Click here to switch to the map view.

The map label for this gene is murA [H]

Identifier: 50842706

GI number: 50842706

Start: 1333456

End: 1335102

Strand: Reverse

Name: murA [H]

Synonym: PPA1226

Alternate gene names: 50842706

Gene position: 1335102-1333456 (Counterclockwise)

Preceding gene: 50842708

Following gene: 50842704

Centisome position: 52.15

GC content: 58.89

Gene sequence:

>1647_bases
GTGACGAAGATCTCACTGAAGAGATCTCGACTGGCTTGCTCGACCCGTTCTTCCCGAGGGGAGGAACTCAGATCTGATAT
ATCCTGGTCAGGAAATGAGTTGTCGTCGAAAGGATCTGCTGTGGACAACATCACCCCAGCTTCGGTCGGTCGTCTTATCC
GCGACGCACGCAAGCAGCATGGAATGACGCAGAACCAATTGGCGGAGATCCTGAAGACCTCCCAGAGCGCTATCCACCGG
GTGGAATCAGGCACGCAGAACCTCTCTCTGGAGTACATCAACCGCATCGCGGAGGCGTTAGAGTCTCCCATCATCACCCA
GCCGGGAAGCGGTACCATGAATTACCGCATCGAAGGAGGTCATCAACTTTCGGGCTCTATCGAGGTGCGGTCCTCCAAAA
ACGCGGCCGTCGCGCTGCTATGCGCCTGTCTCATCAACAGGGGCCGTACCGTGCTACGCGGTATCGCCCACATCGAGGAG
GTTAACCGCATTCTTGAGGTGCTGACCTCCATCGGCGTCACCTACGAGTGGTCTGACGACGAGCATGATCTCACCCTGAT
TCGTCCGGCTGAGCTCAACCTTGACGATATGGACATCGAGGCTGCCCGACGTACCCGAAGCGTCATCATGTTCCTCGGAC
CGTTGATGCGGTTCTACGACACCTTCAAACTCCCCTACGCCGGCGGCTGCAACCTCGGCGCTCGAACTGTCGAACCTCAC
CTGCAGGTGCTACGTGCTTTCGGCCTTGACGTTGTTGCCACCGAGGGCTTTTACCAGTGCCACGTCACCGATCGCACCGT
CAAGGAGCGTCACATCGTCCTGACTGAGCGTGGCGACACTGTTACCGAGAATGCTCTGCTGGCTGCCGCCCAGACCCCCG
GCGTGACTGTGCTGCGTAATGCCAGCTCGAACTATATGGTTCAGGACTTGTGCGTGTTCCTATGCCAGCTCGGTGTGCAG
ATTGAGGGCATCGGAACGACGACCTTGCGAATCCGCGGCGTTGAAGAGATCGACGTTGATGTCGAGTACGCCCCGTCTGA
AGATCCGATTGAGGCTATGAGCCTCCTCACGGCGGCGGTCGTCACCAAGTCGGAGCTGACGATCACACGCTGCCCGATCG
AATTCCTTGAAATTGAGCTGGCGATCCTGTCTGAGATGGGTCTGGATTTCGACCTCTCCCCCGAGTACGTCTCTCGCAAC
GGGTTCACCCGTCTCGTTGATGTCACGGTGCGCCCCAGCAAGTTGCGAGCGGTAGCTGACAAAATCCACCCGATGCCCTT
CCCGGGCCTCAACATCGACAACCTACCGTTCTTTGCGGTTATTGCTGCGGAGGCAGAAGGCCAGACCCTCATCCATGACT
GGTGCTACGAGAATCGTGCGATCCACTTGCTCGACTTGGGCAAACTTGGCGCTGACGTTCAGCTGCTCGATCCGCACCGT
CTCATCGTGCGGGGCCCGACCCGTTGGCGTGGTCGCGAACTCATCTGCCCGCCGGCCTTGCGTCCTGCCGTCTGTCTGCT
ATTGGCCGCTCTGGCCGCTTCGGGAGAAACGACCCTGCGCGACGTCTACATGATCAACCGCGGTTACGAAGATCTCCCGA
CCCGGCTTGGGGCGTTGGGAGCCAAGATCACCGTCTTCCATGGCTGA

Upstream 100 bases:

>100_bases
GCGGCACGAATGGCGGCAACATAGCCACCGGGGCCGGCTCCAAGGACAACGACGTCAAAATGTGAGCTCATAGGTAACAC
TCTAGTGGGAACATCGGTCT

Downstream 100 bases:

>100_bases
GCCGCGGCGTCCTCGGGCCACCAGTCCAACTCGTCACCAGGATGCGCCACGGTGCGCTCGAGGACAGTATGTACGACACC
GGCTGCTTTACCGAGCGTGG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MTKISLKRSRLACSTRSSRGEELRSDISWSGNELSSKGSAVDNITPASVGRLIRDARKQHGMTQNQLAEILKTSQSAIHR
VESGTQNLSLEYINRIAEALESPIITQPGSGTMNYRIEGGHQLSGSIEVRSSKNAAVALLCACLINRGRTVLRGIAHIEE
VNRILEVLTSIGVTYEWSDDEHDLTLIRPAELNLDDMDIEAARRTRSVIMFLGPLMRFYDTFKLPYAGGCNLGARTVEPH
LQVLRAFGLDVVATEGFYQCHVTDRTVKERHIVLTERGDTVTENALLAAAQTPGVTVLRNASSNYMVQDLCVFLCQLGVQ
IEGIGTTTLRIRGVEEIDVDVEYAPSEDPIEAMSLLTAAVVTKSELTITRCPIEFLEIELAILSEMGLDFDLSPEYVSRN
GFTRLVDVTVRPSKLRAVADKIHPMPFPGLNIDNLPFFAVIAAEAEGQTLIHDWCYENRAIHLLDLGKLGADVQLLDPHR
LIVRGPTRWRGRELICPPALRPAVCLLLAALAASGETTLRDVYMINRGYEDLPTRLGALGAKITVFHG

Sequences:

>Translated_548_residues
MTKISLKRSRLACSTRSSRGEELRSDISWSGNELSSKGSAVDNITPASVGRLIRDARKQHGMTQNQLAEILKTSQSAIHR
VESGTQNLSLEYINRIAEALESPIITQPGSGTMNYRIEGGHQLSGSIEVRSSKNAAVALLCACLINRGRTVLRGIAHIEE
VNRILEVLTSIGVTYEWSDDEHDLTLIRPAELNLDDMDIEAARRTRSVIMFLGPLMRFYDTFKLPYAGGCNLGARTVEPH
LQVLRAFGLDVVATEGFYQCHVTDRTVKERHIVLTERGDTVTENALLAAAQTPGVTVLRNASSNYMVQDLCVFLCQLGVQ
IEGIGTTTLRIRGVEEIDVDVEYAPSEDPIEAMSLLTAAVVTKSELTITRCPIEFLEIELAILSEMGLDFDLSPEYVSRN
GFTRLVDVTVRPSKLRAVADKIHPMPFPGLNIDNLPFFAVIAAEAEGQTLIHDWCYENRAIHLLDLGKLGADVQLLDPHR
LIVRGPTRWRGRELICPPALRPAVCLLLAALAASGETTLRDVYMINRGYEDLPTRLGALGAKITVFHG
>Mature_547_residues
TKISLKRSRLACSTRSSRGEELRSDISWSGNELSSKGSAVDNITPASVGRLIRDARKQHGMTQNQLAEILKTSQSAIHRV
ESGTQNLSLEYINRIAEALESPIITQPGSGTMNYRIEGGHQLSGSIEVRSSKNAAVALLCACLINRGRTVLRGIAHIEEV
NRILEVLTSIGVTYEWSDDEHDLTLIRPAELNLDDMDIEAARRTRSVIMFLGPLMRFYDTFKLPYAGGCNLGARTVEPHL
QVLRAFGLDVVATEGFYQCHVTDRTVKERHIVLTERGDTVTENALLAAAQTPGVTVLRNASSNYMVQDLCVFLCQLGVQI
EGIGTTTLRIRGVEEIDVDVEYAPSEDPIEAMSLLTAAVVTKSELTITRCPIEFLEIELAILSEMGLDFDLSPEYVSRNG
FTRLVDVTVRPSKLRAVADKIHPMPFPGLNIDNLPFFAVIAAEAEGQTLIHDWCYENRAIHLLDLGKLGADVQLLDPHRL
IVRGPTRWRGRELICPPALRPAVCLLLAALAASGETTLRDVYMINRGYEDLPTRLGALGAKITVFHG

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=435, Percent_Identity=27.3563218390805, Blast_Score=166, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 60377; Mature: 60246

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKISLKRSRLACSTRSSRGEELRSDISWSGNELSSKGSAVDNITPASVGRLIRDARKQH
CCCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GMTQNQLAEILKTSQSAIHRVESGTQNLSLEYINRIAEALESPIITQPGSGTMNYRIEGG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEECCCCCEEEEEECCC
HQLSGSIEVRSSKNAAVALLCACLINRGRTVLRGIAHIEEVNRILEVLTSIGVTYEWSDD
EEECCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
EHDLTLIRPAELNLDDMDIEAARRTRSVIMFLGPLMRFYDTFKLPYAGGCNLGARTVEPH
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LQVLRAFGLDVVATEGFYQCHVTDRTVKERHIVLTERGDTVTENALLAAAQTPGVTVLRN
HHHHHHHCCEEEEECCEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEEC
ASSNYMVQDLCVFLCQLGVQIEGIGTTTLRIRGVEEIDVDVEYAPSEDPIEAMSLLTAAV
CCCCCHHHHHHHHHHHHCCEEEECCEEEEEEECCEEEEEEEEECCCCCHHHHHHHHHHHH
VTKSELTITRCPIEFLEIELAILSEMGLDFDLSPEYVSRNGFTRLVDVTVRPSKLRAVAD
HCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEEEECHHHHHHHHH
KIHPMPFPGLNIDNLPFFAVIAAEAEGQTLIHDWCYENRAIHLLDLGKLGADVQLLDPHR
HCCCCCCCCCCCCCCCEEEEEEECCCCCEEEHHHHCCCCEEEEEECCCCCCCEEEECCCE
LIVRGPTRWRGRELICPPALRPAVCLLLAALAASGETTLRDVYMINRGYEDLPTRLGALG
EEEECCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHEECCCCHHHHHHHHHCC
AKITVFHG
CEEEEEEC
>Mature Secondary Structure 
TKISLKRSRLACSTRSSRGEELRSDISWSGNELSSKGSAVDNITPASVGRLIRDARKQH
CCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GMTQNQLAEILKTSQSAIHRVESGTQNLSLEYINRIAEALESPIITQPGSGTMNYRIEGG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEECCCCCEEEEEECCC
HQLSGSIEVRSSKNAAVALLCACLINRGRTVLRGIAHIEEVNRILEVLTSIGVTYEWSDD
EEECCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
EHDLTLIRPAELNLDDMDIEAARRTRSVIMFLGPLMRFYDTFKLPYAGGCNLGARTVEPH
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LQVLRAFGLDVVATEGFYQCHVTDRTVKERHIVLTERGDTVTENALLAAAQTPGVTVLRN
HHHHHHHCCEEEEECCEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEEC
ASSNYMVQDLCVFLCQLGVQIEGIGTTTLRIRGVEEIDVDVEYAPSEDPIEAMSLLTAAV
CCCCCHHHHHHHHHHHHCCEEEECCEEEEEEECCEEEEEEEEECCCCCHHHHHHHHHHHH
VTKSELTITRCPIEFLEIELAILSEMGLDFDLSPEYVSRNGFTRLVDVTVRPSKLRAVAD
HCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEEEECHHHHHHHHH
KIHPMPFPGLNIDNLPFFAVIAAEAEGQTLIHDWCYENRAIHLLDLGKLGADVQLLDPHR
HCCCCCCCCCCCCCCCEEEEEEECCCCCEEEHHHHCCCCEEEEEECCCCCCCEEEECCCE
LIVRGPTRWRGRELICPPALRPAVCLLLAALAASGETTLRDVYMINRGYEDLPTRLGALG
EEEECCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHEECCCCHHHHHHHHHCC
AKITVFHG
CEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]