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The map label for this gene is rnd [H]

Identifier: 50842545

GI number: 50842545

Start: 1158598

End: 1159836

Strand: Reverse

Name: rnd [H]

Synonym: PPA1063

Alternate gene names: 50842545

Gene position: 1159836-1158598 (Counterclockwise)

Preceding gene: 50842546

Following gene: 50842540

Centisome position: 45.3

GC content: 61.74

Gene sequence:

>1239_bases
GTGAGCGACCTCCCTATCCTTGCTGAACCTCGCGAGGGAGTGCCGCCGGTCGTCAACACTCCCGACAGTCTCACGCACAC
CTGTCGGGCCCTCAGTAACGGGCATGGTCCGATTGCGATCGACACTGAACGAGCCCACGGGTTTCGCTATAGCCCCCGGG
CTTGCCTCATCCAGCTACGCCGAGACGGATCGGGCACACACCTCGTCGATCCCCTCGCTCTCGGTGGAGCCGTCGGCCTC
AAGCCTCTCGCCAAGGCGCTGGCTGGAACCCAGTGGATTCTTCACGCCGCCACGCAGGACATGCCCTGCCTTGCCATGGA
CGGCCTGCGTCCTGATGACCTCTTCGACACTGAACTGGCAGGTCGTCTTCTCAACCTGCCGAGGGTCAGCCTGGGCCCGA
TGGTCGAGCGTTACTGCGGAGTGACCCTACTTAAGGAGCACTCCGCCTCTGATTGGTCGCGTCGACCCCTCCCCCGCGAT
TGGCAGGTGTACGCGGCCCTTGACGTCGAACTCCTCAACGACCTCAGGGAAAAGATCCTTAGCGATCTTCATGAAGCTGG
AAAAGAAGAATGGGCTCGTCAGGAATTTGCCCATCTTGTCGAGGTAGCAGCGGACTTGCCGAGCGAGGAACCAGGAATCG
ATCCGAAGCGCTGGCGCAAGCTTAGCCATATCGGTGATATTCACAGTCGGGCTGGACTGCAATTAGCGCACGATCTGTGG
CTAGCACGAGAGAACCTCGCCCATGACCTCGATATTATGCCCGGACGTCTGCTCCGTGACGAAGCCTTGGTCGCCGCGGC
TCGTCACTGCGACCGCACTGGCAACGTTGACGTCGAAACAGTTCTTGCCATCAGGGGATTTCATCGAGGACGGGCGAAAA
AGTACCGCCAAACCTGGGCCGAGGCCATCAACCACGCACGAAGCGTGTCACCGACGAAGTATCCGCCGTTGCGGGAGCCA
TCCTCAGGCATCCCCCACCCCCGGTCGTGGGAGCGCCATCATCCGGAGGAAGCCGCACGGTGGGCAGCCGTAAGACCAGC
CGTCAACGACGTGGCCGCCGACCATGACGTCCCACCCGAAAACCTCTGCACCCCAACATGGCTGAGGCATTTTGCATGGC
AACCGCCTGAGGATTGTTCAGTCGAGGGGGTTGACGTTTTCCTGGAGGGGCTCGGCGCACGGCCGTGGCAACGGGAGATT
CTCTCGGGGCCGCTAAGCGCGGTTATGGCCACGCTGTGA

Upstream 100 bases:

>100_bases
CCCATTTGGGATCATGGAGTGACCTCTGCCTGCTCTCCTGCGGGGTCTCTCCCATTCCCGACGACATTGCCGCCATCTCT
CCCCGACGGGCCGAATTCGC

Downstream 100 bases:

>100_bases
ATCCCGGCATCCCCTTCACGAGTACTCACCATCAAGTTGGGCAACCAGTTGGCTGACGGCATCAGCGATACCTCGAGAAT
CTAAACCAAGCTCAGCCATG

Product: ribonuclease D

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSDLPILAEPREGVPPVVNTPDSLTHTCRALSNGHGPIAIDTERAHGFRYSPRACLIQLRRDGSGTHLVDPLALGGAVGL
KPLAKALAGTQWILHAATQDMPCLAMDGLRPDDLFDTELAGRLLNLPRVSLGPMVERYCGVTLLKEHSASDWSRRPLPRD
WQVYAALDVELLNDLREKILSDLHEAGKEEWARQEFAHLVEVAADLPSEEPGIDPKRWRKLSHIGDIHSRAGLQLAHDLW
LARENLAHDLDIMPGRLLRDEALVAAARHCDRTGNVDVETVLAIRGFHRGRAKKYRQTWAEAINHARSVSPTKYPPLREP
SSGIPHPRSWERHHPEEAARWAAVRPAVNDVAADHDVPPENLCTPTWLRHFAWQPPEDCSVEGVDVFLEGLGARPWQREI
LSGPLSAVMATL

Sequences:

>Translated_412_residues
MSDLPILAEPREGVPPVVNTPDSLTHTCRALSNGHGPIAIDTERAHGFRYSPRACLIQLRRDGSGTHLVDPLALGGAVGL
KPLAKALAGTQWILHAATQDMPCLAMDGLRPDDLFDTELAGRLLNLPRVSLGPMVERYCGVTLLKEHSASDWSRRPLPRD
WQVYAALDVELLNDLREKILSDLHEAGKEEWARQEFAHLVEVAADLPSEEPGIDPKRWRKLSHIGDIHSRAGLQLAHDLW
LARENLAHDLDIMPGRLLRDEALVAAARHCDRTGNVDVETVLAIRGFHRGRAKKYRQTWAEAINHARSVSPTKYPPLREP
SSGIPHPRSWERHHPEEAARWAAVRPAVNDVAADHDVPPENLCTPTWLRHFAWQPPEDCSVEGVDVFLEGLGARPWQREI
LSGPLSAVMATL
>Mature_411_residues
SDLPILAEPREGVPPVVNTPDSLTHTCRALSNGHGPIAIDTERAHGFRYSPRACLIQLRRDGSGTHLVDPLALGGAVGLK
PLAKALAGTQWILHAATQDMPCLAMDGLRPDDLFDTELAGRLLNLPRVSLGPMVERYCGVTLLKEHSASDWSRRPLPRDW
QVYAALDVELLNDLREKILSDLHEAGKEEWARQEFAHLVEVAADLPSEEPGIDPKRWRKLSHIGDIHSRAGLQLAHDLWL
ARENLAHDLDIMPGRLLRDEALVAAARHCDRTGNVDVETVLAIRGFHRGRAKKYRQTWAEAINHARSVSPTKYPPLREPS
SGIPHPRSWERHHPEEAARWAAVRPAVNDVAADHDVPPENLCTPTWLRHFAWQPPEDCSVEGVDVFLEGLGARPWQREIL
SGPLSAVMATL

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=353, Percent_Identity=26.628895184136, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 45789; Mature: 45658

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLPILAEPREGVPPVVNTPDSLTHTCRALSNGHGPIAIDTERAHGFRYSPRACLIQLR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHEEC
RDGSGTHLVDPLALGGAVGLKPLAKALAGTQWILHAATQDMPCLAMDGLRPDDLFDTELA
CCCCCCEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHH
GRLLNLPRVSLGPMVERYCGVTLLKEHSASDWSRRPLPRDWQVYAALDVELLNDLREKIL
HHHHCCCCCHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
SDLHEAGKEEWARQEFAHLVEVAADLPSEEPGIDPKRWRKLSHIGDIHSRAGLQLAHDLW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LARENLAHDLDIMPGRLLRDEALVAAARHCDRTGNVDVETVLAIRGFHRGRAKKYRQTWA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EAINHARSVSPTKYPPLREPSSGIPHPRSWERHHPEEAARWAAVRPAVNDVAADHDVPPE
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
NLCTPTWLRHFAWQPPEDCSVEGVDVFLEGLGARPWQREILSGPLSAVMATL
HCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDLPILAEPREGVPPVVNTPDSLTHTCRALSNGHGPIAIDTERAHGFRYSPRACLIQLR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHEEC
RDGSGTHLVDPLALGGAVGLKPLAKALAGTQWILHAATQDMPCLAMDGLRPDDLFDTELA
CCCCCCEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHH
GRLLNLPRVSLGPMVERYCGVTLLKEHSASDWSRRPLPRDWQVYAALDVELLNDLREKIL
HHHHCCCCCHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
SDLHEAGKEEWARQEFAHLVEVAADLPSEEPGIDPKRWRKLSHIGDIHSRAGLQLAHDLW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LARENLAHDLDIMPGRLLRDEALVAAARHCDRTGNVDVETVLAIRGFHRGRAKKYRQTWA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EAINHARSVSPTKYPPLREPSSGIPHPRSWERHHPEEAARWAAVRPAVNDVAADHDVPPE
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
NLCTPTWLRHFAWQPPEDCSVEGVDVFLEGLGARPWQREILSGPLSAVMATL
HCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]