Click here to switch to the map view.

The map label for this gene is glpR [H]

Identifier: 50842493

GI number: 50842493

Start: 1093621

End: 1094424

Strand: Reverse

Name: glpR [H]

Synonym: PPA1010

Alternate gene names: 50842493

Gene position: 1094424-1093621 (Counterclockwise)

Preceding gene: 50842498

Following gene: 50842488

Centisome position: 42.75

GC content: 59.95

Gene sequence:

>804_bases
ATGCCATCGGACGCCCATTCGACGTCTTCTCGCCGCAATGATCGTATGGTGGCCATTTTGGCTATGCTACGGGATCGCGA
CGAGGTTCCCCTCCGCGACATGGCATCAGCCTTGGGGGCCAGTGCGGCCACGATCCGGCGTGATGTCGTCTCCTTGGCCG
AGCAAGGCTTGCTTATTCGTTCACACGGAACTGCGCGTCGCGCCGGAACTGGCGCCGAACTACCCGTCAATCTACGGGAC
GGTCGCCGTCGTCGTGCCAAAGAAGCCATTGCCCACGCCGTAGCTTCCGAACTGCCGATCGGACGTCACGCTATTGGTCT
GACCGGCGGAACCACGACAACCGAAATCGTCCGGGCCCTGCATCATCGCCACGACCTGACCCTCATTACAAACTCCGTCA
GCATTGCCCTCGAAGCTGCTAGTCAGGGCCAGCAGAGGGTCCTGATTACTGGTGGGGTTCTGCGACCATCTTCCCTCGAG
CTCGTCGGTTCCTTGGCCGAATCCACCTTCAAACAGGTCAATGTCGGAACAGCCATCGTCGGCTGCGACGGCATGAGCGC
CGAGGGTGGTCTGACGACTCATGACGGTATCGAGGCAGCTACTAACCACACCATGATCAAACGGGCAGCACACATTATTG
CGGCTGTCGATGGGTCGAAAATCGGTCGAGTAACCCTCGCCAAACTGGCTGAGGCCAAGGACGTCGACCTCCTCATTACA
GACGACTCTGCTGACCCCGAAGAACTAGCCCGGCTGCGCGCACTGGGTATCGCGATTCGAATCGTCCACGCGCCCATCGA
CTGA

Upstream 100 bases:

>100_bases
TGCTGCACCCTTGCTCCCATCACTGCTACCAGCACGGTAGGATCAGCACAGAAACGCTCACAATGTCACGCAAGCCCGTC
AGGCGAACTGGGAGGGGACA

Downstream 100 bases:

>100_bases
CGGTCCCTCGGCCACCCGCTAGCGCGCTAACTATCCGCTGTCTCGTCCTAAATGTAGACGTTCCCGGTCCCGGGACCGGG
AACCTGACAAGCTTGGTACG

Product: putative transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MPSDAHSTSSRRNDRMVAILAMLRDRDEVPLRDMASALGASAATIRRDVVSLAEQGLLIRSHGTARRAGTGAELPVNLRD
GRRRRAKEAIAHAVASELPIGRHAIGLTGGTTTTEIVRALHHRHDLTLITNSVSIALEAASQGQQRVLITGGVLRPSSLE
LVGSLAESTFKQVNVGTAIVGCDGMSAEGGLTTHDGIEAATNHTMIKRAAHIIAAVDGSKIGRVTLAKLAEAKDVDLLIT
DDSADPEELARLRALGIAIRIVHAPID

Sequences:

>Translated_267_residues
MPSDAHSTSSRRNDRMVAILAMLRDRDEVPLRDMASALGASAATIRRDVVSLAEQGLLIRSHGTARRAGTGAELPVNLRD
GRRRRAKEAIAHAVASELPIGRHAIGLTGGTTTTEIVRALHHRHDLTLITNSVSIALEAASQGQQRVLITGGVLRPSSLE
LVGSLAESTFKQVNVGTAIVGCDGMSAEGGLTTHDGIEAATNHTMIKRAAHIIAAVDGSKIGRVTLAKLAEAKDVDLLIT
DDSADPEELARLRALGIAIRIVHAPID
>Mature_266_residues
PSDAHSTSSRRNDRMVAILAMLRDRDEVPLRDMASALGASAATIRRDVVSLAEQGLLIRSHGTARRAGTGAELPVNLRDG
RRRRAKEAIAHAVASELPIGRHAIGLTGGTTTTEIVRALHHRHDLTLITNSVSIALEAASQGQQRVLITGGVLRPSSLEL
VGSLAESTFKQVNVGTAIVGCDGMSAEGGLTTHDGIEAATNHTMIKRAAHIIAAVDGSKIGRVTLAKLAEAKDVDLLITD
DSADPEELARLRALGIAIRIVHAPID

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=261, Percent_Identity=31.8007662835249, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789829, Length=231, Percent_Identity=27.7056277056277, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789059, Length=249, Percent_Identity=29.718875502008, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788069, Length=249, Percent_Identity=27.3092369477912, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082344, Length=235, Percent_Identity=29.7872340425532, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787540, Length=251, Percent_Identity=27.8884462151394, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790753, Length=260, Percent_Identity=26.1538461538462, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789170, Length=231, Percent_Identity=25.974025974026, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790635, Length=244, Percent_Identity=29.0983606557377, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787063, Length=239, Percent_Identity=24.2677824267782, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI226510968, Length=244, Percent_Identity=26.6393442622951, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28140; Mature: 28008

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSDAHSTSSRRNDRMVAILAMLRDRDEVPLRDMASALGASAATIRRDVVSLAEQGLLIR
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCEEEE
SHGTARRAGTGAELPVNLRDGRRRRAKEAIAHAVASELPIGRHAIGLTGGTTTTEIVRAL
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
HHRHDLTLITNSVSIALEAASQGQQRVLITGGVLRPSSLELVGSLAESTFKQVNVGTAIV
HHCCCEEEEECCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEE
GCDGMSAEGGLTTHDGIEAATNHTMIKRAAHIIAAVDGSKIGRVTLAKLAEAKDVDLLIT
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCEEEEE
DDSADPEELARLRALGIAIRIVHAPID
CCCCCHHHHHHHHHHHEEEEEEECCCC
>Mature Secondary Structure 
PSDAHSTSSRRNDRMVAILAMLRDRDEVPLRDMASALGASAATIRRDVVSLAEQGLLIR
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCEEEE
SHGTARRAGTGAELPVNLRDGRRRRAKEAIAHAVASELPIGRHAIGLTGGTTTTEIVRAL
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
HHRHDLTLITNSVSIALEAASQGQQRVLITGGVLRPSSLELVGSLAESTFKQVNVGTAIV
HHCCCEEEEECCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEE
GCDGMSAEGGLTTHDGIEAATNHTMIKRAAHIIAAVDGSKIGRVTLAKLAEAKDVDLLIT
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCEEEEE
DDSADPEELARLRALGIAIRIVHAPID
CCCCCHHHHHHHHHHHEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]