCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
KKPDDQDPGQQDGGADRPGRERGDRSRRGDSPRRRARNTSRENFNSNSGDSNINDEVGAR
CCCCCCCCCCCCCCCCCCCHHHCCHHHCCCCHHHHHHCCCHHCCCCCCCCCCCCHHHHHH
LEALSRGQRGERNQSDRGPQHDHNNDSSVDSDDEYGRFSEYGNGGRRSRRRRQRDRQNRR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHH
KRSNDRYSDSEPNVREDDVLVPCSGILDIRDQYAFVRTSGYLPGANDAYVSMAIVRRHRL
HHCCCCCCCCCCCCCCCCEEECCCCHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHC
RKGDVIVGQMRAHREGERREKFAPLVKIEQVNGVDPEQMKQRPEFSKLTPLYPQERLRLE
CCCCEEEEHHHHHHCHHHHHHHCCCEEECCCCCCCHHHHHCCCCHHHCCCCCCHHHCCCC
DDPKNMTGRIIDLVSPIGKGQRGLIVSPPKAGKTMIMQSIANSITRNNPEVHLMVVLVDE
CCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECC
RPEEVTDFQRTVSGEVVASTFDRPADDHTQLSELAIERAKRLVELGHDVVILLDGITRLG
CCHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHH
RAYNLAAPASGRILSGGVDSAALYPPKKFFGAARNIEHGGSLTILATALVETGSKMDEVI
HHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHH
FEEFKGTGNMELRLRREFANKRLFPAIDVDASGTRREELLLSREETAIMWKLRRVLSGLE
HHHHCCCCCCEEEEHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GSQALEMMLSRLRKTQTNVEFLYTISKTTPNQD
CHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8702978 [H]