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The map label for this gene is cat2 [H]

Identifier: 50842698

GI number: 50842698

Start: 1325850

End: 1327067

Strand: Reverse

Name: cat2 [H]

Synonym: PPA1217

Alternate gene names: 50842698

Gene position: 1327067-1325850 (Counterclockwise)

Preceding gene: 50842703

Following gene: 50842696

Centisome position: 51.83

GC content: 58.29

Gene sequence:

>1218_bases
ATGATAAATTTAGCCGACCTCGAACGCGTTCTAAAAGGTGTGACAGGCCGACCTCGGGTGGTGTGTGCTGGTTCCGGTGC
CACTCCCCTGCCCCTCCTCGACGCCGTTGACCGATGCTTAGAGACGTGGCGATTTGCGTGTGTCAACGCCCCGGTTGGCG
TGCCGACGCGCAAAGGAGTCATTCACCAGACGGTCTTTATTGGTCCCGGATCCCGTCACGCTGAGAATCTCGAATATGTC
CCGTGCCGGTTGAGCCTTGCCCCACGACTCTACGAAGACCGTTTCGCCCCGGACATTCTCCTCCTCCACACCAGCACGCC
TCACAACGGCGCGGTGAGCATGGGCATTGAGGTGCAGGTTCTCCCCGCTGCGCTGGAATCAGCGAAACGCCGAGGAGCCC
TCGTTATTGCTCAGGTTAATCCCAGCATGCCCTATGTTTTCGGGGACGGAATTGTCGATGTTGACGACATCGATATCGGA
GTCATTGTCGACACCCCGTTGCCGACGGCCGCTATGCCGTCGCCTGGCCCGACTGCGTGGAGGATTGGCGAGCTCGTAGC
CTCCCGGGTACCCGACGGAGCAACCCTCCAAGTCGGTATCGGCGCTGTTCCTGACGCTGTGGTGGCGATGCTGCCTGATG
ATAGGGCCTTCGGCGTGTGGACTGAACTACTTACTGACTCGATCCGGCTGCTCGAGGAGGCTCACAGCCTTGACGACCGT
CTCCTCACCGGGACTTTCGCCATGGGAACGCCTGCCCTTTATGAATGGTTAGATGAAAACCCGCGAGTACAGTTGTTGCG
CTGCGAGAAAACGAATAATCCGAGTTTTATTGCAACTCAGCCGAAAATGGCTAGCATTAATGCGGCCCTGCAAGTCGACC
TGTTCGGCCAAGTCAACGCCACCCGGCTGCGCGGAAAAATCCATTCTGGGATCGGTGGGTCAACTGATTTCCTGGTCGGG
TCAATGCATTCCCCTGGCGGACAGGCGCTTATTGCCATGCTGAGTTGGCATCCAAAAGCTGACTGCTCGACGATTGTCGG
ACTGTTGGGCTCCCCTGCGTCAGCGACCCAGCCCTCGGTGGTCATCACCGAACAGGGCATCGCAGATCTTTTCGGGAAAT
CCCAAGAGGAGCAGGCGCGACAACTCATCGACAATGCCGCTCATCCTAATGCCCGAGAAAAACTCTGGCGCGAGGCCAAA
GAGCTATCCCTGGTCTGA

Upstream 100 bases:

>100_bases
TCTAGGAGCTGGTAGACGGGATGACATCAACTCTATTCTGCCAGTTTTTGTCATCATGCATGTGACCCGGTTGTGAGCCA
CTACTCTCTTTGTCGTGCGC

Downstream 100 bases:

>100_bases
CCTGTGGCCGTCACGTGATCGGGACGCGGGTACCTAGCAACGCGGCAAGGACCGTAATGACGCCGTTTTCGGTGTTCGGT
GGTGCCACGTAATTCGATGC

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MINLADLERVLKGVTGRPRVVCAGSGATPLPLLDAVDRCLETWRFACVNAPVGVPTRKGVIHQTVFIGPGSRHAENLEYV
PCRLSLAPRLYEDRFAPDILLLHTSTPHNGAVSMGIEVQVLPAALESAKRRGALVIAQVNPSMPYVFGDGIVDVDDIDIG
VIVDTPLPTAAMPSPGPTAWRIGELVASRVPDGATLQVGIGAVPDAVVAMLPDDRAFGVWTELLTDSIRLLEEAHSLDDR
LLTGTFAMGTPALYEWLDENPRVQLLRCEKTNNPSFIATQPKMASINAALQVDLFGQVNATRLRGKIHSGIGGSTDFLVG
SMHSPGGQALIAMLSWHPKADCSTIVGLLGSPASATQPSVVITEQGIADLFGKSQEEQARQLIDNAAHPNAREKLWREAK
ELSLV

Sequences:

>Translated_405_residues
MINLADLERVLKGVTGRPRVVCAGSGATPLPLLDAVDRCLETWRFACVNAPVGVPTRKGVIHQTVFIGPGSRHAENLEYV
PCRLSLAPRLYEDRFAPDILLLHTSTPHNGAVSMGIEVQVLPAALESAKRRGALVIAQVNPSMPYVFGDGIVDVDDIDIG
VIVDTPLPTAAMPSPGPTAWRIGELVASRVPDGATLQVGIGAVPDAVVAMLPDDRAFGVWTELLTDSIRLLEEAHSLDDR
LLTGTFAMGTPALYEWLDENPRVQLLRCEKTNNPSFIATQPKMASINAALQVDLFGQVNATRLRGKIHSGIGGSTDFLVG
SMHSPGGQALIAMLSWHPKADCSTIVGLLGSPASATQPSVVITEQGIADLFGKSQEEQARQLIDNAAHPNAREKLWREAK
ELSLV
>Mature_405_residues
MINLADLERVLKGVTGRPRVVCAGSGATPLPLLDAVDRCLETWRFACVNAPVGVPTRKGVIHQTVFIGPGSRHAENLEYV
PCRLSLAPRLYEDRFAPDILLLHTSTPHNGAVSMGIEVQVLPAALESAKRRGALVIAQVNPSMPYVFGDGIVDVDDIDIG
VIVDTPLPTAAMPSPGPTAWRIGELVASRVPDGATLQVGIGAVPDAVVAMLPDDRAFGVWTELLTDSIRLLEEAHSLDDR
LLTGTFAMGTPALYEWLDENPRVQLLRCEKTNNPSFIATQPKMASINAALQVDLFGQVNATRLRGKIHSGIGGSTDFLVG
SMHSPGGQALIAMLSWHPKADCSTIVGLLGSPASATQPSVVITEQGIADLFGKSQEEQARQLIDNAAHPNAREKLWREAK
ELSLV

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=262, Percent_Identity=29.3893129770992, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17538151, Length=424, Percent_Identity=30.6603773584906, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32563853, Length=430, Percent_Identity=30, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319456, Length=228, Percent_Identity=30.7017543859649, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358615, Length=411, Percent_Identity=32.8467153284672, Blast_Score=193, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 43307; Mature: 43307

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLADLERVLKGVTGRPRVVCAGSGATPLPLLDAVDRCLETWRFACVNAPVGVPTRKGV
CCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCE
IHQTVFIGPGSRHAENLEYVPCRLSLAPRLYEDRFAPDILLLHTSTPHNGAVSMGIEVQV
EEEEEEECCCCCCCCCCEEEEEEEECCCHHHHHCCCCCEEEEEECCCCCCEEEECEEEEE
LPAALESAKRRGALVIAQVNPSMPYVFGDGIVDVDDIDIGVIVDTPLPTAAMPSPGPTAW
EHHHHHHHHHCCCEEEEEECCCCCEEECCCEEEECCCEEEEEECCCCCCCCCCCCCCCHH
RIGELVASRVPDGATLQVGIGAVPDAVVAMLPDDRAFGVWTELLTDSIRLLEEAHSLDDR
HHHHHHHHHCCCCCEEEEECCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
LLTGTFAMGTPALYEWLDENPRVQLLRCEKTNNPSFIATQPKMASINAALQVDLFGQVNA
EEECCHHCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCEECCEEEEEEEECCCCH
TRLRGKIHSGIGGSTDFLVGSMHSPGGQALIAMLSWHPKADCSTIVGLLGSPASATQPSV
HHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEE
VITEQGIADLFGKSQEEQARQLIDNAAHPNAREKLWREAKELSLV
EEECCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINLADLERVLKGVTGRPRVVCAGSGATPLPLLDAVDRCLETWRFACVNAPVGVPTRKGV
CCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCE
IHQTVFIGPGSRHAENLEYVPCRLSLAPRLYEDRFAPDILLLHTSTPHNGAVSMGIEVQV
EEEEEEECCCCCCCCCCEEEEEEEECCCHHHHHCCCCCEEEEEECCCCCCEEEECEEEEE
LPAALESAKRRGALVIAQVNPSMPYVFGDGIVDVDDIDIGVIVDTPLPTAAMPSPGPTAW
EHHHHHHHHHCCCEEEEEECCCCCEEECCCEEEECCCEEEEEECCCCCCCCCCCCCCCHH
RIGELVASRVPDGATLQVGIGAVPDAVVAMLPDDRAFGVWTELLTDSIRLLEEAHSLDDR
HHHHHHHHHCCCCCEEEEECCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
LLTGTFAMGTPALYEWLDENPRVQLLRCEKTNNPSFIATQPKMASINAALQVDLFGQVNA
EEECCHHCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCEECCEEEEEEEECCCCH
TRLRGKIHSGIGGSTDFLVGSMHSPGGQALIAMLSWHPKADCSTIVGLLGSPASATQPSV
HHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEE
VITEQGIADLFGKSQEEQARQLIDNAAHPNAREKLWREAKELSLV
EEECCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]