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The map label for this gene is ygcA [C]

Identifier: 50842542

GI number: 50842542

Start: 1152135

End: 1153316

Strand: Direct

Name: ygcA [C]

Synonym: PPA1060

Alternate gene names: 50842542

Gene position: 1152135-1153316 (Clockwise)

Preceding gene: 50842541

Following gene: 50842543

Centisome position: 45.0

GC content: 60.74

Gene sequence:

>1182_bases
ATGCATGAGTCTGTTGGTGCGTCCCAGGGCGATGAATTCGACCTTGGCATGGGCAATATCGCTCACGGTGGTTATTGCGT
GGCGCGTCTCGATGGCAGGGTAGTCTTCGTCCGCGGCGCGTTGCCGGGGGAGGAGGTCCGGGTTCGGCTGACCGACATAT
CGAAGGCTTCGCACTGGTTTGGACAGGCTGTCGACGTCATCTCGGCCGATTCGCATCGCGTTGTTCCGCCATGCCCAGTG
GCGGGAGAGTGTGGGGGTTGCGACTTCCAACACGTCGATGTTGAGTTTCAGCGCGAGCTTAAGCGGCGTGTCGTCGCTGA
GCAACTCAGTCGCCTCGCTGGGATTAAGTGGGCGGGGACTGTGGAGGCTGTTACCGGTTCCTCCGATGGTCTGGGCTGGC
GTACGCGCATGCAGTATCGCAGCCTCAACCAGCGTCCAGCGCTGCGTCGTCATCGTAGTCATGATTTAGTACAAGTTCCC
GAAGGCGGTTGCCCGATCGCGCACCCTGCGGGCCGCCCTGCTGCTGAAGCTGCCTGTAATACGGCTGAGCACGCGATTGT
CATGGTGACTAGTTGTCTAAGCGAGGATCCGGAAGTGAGCGTCATCGCAGATGGGCAGCTTGTTGCTGGCGGTGAGACAA
TGACAGCTCGTGTTGGCCAGCGTCGGTGGAAGGTCGGCGCTGGTGGGTTTTGGCAGGTGCATCCGGGGGCTGCTGAAGCC
TTGGCGGATGCAGTTATCGGTAGCCTGGAACCCCAGCAGGGTGACGAAGCTCTTGATCTGTATTGCGGTGTTGGACTCTT
CGCAGGACTCTTGGCCGATCGTGGAGTTCGAGTCCGTGGTGTTGAGGTATCGCGTCAGGCAGTTGCGTTGGCGCGACGCA
ATGTGCCGGGCGGCCGTTTCACCGCTGGCCGCGTGGAGCGAGTGCTACCTCGGATGGCGCCTAAAGCCAACATTGTGGTG
CTGGATCCGCCACGCAAGGGTGCTGGGAAAACTGTCGTCCAGGCTGTGGCTCGGACTTCGCCTCGGGCGATCGCTCATGT
CGCCTGTGACCCGGCCGCCTTGGCTCGCGATCTGCACTTGTTCGACGTCAACGGGTATCTGCCTCGATCAATCCGTGCTT
TTGACGTCTTCCCGATGACTCATCACGTCGAAGCCGTGGCGATTCTGGAACCGAAGATCTGA

Upstream 100 bases:

>100_bases
AAAGCGTTGGAAGCGTAACGATCCTCGTTCTTGGCGTGATCCTGGTGCCACCATCACTCCCCGGCGTTGAGATGCCACCG
AGGGCCTTAGACTTAGATAA

Downstream 100 bases:

>100_bases
GATGACAGGTCCAGTTCCGAAATGTCCGCTACGTCCCGGGGATCCATGCAGTCTGTGTCAGCTGTACGTGACGGGTCCGC
AAGATTGCGGGTTGGTGTAC

Product: SAM-dependent methyltransferase related to tRNA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MHESVGASQGDEFDLGMGNIAHGGYCVARLDGRVVFVRGALPGEEVRVRLTDISKASHWFGQAVDVISADSHRVVPPCPV
AGECGGCDFQHVDVEFQRELKRRVVAEQLSRLAGIKWAGTVEAVTGSSDGLGWRTRMQYRSLNQRPALRRHRSHDLVQVP
EGGCPIAHPAGRPAAEAACNTAEHAIVMVTSCLSEDPEVSVIADGQLVAGGETMTARVGQRRWKVGAGGFWQVHPGAAEA
LADAVIGSLEPQQGDEALDLYCGVGLFAGLLADRGVRVRGVEVSRQAVALARRNVPGGRFTAGRVERVLPRMAPKANIVV
LDPPRKGAGKTVVQAVARTSPRAIAHVACDPAALARDLHLFDVNGYLPRSIRAFDVFPMTHHVEAVAILEPKI

Sequences:

>Translated_393_residues
MHESVGASQGDEFDLGMGNIAHGGYCVARLDGRVVFVRGALPGEEVRVRLTDISKASHWFGQAVDVISADSHRVVPPCPV
AGECGGCDFQHVDVEFQRELKRRVVAEQLSRLAGIKWAGTVEAVTGSSDGLGWRTRMQYRSLNQRPALRRHRSHDLVQVP
EGGCPIAHPAGRPAAEAACNTAEHAIVMVTSCLSEDPEVSVIADGQLVAGGETMTARVGQRRWKVGAGGFWQVHPGAAEA
LADAVIGSLEPQQGDEALDLYCGVGLFAGLLADRGVRVRGVEVSRQAVALARRNVPGGRFTAGRVERVLPRMAPKANIVV
LDPPRKGAGKTVVQAVARTSPRAIAHVACDPAALARDLHLFDVNGYLPRSIRAFDVFPMTHHVEAVAILEPKI
>Mature_393_residues
MHESVGASQGDEFDLGMGNIAHGGYCVARLDGRVVFVRGALPGEEVRVRLTDISKASHWFGQAVDVISADSHRVVPPCPV
AGECGGCDFQHVDVEFQRELKRRVVAEQLSRLAGIKWAGTVEAVTGSSDGLGWRTRMQYRSLNQRPALRRHRSHDLVQVP
EGGCPIAHPAGRPAAEAACNTAEHAIVMVTSCLSEDPEVSVIADGQLVAGGETMTARVGQRRWKVGAGGFWQVHPGAAEA
LADAVIGSLEPQQGDEALDLYCGVGLFAGLLADRGVRVRGVEVSRQAVALARRNVPGGRFTAGRVERVLPRMAPKANIVV
LDPPRKGAGKTVVQAVARTSPRAIAHVACDPAALARDLHLFDVNGYLPRSIRAFDVFPMTHHVEAVAILEPKI

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=186, Percent_Identity=31.7204301075269, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI51173878, Length=186, Percent_Identity=31.7204301075269, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1789148, Length=430, Percent_Identity=26.7441860465116, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1787083, Length=166, Percent_Identity=25.3012048192771, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 41992; Mature: 41992

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHESVGASQGDEFDLGMGNIAHGGYCVARLDGRVVFVRGALPGEEVRVRLTDISKASHWF
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCEEEEEEECCHHHHHH
GQAVDVISADSHRVVPPCPVAGECGGCDFQHVDVEFQRELKRRVVAEQLSRLAGIKWAGT
HHHHHEEECCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCE
VEAVTGSSDGLGWRTRMQYRSLNQRPALRRHRSHDLVQVPEGGCPIAHPAGRPAAEAACN
EEEEECCCCCCCHHHHHHHHCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHC
TAEHAIVMVTSCLSEDPEVSVIADGQLVAGGETMTARVGQRRWKVGAGGFWQVHPGAAEA
CHHHHEEEEEHHHCCCCCEEEEECCEEEECCCHHHHHHCCHHEEECCCCEEEECCCHHHH
LADAVIGSLEPQQGDEALDLYCGVGLFAGLLADRGVRVRGVEVSRQAVALARRNVPGGRF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCCC
TAGRVERVLPRMAPKANIVVLDPPRKGAGKTVVQAVARTSPRAIAHVACDPAALARDLHL
CHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHCEEEE
FDVNGYLPRSIRAFDVFPMTHHVEAVAILEPKI
EECCCCCCCCEEEEEECCCHHCCEEEEEECCCC
>Mature Secondary Structure
MHESVGASQGDEFDLGMGNIAHGGYCVARLDGRVVFVRGALPGEEVRVRLTDISKASHWF
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCCCEEEEEEECCHHHHHH
GQAVDVISADSHRVVPPCPVAGECGGCDFQHVDVEFQRELKRRVVAEQLSRLAGIKWAGT
HHHHHEEECCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCE
VEAVTGSSDGLGWRTRMQYRSLNQRPALRRHRSHDLVQVPEGGCPIAHPAGRPAAEAACN
EEEEECCCCCCCHHHHHHHHCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHC
TAEHAIVMVTSCLSEDPEVSVIADGQLVAGGETMTARVGQRRWKVGAGGFWQVHPGAAEA
CHHHHEEEEEHHHCCCCCEEEEECCEEEECCCHHHHHHCCHHEEECCCCEEEECCCHHHH
LADAVIGSLEPQQGDEALDLYCGVGLFAGLLADRGVRVRGVEVSRQAVALARRNVPGGRF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCCC
TAGRVERVLPRMAPKANIVVLDPPRKGAGKTVVQAVARTSPRAIAHVACDPAALARDLHL
CHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHCEEEE
FDVNGYLPRSIRAFDVFPMTHHVEAVAILEPKI
EECCCCCCCCEEEEEECCCHHCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]